IT1294797B1 - Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante - Google Patents

Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante

Info

Publication number
IT1294797B1
IT1294797B1 IT97PD000170A ITPD970170A IT1294797B1 IT 1294797 B1 IT1294797 B1 IT 1294797B1 IT 97PD000170 A IT97PD000170 A IT 97PD000170A IT PD970170 A ITPD970170 A IT PD970170A IT 1294797 B1 IT1294797 B1 IT 1294797B1
Authority
IT
Italy
Prior art keywords
physical
preparation
biomaterials
buffering
hyaluronic acid
Prior art date
Application number
IT97PD000170A
Other languages
English (en)
Italian (it)
Inventor
Alberto Rivarossa
Daniele Pressato
Original Assignee
Fidia Advanced Biopolymers Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IT97PD000170A priority Critical patent/IT1294797B1/it
Application filed by Fidia Advanced Biopolymers Srl filed Critical Fidia Advanced Biopolymers Srl
Priority to IL13414098A priority patent/IL134140A0/xx
Priority to PCT/EP1998/004716 priority patent/WO1999004828A2/en
Priority to JP2000503879A priority patent/JP4417547B2/ja
Priority to AU92555/98A priority patent/AU749627B2/en
Priority to ES98945104T priority patent/ES2253827T3/es
Priority to DE69832616T priority patent/DE69832616T2/de
Priority to CA002298733A priority patent/CA2298733C/en
Priority to HK00107189.6A priority patent/HK1028210B/en
Priority to AT98945104T priority patent/ATE311208T1/de
Priority to DK98945104T priority patent/DK0999859T3/da
Priority to EP98945104A priority patent/EP0999859B1/en
Publication of ITPD970170A1 publication Critical patent/ITPD970170A1/it
Application granted granted Critical
Publication of IT1294797B1 publication Critical patent/IT1294797B1/it
Priority to IL134140A priority patent/IL134140A/en
Priority to US10/139,878 priority patent/US7202230B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IT97PD000170A 1997-07-28 1997-07-28 Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante IT1294797B1 (it)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IT97PD000170A IT1294797B1 (it) 1997-07-28 1997-07-28 Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante
HK00107189.6A HK1028210B (en) 1997-07-28 1998-07-28 Use of hyaluronic acid derivatives in the preparation of biomaterials
JP2000503879A JP4417547B2 (ja) 1997-07-28 1998-07-28 物理的な止血活性および塞栓活性、および吻合後の癒着形成についての予防活性を有している生体適合材料の製造におけるヒアルロン酸誘導体の使用
AU92555/98A AU749627B2 (en) 1997-07-28 1998-07-28 Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity and a preventive activity in the formation of adhesions following anastomosis
ES98945104T ES2253827T3 (es) 1997-07-28 1998-07-28 Uso de derivados de acido hialuronico en la preparacion de biomateriales.
DE69832616T DE69832616T2 (de) 1997-07-28 1998-07-28 Verwendung von hyaluonsäurederivaten zur herstellung von biomaterial
IL13414098A IL134140A0 (en) 1997-07-28 1998-07-28 Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity and a preventive activity in the formation of adhesion following anastomosis
PCT/EP1998/004716 WO1999004828A2 (en) 1997-07-28 1998-07-28 Use of hyaluronic acid derivatives in the preparation of biomaterials
AT98945104T ATE311208T1 (de) 1997-07-28 1998-07-28 Verwendung von hyaluonsäurederivaten zur herstellung von biomaterial
DK98945104T DK0999859T3 (da) 1997-07-28 1998-07-28 Anvendelse af hyaluronsyrederivater til fremstilling af biomaterialer
EP98945104A EP0999859B1 (en) 1997-07-28 1998-07-28 Use of hyaluronic acid derivatives in the preparation of biomaterials
CA002298733A CA2298733C (en) 1997-07-28 1998-07-28 Hyaluronic acid derivatives for the preparation of haemostatic biomaterials for use following anastomosis
IL134140A IL134140A (en) 1997-07-28 2000-01-20 Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity and a preventive activity in the formation of adhesions following anastomosis
US10/139,878 US7202230B2 (en) 1997-07-28 2002-05-07 Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97PD000170A IT1294797B1 (it) 1997-07-28 1997-07-28 Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante

Publications (2)

Publication Number Publication Date
ITPD970170A1 ITPD970170A1 (it) 1999-01-28
IT1294797B1 true IT1294797B1 (it) 1999-04-15

Family

ID=11391877

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97PD000170A IT1294797B1 (it) 1997-07-28 1997-07-28 Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante

Country Status (12)

Country Link
US (1) US7202230B2 (enExample)
EP (1) EP0999859B1 (enExample)
JP (1) JP4417547B2 (enExample)
AT (1) ATE311208T1 (enExample)
AU (1) AU749627B2 (enExample)
CA (1) CA2298733C (enExample)
DE (1) DE69832616T2 (enExample)
DK (1) DK0999859T3 (enExample)
ES (1) ES2253827T3 (enExample)
IL (2) IL134140A0 (enExample)
IT (1) IT1294797B1 (enExample)
WO (1) WO1999004828A2 (enExample)

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JP6062917B2 (ja) 2011-03-23 2017-01-18 ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション 泌尿器科の炎症の治療及び予防の方法
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RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
EP3010419B1 (en) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
BR112016013322B1 (pt) 2013-12-11 2020-07-21 Ferrosan Medical Devices A/S métodos para preparação de uma composição seca e para reconstituir uma composição seca, composição seca, uso de uma composição seca, e, kit
SMT202200083T1 (it) 2014-02-27 2022-03-21 Synartro Ab Coniugati di ialuronano con sostanze farmaceuticamente attive, metodi e composizioni
RU2715235C2 (ru) 2014-10-13 2020-02-26 Ферросан Медикал Дивайсиз А/С Сухая композиция для использования при гемостазе и заживлении ран
CA2970710A1 (en) 2014-12-24 2016-06-30 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
CN107771093B (zh) 2015-07-03 2021-06-15 弗罗桑医疗设备公司 用于混合两种组分和用于在存储条件下保持真空的注射器
KR20180027126A (ko) * 2016-09-06 2018-03-14 (주)한국비엠아이 가교화 히알루론산 유도체 매트릭스가 포함된 지혈 조성물
WO2018053111A1 (en) 2016-09-15 2018-03-22 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
CN112368028A (zh) 2018-05-09 2021-02-12 弗罗桑医疗设备公司 用于制备止血组合物的方法
CN111228653A (zh) 2018-11-13 2020-06-05 格莱科米拉治疗公司 用电离辐射加强癌症治疗的方法
KR101980063B1 (ko) * 2019-01-25 2019-05-17 주식회사 휴메딕스 히알루론산을 포함하는 스펀지형 생분해성 지혈제 조성물
CN113754795B (zh) * 2021-10-19 2023-03-10 澳门大学 磺酸化透明质酸类化合物、其制备方法及其应用
CN116688216A (zh) * 2023-05-26 2023-09-05 北京福爱乐科技发展有限公司 一种生物可降解医用凝胶及其制备方法

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Also Published As

Publication number Publication date
ES2253827T3 (es) 2006-06-01
WO1999004828A3 (en) 1999-06-10
AU9255598A (en) 1999-02-16
DE69832616T2 (de) 2006-08-17
US20030060448A1 (en) 2003-03-27
CA2298733A1 (en) 1999-02-04
ITPD970170A1 (it) 1999-01-28
JP4417547B2 (ja) 2010-02-17
IL134140A (en) 2006-08-20
CA2298733C (en) 2009-09-01
EP0999859B1 (en) 2005-11-30
EP0999859A2 (en) 2000-05-17
HK1028210A1 (en) 2001-02-09
IL134140A0 (en) 2001-04-30
JP2001510713A (ja) 2001-08-07
WO1999004828A2 (en) 1999-02-04
AU749627B2 (en) 2002-06-27
ATE311208T1 (de) 2005-12-15
DK0999859T3 (da) 2006-03-27
US7202230B2 (en) 2007-04-10
DE69832616D1 (de) 2006-01-05

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