IT1271438B - Agente per sopprimere e interrompere la reazione di mailard - Google Patents

Agente per sopprimere e interrompere la reazione di mailard

Info

Publication number
IT1271438B
IT1271438B ITMI930491A ITMI930491A IT1271438B IT 1271438 B IT1271438 B IT 1271438B IT MI930491 A ITMI930491 A IT MI930491A IT MI930491 A ITMI930491 A IT MI930491A IT 1271438 B IT1271438 B IT 1271438B
Authority
IT
Italy
Prior art keywords
agent
group
interrupt
mailard reaction
suppress
Prior art date
Application number
ITMI930491A
Other languages
English (en)
Inventor
Norihiro Kakimoto
Nakamura Kunie
Original Assignee
Asai Germanium Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asai Germanium Res Inst filed Critical Asai Germanium Res Inst
Publication of ITMI930491A0 publication Critical patent/ITMI930491A0/it
Publication of ITMI930491A1 publication Critical patent/ITMI930491A1/it
Application granted granted Critical
Publication of IT1271438B publication Critical patent/IT1271438B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/30—Germanium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invenzione mette a disposizione un agente per sopprimere oppure interrompere la reazione di Mailard, il quale comprende come componente attivo un composto organico del germanio rappresentato dalla formula (1): (FORMULA 1) in cui i simboli da R1 fino a R3 possono essere uguali oppure differenti e ciascuno di essi rappresenta un atomo di idrogeno, un gruppo alchile inferiore, oppure un gruppo fenile sostituito oppure non sostituito; e X rappresenta un gruppo ossidrile, un gruppo O-inferiore-alchile, un gruppo amminico oppure un sale rappresentato da OY (Y è un metallo oppure un composto contenente un gruppo basico). Detto agente può sopprimere oppure interrompere efficacemente la reazione di Mailard e ha un elevato grado di sicurezza anche quando viene somministrato per un periodo di tempo prolungato.
ITMI930491A 1992-03-16 1993-03-15 Agente per sopprimere e interrompere la reazione di mailard IT1271438B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4091685A JPH05255130A (ja) 1992-03-16 1992-03-16 メイラード反応抑制改善剤

Publications (3)

Publication Number Publication Date
ITMI930491A0 ITMI930491A0 (it) 1993-03-15
ITMI930491A1 ITMI930491A1 (it) 1994-09-15
IT1271438B true IT1271438B (it) 1997-05-28

Family

ID=14033361

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI930491A IT1271438B (it) 1992-03-16 1993-03-15 Agente per sopprimere e interrompere la reazione di mailard

Country Status (11)

Country Link
US (1) US5352815A (it)
JP (1) JPH05255130A (it)
KR (1) KR100245571B1 (it)
AU (1) AU659589B2 (it)
CA (1) CA2091651C (it)
CH (1) CH685876A5 (it)
DE (1) DE4308374C2 (it)
FR (1) FR2689763B1 (it)
GB (1) GB2265547B (it)
IT (1) IT1271438B (it)
TW (1) TW278036B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1143432A (ja) * 1997-07-25 1999-02-16 Biremo Sci:Kk 脳の老化抑制及び治療剤
CN1150034C (zh) 1998-08-24 2004-05-19 黑川清 羰基压力改善剂和腹膜透析液

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1365997A (en) * 1972-05-25 1974-09-04 Asai K Medicament comprising an organo germanium sesquioxide compound
JPS5632485A (en) * 1979-08-24 1981-04-01 Pola Chem Ind Inc Preparation of organogermanium compound
DE3212817A1 (de) * 1982-04-06 1983-10-13 Sanum-Kehlbeck GmbH & Co KG, 2812 Hoya Pharmazeutisch wirksame organische germaniumverbindungen und verfahren zu deren herstellung
JPS601317B2 (ja) * 1982-08-23 1985-01-14 紀博 柿本 親水性及び親油性を併せ有する有機ゲルマニウム化合物
JPS6041472A (ja) * 1983-08-16 1985-03-05 Refuorumu Syst Kk 美容・健康飲料
JPS60226592A (ja) * 1984-04-25 1985-11-11 Asai Gerumaniumu Kenkyusho:Kk 抗酸化剤
JPS61145115A (ja) * 1984-12-18 1986-07-02 Asai Gerumaniumu Kenkyusho:Kk 塵肺症患者用風邪症候群予防剤
JPS63107920A (ja) * 1986-06-18 1988-05-12 Asai Gerumaniumu Kenkyusho:Kk 骨芽細胞活性化剤
US4973553A (en) * 1987-09-09 1990-11-27 Asai Germanium Research Institute Salt or organogermanium compound and medicine containing the same
CA1314210C (en) * 1987-10-29 1993-03-09 Norihiro Kakimoto Agent for improving reduced functions of organs caused by inhibited blood circulation
JP2698870B2 (ja) * 1987-10-29 1998-01-19 株式会社浅井ゲルマニウム研究所 シクロスポリンの投与による腎毒性の軽減剤
JPH01149723A (ja) * 1987-12-07 1989-06-12 Asai Gerumaniumu Kenkyusho:Kk 骨芽細胞活性化剤
JP2652556B2 (ja) * 1988-08-29 1997-09-10 株式会社浅井ゲルマニウム研究所 有機ゲルマニウム化合物及びその製造方法
EP0404062A3 (en) * 1989-06-20 1991-09-25 Sanwa Kagaku Kenkyusho Co., Ltd. Organogermanium compound, process for preparation of same as well as use thereof
AU635045B2 (en) * 1989-07-20 1993-03-11 Asai Germanium Research Institute Co., Ltd Agent for preventing and treating opacity of lens
JPH03251526A (ja) * 1990-02-28 1991-11-11 Sanwa Kagaku Kenkyusho Co Ltd 糖尿病依存型自己免疫疾患治療、予防用薬剤

Also Published As

Publication number Publication date
FR2689763A1 (fr) 1993-10-15
GB2265547A (en) 1993-10-06
GB9305309D0 (en) 1993-05-05
TW278036B (it) 1996-06-11
CA2091651C (en) 2003-09-23
JPH05255130A (ja) 1993-10-05
US5352815A (en) 1994-10-04
DE4308374C2 (de) 2002-01-03
GB2265547B (en) 1996-07-31
KR100245571B1 (ko) 2000-03-02
CA2091651A1 (en) 1993-09-17
FR2689763B1 (fr) 1995-04-28
CH685876A5 (fr) 1995-10-31
KR930019210A (ko) 1993-10-18
ITMI930491A0 (it) 1993-03-15
ITMI930491A1 (it) 1994-09-15
AU3511893A (en) 1993-09-23
DE4308374A1 (de) 1993-10-07
AU659589B2 (en) 1995-05-18

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970429