DE69832616D1 - Verwendung von hyaluonsäurederivaten zur herstellung von biomaterial - Google Patents

Verwendung von hyaluonsäurederivaten zur herstellung von biomaterial

Info

Publication number
DE69832616D1
DE69832616D1 DE69832616T DE69832616T DE69832616D1 DE 69832616 D1 DE69832616 D1 DE 69832616D1 DE 69832616 T DE69832616 T DE 69832616T DE 69832616 T DE69832616 T DE 69832616T DE 69832616 D1 DE69832616 D1 DE 69832616D1
Authority
DE
Germany
Prior art keywords
biomaterial
manufacture
acid derivatives
hyaluonic
formation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69832616T
Other languages
English (en)
Other versions
DE69832616T2 (de
Inventor
Alberto Rivarossa
Daniele Pressato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anika Therapeutics SRL
Original Assignee
Fidia Advanced Biopolymers SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Advanced Biopolymers SRL filed Critical Fidia Advanced Biopolymers SRL
Application granted granted Critical
Publication of DE69832616D1 publication Critical patent/DE69832616D1/de
Publication of DE69832616T2 publication Critical patent/DE69832616T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69832616T 1997-07-28 1998-07-28 Verwendung von hyaluonsäurederivaten zur herstellung von biomaterial Expired - Lifetime DE69832616T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITPD970170 1997-07-28
IT97PD000170A IT1294797B1 (it) 1997-07-28 1997-07-28 Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante
PCT/EP1998/004716 WO1999004828A2 (en) 1997-07-28 1998-07-28 Use of hyaluronic acid derivatives in the preparation of biomaterials

Publications (2)

Publication Number Publication Date
DE69832616D1 true DE69832616D1 (de) 2006-01-05
DE69832616T2 DE69832616T2 (de) 2006-08-17

Family

ID=11391877

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832616T Expired - Lifetime DE69832616T2 (de) 1997-07-28 1998-07-28 Verwendung von hyaluonsäurederivaten zur herstellung von biomaterial

Country Status (13)

Country Link
US (1) US7202230B2 (de)
EP (1) EP0999859B1 (de)
JP (1) JP4417547B2 (de)
AT (1) ATE311208T1 (de)
AU (1) AU749627B2 (de)
CA (1) CA2298733C (de)
DE (1) DE69832616T2 (de)
DK (1) DK0999859T3 (de)
ES (1) ES2253827T3 (de)
HK (1) HK1028210A1 (de)
IL (2) IL134140A0 (de)
IT (1) IT1294797B1 (de)
WO (1) WO1999004828A2 (de)

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IT1306679B1 (it) * 1999-06-29 2001-10-02 Fidia Advanced Biopolymers Srl Uso dei derivati dell'acido ialuronico per la preparazione dicomposizoni farmaceutiche e biomateriali per la prevenzione della
US7094428B2 (en) 2000-06-16 2006-08-22 The University Of Medicine And Dentistry Of New Jersey Hemostatic compositions, devices and methods
AU2001266926A1 (en) * 2000-06-16 2002-01-02 University Of Medicine And Dentistry Of New Jersey Hemostatic compositions, devices and methods
US6235796B1 (en) * 2000-06-26 2001-05-22 Sarfaraz K. Niazi Use of fluorocarbons for the prevention of surgical adhesions
US20060235114A1 (en) * 2003-07-28 2006-10-19 Teijin Limited Temperature-responsive hydrogel
DE10349722A1 (de) * 2003-10-23 2005-06-16 Beschorner, Katharina, Dr. Zusammensetzung zur Arthrose-/Arthritisbehandlung, insbesondere von Gelenken
EP1786480B1 (de) * 2004-07-09 2016-09-21 Ferrosan Medical Devices A/S Hämostatische zusammensetzung mit hyaluronsäure
ITPD20040245A1 (it) * 2004-10-08 2005-01-08 Fidia Advanced Biopolymers Srl Biomateriali costituiti da acido ialuronico solfatato e gellano utilizzabili nella prevenzione delle adesioni spinali
CA2590783A1 (en) * 2004-12-14 2006-06-22 Fidia Advanced Biopolymers S.R.L. Process for the preparation of two and three dimensional polymer scaffolds
ITPD20040312A1 (it) * 2004-12-15 2005-03-15 Fidia Advanced Biopolymers Srl Protesi e o supporto per la sostituzione, riparazione, rigenerazione del menisco
ITPD20050206A1 (it) * 2005-07-07 2007-01-08 Fidia Advanced Biopolymers Srl Biomateriali in forma di fibra da impiegarsi come dispositivi medici nel trattamento delle ferite e loro processi di produzione
ITMI20051415A1 (it) * 2005-07-22 2007-01-23 Fidia Advanced Biopolymers Srl Biomateriali a base di corbossimetilcellulosa salificata con zinco associata a derivati dell'acido ialuronico da impiegarsi come dispositivi medici con attivita' antimicrobica ed antifungina e loro processo di produzione
JP2009529374A (ja) * 2006-03-07 2009-08-20 アクスル インターナショナル 治療及び癒着防止用生物活性スキャホールド
ITPD20060219A1 (it) 2006-05-31 2007-12-01 Fidia Farmaceutici Composizioni farmaceutiche contenenti acido ialuronico solfatato nel trattamento dell'osteoartrosi
JP5569398B2 (ja) 2008-02-29 2014-08-13 フェッローサン メディカル ディバイス エー／エス 止血および／または創傷治癒を促進するための装置
US8343942B2 (en) 2008-04-04 2013-01-01 University Of Utah Research Foundation Methods for treating interstitial cystitis
AU2009231634B2 (en) * 2008-04-04 2014-05-15 University Of Utah Research Foundation Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof
CA2735173C (en) * 2008-09-02 2017-01-10 Tautona Group Lp Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
TWI458833B (zh) * 2010-05-11 2014-11-01 Univ China Medical 奈米金屬分散液及其製法
WO2012129461A1 (en) 2011-03-23 2012-09-27 University Of Utah Research Foundation Methods for treating or preventing urological inflammation
CA2865349C (en) 2012-03-06 2021-07-06 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
CA2874290C (en) 2012-06-12 2020-02-25 Ferrosan Medical Devices A/S Dry haemostatic composition
CN105358071B (zh) 2013-06-21 2018-07-31 弗罗桑医疗设备公司 真空膨胀的干组合物和用于保留该干组合物的注射器
CA2928963C (en) 2013-12-11 2020-10-27 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
LT3226905T (lt) * 2014-02-27 2022-03-10 Synartro Ab Hialuronano konjugatai su farmaciniu požiūriu aktyviomis medžiagomis, būdai ir kompozicijos
WO2016058612A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
EP3237041B1 (de) 2014-12-24 2020-01-29 Ferrosan Medical Devices A/S Spritze für die enthaltung und die mischung erster und zweiter substanzen
BR112017027695A2 (pt) 2015-07-03 2018-09-04 Ferrosan Medical Devices As seringa para retenção e mistura de primeira e segunda substâncias
KR20180027126A (ko) * 2016-09-06 2018-03-14 (주)한국비엠아이 가교화 히알루론산 유도체 매트릭스가 포함된 지혈 조성물
US11337994B2 (en) 2016-09-15 2022-05-24 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
MX2020011866A (es) 2018-05-09 2021-01-20 Ferrosan Medical Devices As Metodo para preparar una composicion hemostatica.
KR101980063B1 (ko) * 2019-01-25 2019-05-17 주식회사 휴메딕스 히알루론산을 포함하는 스펀지형 생분해성 지혈제 조성물
CN113754795B (zh) * 2021-10-19 2023-03-10 澳门大学 磺酸化透明质酸类化合物、其制备方法及其应用

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US5202431A (en) 1985-07-08 1993-04-13 Fidia, S.P.A. Partial esters of hyaluronic acid
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1203814B (it) 1986-06-30 1989-02-23 Fidia Farmaceutici Esteri dell'acido alginico
IT1198449B (it) 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
US6174999B1 (en) * 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
GB8911177D0 (en) * 1989-05-16 1989-07-05 Vilain Jean Alginate gel pharmaceutical product
EP0518710B1 (de) 1991-02-11 1996-05-22 FIDIA S.p.A. Gellanester
IT1247157B (it) 1991-02-11 1994-12-12 Fidia Spa Canali di guida biodegradabili e bioassorbibili da impiegare per la rigenerazione nervosa.
GB9109367D0 (en) * 1991-05-01 1991-06-26 Merck Sharp & Dohme Surgical dressing
IT1247472B (it) 1991-05-31 1994-12-17 Fidia Spa Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
IT1254704B (it) 1991-12-18 1995-10-09 Mini Ricerca Scient Tecnolog Tessuto non tessuto essenzialmente costituito da derivati dell'acido ialuronico
IT1264322B (it) 1992-07-30 1996-09-23 Lanfranco Callegaro Esteri di gellano autoreticolato, procedimento di preparazione e loro applicazioni farmaceutiche e biomedico-sanitarie
IT1259141B (it) 1992-08-03 1996-03-11 Fidia Spa Canali di guida biodegradabili e bioriassorbibili da impiegare per la riparazione tissutale come adiuvante in interventi chirurgici
ITPD940054A1 (it) * 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
FR2723847A1 (fr) * 1994-08-29 1996-03-01 Debiopharm Sa Compositions antithrombotiques et non hemorragiques a base d'heparine, procede pour leur preparation et applications therapeutiques.
IT1281877B1 (it) * 1995-05-10 1998-03-03 Fidia Advanced Biopolymers Srl Sali di metalli pesanti di succinil derivati dell'acido ialuronico e loro impiego come potenziali agenti terapeutici
GB9514361D0 (en) * 1995-07-13 1995-09-13 Bristol Myers Squibb Co A film for topical use in the treatment of wounds
IL123500A (en) * 1995-08-29 2003-06-24 Fidia Advanced Biopolymers Srl Composite biomaterials for preventing post-surgical adhesions of tissues
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Also Published As

Publication number Publication date
CA2298733A1 (en) 1999-02-04
DE69832616T2 (de) 2006-08-17
ITPD970170A1 (it) 1999-01-28
WO1999004828A2 (en) 1999-02-04
ES2253827T3 (es) 2006-06-01
JP2001510713A (ja) 2001-08-07
AU9255598A (en) 1999-02-16
WO1999004828A3 (en) 1999-06-10
AU749627B2 (en) 2002-06-27
IT1294797B1 (it) 1999-04-15
HK1028210A1 (en) 2001-02-09
JP4417547B2 (ja) 2010-02-17
EP0999859A2 (de) 2000-05-17
IL134140A0 (en) 2001-04-30
DK0999859T3 (da) 2006-03-27
US7202230B2 (en) 2007-04-10
ATE311208T1 (de) 2005-12-15
EP0999859B1 (de) 2005-11-30
US20030060448A1 (en) 2003-03-27
IL134140A (en) 2006-08-20
CA2298733C (en) 2009-09-01

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: FIDIA ADVANCED BIOPOLYMERS, S.R.L., ABANO TERME, (

8364 No opposition during term of opposition