IT1190351B - Procedimento stereocontrollato per la produzione di acetossiazetidinone - Google Patents

Procedimento stereocontrollato per la produzione di acetossiazetidinone

Info

Publication number
IT1190351B
IT1190351B IT20246/85A IT2024685A IT1190351B IT 1190351 B IT1190351 B IT 1190351B IT 20246/85 A IT20246/85 A IT 20246/85A IT 2024685 A IT2024685 A IT 2024685A IT 1190351 B IT1190351 B IT 1190351B
Authority
IT
Italy
Prior art keywords
acetoxiazetidinone
stereo
production
controlled procedure
procedure
Prior art date
Application number
IT20246/85A
Other languages
English (en)
Other versions
IT8520246A0 (it
Inventor
Alain Martel
Jean Paul Daris
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8520246A0 publication Critical patent/IT8520246A0/it
Application granted granted Critical
Publication of IT1190351B publication Critical patent/IT1190351B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IT20246/85A 1984-04-06 1985-04-05 Procedimento stereocontrollato per la produzione di acetossiazetidinone IT1190351B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/597,765 US4596677A (en) 1984-04-06 1984-04-06 Anhydropenicillin intermediates

Publications (2)

Publication Number Publication Date
IT8520246A0 IT8520246A0 (it) 1985-04-05
IT1190351B true IT1190351B (it) 1988-02-16

Family

ID=24392838

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20246/85A IT1190351B (it) 1984-04-06 1985-04-05 Procedimento stereocontrollato per la produzione di acetossiazetidinone

Country Status (36)

Country Link
US (2) US4596677A (it)
JP (2) JPS6117586A (it)
KR (1) KR920006919B1 (it)
AR (1) AR241139A1 (it)
AT (1) AT388556B (it)
AU (1) AU580043B2 (it)
BE (1) BE902133A (it)
CA (1) CA1261318A (it)
CH (1) CH665420A5 (it)
CS (1) CS253724B2 (it)
CY (1) CY1572A (it)
DD (1) DD232132A5 (it)
DE (1) DE3512250A1 (it)
DK (1) DK156085A (it)
ES (1) ES8702422A1 (it)
FI (1) FI86852C (it)
FR (1) FR2562541B1 (it)
GB (1) GB2156814B (it)
GR (1) GR850879B (it)
HK (1) HK106090A (it)
HU (2) HU194250B (it)
IE (1) IE58409B1 (it)
IL (1) IL74799A (it)
IT (1) IT1190351B (it)
LU (1) LU85841A1 (it)
NL (1) NL8500986A (it)
NO (2) NO164902C (it)
NZ (1) NZ211457A (it)
OA (1) OA07984A (it)
PT (1) PT80235B (it)
SE (3) SE466201B (it)
SG (1) SG91090G (it)
SU (2) SU1400504A3 (it)
YU (3) YU45918B (it)
ZA (1) ZA852237B (it)
ZW (1) ZW5585A1 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1256444A (en) * 1986-04-30 1989-06-27 Kazunori Kan Process for preparing 4-acetoxy-3- hydroxyethylazetidin-2-one derivatives
US5075438A (en) * 1986-07-21 1991-12-24 Schering Corporation Synthesis of azetidinones
US4876338A (en) * 1986-07-21 1989-10-24 Schering Corporation Synthesis of azetidinones using CuCl
US5053502A (en) * 1986-07-21 1991-10-01 Schering Corporation Anhydro penicillin derivatives
US4948885A (en) * 1986-07-21 1990-08-14 Schering-Plough Corp. Synthesis of azetidinones
US4767853A (en) * 1986-07-21 1988-08-30 Schering Corporation Synthesis of 1-(allyloxycarbonyl)-methyl-3-(hydroxyethyl)-4-beta-naphthoxythiocarbonylthio-2-azetidinones and hydroxy protected analogs thereof
EP0290385B1 (de) * 1987-05-04 1992-10-21 Ciba-Geigy Ag Neues Verfahren zur Herstellung von 4-Acyloxy-3-hydroxyethyl-azetidinonen
US5274188A (en) * 1987-05-04 1993-12-28 Ciba-Geigy Corporation Process for the manufacture of 4-acyloxy-3-hydroxyethyl-azetidinones
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems
WO2005023821A1 (ja) * 2003-09-03 2005-03-17 Otsuka Chemical Co., Ltd. ペニシラン酸化合物の製造方法
JP5300713B2 (ja) * 2007-03-09 2013-09-25 大塚化学株式会社 6−ヒドロキシエチルペナム化合物の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3311638A (en) * 1961-08-16 1967-03-28 Bristol Myers Co Anhydropenicillins
US3950352A (en) * 1972-04-10 1976-04-13 Queen's University 2,2-Dimethyl-3R-carboxy-6S-phenyl(or phenoxy)acetamido-1-oxa-4-aza-5R-bicyclo[3,2,0]heptan-7-one and processes for their production
SE449103B (sv) * 1979-03-05 1987-04-06 Pfizer Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
US4356120A (en) * 1979-07-23 1982-10-26 Merck & Co., Inc. 3-(1-Hydroxyethyl)-4-(but-2-ene)-azetidin-2-one and derivatives
US4468351A (en) * 1983-06-06 1984-08-28 Pfizer Inc. Process for debromination of dibromopenicillanic acid and derivatives

Also Published As

Publication number Publication date
DK156085A (da) 1985-10-07
AR241139A2 (es) 1991-11-29
FR2562541A1 (fr) 1985-10-11
AU4086485A (en) 1985-10-10
JPH032157B2 (it) 1991-01-14
IL74799A (en) 1988-11-15
FI851324A0 (fi) 1985-04-02
IE850867L (en) 1985-10-06
HUT38349A (en) 1986-05-28
US4596677A (en) 1986-06-24
ES8702422A1 (es) 1987-01-01
YU134487A (en) 1988-02-29
GB2156814A (en) 1985-10-16
HUT40442A (en) 1986-12-28
YU57185A (en) 1988-02-29
ATA104285A (de) 1988-12-15
ES541866A0 (es) 1987-01-01
HK106090A (en) 1990-12-21
JPS6117586A (ja) 1986-01-25
FI86852C (fi) 1992-10-26
NO851310L (no) 1985-10-07
SE8501679D0 (sv) 1985-04-03
KR850007585A (ko) 1985-12-07
SE9000791D0 (sv) 1990-03-06
FI851324L (fi) 1985-10-07
DD232132A5 (de) 1986-01-15
DK156085D0 (da) 1985-04-03
NO166132B (no) 1991-02-25
YU45918B (sh) 1992-09-07
AR241139A1 (es) 1991-11-29
SG91090G (en) 1991-01-18
DE3512250A1 (de) 1985-10-17
YU46059B (sh) 1992-12-21
JPH0312072B2 (it) 1991-02-19
BE902133A (fr) 1985-10-07
HU194250B (en) 1988-01-28
SE8501679L (sv) 1985-10-07
GB2156814B (en) 1987-12-31
CS253724B2 (en) 1987-12-17
ZW5585A1 (en) 1985-11-06
CA1261318A (en) 1989-09-26
SE9000791L (sv) 1991-09-07
SE466201B (sv) 1992-01-13
KR920006919B1 (ko) 1992-08-22
SU1435154A3 (ru) 1988-10-30
YU134587A (en) 1988-02-29
NL8500986A (nl) 1985-11-01
IL74799A0 (en) 1985-07-31
IT8520246A0 (it) 1985-04-05
NO166132C (no) 1991-06-05
NO164902C (no) 1990-11-28
FR2562541B1 (fr) 1986-12-26
NO164902B (no) 1990-08-20
US4639335A (en) 1987-01-27
FI86852B (fi) 1992-07-15
SE9000790L (sv) 1991-09-07
IE58409B1 (en) 1993-09-22
AU580043B2 (en) 1988-12-22
SE9000790D0 (sv) 1990-03-06
HU193959B (en) 1987-12-28
CH665420A5 (de) 1988-05-13
JPS61171485A (ja) 1986-08-02
PT80235A (en) 1985-05-01
NZ211457A (en) 1989-03-29
GR850879B (it) 1985-11-25
GB8508847D0 (en) 1985-05-09
AT388556B (de) 1989-07-25
PT80235B (pt) 1987-10-20
NO860326L (no) 1985-10-07
OA07984A (fr) 1987-01-31
CY1572A (en) 1991-12-20
YU46060B (sh) 1992-12-21
SU1400504A3 (ru) 1988-05-30
ZA852237B (en) 1985-11-27
LU85841A1 (fr) 1985-12-16

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