PT1499888E - Péptidos conformacionalmente constrangidos que se ligam ao receptor orl-1 - Google Patents
Péptidos conformacionalmente constrangidos que se ligam ao receptor orl-1 Download PDFInfo
- Publication number
- PT1499888E PT1499888E PT03736501T PT03736501T PT1499888E PT 1499888 E PT1499888 E PT 1499888E PT 03736501 T PT03736501 T PT 03736501T PT 03736501 T PT03736501 T PT 03736501T PT 1499888 E PT1499888 E PT 1499888E
- Authority
- PT
- Portugal
- Prior art keywords
- orl
- receptor
- present
- conformationally constrained
- bind
- Prior art date
Links
- 108010020615 nociceptin receptor Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 239000003446 ligand Substances 0.000 abstract 3
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 206010012335 Dependence Diseases 0.000 abstract 1
- 206010052804 Drug tolerance Diseases 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000816 peptidomimetic Substances 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37674502P | 2002-04-29 | 2002-04-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1499888E true PT1499888E (pt) | 2010-10-14 |
Family
ID=29401398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03736501T PT1499888E (pt) | 2002-04-29 | 2003-04-29 | Péptidos conformacionalmente constrangidos que se ligam ao receptor orl-1 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20040259775A1 (pt) |
| EP (1) | EP1499888B1 (pt) |
| AT (1) | ATE473439T1 (pt) |
| AU (1) | AU2003237119A1 (pt) |
| CY (1) | CY1111243T1 (pt) |
| DE (1) | DE60333270D1 (pt) |
| DK (1) | DK1499888T3 (pt) |
| ES (1) | ES2348604T3 (pt) |
| HK (1) | HK1122098A1 (pt) |
| PT (1) | PT1499888E (pt) |
| SI (1) | SI1499888T1 (pt) |
| WO (1) | WO2003093294A2 (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050266575A1 (en) * | 2004-05-27 | 2005-12-01 | Mayo Kevin H | Pharmacophores for nociceptin, methods of obtaining and using in screening for nociceptin mimics |
| ITFE20050003A1 (it) * | 2005-02-15 | 2006-08-16 | Ufpeptides S R L | Agonisti pieni e parziali ed antagonisti del recettore per nocicettina/orfanina fq ad elevata potenza. |
| US8680050B2 (en) * | 2009-02-03 | 2014-03-25 | Amunix Operating Inc. | Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same |
| US8703717B2 (en) | 2009-02-03 | 2014-04-22 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| DK2393828T3 (en) | 2009-02-03 | 2017-01-23 | Amunix Operating Inc | Extended recombinant polypeptides and compositions comprising same |
| DK2440241T3 (en) * | 2009-06-08 | 2017-10-02 | Amunix Operating Inc | GROWTH HORMON POLYPEPTIDES AND PROCEDURES FOR PREPARING AND USING THEREOF |
| US9849188B2 (en) | 2009-06-08 | 2017-12-26 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| SG177752A1 (en) | 2009-07-27 | 2012-03-29 | Trigemina Inc | Methods for treatment of pain |
| FR2948809B1 (fr) * | 2009-07-31 | 2012-08-17 | St Microelectronics Rousset | Amplificateur de lecture faible puissance auto-minute |
| WO2011123830A2 (en) | 2010-04-02 | 2011-10-06 | Amunix Operating Inc. | Alpha 1-antitrypsin compositions and methods of making and using same |
| WO2011123813A2 (en) * | 2010-04-02 | 2011-10-06 | Amunix Operating Inc. | Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same |
| WO2014102590A1 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Substituted piperidin-4-amino-type compounds and uses thereof |
| WO2014102588A2 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Indole and indoline-type piperidine compounds and uses thereof |
| US9951038B2 (en) | 2012-12-27 | 2018-04-24 | Purdue Pharma L.P. | Quinazolin-4(3H)-one-type piperidine compounds and uses thereof |
| JP7030517B2 (ja) | 2015-01-07 | 2022-03-07 | トライジェミナ， インコーポレイテッド | マグネシウム含有オキシトシン製剤および使用の方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4698327A (en) * | 1985-04-25 | 1987-10-06 | Eli Lilly And Company | Novel glycopeptide derivatives |
| US5098995A (en) * | 1987-05-22 | 1992-03-24 | The Salk Institute For Biological Studies | GRF Analogs VIIA |
| US5639726A (en) * | 1994-09-30 | 1997-06-17 | The Regents Of The University Of Michigan | Peptide mediated enhancement of thrombolysis methods and compositions |
| US5821219A (en) * | 1995-08-11 | 1998-10-13 | Oregon Health Sciences University | Opioid antagonists and methods of their use |
| AU8334298A (en) * | 1997-07-15 | 1999-02-10 | Novo Nordisk A/S | Nociceptin analogues |
| US6777388B1 (en) * | 1998-08-21 | 2004-08-17 | Clf Medical Technology Acceleration Program, Inc. | Leptin-related peptides |
| US6586403B1 (en) * | 2000-07-20 | 2003-07-01 | Salpep Biotechnology, Inc. | Treating allergic reactions and inflammatory responses with tri-and dipeptides |
| AU2003225073A1 (en) * | 2002-04-18 | 2003-11-03 | The University Of Iowa Research Foundation | Methods of inhibiting and treating bacterial biofilms by metal chelators |
-
2003
- 2003-04-29 AU AU2003237119A patent/AU2003237119A1/en not_active Abandoned
- 2003-04-29 WO PCT/US2003/013097 patent/WO2003093294A2/en not_active Application Discontinuation
- 2003-04-29 EP EP03736501A patent/EP1499888B1/en not_active Expired - Lifetime
- 2003-04-29 PT PT03736501T patent/PT1499888E/pt unknown
- 2003-04-29 ES ES03736501T patent/ES2348604T3/es not_active Expired - Lifetime
- 2003-04-29 DE DE60333270T patent/DE60333270D1/de not_active Expired - Lifetime
- 2003-04-29 US US10/425,568 patent/US20040259775A1/en not_active Abandoned
- 2003-04-29 SI SI200331876T patent/SI1499888T1/sl unknown
- 2003-04-29 AT AT03736501T patent/ATE473439T1/de active
- 2003-04-29 DK DK03736501.2T patent/DK1499888T3/da active
-
2008
- 2008-12-03 HK HK08113163.6A patent/HK1122098A1/xx not_active IP Right Cessation
-
2010
- 2010-10-07 CY CY20101100900T patent/CY1111243T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1499888T1 (sl) | 2010-11-30 |
| CY1111243T1 (el) | 2015-06-11 |
| DK1499888T3 (da) | 2010-10-25 |
| ATE473439T1 (de) | 2010-07-15 |
| EP1499888A2 (en) | 2005-01-26 |
| AU2003237119A8 (en) | 2003-11-17 |
| EP1499888B1 (en) | 2010-07-07 |
| WO2003093294A3 (en) | 2004-09-23 |
| DE60333270D1 (de) | 2010-08-19 |
| EP1499888A4 (en) | 2005-10-19 |
| AU2003237119A1 (en) | 2003-11-17 |
| WO2003093294A2 (en) | 2003-11-13 |
| US20040259775A1 (en) | 2004-12-23 |
| HK1122098A1 (en) | 2009-05-08 |
| ES2348604T3 (es) | 2010-12-09 |
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