IT1083903B - Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche - Google Patents

Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche

Info

Publication number
IT1083903B
IT1083903B IT26608/77A IT2660877A IT1083903B IT 1083903 B IT1083903 B IT 1083903B IT 26608/77 A IT26608/77 A IT 26608/77A IT 2660877 A IT2660877 A IT 2660877A IT 1083903 B IT1083903 B IT 1083903B
Authority
IT
Italy
Prior art keywords
heparinosimil
eteropolisaccaridi
oligo
activities
procedure
Prior art date
Application number
IT26608/77A
Other languages
English (en)
Italian (it)
Original Assignee
Lobo Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11219874&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1083903(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lobo Srl filed Critical Lobo Srl
Priority to IT26608/77A priority Critical patent/IT1083903B/it
Priority to GB7831825A priority patent/GB2002406B/en
Priority to CH823778A priority patent/CH642979A5/it
Priority to DE19782833898 priority patent/DE2833898A1/de
Priority to AU38738/78A priority patent/AU3873878A/en
Priority to DK349678A priority patent/DK159278B/da
Priority to FR7823499A priority patent/FR2400037A1/fr
Priority to JP9627778A priority patent/JPS5430277A/ja
Priority to ES472934A priority patent/ES472934A1/es
Publication of IT1083903B publication Critical patent/IT1083903B/it
Application granted granted Critical
Priority to US06/816,838 priority patent/US4757057A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IT26608/77A 1977-08-09 1977-08-09 Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche IT1083903B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT26608/77A IT1083903B (it) 1977-08-09 1977-08-09 Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche
GB7831825A GB2002406B (en) 1977-08-09 1978-08-01 Oligoheteropolysaccharides having a heparin-like activity method for their preparation and pharmaceutical compositions based thereon
CH823778A CH642979A5 (it) 1977-08-09 1978-08-02 Oligo-eteropolisaccaridi con attivita eparinosimili, procedimento per il loro ottenimento e relative composizioni terapeutiche.
DE19782833898 DE2833898A1 (de) 1977-08-09 1978-08-02 Oligo-heteropolysaccharide mit heparino-aehnlichen wirkungen, verfahren zu deren herstellung und entsprechende therapeutische praeparate
AU38738/78A AU3873878A (en) 1977-08-09 1978-08-08 Oligo-heteropolysaccharides having a heparin-like activity
DK349678A DK159278B (da) 1977-08-09 1978-08-08 Fremgangsmaade til fremstilling af depolymeriseret heparin
FR7823499A FR2400037A1 (fr) 1977-08-09 1978-08-09 Oligo-heteropolysaccharides a activite semblable a celle de l'heparine, procede pour leur preparation et compositions therapeutiques correspondantes
JP9627778A JPS5430277A (en) 1977-08-09 1978-08-09 Oligooheteropolysucrides of heparinnlike activity*preparation thereof and composition based thereon
ES472934A ES472934A1 (es) 1977-08-09 1978-08-09 Procedimiento para la obtencion de oligiheteropolizacaridos,aplicables especialmente al tratamiento de la trombosis
US06/816,838 US4757057A (en) 1977-08-09 1986-01-07 Oligo-heteropolysaccharides having a heparin-like activity method for their preparation and pharmaceutical compositions based thereon

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26608/77A IT1083903B (it) 1977-08-09 1977-08-09 Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche

Publications (1)

Publication Number Publication Date
IT1083903B true IT1083903B (it) 1985-05-25

Family

ID=11219874

Family Applications (1)

Application Number Title Priority Date Filing Date
IT26608/77A IT1083903B (it) 1977-08-09 1977-08-09 Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche

Country Status (10)

Country Link
US (1) US4757057A (cg-RX-API-DMAC10.html)
JP (1) JPS5430277A (cg-RX-API-DMAC10.html)
AU (1) AU3873878A (cg-RX-API-DMAC10.html)
CH (1) CH642979A5 (cg-RX-API-DMAC10.html)
DE (1) DE2833898A1 (cg-RX-API-DMAC10.html)
DK (1) DK159278B (cg-RX-API-DMAC10.html)
ES (1) ES472934A1 (cg-RX-API-DMAC10.html)
FR (1) FR2400037A1 (cg-RX-API-DMAC10.html)
GB (1) GB2002406B (cg-RX-API-DMAC10.html)
IT (1) IT1083903B (cg-RX-API-DMAC10.html)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2478646A2 (fr) * 1980-03-20 1981-09-25 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
SE449753B (sv) * 1978-11-06 1987-05-18 Choay Sa Mukopolysackaridkomposition med reglerande verkan pa koagulation, lekemedel innehallande densamma samt forfarande for framstellning derav
FR2461719A2 (fr) * 1979-07-20 1981-02-06 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
USRE35770E (en) * 1978-11-06 1998-04-14 Choay, S.A. Oligosaccharides having anti-Xa activity and pharmaceutical compositions containing them
CA1136620A (en) * 1979-01-08 1982-11-30 Ulf P.F. Lindahl Heparin fragments having selective anticoagulation activity
US4826827A (en) * 1979-10-05 1989-05-02 Choay S.A. Short chained oligosaccharides having biological properties, a process for making the same and the use thereof as drugs
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
US4281108A (en) * 1980-01-28 1981-07-28 Hepar Industries, Inc. Process for obtaining low molecular weight heparins endowed with elevated pharmacological properties, and product so obtained
JPS56120704A (en) * 1980-01-28 1981-09-22 Hepar Ind Inc Method of obtaining low molecular weight heparin having heightened pharmacologic property* product manufactured thereby and its use
CA1171375A (en) * 1980-09-15 1984-07-24 Ulf P.F. Lindahl Oligosaccharides having selective anticoagulation activity
US4385046A (en) * 1980-12-15 1983-05-24 Minnesota Mining And Manufacturing Company Diagnostic radio-labeled polysaccharide derivatives
FR2503714B1 (fr) * 1981-04-10 1986-11-21 Choay Sa Procede d'obtention de mucopolysaccharides biologiquement actifs, de purete elevee, par depolymerisation de l'heparine
FR2538404B1 (cg-RX-API-DMAC10.html) * 1982-12-28 1985-08-23 Anic Spa
IT1195497B (it) * 1983-03-08 1988-10-19 Opocrin Spa Procedimento per la preparazione di frazioni oligosaccaridiche dotate di proprieta' farmacologiche per degradazione chimica di eparina
IT1163772B (it) * 1983-07-13 1987-04-08 Baldacci Lab Spa Oligosaccaridi eterogenei complessabili ed alfa-idosani ad attivita' terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche
IT1214609B (it) * 1985-05-17 1990-01-18 Opocrin Spa Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono.
FR2584728B1 (fr) * 1985-07-12 1987-11-20 Choay Sa Procede de sulfatation de glycosaminoglycanes et de leurs fragments
US4745107A (en) * 1986-08-20 1988-05-17 Foley Kevin M Heparin derivatives with improved permeability
US4745105A (en) * 1986-08-20 1988-05-17 Griffin Charles C Low molecular weight heparin derivatives with improved permeability
US4942156A (en) * 1986-08-20 1990-07-17 Hepar Industries, Inc. Low molecular weight heparin derivatives having improved anti-Xa specificity
US4745106A (en) * 1986-08-20 1988-05-17 Griffin Charles C Heparin derivatives having improved anti-Xa specificity
IT1234508B (it) * 1988-06-10 1992-05-19 Alfa Wassermann Spa Derivati eparinici e procedimento per la loro preparazione
US4994367A (en) * 1988-10-07 1991-02-19 East Carolina University Extended shelf life platelet preparations and process for preparing the same
IT1237518B (it) * 1989-11-24 1993-06-08 Renato Conti Eparine supersolfatate
US7387253B1 (en) 1996-09-03 2008-06-17 Hand Held Products, Inc. Optical reader system comprising local host processor and optical reader
US5784102A (en) * 1995-05-15 1998-07-21 Welch Allyn, Inc. Optical reader having improved interactive image sensing and control circuitry
JP3342007B2 (ja) * 1997-11-20 2002-11-05 郁男 山科 低分子ヘパリン修飾体及び皮膚潰瘍治療剤
RU2169569C2 (ru) * 1999-06-18 2001-06-27 Республиканский центр функциональной и хирургической гастроэнтерологии Способ профилактики тромбогенных осложнений после длительных абдоминальных операций
US7270273B2 (en) 2001-01-22 2007-09-18 Hand Held Products, Inc. Optical reader having partial frame operating mode
DE60237553D1 (de) 2001-01-22 2010-10-14 Hand Held Prod Inc Optisches Lesegerät mit Partial-Frame-Betriebsmodus
US7268924B2 (en) 2001-01-22 2007-09-11 Hand Held Products, Inc. Optical reader having reduced parameter determination delay
EP1582531A1 (en) * 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
US20050261241A1 (en) * 2004-05-19 2005-11-24 Celsus Biopharmaceuticals, Inc. Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses
JP4679138B2 (ja) * 2004-12-24 2011-04-27 株式会社日本バリアフリー 高純度化されたムコ多糖類の製造方法
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
AU2020310172A1 (en) 2019-07-09 2022-03-03 Optimvia Llc Methods for synthesizing anticoagulant polysaccharides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB674607A (en) * 1949-10-20 1952-06-25 Roche Products Ltd Process for the manufacture of substances preventing the coagulation of blood
US2832766A (en) * 1952-04-17 1958-04-29 Univ Ohio State Res Found Sulfated aminopolysaccharides
DE968752C (de) * 1954-01-29 1958-03-27 Hoffmann La Roche Verfahren zur Herstellung von Chondroitinpolyschwefelsaeureestern
DE1032731B (de) * 1955-09-22 1958-06-26 Upjohn Co Verfahren zur selektiven Sulfatierung von Aminoalkoholen in der Aminogruppe
US3585184A (en) * 1967-12-29 1971-06-15 Univ Ohio State 2-amino - 2 - deoxy-d-glucopyrano-d-glucopyranans having the alpha-d-glucose configuration,method,and use

Also Published As

Publication number Publication date
FR2400037B1 (cg-RX-API-DMAC10.html) 1980-06-20
JPS5430277A (en) 1979-03-06
DE2833898A1 (de) 1979-02-22
AU3873878A (en) 1980-02-14
US4757057A (en) 1988-07-12
DK349678A (da) 1979-02-10
DE2833898C2 (cg-RX-API-DMAC10.html) 1988-06-23
JPS6234041B2 (cg-RX-API-DMAC10.html) 1987-07-24
GB2002406B (en) 1982-10-20
ES472934A1 (es) 1979-10-16
GB2002406A (en) 1979-02-21
DK159278B (da) 1990-09-24
CH642979A5 (it) 1984-05-15
FR2400037A1 (fr) 1979-03-09

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Effective date: 19960830