RS20090388A - A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one - Google Patents

A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one

Info

Publication number
RS20090388A
RS20090388A RSP-2009/0388A RSP20090388A RS20090388A RS 20090388 A RS20090388 A RS 20090388A RS P20090388 A RSP20090388 A RS P20090388A RS 20090388 A RS20090388 A RS 20090388A
Authority
RS
Serbia
Prior art keywords
octahydrobenzo
isoxazol
benzyl
methyl
salt
Prior art date
Application number
RSP-2009/0388A
Other languages
English (en)
Inventor
Fabio Neggiani
Laura Dini
Original Assignee
Abiogen Pharma S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abiogen Pharma S.P.A. filed Critical Abiogen Pharma S.P.A.
Publication of RS20090388A publication Critical patent/RS20090388A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Predstavljeni pronalazak se odnosi na oksalat so jedinjenja formule (I) u svim njenimstereohemijskim konfiguracijama, na postupak za njenu pripremu i na njenu primenu ulečenju poremećaja raspoloženja, anksioznosti, depresije i konvulzivnih stanja, u poboljšanjusposobnosti učenja, za lečenje amnezije, u rešavanju apstinencijalnog sindroma od droga izloupotrebe lekova. Poželjno, pronalazak se odnosi na oksalat so rel-(3R,3aS,7aS)-3-benzil-2-metil-2,3,3a,4,5, 6,7,7a- oktahidrobenzo[d]izoksazol-4-ona.
RSP-2009/0388A 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one RS20090388A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002102A ITMI20062102A1 (it) 2006-11-02 2006-11-02 Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one
PCT/IB2007/003292 WO2008053326A1 (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one

Publications (1)

Publication Number Publication Date
RS20090388A true RS20090388A (en) 2010-12-31

Family

ID=39145485

Family Applications (2)

Application Number Title Priority Date Filing Date
RSP-2009/0389A RS20090389A (en) 2006-11-02 2007-10-31 A salt of -benzyl -2- metil - 2,3,3a,4,5,6,7,7a-oktahydrobenzo (d)isoxazol -4- one
RSP-2009/0388A RS20090388A (en) 2006-11-02 2007-10-31 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RSP-2009/0389A RS20090389A (en) 2006-11-02 2007-10-31 A salt of -benzyl -2- metil - 2,3,3a,4,5,6,7,7a-oktahydrobenzo (d)isoxazol -4- one

Country Status (20)

Country Link
US (2) US20100069451A1 (sr)
EP (2) EP2094674B1 (sr)
JP (2) JP2010509309A (sr)
KR (2) KR20090077014A (sr)
CN (2) CN101535281A (sr)
AT (2) ATE502021T1 (sr)
AU (2) AU2007315833A1 (sr)
BR (2) BRPI0718392A2 (sr)
CA (2) CA2667513A1 (sr)
DE (2) DE602007013801D1 (sr)
HR (2) HRP20090470A2 (sr)
IL (2) IL198443A0 (sr)
IT (1) ITMI20062102A1 (sr)
MX (2) MX2009004294A (sr)
NO (2) NO20092114L (sr)
NZ (2) NZ577978A (sr)
RS (2) RS20090389A (sr)
RU (2) RU2009120724A (sr)
WO (2) WO2008053326A1 (sr)
ZA (2) ZA200903618B (sr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20080768A1 (it) * 2008-04-24 2009-10-25 Abiogen Pharma Spa Procedimento per la preparazione di un composto in forma cristallina di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidro-benzo[d]isossazol-4-one
EP2112142A1 (en) * 2008-04-24 2009-10-28 Abiogen Pharma S.p.A. Process for preparing a crystalline form compound of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
EP2218721A1 (en) * 2009-02-11 2010-08-18 LEK Pharmaceuticals d.d. Novel salts of sitagliptin
WO2011010332A1 (en) * 2009-07-23 2011-01-27 Abiogen Pharma S.P.A. Process for preparing rel-(3r*,3as*,7as*)-3-benzyl-2-methyl-2,3, 3a,4,5,6,7,7a- octahydrobenzo[d]isoxazoi-4-one or a salt thereof
US10131642B1 (en) * 2015-01-30 2018-11-20 Boehringer Ingelheim International Gmbh Aldosterone synthase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161595A (en) * 1978-10-02 1979-07-17 Bristol-Myers Company Levulinic acid salt
US4419358A (en) * 1981-11-12 1983-12-06 Mead Johnson & Company Isethionic acid salt of 9-cyclohexyl-2-propoxy-9H-purine-6-amine and compositions containing an effective bronchodilating concentration of it
GB2264299B (en) * 1992-02-19 1995-07-26 British Tech Group Iso-oxazolidine derivatives

Also Published As

Publication number Publication date
BRPI0718391A2 (pt) 2013-11-26
BRPI0718392A2 (pt) 2013-11-26
ZA200903810B (en) 2010-07-28
CA2667515A1 (en) 2008-05-08
ATE504578T1 (de) 2011-04-15
ITMI20062102A1 (it) 2008-05-03
IL198444A0 (en) 2010-02-17
NO20092115L (no) 2009-05-29
EP2094674B1 (en) 2011-03-16
NZ577978A (en) 2010-10-29
ZA200903618B (en) 2010-07-28
ATE502021T1 (de) 2011-04-15
WO2008053326A1 (en) 2008-05-08
IL198443A0 (en) 2010-02-17
KR20090082452A (ko) 2009-07-30
JP2010509310A (ja) 2010-03-25
RU2009120724A (ru) 2010-12-10
US20100069450A1 (en) 2010-03-18
KR20090077014A (ko) 2009-07-13
WO2008053325A1 (en) 2008-05-08
EP2094674A1 (en) 2009-09-02
NO20092114L (no) 2009-05-29
AU2007315833A1 (en) 2008-05-08
MX2009004294A (es) 2009-05-08
CA2667513A1 (en) 2008-05-08
MX2009004293A (es) 2009-05-08
EP2094675A1 (en) 2009-09-02
RU2009120667A (ru) 2010-12-10
HRP20090477A2 (hr) 2009-11-30
HRP20090470A2 (hr) 2009-11-30
EP2094675B1 (en) 2011-04-06
AU2007315832A1 (en) 2008-05-08
NZ577311A (en) 2010-10-29
CN101535281A (zh) 2009-09-16
US20100069451A1 (en) 2010-03-18
CN101535282A (zh) 2009-09-16
DE602007013801D1 (de) 2011-05-19
DE602007013278D1 (de) 2011-04-28
RS20090389A (en) 2010-12-31
JP2010509309A (ja) 2010-03-25

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