IT8748495A0 - Composizione di collirio isotonico umettante - Google Patents

Composizione di collirio isotonico umettante

Info

Publication number
IT8748495A0
IT8748495A0 IT8748495A IT4849587A IT8748495A0 IT 8748495 A0 IT8748495 A0 IT 8748495A0 IT 8748495 A IT8748495 A IT 8748495A IT 4849587 A IT4849587 A IT 4849587A IT 8748495 A0 IT8748495 A0 IT 8748495A0
Authority
IT
Italy
Prior art keywords
humectant
composition
eye drops
isotonic
isotonic eye
Prior art date
Application number
IT8748495A
Other languages
English (en)
Other versions
IT1211852B (it
Inventor
Dikstein Shabtay
Original Assignee
Res & Dev Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11057204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT8748495(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Res & Dev Co Ltd filed Critical Res & Dev Co Ltd
Publication of IT8748495A0 publication Critical patent/IT8748495A0/it
Application granted granted Critical
Publication of IT1211852B publication Critical patent/IT1211852B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT8748495A 1986-10-14 1987-10-13 Composizione di collirio isotonico umettante IT1211852B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL80298A IL80298A (en) 1986-10-14 1986-10-14 Eye drops

Publications (2)

Publication Number Publication Date
IT8748495A0 true IT8748495A0 (it) 1987-10-13
IT1211852B IT1211852B (it) 1989-11-03

Family

ID=11057204

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8748495A IT1211852B (it) 1986-10-14 1987-10-13 Composizione di collirio isotonico umettante

Country Status (8)

Country Link
US (1) US5106615A (it)
CA (1) CA1311418C (it)
DE (1) DE3734835C2 (it)
FR (1) FR2604906B1 (it)
GB (1) GB2196255B (it)
IL (1) IL80298A (it)
IT (1) IT1211852B (it)
SE (1) SE503469C2 (it)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0323522A4 (en) * 1987-07-07 1989-08-30 Santen Pharmaceutical Co Ltd ARTIFICIAL TEAR.
AU655919B2 (en) * 1990-02-22 1995-01-19 Macnaught Pty Limited Artificial tears
JP2873530B2 (ja) * 1991-12-13 1999-03-24 参天製薬株式会社 ニュートン型粘性を示すカルボキシビニルポリマー含有点眼液基剤
IL101056A (en) * 1992-02-24 1997-03-18 Res & Dev Co Ltd Composition for nasal treatment
DE4225489A1 (de) * 1992-07-30 1994-02-03 Michael Prof Dr Rer Na Dittgen Verfahren zur Herstellung bioadhäsiver Augentropfen
DE4229494A1 (de) * 1992-09-04 1994-03-10 Basotherm Gmbh Arzneimittel zur topischen Anwendung am Auge zur Behandlung des erhöhten intraokularen Drucks
US5358706A (en) * 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
US5645827A (en) * 1992-09-30 1997-07-08 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
CA2125060C (en) * 1993-07-02 1999-03-30 Henry P. Dabrowski Ophthalmic solution for artificial tears
FR2717691B1 (fr) * 1994-03-22 1998-02-13 Europhta Laboratoire Nouveaux gels ophtalmiques et leur procédé d'obtention.
IT1273011B (it) 1994-07-25 1997-07-01 Trhecnopharma S A Preparato oftalmico per l'uso come lacrima artificiale
IT1274984B (it) * 1994-12-09 1997-07-29 Technopharma Sa Soluzioni viscosizzate con ialuronato di sodio per l'uso come fluido maschera nella fotocheratectomia terapeutica mediante laser a accimeri
US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
DE69637625D1 (de) * 1995-10-19 2008-09-18 Bio Origyn Llc Methoden und zusammensetzungen, die das ueberleben und die funktion von keimbahnzellen und embryonen verbessern
IT1277707B1 (it) 1995-12-22 1997-11-11 Chemedica Sa Formulazione oftalmica a base di ialuronato di sodio per uso nella chirurgia oculare
WO1997045102A1 (en) * 1996-05-31 1997-12-04 Schwadrohn, Gérard Novel therapeutic use of ophthalmic gels
US5840046A (en) * 1996-06-21 1998-11-24 Medtronic, Inc. Guidewire having hydrophilic coating
US5800807A (en) * 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
US6277365B1 (en) 1997-09-18 2001-08-21 Bausch & Lomb Incorporated Ophthalmic composition including a cationic glycoside and an anionic therapeutic agent
AU754064B2 (en) * 1998-05-15 2002-11-07 Wakamoto Pharmaceutical Co., Ltd. Anti-inflammatory eye drops
CA2362498A1 (en) 1999-03-01 2000-09-08 Vista Scientific Llc Mucin containing ophthalmic preparations
US6703039B2 (en) 2000-12-06 2004-03-09 Bausch & Lomb Incorporated Reversible gelling system for ocular drug delivery
AU2002230504A1 (en) 2000-12-20 2002-07-01 Alcon Universal Ltd. Ophthalmic irrigating solution adapted for use in lasik surgery
WO2002049611A2 (en) * 2000-12-20 2002-06-27 Alcon, Inc. Ophthalmic lubricating solution adapted for use in lasik surgery
US20050143471A1 (en) * 2001-10-22 2005-06-30 Shen Gao Taste masking spill-resistant formulation
US20030235618A1 (en) * 2001-10-22 2003-12-25 Taro Pharmaceutical Industries Ltd. Taste masking spill-resistant formulation
US6656460B2 (en) 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
US7045121B2 (en) 2001-12-14 2006-05-16 Allergan, Inc. Ophthalmic compositions for lubricating eyes and methods for making and using same
WO2003059263A2 (en) * 2001-12-21 2003-07-24 Alcon, Inc. Inorganic nanoparticles to modify the viscosity and physical properties of ophthalmic and otic compositions.
US20050003014A1 (en) 2001-12-21 2005-01-06 Ketelson Howard Allen Use of synthetic inorganic nanoparticles as carriers for ophthalmic and otic drugs
CN102178692A (zh) * 2002-07-03 2011-09-14 派瑞克科学公司 透明质酸组合物以及使用方法
US20040137079A1 (en) * 2003-01-08 2004-07-15 Cook James N. Contact lens and eye drop rewetter compositions and methods
ES2375565T3 (es) 2003-08-07 2012-03-02 Healor Ltd. Composiciones farmacéuticas y métodos para acelerar la cicatrización de heridas.
WO2005014046A2 (en) 2003-08-07 2005-02-17 Allergan, Inc. Compositions for delivery of therapeutics into the eyes and methods for making and using the same
RU2336074C2 (ru) * 2003-11-12 2008-10-20 Аллерган, Инк. Композиции и способы лечения заднего сегмента глаза
US20060141049A1 (en) * 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20050101582A1 (en) * 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20070224278A1 (en) * 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
ES2318453T3 (es) 2004-01-20 2009-05-01 Allergan, Inc. Composiciones para terapia localizada del ojo, que comprenden, de preferencia,triamcinolona acetonida y acido hialuronico.
EP1720518B1 (en) * 2004-02-26 2009-08-12 Bausch & Lomb Incorporated Alginate viscoelastic composition, method of use and package
US7842382B2 (en) * 2004-03-11 2010-11-30 Knauf Insulation Gmbh Binder compositions and associated methods
US8147865B2 (en) * 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
US8119154B2 (en) * 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
JP2008505978A (ja) * 2004-07-12 2008-02-28 アラーガン、インコーポレイテッド 眼病用組成物および眼病治療法
US20080307751A1 (en) * 2004-10-01 2008-12-18 Newman Stephen D Contact Lens Package Solution
US8603631B2 (en) * 2004-10-13 2013-12-10 Knauf Insulation Gmbh Polyester binding compositions
WO2006043965A1 (en) * 2004-10-14 2006-04-27 Allergan, Inc. Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods
US9297928B2 (en) * 2004-11-22 2016-03-29 Johnson & Johnson Vision Care, Inc. Ophthalmic compositions comprising polyether substituted polymers
US7726809B2 (en) * 2005-02-09 2010-06-01 Safilens S.R.L. Contact lens, method for producing same, and pack for storage and maintenance of a contact lens
TW200722109A (en) * 2005-03-31 2007-06-16 Bausch & Lomb Polysaccharide and polyol composition for treating dry eye and related methods of manufacture and methods of use
TWI393567B (zh) * 2005-03-31 2013-04-21 Bausch & Lomb 治療乾眼之組合物及相關之製造方法及使用方法
IL168603A (en) 2005-05-16 2011-05-31 Resdevco Res And Dev Co Pharmaceutical or cosmetic composition for the prevention and treatment of irritation of mucous cells or skin cells
US10183076B2 (en) 2005-05-16 2019-01-22 Resdevco Research And Development Co. L Topical compositions for treatment of irritation of mucous membranes
TR201508968T3 (tr) * 2005-07-26 2015-08-21 Knauf Insulation Gmbh Fiberglas yalıtım ürünlerinin üretimine ilişkin bir yöntem.
US8367606B2 (en) * 2005-08-29 2013-02-05 Healor Ltd. Method and compositions for prevention and treatment of diabetic and aged skin
FR2895907B1 (fr) * 2006-01-06 2012-06-01 Anteis Sa Gel viscoelastique a usage dermatologique
US20070195261A1 (en) 2006-02-17 2007-08-23 Jurgen Vogt Method for sterilization of hydrogel contact lenses
ES2834151T3 (es) 2007-01-25 2021-06-16 Knauf Insulation Gmbh Aglutinantes y materiales elaborados con los mismos
EP2450493B1 (en) 2007-01-25 2024-10-02 Knauf Insulation SPRL Mineral fibre board
BRPI0721233A2 (pt) 2007-01-25 2013-01-01 Knauf Insulation Ltd produto isolante de fibra mineral sem formaldeìdo
CN101720341B (zh) 2007-01-25 2013-06-12 克瑙夫绝缘私人有限公司 复合木板
US20100084598A1 (en) * 2007-01-25 2010-04-08 Roger Jackson Mineral fibre insulation
EP2137223B1 (en) 2007-04-13 2019-02-27 Knauf Insulation GmbH Composite maillard-resole binders
US10028976B2 (en) 2007-07-02 2018-07-24 Aptissen Sa Injectable formulation of natural polysaccharide and polyol for treatment of osteoarthritis
FR2918276B1 (fr) * 2007-07-02 2010-01-22 Anteis Sa "utilisation d'un gel de polysaccharide(s)naturel(s)pour la preparation d'une formulation injectable de traitement des degenerescences articulaires"
CN101802031B (zh) * 2007-07-05 2012-10-17 可耐福保温材料有限公司 羟基单羧酸基梅拉德粘结剂
CN102755649A (zh) * 2007-07-30 2012-10-31 希尔洛有限公司 药物组合物及相关方法
US20090036404A1 (en) * 2007-08-02 2009-02-05 Macleod Steven K Ophthalmic compositions comprising a carboxyl-modified fructan or a salt thereof
GB0715100D0 (en) 2007-08-03 2007-09-12 Knauf Insulation Ltd Binders
ITRM20070510A1 (it) * 2007-10-02 2009-04-03 Rmfa Trading S A Composizioni oftalmiche a base di polisaccaride del seme di tamarindo e acido ialuronico.
US20170354624A1 (en) * 2007-11-14 2017-12-14 Resdevco Research And Development Co. Ltd. Topical compositions for treatment of skin irritation
US7842714B2 (en) 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
US9192571B2 (en) * 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
CA2770396A1 (en) 2009-08-07 2011-02-10 Knauf Insulation Molasses binder
US8921337B2 (en) 2009-12-03 2014-12-30 Alcon Research, Ltd. Carboxyvinyl polymer-containing nanoparticle suspensions
RU2012133148A (ru) 2010-01-11 2014-02-20 Хилор Лтд. Способ лечения воспалительного заболевания и расстройства
CN103025777B (zh) 2010-05-07 2016-01-20 克瑙夫绝缘私人有限公司 碳水化合物粘合剂及用其制备的材料
AU2011249759B2 (en) 2010-05-07 2014-11-06 Knauf Insulation Carbohydrate polyamine binders and materials made therewith
WO2011154368A1 (en) 2010-06-07 2011-12-15 Knauf Insulation Fiber products having temperature control additives
FR2961694B1 (fr) 2010-06-29 2013-01-25 Thea Lab Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur
CA2812164A1 (en) 2010-11-08 2012-05-18 Healor Ltd. Buffered ophthalmic compositions and methods of use thereof
IL212725A (en) * 2011-05-05 2016-06-30 Resdevco Res And Dev Co Glycerol Preparation for Non-surgical Conjunctivochalysis
US20140186635A1 (en) 2011-05-07 2014-07-03 Knauf Insulation Liquid high solids binder composition
GB201206193D0 (en) 2012-04-05 2012-05-23 Knauf Insulation Ltd Binders and associated products
GB201214734D0 (en) 2012-08-17 2012-10-03 Knauf Insulation Ltd Wood board and process for its production
ES2921601T3 (es) 2012-12-05 2022-08-30 Knauf Insulation Sprl Aglutinante
NZ709620A (en) 2013-01-23 2020-07-31 Semnur Pharmaceuticals Inc Pharmaceutical formulation comprising an insoluble corticosteroid and a soluble corticosteroid
US20140378401A1 (en) * 2013-06-21 2014-12-25 Gnt, Llc Ophthalmic Lipophilic and Hydrophilic Drug Delivery Vehicle Formulations
PL3102587T3 (pl) 2014-02-07 2019-01-31 Knauf Insulation, Inc. Nieutwardzone wyroby o ulepszonym okresie trwałości
GB201408909D0 (en) 2014-05-20 2014-07-02 Knauf Insulation Ltd Binders
GB201412709D0 (en) 2014-07-17 2014-09-03 Knauf Insulation And Knauf Insulation Ltd Improved binder compositions and uses thereof
TWI674899B (zh) * 2015-01-21 2019-10-21 美商桑紐爾製藥公司 醫藥配方
GB201517867D0 (en) 2015-10-09 2015-11-25 Knauf Insulation Ltd Wood particle boards
GB201610063D0 (en) 2016-06-09 2016-07-27 Knauf Insulation Ltd Binders
GB201701569D0 (en) 2017-01-31 2017-03-15 Knauf Insulation Ltd Improved binder compositions and uses thereof
RU2019130955A (ru) * 2017-03-05 2021-04-07 Ресдевко Рисёрч Энд Дивелопмент Ко. Лтд. Глазные капли для лечения раздражения, не вызванного инфекцией
GB201804908D0 (en) 2018-03-27 2018-05-09 Knauf Insulation Ltd Binder compositions and uses thereof
GB201804907D0 (en) 2018-03-27 2018-05-09 Knauf Insulation Ltd Composite products
WO2021156856A1 (en) 2020-02-03 2021-08-12 Resdevco Research And Development Co. Ltd. Topical opthalmological composition containing hyaluronate and taurine having non-newtonian rheological properties

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB904797A (en) * 1959-12-23 1962-08-29 Boots Pure Drug Co Ltd Ophthalmic medicaments comprising phenanthridinium salts
GB1044449A (en) * 1965-05-18 1966-09-28 Boots Pure Drug Co Ltd Improvements in ophthalmic preparations
US4201706A (en) * 1978-09-22 1980-05-06 Burton, Parsons & Company, Inc. Treatment of corneal edema
DE3167270D1 (en) * 1980-03-21 1985-01-03 Wellcome Found Stabilised ophthalmic formulation
US4396625A (en) * 1980-05-13 1983-08-02 Sumitomo Chemical Company, Limited Treatment of glaucoma or ocular hypertension and ophthalmic composition
IE51421B1 (en) * 1980-08-01 1986-12-24 Smith & Nephew Ass Ophthalmic compositions containing triamterene
GB2090013B (en) * 1980-12-18 1984-04-11 Smith & Nephew Ass Soft contact lens sterilising solution
JPS5857319A (ja) * 1981-09-30 1983-04-05 Green Cross Corp:The 高粘性ヒアルロン酸製剤
FR2518882A1 (fr) * 1981-12-30 1983-07-01 Pos Lab Composition therapeutique, a base de monophosphate d'inosine, pour le traitement des troubles d'accommodation de l'oeil
US4540568A (en) * 1982-10-14 1985-09-10 Trager Seymour F Injectionable viscoelastic ophthalmic gel
US4470965A (en) * 1982-10-27 1984-09-11 Usv Pharmaceutical Corporation Celiprolol for the treatment of glaucoma
EP0145710A1 (en) * 1983-05-25 1985-06-26 Alcon Laboratories, Inc. Ophthalmic solution
EP0145714A1 (en) * 1983-05-25 1985-06-26 Alcon Laboratories, Inc. Ophthalmic gel
PH21406A (en) * 1985-04-19 1987-10-15 Ciba Geigy Ag Ophthalmic solution and methods for improving the comfort and safety of contact lenses
US4620979A (en) * 1985-08-02 1986-11-04 Schachar Ronald A Ophthalmological irrigating solution containing ascorbate

Also Published As

Publication number Publication date
IL80298A (en) 1993-01-31
GB2196255A (en) 1988-04-27
CA1311418C (en) 1992-12-15
DE3734835A1 (de) 1988-06-01
GB8724112D0 (en) 1987-11-18
SE8703972L (sv) 1988-04-15
SE8703972D0 (sv) 1987-10-13
FR2604906A1 (fr) 1988-04-15
SE503469C2 (sv) 1996-06-24
GB2196255B (en) 1991-05-15
IT1211852B (it) 1989-11-03
FR2604906B1 (fr) 1992-02-07
DE3734835C2 (de) 1997-07-17
IL80298A0 (en) 1987-01-30
US5106615A (en) 1992-04-21

Similar Documents

Publication Publication Date Title
IT8748495A0 (it) Composizione di collirio isotonico umettante
FI93223B (fi) Liimakoostumuksia
BR8700056A (pt) Composicao organopolisiloxano
IT1223773B (it) Composizioni vulcanizzabili di organopolisilossani
KR880701768A (ko) 윤활유 조성물
KR880701769A (ko) 윤활유 조성물
BR6401425U (pt) Disposicao construtiva de protese peniana
IT8548703A0 (it) Formulazioni oftalmiche comprendenti bromocriptina
DK319885A (da) Aminophenolforbindelser
FI884720A7 (fi) Varjoaineina käytettäviä koostumuksia
IT8420690A1 (it) Composizione di inchiostro
BR8704087A (pt) Composicao
IT1184213B (it) Tenuta per stato di inattivita'
IT1163931B (it) Composizione e metodo per impedire la formazione di incrostazioni
FI874844A7 (fi) Liimakoostumuksia
BR8805753A (pt) Composicao
BR8805083A (pt) Composicao
RO95836A (ro) Compozitie erbicida lichida
LV5649A3 (lv) Herbicida kompozicija
IT1203998B (it) Metodo per prevenire l'appannamento di superfici
BR8806938A (pt) Composicao oleaginosa
IT1199948B (it) Composizioni farmaceutiche comprendenti la bromocriptina
TR22560A (tr) Sulfonilguanidinopirimidin tuerevleri
FR2597117B1 (fr) Composition anti-corrosion
FR2566077B1 (fr) Couple de ressorts kedves en s " balance kedves "

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960909