IT1167123B - Benzoazacicloalchilspiro-imidazolidine,procedimento per prepararle e composizioni farmaceutiche che le contengono - Google Patents
Benzoazacicloalchilspiro-imidazolidine,procedimento per prepararle e composizioni farmaceutiche che le contengonoInfo
- Publication number
- IT1167123B IT1167123B IT48155/83A IT4815583A IT1167123B IT 1167123 B IT1167123 B IT 1167123B IT 48155/83 A IT48155/83 A IT 48155/83A IT 4815583 A IT4815583 A IT 4815583A IT 1167123 B IT1167123 B IT 1167123B
- Authority
- IT
- Italy
- Prior art keywords
- benzoazacycloalkylspyro
- imidazolidine
- prepare
- procedure
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8207203A FR2525603A1 (fr) | 1982-04-27 | 1982-04-27 | Benzoazacycloalkyl-spiro-imidazolinines, leur preparation et leur application en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8348155A0 IT8348155A0 (it) | 1983-04-26 |
| IT1167123B true IT1167123B (it) | 1987-05-13 |
Family
ID=9273425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48155/83A IT1167123B (it) | 1982-04-27 | 1983-04-26 | Benzoazacicloalchilspiro-imidazolidine,procedimento per prepararle e composizioni farmaceutiche che le contengono |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5910584A (no) |
| KR (1) | KR840004428A (no) |
| AT (1) | ATA125383A (no) |
| AU (1) | AU1395383A (no) |
| BE (1) | BE896572A (no) |
| DD (1) | DD209833A5 (no) |
| DE (1) | DE3315106A1 (no) |
| DK (1) | DK183583A (no) |
| ES (1) | ES521895A0 (no) |
| FR (1) | FR2525603A1 (no) |
| GB (1) | GB2133401B (no) |
| GR (1) | GR78481B (no) |
| IL (1) | IL68497A0 (no) |
| IT (1) | IT1167123B (no) |
| LU (1) | LU84770A1 (no) |
| MA (1) | MA19783A1 (no) |
| NL (1) | NL8301476A (no) |
| NO (1) | NO831473L (no) |
| OA (1) | OA07412A (no) |
| PT (1) | PT76595B (no) |
| SE (1) | SE8302347L (no) |
| ZA (1) | ZA832927B (no) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU617541B2 (en) * | 1988-10-20 | 1991-11-28 | Wyeth | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
| US4927831A (en) * | 1988-10-20 | 1990-05-22 | American Home Products | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
| EA016558B1 (ru) | 2003-06-17 | 2012-05-30 | Арена Фармасьютикалз, Инк. | Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором |
| MXPA05013364A (es) | 2003-06-17 | 2006-03-17 | Arena Pharm Inc | Procedimiento para preparar 3-benzazepinas. |
| JP5270167B2 (ja) | 2004-12-21 | 2013-08-21 | アリーナ ファーマシューティカルズ， インコーポレイテッド | （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形 |
| SG158168A1 (en) | 2004-12-23 | 2010-01-29 | Arena Pharm Inc | 5ht2c receptor modulator compositions and methods of use |
| WO2007120517A2 (en) | 2006-04-03 | 2007-10-25 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto |
| JP5404414B2 (ja) | 2006-12-05 | 2014-01-29 | アリーナ ファーマシューティカルズ， インコーポレイテッド | （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピンおよびその中間体を調製するための方法 |
| WO2009111004A1 (en) | 2008-03-04 | 2009-09-11 | Arena Pharmaceuticals, Inc. | Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine |
| WO2010148207A2 (en) | 2009-06-18 | 2010-12-23 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| US9045431B2 (en) | 2010-06-02 | 2015-06-02 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-HT2C receptor agonists |
| WO2012030938A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Salts of lorcaserin with optically active acids |
| KR101913442B1 (ko) | 2010-09-01 | 2018-10-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 체중 관리에 유용한 5-ｈｔ2ｃ 작동제의 변형-방출 투여 형태 |
| WO2012030939A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Administration of lorcaserin to individuals with renal impairment |
| MX2013002421A (es) | 2010-09-01 | 2013-05-17 | Arena Pharm Inc | Sales no hidroscopicas de agonistas de 5-ht2c. |
| AU2012392187B2 (en) | 2012-10-09 | 2018-07-12 | Arena Pharmaceuticals, Inc. | Method of weight management |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4209630A (en) * | 1976-10-18 | 1980-06-24 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
-
1982
- 1982-04-27 FR FR8207203A patent/FR2525603A1/fr active Granted
-
1983
- 1983-04-08 AT AT0125383A patent/ATA125383A/de not_active IP Right Cessation
- 1983-04-25 DD DD83250187A patent/DD209833A5/de unknown
- 1983-04-25 LU LU84770A patent/LU84770A1/fr unknown
- 1983-04-26 IT IT48155/83A patent/IT1167123B/it active
- 1983-04-26 AU AU13953/83A patent/AU1395383A/en not_active Abandoned
- 1983-04-26 SE SE8302347A patent/SE8302347L/xx not_active Application Discontinuation
- 1983-04-26 BE BE0/210633A patent/BE896572A/fr not_active IP Right Cessation
- 1983-04-26 GR GR71214A patent/GR78481B/el unknown
- 1983-04-26 PT PT76595A patent/PT76595B/pt unknown
- 1983-04-26 DK DK183583A patent/DK183583A/da not_active Application Discontinuation
- 1983-04-26 IL IL68497A patent/IL68497A0/xx unknown
- 1983-04-26 JP JP58073687A patent/JPS5910584A/ja active Pending
- 1983-04-26 KR KR1019830001753A patent/KR840004428A/ko not_active Application Discontinuation
- 1983-04-26 NL NL8301476A patent/NL8301476A/nl not_active Application Discontinuation
- 1983-04-26 ZA ZA832927A patent/ZA832927B/xx unknown
- 1983-04-26 NO NO831473A patent/NO831473L/no unknown
- 1983-04-27 ES ES521895A patent/ES521895A0/es active Granted
- 1983-04-27 OA OA57984A patent/OA07412A/xx unknown
- 1983-04-27 GB GB08311508A patent/GB2133401B/en not_active Expired
- 1983-04-27 DE DE19833315106 patent/DE3315106A1/de not_active Withdrawn
- 1983-04-27 MA MA20003A patent/MA19783A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5910584A (ja) | 1984-01-20 |
| ATA125383A (de) | 1986-05-15 |
| DD209833A5 (de) | 1984-05-23 |
| MA19783A1 (fr) | 1983-12-31 |
| AU1395383A (en) | 1983-11-03 |
| DK183583D0 (da) | 1983-04-26 |
| DK183583A (da) | 1983-10-28 |
| IL68497A0 (en) | 1983-07-31 |
| FR2525603B1 (no) | 1984-09-14 |
| GB2133401B (en) | 1985-10-23 |
| SE8302347L (sv) | 1983-10-28 |
| ES8405796A1 (es) | 1984-06-16 |
| ZA832927B (en) | 1984-06-27 |
| KR840004428A (ko) | 1984-10-15 |
| LU84770A1 (fr) | 1984-11-28 |
| GB2133401A (en) | 1984-07-25 |
| PT76595A (fr) | 1983-05-01 |
| SE8302347D0 (sv) | 1983-04-26 |
| GB8311508D0 (en) | 1983-06-02 |
| NO831473L (no) | 1983-10-28 |
| IT8348155A0 (it) | 1983-04-26 |
| NL8301476A (nl) | 1983-11-16 |
| GR78481B (no) | 1984-09-27 |
| ES521895A0 (es) | 1984-06-16 |
| BE896572A (fr) | 1983-10-26 |
| FR2525603A1 (fr) | 1983-10-28 |
| DE3315106A1 (de) | 1983-11-03 |
| OA07412A (fr) | 1984-11-30 |
| PT76595B (fr) | 1986-01-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT1170387B (it) | Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono | |
| IT1179367B (it) | Composizioni farmaceutiche contenenti ranitidina e procedimento per prepararle | |
| BR1100036A (pt) | Composto e composição farmacêutica | |
| DK68392A (da) | Farmaceutisk praeparat indeholdende cefuroximaxetil | |
| IL67826A0 (en) | Pyrazolooxazines,pyrazolothiazines and pyrazoloquinolines,their preparation and pharmaceutical compositions containing them | |
| IT1211936B (it) | Chetoni triciclici,procedimento per prepararli e composizioni farmaceutiche che li contengono | |
| IL70365A0 (en) | Substituted tetrapeptides,their manufacture and pharmaceutical compositions containing them | |
| IT1167123B (it) | Benzoazacicloalchilspiro-imidazolidine,procedimento per prepararle e composizioni farmaceutiche che le contengono | |
| IT1162879B (it) | Composizioni farmaceutiche | |
| IT1182061B (it) | Derivati di amminofenolo, procedimento per prepararli e composizione farmaceutica che li contiene | |
| IT1180748B (it) | Eteri amminociclopentilici,procedimento per prepararli e composizione farmaceutica che li comprende | |
| IL68586A0 (en) | 4-aryl-4-piperidinecarbinols,their preparation and pharmaceutical compositions containing them | |
| IT1177580B (it) | Composizione farmaceutica contenente rifampicina e procedimento per prepararla | |
| IL68699A (en) | 3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them | |
| IT1109281B (it) | N-benzil-antracicline procedimento per prepararle e composizioni farmaceutiche che le contengono | |
| IT1170361B (it) | Cianoguanidine, procedimento per ottenerle e composizioni farmaceutiche che le contengono | |
| IT1200163B (it) | 8alfa-acilamminoergoline, loro preparazione e composizioni farmaceutiche che le contengono | |
| IT1162430B (it) | Antibiotico bn-183b,procedimento per produrlo e composizioni farmaceutiche che lo contengono | |
| IT1177981B (it) | Amminociclopentani, composizioni farmaceutiche che li contengono e procedimento per la loro preparazione | |
| IT1171389B (it) | Composti amminosteroidi composizioni farmaceutiche che li contengono e procentimento per prepararli | |
| IT1145371B (it) | Alcossi-acil carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono | |
| IT1197654B (it) | Fenilossialchil-piperidine,procedimenti per prepararle e composizioni farmaceutiche che le contengono | |
| IT1212876B (it) | Antibiotici cefalosporinici,procedimento per prepararli e composizioni farmaceutiche che li contengono | |
| IT1172268B (it) | Piperidinoguanidine sostituite,procedimento per la loro preparazione e composizioni farmaceutiche che le contengono | |
| IT8348192A0 (it) | Carbossamidosuanidine, procedimento per ottenerle e composizioni farmaceutiche che le contengono |