ZA200903810B - A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one - Google Patents

A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one

Info

Publication number
ZA200903810B
ZA200903810B ZA200903810A ZA200903810A ZA200903810B ZA 200903810 B ZA200903810 B ZA 200903810B ZA 200903810 A ZA200903810 A ZA 200903810A ZA 200903810 A ZA200903810 A ZA 200903810A ZA 200903810 B ZA200903810 B ZA 200903810B
Authority
ZA
South Africa
Prior art keywords
octahydrobenzo
isoxazol
benzyl
methyl
salt
Prior art date
Application number
ZA200903810A
Other languages
English (en)
Inventor
Fabio Neggiani
Laura Dini
Original Assignee
Abiogen Pharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abiogen Pharma Spa filed Critical Abiogen Pharma Spa
Publication of ZA200903810B publication Critical patent/ZA200903810B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200903810A 2006-11-02 2009-06-01 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one ZA200903810B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002102A ITMI20062102A1 (it) 2006-11-02 2006-11-02 Nuovui sali di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidrobenzo-d-isossazol-4-one

Publications (1)

Publication Number Publication Date
ZA200903810B true ZA200903810B (en) 2010-07-28

Family

ID=39145485

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200903618A ZA200903618B (en) 2006-11-02 2009-05-25 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
ZA200903810A ZA200903810B (en) 2006-11-02 2009-06-01 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA200903618A ZA200903618B (en) 2006-11-02 2009-05-25 A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one

Country Status (20)

Country Link
US (2) US20100069451A1 (xx)
EP (2) EP2094675B1 (xx)
JP (2) JP2010509310A (xx)
KR (2) KR20090082452A (xx)
CN (2) CN101535282A (xx)
AT (2) ATE502021T1 (xx)
AU (2) AU2007315832A1 (xx)
BR (2) BRPI0718391A2 (xx)
CA (2) CA2667513A1 (xx)
DE (2) DE602007013801D1 (xx)
HR (2) HRP20090470A2 (xx)
IL (2) IL198444A0 (xx)
IT (1) ITMI20062102A1 (xx)
MX (2) MX2009004294A (xx)
NO (2) NO20092115L (xx)
NZ (2) NZ577978A (xx)
RS (2) RS20090389A (xx)
RU (2) RU2009120667A (xx)
WO (2) WO2008053326A1 (xx)
ZA (2) ZA200903618B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20080768A1 (it) * 2008-04-24 2009-10-25 Abiogen Pharma Spa Procedimento per la preparazione di un composto in forma cristallina di 3-benzil-2-metil-2,3,3a,4,5,6,7,7a-ottaidro-benzo[d]isossazol-4-one
EP2112142A1 (en) * 2008-04-24 2009-10-28 Abiogen Pharma S.p.A. Process for preparing a crystalline form compound of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
EP2218721A1 (en) * 2009-02-11 2010-08-18 LEK Pharmaceuticals d.d. Novel salts of sitagliptin
WO2011010332A1 (en) * 2009-07-23 2011-01-27 Abiogen Pharma S.P.A. Process for preparing rel-(3r*,3as*,7as*)-3-benzyl-2-methyl-2,3, 3a,4,5,6,7,7a- octahydrobenzo[d]isoxazoi-4-one or a salt thereof
US10131642B1 (en) * 2015-01-30 2018-11-20 Boehringer Ingelheim International Gmbh Aldosterone synthase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161595A (en) * 1978-10-02 1979-07-17 Bristol-Myers Company Levulinic acid salt
US4419358A (en) * 1981-11-12 1983-12-06 Mead Johnson & Company Isethionic acid salt of 9-cyclohexyl-2-propoxy-9H-purine-6-amine and compositions containing an effective bronchodilating concentration of it
GB2264299B (en) * 1992-02-19 1995-07-26 British Tech Group Iso-oxazolidine derivatives

Also Published As

Publication number Publication date
HRP20090477A2 (hr) 2009-11-30
IL198443A0 (en) 2010-02-17
RS20090389A (xx) 2010-12-31
US20100069450A1 (en) 2010-03-18
MX2009004294A (es) 2009-05-08
CA2667513A1 (en) 2008-05-08
CN101535282A (zh) 2009-09-16
NO20092114L (no) 2009-05-29
DE602007013278D1 (de) 2011-04-28
RU2009120667A (ru) 2010-12-10
AU2007315832A1 (en) 2008-05-08
RS20090388A (xx) 2010-12-31
DE602007013801D1 (de) 2011-05-19
ITMI20062102A1 (it) 2008-05-03
EP2094675A1 (en) 2009-09-02
KR20090077014A (ko) 2009-07-13
JP2010509309A (ja) 2010-03-25
AU2007315833A1 (en) 2008-05-08
EP2094674A1 (en) 2009-09-02
ZA200903618B (en) 2010-07-28
BRPI0718391A2 (pt) 2013-11-26
NZ577978A (en) 2010-10-29
CA2667515A1 (en) 2008-05-08
HRP20090470A2 (hr) 2009-11-30
BRPI0718392A2 (pt) 2013-11-26
WO2008053325A1 (en) 2008-05-08
WO2008053326A1 (en) 2008-05-08
MX2009004293A (es) 2009-05-08
CN101535281A (zh) 2009-09-16
EP2094674B1 (en) 2011-03-16
ATE502021T1 (de) 2011-04-15
NO20092115L (no) 2009-05-29
EP2094675B1 (en) 2011-04-06
US20100069451A1 (en) 2010-03-18
JP2010509310A (ja) 2010-03-25
IL198444A0 (en) 2010-02-17
RU2009120724A (ru) 2010-12-10
KR20090082452A (ko) 2009-07-30
ATE504578T1 (de) 2011-04-15
NZ577311A (en) 2010-10-29

Similar Documents

Publication Publication Date Title
DE602006021645D1 (de) Verfahren und Zwischenverbindungen zur Herstellung von N4-Phenyl-Quinazolin-4-Amin Derivaten
TW200612892A (en) Novel compounds
TW200510301A (en) Novel compounds
TW200510303A (en) Novel compounds
SE0303180D0 (sv) Novel compounds
SE0301010D0 (sv) Novel compounds
TW200630336A (en) Novel compounds
HRP20050641A2 (en) New carboxylic acids and the esters thereof, pharmaceutical compositions containing these compounds and processes for the preparation thereof
TW200621690A (en) Novel compounds
TW200407305A (en) Novel compounds
WO2008060621A3 (en) Aminopyrrolidines as chemokine receptor antagonists
ZA200903810B (en) A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
ATE463497T1 (de) Neues 1,4-diaza-bicycloä3.2.2ünonyl-oxadiazolyl- derivat und seine medizinische verwendung
TW200624432A (en) Imidazo [1,2-a] pyridine compounds, compositions, uses and methods related thereto
ATE289310T1 (de) Heteroaryl-diazabicycloalkanderivaten als cns- modulatoren
MX2008002805A (es) Derivados de carboxamida como antagonistas del receptor muscarinico.
PL2186782T3 (pl) Sposób oczyszczania produktów znakowanych radioaktywnie z zastosowaniem zmiatacza na stałym nośniku
MY159040A (en) Compounds
EA200600563A1 (ru) Способ получения рензаприда и его промежуточных соединений
ATE460416T1 (de) Neuartige 1,4-diazabicycloä3.2.2ünonan-derivate und deren medizinische verwendung
SE0303451D0 (sv) New compounds
DE60202667D1 (de) Diazabicyclo [2.2.1] heptanderivate
TH82183B (th) อนุพันธ์ของไดไฮโดรเบนโซฟูรานและการใช้อนุพันธ์สารชนิดนี้