IT1199203B - Derivati del carbapenem fluoroalchilati,loro preparazione e loro impiego come medicamenti - Google Patents
Derivati del carbapenem fluoroalchilati,loro preparazione e loro impiego come medicamentiInfo
- Publication number
- IT1199203B IT1199203B IT48934/84A IT4893484A IT1199203B IT 1199203 B IT1199203 B IT 1199203B IT 48934/84 A IT48934/84 A IT 48934/84A IT 4893484 A IT4893484 A IT 4893484A IT 1199203 B IT1199203 B IT 1199203B
- Authority
- IT
- Italy
- Prior art keywords
- fluoroalkylated
- medications
- preparation
- carbapenem derivatives
- carbapenem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH5363/83A CH660736A5 (de) | 1983-10-03 | 1983-10-03 | Carbapenemderivate. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8448934A0 IT8448934A0 (it) | 1984-10-02 |
| IT8448934A1 IT8448934A1 (it) | 1986-04-02 |
| IT1199203B true IT1199203B (it) | 1988-12-30 |
Family
ID=4292307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48934/84A IT1199203B (it) | 1983-10-03 | 1984-10-02 | Derivati del carbapenem fluoroalchilati,loro preparazione e loro impiego come medicamenti |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4720491A (it) |
| JP (2) | JPS60105676A (it) |
| KR (1) | KR910009290B1 (it) |
| AT (1) | AT386204B (it) |
| AU (1) | AU3376084A (it) |
| BE (1) | BE900718A (it) |
| CA (1) | CA1241656A (it) |
| CH (2) | CH662117A5 (it) |
| DE (1) | DE3434504A1 (it) |
| DK (1) | DK470684A (it) |
| ES (1) | ES8706680A1 (it) |
| FI (1) | FI843847L (it) |
| FR (1) | FR2552763B1 (it) |
| GB (1) | GB2147298B (it) |
| GR (1) | GR80515B (it) |
| HU (1) | HUT36478A (it) |
| IL (1) | IL73127A0 (it) |
| IT (1) | IT1199203B (it) |
| LU (1) | LU85570A1 (it) |
| NL (1) | NL8402936A (it) |
| PL (1) | PL249834A1 (it) |
| PT (1) | PT79293B (it) |
| SE (1) | SE462493B (it) |
| ZA (1) | ZA847781B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60202886A (ja) * | 1984-03-27 | 1985-10-14 | Sankyo Co Ltd | １―置換カルバペネム―３―カルボン酸誘導体 |
| EP0234484B1 (en) * | 1986-02-19 | 1993-10-20 | Sanraku Incorporated | Novel azetidinone derivatives |
| EP0464900A3 (en) | 1990-06-26 | 1992-07-22 | Merck & Co. Inc. | 2-biphenyl-carbapenems |
| CA2052730A1 (en) | 1990-10-11 | 1992-04-12 | Frank P. Dininno | 2-(substituted-dibenzofuranyl and dibenzothienyl) carbapenem antibacterial agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4312871A (en) * | 1979-12-03 | 1982-01-26 | Merck & Co., Inc. | 6-, 1- And 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
| PT73791B (en) * | 1980-10-17 | 1983-10-14 | Merck & Co Inc | Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids |
| ES514240A0 (es) * | 1981-08-03 | 1984-04-16 | Merck & Co Inc | Un procedimiento para la prepracion de nuevos derivados de acidos 2-carbamimidoil-1-,carbadestiapen-2-en-3-carboxilados. |
| FI832619A (fi) * | 1982-07-26 | 1984-01-27 | Sandoz Ag | Fluoralkylerade karbapenemderivat |
-
1983
- 1983-10-03 CH CH1457/86A patent/CH662117A5/de not_active IP Right Cessation
- 1983-10-03 CH CH5363/83A patent/CH660736A5/de not_active IP Right Cessation
-
1984
- 1984-09-19 HU HU843532A patent/HUT36478A/hu unknown
- 1984-09-20 DE DE19843434504 patent/DE3434504A1/de not_active Ceased
- 1984-09-26 NL NL8402936A patent/NL8402936A/xx not_active Application Discontinuation
- 1984-09-30 IL IL73127A patent/IL73127A0/xx unknown
- 1984-10-01 DK DK470684A patent/DK470684A/da not_active Application Discontinuation
- 1984-10-01 BE BE1/11108A patent/BE900718A/fr not_active IP Right Cessation
- 1984-10-01 GB GB08424708A patent/GB2147298B/en not_active Expired
- 1984-10-01 FR FR8415143A patent/FR2552763B1/fr not_active Expired
- 1984-10-01 PT PT79293A patent/PT79293B/pt unknown
- 1984-10-01 SE SE8404906A patent/SE462493B/sv not_active IP Right Cessation
- 1984-10-01 FI FI843847A patent/FI843847L/fi not_active Application Discontinuation
- 1984-10-01 GR GR80515A patent/GR80515B/el unknown
- 1984-10-02 KR KR1019840006145A patent/KR910009290B1/ko active IP Right Grant
- 1984-10-02 AU AU33760/84A patent/AU3376084A/en not_active Abandoned
- 1984-10-02 JP JP59206953A patent/JPS60105676A/ja active Granted
- 1984-10-02 AT AT0311584A patent/AT386204B/de not_active IP Right Cessation
- 1984-10-02 PL PL24983484A patent/PL249834A1/xx unknown
- 1984-10-02 IT IT48934/84A patent/IT1199203B/it active
- 1984-10-02 ES ES536443A patent/ES8706680A1/es not_active Expired
- 1984-10-02 LU LU85570A patent/LU85570A1/fr unknown
- 1984-10-03 ZA ZA847781A patent/ZA847781B/xx unknown
- 1984-10-03 CA CA000464654A patent/CA1241656A/en not_active Expired
-
1985
- 1985-10-30 US US06/793,017 patent/US4720491A/en not_active Expired - Fee Related
-
1991
- 1991-10-02 JP JP3255239A patent/JPH0670059B2/ja not_active Expired - Lifetime
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