IT1099080B - Cefemi composti e procedimenti per la loro preparazione - Google Patents
Cefemi composti e procedimenti per la loro preparazioneInfo
- Publication number
- IT1099080B IT1099080B IT27624/78A IT2762478A IT1099080B IT 1099080 B IT1099080 B IT 1099080B IT 27624/78 A IT27624/78 A IT 27624/78A IT 2762478 A IT2762478 A IT 2762478A IT 1099080 B IT1099080 B IT 1099080B
- Authority
- IT
- Italy
- Prior art keywords
- cefemi
- procedures
- compound
- preparation
- compound cefemi
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3816377 | 1977-09-13 | ||
| GB4231577 | 1977-10-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7827624A0 IT7827624A0 (it) | 1978-09-13 |
| IT1099080B true IT1099080B (it) | 1985-09-18 |
Family
ID=26263716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT27624/78A IT1099080B (it) | 1977-09-13 | 1978-09-13 | Cefemi composti e procedimenti per la loro preparazione |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4370326A (it) |
| EP (1) | EP0001125B1 (it) |
| JP (1) | JPS5452096A (it) |
| DE (1) | DE2861317D1 (it) |
| IT (1) | IT1099080B (it) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4440766A (en) * | 1976-03-09 | 1984-04-03 | Fujisawa Pharmaceutical Co., Ltd. | 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds |
| US4427674A (en) | 1977-03-14 | 1984-01-24 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| MA18686A1 (fr) * | 1978-07-07 | 1980-10-01 | Ciba Geigy Ag | Composes aminothiazoliques |
| US4284631A (en) * | 1978-07-31 | 1981-08-18 | Fujisawa Pharmaceutical Co., Ltd. | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them |
| EP0048504B1 (en) * | 1978-09-12 | 1988-08-17 | Fujisawa Pharmaceutical Co., Ltd. | Intermediate compounds for preparing cephem compounds; processes for their preparation and processes for preparing cephem compounds |
| US4311698A (en) * | 1979-03-12 | 1982-01-19 | Haskell Theodore H | Aminoacid derivatives of cephalosporin compounds |
| EP0021688B1 (en) * | 1979-06-07 | 1983-07-13 | Yamanouchi Pharmaceutical Co., Ltd. | 7-(thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them |
| DE3069560D1 (en) * | 1979-09-03 | 1984-12-06 | Fujisawa Pharmaceutical Co | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them |
| GR78221B (it) * | 1980-02-01 | 1984-09-26 | Ciba Geigy Ag | |
| EP0054512A3 (de) * | 1980-12-12 | 1983-08-03 | Ciba-Geigy Ag | Cephalosporinester, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate |
| DK554481A (da) * | 1980-12-15 | 1982-06-16 | Fujisawa Pharmaceutical Co | Fremgangsmaade til fremstilling af cephalosporansyrederivater |
| JPS57154190A (en) * | 1980-12-22 | 1982-09-22 | Fujisawa Pharmaceut Co Ltd | 7-substituted cephalosporanic acid derivative and its preparation |
| JPS57193489A (en) * | 1981-05-21 | 1982-11-27 | Fujisawa Pharmaceut Co Ltd | Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation |
| US4683227A (en) * | 1985-07-09 | 1987-07-28 | Eli Lilly And Company | Antibiotic derivatives of 7β-[2-(thiazol-4-yl)acetamide]-3-chloro-3-cephem-4-carboxylic acids and compositions and method of use thereof |
| AU1630988A (en) * | 1987-05-30 | 1988-12-01 | Kyoto Pharmaceutical Industries, Ltd. | Cephalosporin compound and pharmaceutical composition thereof |
| KR950014571B1 (ko) * | 1991-11-18 | 1995-12-08 | 제일제당주식회사 | 세펨 유도체의 제조방법 |
| US20130065874A1 (en) | 2011-09-09 | 2013-03-14 | Cubist Pharmaceuticals, Inc. | Methods for treating intrapulmonary infections |
| US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
| US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
| US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
| US20140274991A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane pharmaceutical compositions |
| KR102226197B1 (ko) | 2013-03-15 | 2021-03-11 | 머크 샤프 앤드 돔 코포레이션 | 세프톨로잔 항균성 조성물 |
| AU2014233637A1 (en) | 2013-09-09 | 2015-03-26 | Merck Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
| US20150094293A1 (en) | 2013-09-27 | 2015-04-02 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE412238B (sv) * | 1971-05-24 | 1980-02-25 | Ciba Geigy | Forfarande for framstellning av 7 beta-amino-cefem-4-karboxylsyraforeningar genom dekarbonylering av en 3-formyl-cefem-4-karboxylsyraforening |
| CH591500A5 (it) * | 1972-06-29 | 1977-09-30 | Ciba Geigy Ag | |
| NZ176206A (en) * | 1973-12-25 | 1978-03-06 | Takeda Chemical Industries Ltd | Cephalosporins |
| US4191762A (en) * | 1974-03-14 | 1980-03-04 | Fujisawa Pharmaceutical Co., Ltd. | 2-Lower alkyl-7-substituted amino-2 or 3-cephem-4-carboxylic acid compounds |
| DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
| GB1536281A (en) * | 1975-06-09 | 1978-12-20 | Takeda Chemical Industries Ltd | Cephem compounds |
| US4147864A (en) * | 1975-02-20 | 1979-04-03 | Ciba-Geigy Corporation | Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds |
| DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
| GB1575803A (en) * | 1976-03-09 | 1980-10-01 | Fujisawa Pharmaceutical Co | 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof |
| US4152433A (en) * | 1976-03-12 | 1979-05-01 | Fujisawa Pharmaceutical Co., Ltd. | 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and pharmaceutical compositions |
| US4166115A (en) * | 1976-04-12 | 1979-08-28 | Fujisawa Pharmaceutical Co., Ltd. | Syn 7-oxoimino substituted derivatives of cephalosporanic acid |
| JPS53103493A (en) | 1977-02-18 | 1978-09-08 | Takeda Chem Ind Ltd | Cephalosporin derivatives and process for their preparation |
| DE2710902A1 (de) | 1977-03-12 | 1978-09-21 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| US4264597A (en) * | 1978-06-06 | 1981-04-28 | Masashi Hashimoto | Cephalosporin analogues and processes for the preparation thereof |
-
1978
- 1978-09-06 US US05/939,982 patent/US4370326A/en not_active Expired - Lifetime
- 1978-09-12 EP EP78100867A patent/EP0001125B1/en not_active Expired
- 1978-09-12 DE DE7878100867T patent/DE2861317D1/de not_active Expired
- 1978-09-13 IT IT27624/78A patent/IT1099080B/it active
- 1978-09-13 JP JP11313478A patent/JPS5452096A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE2861317D1 (en) | 1982-01-14 |
| JPS6341913B2 (it) | 1988-08-19 |
| EP0001125A3 (en) | 1979-04-18 |
| JPS5452096A (en) | 1979-04-24 |
| EP0001125B1 (en) | 1981-11-11 |
| EP0001125A2 (en) | 1979-03-21 |
| IT7827624A0 (it) | 1978-09-13 |
| US4370326A (en) | 1983-01-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT1098042B (it) | Mitroimmidazoli e procedimento per la loro preparazione | |
| IT1099080B (it) | Cefemi composti e procedimenti per la loro preparazione | |
| IT1092262B (it) | Spirolattoni e procedimento per la loro preparazione | |
| IT1156863B (it) | Composti di beta-lattame e procedimento per la loro preparazione | |
| IT1158712B (it) | Derivato di alchilen-ammine e procedimento per la loro preparazione | |
| IT1108968B (it) | Acetilenprostaglandine e procedimento per la loro preparazione | |
| IT1160450B (it) | Composti nitrosureici e procedimento per la loro preparazione | |
| IT1107653B (it) | Imidazo-chinolin-dioni e procedimento per la loro preparazione | |
| IT1106961B (it) | Composti antifungo ed antibatterici e procedimento per la loro preparazione | |
| IT1098013B (it) | Procedimento per la preparazione di furanoni | |
| IT1111459B (it) | Composti pesticidi e procedimento per la loro preparazione | |
| IT1108793B (it) | Antibiotici e procedimento per la loro preparazione | |
| IT1106888B (it) | Procedimento per la preparazione di idrossifenil-idantoina | |
| IT1104712B (it) | Alchilammine 1-fluorometil sostituite e procedimento per la loro preparazione | |
| IT1086270B (it) | Uracil-derivati e procedimento per la loro preparazione | |
| IT1165040B (it) | Alcossialchilidenidrazinopiridazione e procedimento per la loro preparazione | |
| IT1094627B (it) | 17 beta-idrossi-4-androsten-3-oni e procedimento per la loro preparazione | |
| IT1100210B (it) | 2,4-diammino-5-benzil-pirimidine e procedimento per la loro preparazione | |
| IT1104583B (it) | 3-di-n-profil-acetossi-benzo-diazepin-2-oni e procedimento per la loro preparazione | |
| IT1096292B (it) | Benzil-pirimidine e procedimento per la loro preparazione | |
| IT1112608B (it) | Polisaccaridi e procedimento per la loro preparazione | |
| IT1107695B (it) | Procedimento per la preparazione di 6-ossamordinani 6-sostituiti | |
| IT1109205B (it) | Procedimento per la preparazione di 4-clorochinoline | |
| IT1130215B (it) | 3-ariltio-4-idrossipirrolidine 1-sostituite e procedimento per la loro preparazione | |
| IT1107655B (it) | Isochinolindioni solforati e procedimento per la loro produzione |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970929 |