DE60333270D1 - Den orl-1-rezeptor bindende peptide mit eingeschränkter konformation - Google Patents

Den orl-1-rezeptor bindende peptide mit eingeschränkter konformation

Info

Publication number
DE60333270D1
DE60333270D1 DE60333270T DE60333270T DE60333270D1 DE 60333270 D1 DE60333270 D1 DE 60333270D1 DE 60333270 T DE60333270 T DE 60333270T DE 60333270 T DE60333270 T DE 60333270T DE 60333270 D1 DE60333270 D1 DE 60333270D1
Authority
DE
Germany
Prior art keywords
orl
present
receptor binding
binding peptides
ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60333270T
Other languages
English (en)
Inventor
Donald J Kyle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of DE60333270D1 publication Critical patent/DE60333270D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE60333270T 2002-04-29 2003-04-29 Den orl-1-rezeptor bindende peptide mit eingeschränkter konformation Expired - Lifetime DE60333270D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37674502P 2002-04-29 2002-04-29
PCT/US2003/013097 WO2003093294A2 (en) 2002-04-29 2003-04-29 Conformationally constrained peptides that bind the orl-1 receptor

Publications (1)

Publication Number Publication Date
DE60333270D1 true DE60333270D1 (de) 2010-08-19

Family

ID=29401398

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60333270T Expired - Lifetime DE60333270D1 (de) 2002-04-29 2003-04-29 Den orl-1-rezeptor bindende peptide mit eingeschränkter konformation

Country Status (12)

Country Link
US (1) US20040259775A1 (de)
EP (1) EP1499888B1 (de)
AT (1) ATE473439T1 (de)
AU (1) AU2003237119A1 (de)
CY (1) CY1111243T1 (de)
DE (1) DE60333270D1 (de)
DK (1) DK1499888T3 (de)
ES (1) ES2348604T3 (de)
HK (1) HK1122098A1 (de)
PT (1) PT1499888E (de)
SI (1) SI1499888T1 (de)
WO (1) WO2003093294A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050266575A1 (en) * 2004-05-27 2005-12-01 Mayo Kevin H Pharmacophores for nociceptin, methods of obtaining and using in screening for nociceptin mimics
ITFE20050003A1 (it) * 2005-02-15 2006-08-16 Ufpeptides S R L Agonisti pieni e parziali ed antagonisti del recettore per nocicettina/orfanina fq ad elevata potenza.
US8703717B2 (en) 2009-02-03 2014-04-22 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
US8680050B2 (en) * 2009-02-03 2014-03-25 Amunix Operating Inc. Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
NZ628987A (en) 2009-02-03 2015-11-27 Amunix Operating Inc Extended recombinant polypeptides and compositions comprising same
US9849188B2 (en) 2009-06-08 2017-12-26 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
NZ621868A (en) * 2009-06-08 2015-10-30 Amunix Operating Inc Growth hormone polypeptides and methods of making and using same
RU2012106820A (ru) 2009-07-27 2013-09-10 Трайджемина Инк. Способы лечения боли
FR2948809B1 (fr) * 2009-07-31 2012-08-17 St Microelectronics Rousset Amplificateur de lecture faible puissance auto-minute
US8557961B2 (en) 2010-04-02 2013-10-15 Amunix Operating Inc. Alpha 1-antitrypsin compositions and methods of making and using same
WO2011123813A2 (en) * 2010-04-02 2011-10-06 Amunix Operating Inc. Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same
WO2014102588A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
US9951038B2 (en) 2012-12-27 2018-04-24 Purdue Pharma L.P. Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
US10118927B2 (en) 2012-12-27 2018-11-06 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
CN107847552B (zh) 2015-01-07 2022-07-01 三叉神经股份公司 含镁的催产素制剂和使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4698327A (en) * 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US5098995A (en) * 1987-05-22 1992-03-24 The Salk Institute For Biological Studies GRF Analogs VIIA
US5639726A (en) * 1994-09-30 1997-06-17 The Regents Of The University Of Michigan Peptide mediated enhancement of thrombolysis methods and compositions
US5821219A (en) * 1995-08-11 1998-10-13 Oregon Health Sciences University Opioid antagonists and methods of their use
WO1999003880A1 (en) * 1997-07-15 1999-01-28 Novo Nordisk A/S Nociceptin analogues
US6777388B1 (en) * 1998-08-21 2004-08-17 Clf Medical Technology Acceleration Program, Inc. Leptin-related peptides
US6586403B1 (en) * 2000-07-20 2003-07-01 Salpep Biotechnology, Inc. Treating allergic reactions and inflammatory responses with tri-and dipeptides
WO2003088914A2 (en) * 2002-04-18 2003-10-30 The University Of Iowa Research Foundation Methods of inhibiting and treating bacterial biofilms by metal chelators

Also Published As

Publication number Publication date
DK1499888T3 (da) 2010-10-25
CY1111243T1 (el) 2015-06-11
AU2003237119A1 (en) 2003-11-17
PT1499888E (pt) 2010-10-14
ES2348604T3 (es) 2010-12-09
SI1499888T1 (sl) 2010-11-30
US20040259775A1 (en) 2004-12-23
WO2003093294A3 (en) 2004-09-23
AU2003237119A8 (en) 2003-11-17
EP1499888A4 (de) 2005-10-19
EP1499888A2 (de) 2005-01-26
ATE473439T1 (de) 2010-07-15
EP1499888B1 (de) 2010-07-07
WO2003093294A2 (en) 2003-11-13
HK1122098A1 (en) 2009-05-08

Similar Documents

Publication Publication Date Title
HK1122098A1 (en) Conformationally constrained peptides that bind the orl-1 receptor
Hruby et al. Conformation–activity relationships of opioid peptides with selective activities at opioid receptors
EE200200510A (et) POL1212 aminohappejärjestust kodeeriv DNA, seda sisaldav ekspressioonivektor, sea modifitseeritud VIII- tegur, sellel põhinev ravimkompositsioon ningmeetod sea modifitseeritud VIII-teguri aminohappejärjestust omava valgu valmistamiseks
DE69823520D1 (de) Noribogain zur behandlung von schmerzen und drogenabhängigkeit
ATE361318T1 (de) Polypeptiden, die die april-vermittelte aktivierung von t-und b-zellen hemmen
RU2008121750A (ru) Ионофоретическая доставка ротиготина для лечения болезни паркинсона
DK1248643T3 (da) Anvendelse af copolymer 1 og beslægtede peptider og polypeptider og T-celler behandlet dermed til neurobeskyttende terapi
IS4261A (is) Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
BR0309550A (pt) analgésicos hìbridos quiméricos
DE69736634D1 (de) Antagonisten des intestinotrophen glp-2 peptides
EA200701541A1 (ru) Применение оксикодона для лечения висцеральной боли
CN101454338A (zh) κ阿片样受体肽的N-氧化物
Martin et al. Biodegradable amphipathic peptide hydrogels as extended-release system for opioid peptides
DE602004006869D1 (de) 5ht2c rezeptor agonisten zur behandlung von diabetes und fettleibigkeit
CY1110152T1 (el) Χρηση συνδυασμου μορφινης και τουλαχιστον ενος ανταγωνιστη φυσικου οπιοειδους στην αγωγη της εξαρτησης απο φυσικα οπιοειδη και στην προληψη της μη στοματικης καταχρησης φυσικων οπιοειδων σε εξαρτημενους απο φυσικα οπιοειδη
HUP0401915A2 (hu) 4-[4-Piperidinilidén-(3-karbamoil-fenil)-metil]-benzamid-származékok és alkalmazásuk fájdalom, gerincsérülések vagy gasztrointesztinális rendellenességek kezelésére és ezeket tartalmazó gyógyszerkészítmények
BR0009472A (pt) Antagonistas de lhrh com propriedades desolubilidade aperfeiçoadas
Hingne et al. Blockade of NMDA receptors prevents analgesic tolerance to repeated transcutaneous electrical nerve stimulation (TENS) in rats
DE60218843D1 (de) Verfahren zur identifizierung von mitteln zur behandlung von diabetes
Hiramatsu et al. Long‐lasting antinociceptive effects of a novel dynorphin analogue, Tyr‐D‐Ala‐Phe‐Leu‐Arg ψ (CH2NH) Arg‐NH2, in mice
WO2007144979A1 (ja) ペプチド誘導体
EA200801077A1 (ru) Антагонисты взаимодействия pf4 и rantes
KR100488038B1 (ko) 기관 보호 활성을 지닌 신규한 신체 보호 화합물 펩티드염, 이의 제조 방법 및 치료에서의 이의 용도
ATE554793T1 (de) Konjugat
WO2002070696A3 (en) Cd109 nucleic acid molecules polypeptides and methods of use