ITFE20050003A1 - Agonisti pieni e parziali ed antagonisti del recettore per nocicettina/orfanina fq ad elevata potenza. - Google Patents
Agonisti pieni e parziali ed antagonisti del recettore per nocicettina/orfanina fq ad elevata potenza.Info
- Publication number
- ITFE20050003A1 ITFE20050003A1 IT000003A ITFE20050003A ITFE20050003A1 IT FE20050003 A1 ITFE20050003 A1 IT FE20050003A1 IT 000003 A IT000003 A IT 000003A IT FE20050003 A ITFE20050003 A IT FE20050003A IT FE20050003 A1 ITFE20050003 A1 IT FE20050003A1
- Authority
- IT
- Italy
- Prior art keywords
- nocicettina
- orphanine
- receptor
- partial
- full
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
Priority Applications (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000003A ITFE20050003A1 (it) | 2005-02-15 | 2005-02-15 | Agonisti pieni e parziali ed antagonisti del recettore per nocicettina/orfanina fq ad elevata potenza. |
JP2007554583A JP5281292B2 (ja) | 2005-02-15 | 2006-02-15 | ノシセプチン/オーファニンfq受容体に対する高い活性の全体的及び部分的なアゴニスト及びアンタゴニスト |
CN201510080020.9A CN104689293A (zh) | 2005-02-15 | 2006-02-15 | 一种具有孤啡肽(n/ofq)多肽类似物的药物组合物 |
DK06708285.9T DK1851241T3 (en) | 2005-02-15 | 2006-02-15 | Highly effective whole and partial agonists and antagonists of the nociceptin / orphanin FQ receptor |
MX2007009523A MX2007009523A (es) | 2005-02-15 | 2006-02-15 | Agonistas y antagonistas completos y parciales altamente potentes del receptor nociceptina/orfanina fq. |
HUE06708285A HUE025000T2 (en) | 2005-02-15 | 2006-02-15 | Very effective, complete and partial agonists and antagonists of the nociceptin / orphanin FQ receptor |
PCT/EP2006/050958 WO2006087340A2 (en) | 2005-02-15 | 2006-02-15 | Highly potent full and partial agonists and antagonists of the nociceptin/orphanin fq receptor |
EP06708285.9A EP1851241B1 (en) | 2005-02-15 | 2006-02-15 | Highly potent full and partial agonists and antagonists of the nociceptin/orphanin fq receptor |
UAA200709286A UA91844C2 (ru) | 2005-02-15 | 2006-02-15 | Высокоактивные полные и частичные агонисты и антагонисты рецептора ноцицептина/орфанина fq |
CA2598121A CA2598121C (en) | 2005-02-15 | 2006-02-15 | Highly potent full and partial agonists and antagonists of the nociceptin/orphanin fq receptor |
BRPI0606998A BRPI0606998B8 (pt) | 2005-02-15 | 2006-02-15 | agonistas e antagonistas totais e parciais de alta atividade farmacológica do receptor nociceptina/orfanina fq |
US11/884,241 US8227414B2 (en) | 2005-02-15 | 2006-02-15 | Highly potent full and partial agonists and antagonists of the nociceptin/orphanin FQ receptor |
ES06708285.9T ES2541308T3 (es) | 2005-02-15 | 2006-02-15 | Agonistas y antagonistas completos y parciales altamente potentes del receptor de nociceptina/orfanina FQ |
EA200701732A EA011325B1 (ru) | 2005-02-15 | 2006-02-15 | Высокоэффективные полные и частичные агонисты и антагонисты рецептора ноцицептина/орфанина fq |
SI200631947T SI1851241T1 (sl) | 2005-02-15 | 2006-02-15 | Močno potentni polni in delni agonisti in antagonisti receptorja nociceptina/orfanina fq |
PL06708285T PL1851241T3 (pl) | 2005-02-15 | 2006-02-15 | Bardzo silni pełni i częściowi agoniści i antagoniści receptora nocyceptyny/orfaniny FQ |
KR1020077018487A KR101294895B1 (ko) | 2005-02-15 | 2006-02-15 | 노시셉틴/오파닌 에프큐 수용체의 고강력 완전 및 부분작동물질 및 길항물질 |
RS20150443A RS54095B1 (en) | 2005-02-15 | 2006-02-15 | HIGH-POTENTIAL FULL AND PARTIAL AGONISTS AND ANTAGONISTS OF NOCICEPTINE / ORPHANINE FQ RECEPTORS |
CNA2006800049929A CN101128482A (zh) | 2005-02-15 | 2006-02-15 | 孤啡肽受体的高效全部和部分激动剂和拮抗剂 |
AU2006215639A AU2006215639B2 (en) | 2005-02-15 | 2006-02-15 | Highly potent full and partial agonists and antagonists of the nociceptin/orphanin FQ receptor |
HRP20150731TT HRP20150731T1 (hr) | 2005-02-15 | 2006-02-15 | Visoko potentni potpuni i djelomiäśni agonisti i antagonisti nociceptinskih/orfaninskih fq receptora |
PT67082859T PT1851241E (pt) | 2005-02-15 | 2006-02-15 | Agonistas totais e parciais altamente potentes e antagonistas do recetor da nociceptina/orfanina |
NI200700205A NI200700205A (es) | 2005-02-15 | 2007-08-09 | Agonistas y antagonistas completos y parciales altamente potentes del receptor nociceptina/orfanina fq. |
CU20070195A CU23823A3 (es) | 2005-02-15 | 2007-08-13 | Agonistas y antagonistas completos y parciales altamente potentes del receptor nociceptina/orfanina fq |
IL185235A IL185235A (en) | 2005-02-15 | 2007-08-13 | An analogue of nociceptin / orphanin fq protein and its uses |
MA30190A MA29288B1 (fr) | 2005-02-15 | 2007-08-31 | Agonistes et antagonistes complets et partiels tres puissants du recepteur de la nociceptine/orphanine fq |
ZA200707714A ZA200707714B (en) | 2005-02-15 | 2007-09-07 | Highly potent full and partial agonists and antagonists of the nociceptin/orphanin FQ receptor |
CR9379A CR9379A (es) | 2005-02-15 | 2007-09-13 | Agonistas y antagonistas completos y parciales altamente potentes del receptor nociceptina/orfanina fq |
NO20074702A NO341856B1 (no) | 2005-02-15 | 2007-09-14 | Høyst potente fullstendig eller delvis agonister og antagonister av nociceptin/orfanin FQ reseptoren |
CY20151100579T CY1116456T1 (el) | 2005-02-15 | 2015-07-06 | Υψηλης ικανοτητας, πληρεις και τμηματικοι αγωνιστες και ανταγωνιστες του υποδοχεα nociceptin/orphanin fq |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000003A ITFE20050003A1 (it) | 2005-02-15 | 2005-02-15 | Agonisti pieni e parziali ed antagonisti del recettore per nocicettina/orfanina fq ad elevata potenza. |
Publications (1)
Publication Number | Publication Date |
---|---|
ITFE20050003A1 true ITFE20050003A1 (it) | 2006-08-16 |
Family
ID=36685750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT000003A ITFE20050003A1 (it) | 2005-02-15 | 2005-02-15 | Agonisti pieni e parziali ed antagonisti del recettore per nocicettina/orfanina fq ad elevata potenza. |
Country Status (29)
Country | Link |
---|---|
US (1) | US8227414B2 (it) |
EP (1) | EP1851241B1 (it) |
JP (1) | JP5281292B2 (it) |
KR (1) | KR101294895B1 (it) |
CN (2) | CN101128482A (it) |
AU (1) | AU2006215639B2 (it) |
BR (1) | BRPI0606998B8 (it) |
CA (1) | CA2598121C (it) |
CR (1) | CR9379A (it) |
CU (1) | CU23823A3 (it) |
CY (1) | CY1116456T1 (it) |
DK (1) | DK1851241T3 (it) |
EA (1) | EA011325B1 (it) |
ES (1) | ES2541308T3 (it) |
HR (1) | HRP20150731T1 (it) |
HU (1) | HUE025000T2 (it) |
IL (1) | IL185235A (it) |
IT (1) | ITFE20050003A1 (it) |
MA (1) | MA29288B1 (it) |
MX (1) | MX2007009523A (it) |
NI (1) | NI200700205A (it) |
NO (1) | NO341856B1 (it) |
PL (1) | PL1851241T3 (it) |
PT (1) | PT1851241E (it) |
RS (1) | RS54095B1 (it) |
SI (1) | SI1851241T1 (it) |
UA (1) | UA91844C2 (it) |
WO (1) | WO2006087340A2 (it) |
ZA (1) | ZA200707714B (it) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITNA20090026A1 (it) * | 2009-05-14 | 2010-11-15 | Agostino Bruno D | Agonisti del recettore nop e loro usi terapeutici |
CN112730849B (zh) * | 2021-01-14 | 2023-03-10 | 山西医科大学第二医院 | 内源性孤啡肽作为糖尿病合并无症状性心肌缺血的血清生物标志物的应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1499888T3 (da) * | 2002-04-29 | 2010-10-25 | Euro Celtique Sa | Peptider med indskrænket konformation, der binder sig til ORL-1-receptor |
ITMI20022022A1 (it) * | 2002-09-24 | 2004-03-25 | Girolamo Calo' | Analoghi di nocicettina. |
ITMI20031349A1 (it) * | 2003-07-01 | 2005-01-02 | Ufpeptides S R L | Antagonisti del recettore nop e loro usi terapeutici. |
CN1634980A (zh) * | 2004-10-10 | 2005-07-06 | 兰州大学 | 孤啡肽的类似物 |
-
2005
- 2005-02-15 IT IT000003A patent/ITFE20050003A1/it unknown
-
2006
- 2006-02-15 CN CNA2006800049929A patent/CN101128482A/zh active Pending
- 2006-02-15 CN CN201510080020.9A patent/CN104689293A/zh active Pending
- 2006-02-15 PL PL06708285T patent/PL1851241T3/pl unknown
- 2006-02-15 EA EA200701732A patent/EA011325B1/ru not_active IP Right Cessation
- 2006-02-15 EP EP06708285.9A patent/EP1851241B1/en active Active
- 2006-02-15 JP JP2007554583A patent/JP5281292B2/ja not_active Expired - Fee Related
- 2006-02-15 HR HRP20150731TT patent/HRP20150731T1/hr unknown
- 2006-02-15 DK DK06708285.9T patent/DK1851241T3/en active
- 2006-02-15 RS RS20150443A patent/RS54095B1/en unknown
- 2006-02-15 SI SI200631947T patent/SI1851241T1/sl unknown
- 2006-02-15 AU AU2006215639A patent/AU2006215639B2/en not_active Ceased
- 2006-02-15 MX MX2007009523A patent/MX2007009523A/es active IP Right Grant
- 2006-02-15 HU HUE06708285A patent/HUE025000T2/en unknown
- 2006-02-15 PT PT67082859T patent/PT1851241E/pt unknown
- 2006-02-15 WO PCT/EP2006/050958 patent/WO2006087340A2/en active Application Filing
- 2006-02-15 ES ES06708285.9T patent/ES2541308T3/es active Active
- 2006-02-15 CA CA2598121A patent/CA2598121C/en not_active Expired - Fee Related
- 2006-02-15 UA UAA200709286A patent/UA91844C2/ru unknown
- 2006-02-15 US US11/884,241 patent/US8227414B2/en not_active Expired - Fee Related
- 2006-02-15 KR KR1020077018487A patent/KR101294895B1/ko not_active Expired - Fee Related
- 2006-02-15 BR BRPI0606998A patent/BRPI0606998B8/pt not_active IP Right Cessation
-
2007
- 2007-08-09 NI NI200700205A patent/NI200700205A/es unknown
- 2007-08-13 CU CU20070195A patent/CU23823A3/es active IP Right Grant
- 2007-08-13 IL IL185235A patent/IL185235A/en active IP Right Grant
- 2007-08-31 MA MA30190A patent/MA29288B1/fr unknown
- 2007-09-07 ZA ZA200707714A patent/ZA200707714B/xx unknown
- 2007-09-13 CR CR9379A patent/CR9379A/es not_active Application Discontinuation
- 2007-09-14 NO NO20074702A patent/NO341856B1/no not_active IP Right Cessation
-
2015
- 2015-07-06 CY CY20151100579T patent/CY1116456T1/el unknown
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