IS6724A - Aðferð til framleiðslu á N-arýl-anþranilískum sýrum og afleiðum þeirra - Google Patents
Aðferð til framleiðslu á N-arýl-anþranilískum sýrum og afleiðum þeirraInfo
- Publication number
- IS6724A IS6724A IS6724A IS6724A IS6724A IS 6724 A IS6724 A IS 6724A IS 6724 A IS6724 A IS 6724A IS 6724 A IS6724 A IS 6724A IS 6724 A IS6724 A IS 6724A
- Authority
- IS
- Iceland
- Prior art keywords
- aryl
- derivatives
- preparation
- anthranilic acids
- anthranilic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
- C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyridine Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22820600P | 2000-08-25 | 2000-08-25 | |
| PCT/US2001/022948 WO2002018319A1 (en) | 2000-08-25 | 2001-07-20 | Process for making n-aryl-anthranilic acids and their derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS6724A true IS6724A (is) | 2003-02-20 |
Family
ID=22856235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS6724A IS6724A (is) | 2000-08-25 | 2003-02-20 | Aðferð til framleiðslu á N-arýl-anþranilískum sýrum og afleiðum þeirra |
Country Status (31)
| Country | Link |
|---|---|
| EP (1) | EP1313694A1 (es) |
| JP (1) | JP2004507518A (es) |
| KR (1) | KR20030059115A (es) |
| CN (1) | CN1458921A (es) |
| AP (1) | AP2001002249A0 (es) |
| AR (1) | AR032175A1 (es) |
| AU (1) | AU2001277044A1 (es) |
| BG (1) | BG107635A (es) |
| BR (1) | BR0113520A (es) |
| CA (1) | CA2420003A1 (es) |
| CZ (1) | CZ2003477A3 (es) |
| DO (1) | DOP2001000238A (es) |
| EA (1) | EA200300187A1 (es) |
| GT (1) | GT200100174A (es) |
| HN (1) | HN2001000216A (es) |
| HU (1) | HUP0300828A2 (es) |
| IL (1) | IL154507A0 (es) |
| IS (1) | IS6724A (es) |
| MA (1) | MA26949A1 (es) |
| MX (1) | MXPA03001654A (es) |
| NO (1) | NO20030844L (es) |
| PA (1) | PA8526501A1 (es) |
| PE (1) | PE20020393A1 (es) |
| PL (1) | PL360699A1 (es) |
| SK (1) | SK2072003A3 (es) |
| SV (1) | SV2002000601A (es) |
| TN (1) | TNSN01127A1 (es) |
| UY (1) | UY26908A1 (es) |
| WO (1) | WO2002018319A1 (es) |
| YU (1) | YU14303A (es) |
| ZA (1) | ZA200301182B (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7235537B2 (en) | 2002-03-13 | 2007-06-26 | Array Biopharma, Inc. | N3 alkylated benzimidazole derivatives as MEK inhibitors |
| HUE025767T2 (en) | 2002-03-13 | 2016-05-30 | Array Biopharma Inc | N3-alkylated benzimidazole derivatives as MEK inhibitors |
| US7144907B2 (en) | 2003-09-03 | 2006-12-05 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
| US7538120B2 (en) | 2003-09-03 | 2009-05-26 | Array Biopharma Inc. | Method of treating inflammatory diseases |
| KR101013932B1 (ko) | 2003-10-21 | 2011-02-14 | 워너-램버트 캄파니 엘엘씨 | Ｎ-[(ｒ)-2,3-디히드록시-프로폭시]-3,4-디플루오로-2-(2-플루오로-4-요오도페닐아미노)-벤자미드 다형체 형태 |
| AU2004293019B2 (en) | 2003-11-19 | 2010-10-28 | Array Biopharma Inc. | Bicyclic inhibitors of MEK and methods of use thereof |
| US7732616B2 (en) | 2003-11-19 | 2010-06-08 | Array Biopharma Inc. | Dihydropyridine and dihydropyridazine derivatives as inhibitors of MEK and methods of use thereof |
| US7517994B2 (en) | 2003-11-19 | 2009-04-14 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
| EP1684694A2 (en) | 2003-11-21 | 2006-08-02 | Array Biopharma, Inc. | Akt protein kinase inhibitors |
| UA89035C2 (ru) * | 2003-12-03 | 2009-12-25 | Лео Фарма А/С | Эфиры гидроксамовых кислот и их фармацевтическое применение |
| JP5154406B2 (ja) | 2005-04-13 | 2013-02-27 | アステックス、セラピューティックス、リミテッド | 医薬化合物 |
| ES2405785T3 (es) | 2005-05-18 | 2013-06-03 | Array Biopharma Inc. | Inhibidores heterocíclicos de MEK y métodos de uso de los mismos |
| US7754725B2 (en) | 2006-03-01 | 2010-07-13 | Astex Therapeutics Ltd. | Dihydroxyphenyl isoindolymethanones |
| EP2054418B1 (en) | 2006-07-06 | 2011-11-09 | Array Biopharma Inc. | Dihydrothieno pyrimidines as akt protein kinase inhibitors |
| US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| ATE493418T1 (de) | 2006-07-06 | 2011-01-15 | Array Biopharma Inc | Dihydrofuropyrimidine als akt- proteinkinaseinhibitoren |
| CA2656618C (en) | 2006-07-06 | 2014-08-26 | Array Biopharma Inc. | Cyclopenta [d] pyrimidines as akt protein kinase inhibitors |
| US8277807B2 (en) | 2006-10-12 | 2012-10-02 | Astex Therapeutics Limited | Pharmaceutical combinations |
| GB0620259D0 (en) | 2006-10-12 | 2006-11-22 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| WO2008044054A2 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Hydroxy-substituted benzoic acid amide compounds for use in therapy |
| WO2008044045A1 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical combinations |
| WO2008044027A2 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical compounds having hsp90 inhibitory or modulating activity |
| WO2008044041A1 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical combinations |
| US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
| JP5542282B2 (ja) | 2007-07-05 | 2014-07-09 | アレイ バイオファーマ、インコーポレイテッド | Ａｋｔプロテインキナーゼ阻害剤としてのピリミジルシクロペンタン |
| US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| CN101801955B (zh) | 2007-07-05 | 2013-05-08 | 阵列生物制药公司 | 作为akt蛋白激酶抑制剂的嘧啶基环戊烷 |
| AU2009204025B2 (en) | 2008-01-09 | 2014-02-20 | Array Biopharma Inc. | Hydroxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| AU2009204019B2 (en) | 2008-01-09 | 2014-02-20 | Array Biopharma Inc. | Hydroxylated pyrimidyl cyclopentane as AKT protein kinase inhibitor |
| GB0806527D0 (en) | 2008-04-11 | 2008-05-14 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| CN101985428B (zh) * | 2009-07-29 | 2014-02-12 | 杭州民生药业有限公司 | 邻苯胺基苯甲酸衍生物或其药学上可接受的盐、其制备方法及其用途 |
| EP2536682A1 (fr) * | 2010-02-19 | 2012-12-26 | Centre National De La Recherche Scientifique | Procede de preparation de composes chimiques d'interet par substitution nucleophile aromatique de derives d'acides carboxyliques aromatiques portant au moins un groupement electroattracteur |
| CA2789361A1 (en) * | 2010-02-19 | 2011-08-25 | Jacques Mortier | Method for preparing chemical compounds of interest by aromatic nucleophilic substitution |
| RU2631240C2 (ru) | 2011-04-01 | 2017-09-20 | Дженентек, Инк. | Комбинации соединений-ингибиторов акт и абиратерона, и способы применения |
| MX2013011333A (es) | 2011-04-01 | 2014-04-16 | Genentech Inc | Combinaciones de compuestos inhibidores de akt y mek, y metodos de uso. |
| SI2909188T1 (en) * | 2012-10-12 | 2018-07-31 | Exelixis, Inc. | A novel process for the manufacture of compounds for use in the treatment of cancer |
| CN112745237B (zh) * | 2019-10-29 | 2023-06-20 | 中国科学院上海药物研究所 | 2-芳基胺类化合物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3138636A (en) * | 1960-06-23 | 1964-06-23 | Parke Davis & Co | Anthranilic acid derivatives |
| US6251943B1 (en) * | 1997-02-28 | 2001-06-26 | Warner-Lambert Company | Method of treating or preventing septic shock by administering a MEK inhibitor |
| DE69836378T2 (de) * | 1997-07-01 | 2007-10-11 | Warner-Lambert Co. Llc | Benzoesäure- und Benzamid-Derivate von Anthranilsäure und ihre Anwendung als MEK-Inhibitoren |
| PT993439E (pt) * | 1997-07-01 | 2004-12-31 | Warner Lambert Co | Derivados de acido 4-bromo ou 4-iodofenilaminobenzidroxamico e sua utilizacao como inibidores de mek |
| CA2348236A1 (en) * | 1999-01-13 | 2000-07-20 | Stephen Douglas Barrett | 4-arylamino, 4-aryloxy, and 4-arylthio diarylamines and derivatives thereof as selective mek inhibitors |
| DK1171418T3 (da) * | 1999-04-21 | 2005-05-09 | Warner Lambert Co | Fremgangsmåde til fremstilling af 2-(N-phenylamino)benzoesyrer |
-
2001
- 2001-07-20 CN CN01815869A patent/CN1458921A/zh active Pending
- 2001-07-20 AU AU2001277044A patent/AU2001277044A1/en not_active Abandoned
- 2001-07-20 MX MXPA03001654A patent/MXPA03001654A/es unknown
- 2001-07-20 PL PL36069901A patent/PL360699A1/xx unknown
- 2001-07-20 EP EP01954824A patent/EP1313694A1/en not_active Withdrawn
- 2001-07-20 SK SK207-2003A patent/SK2072003A3/sk unknown
- 2001-07-20 WO PCT/US2001/022948 patent/WO2002018319A1/en not_active Application Discontinuation
- 2001-07-20 EA EA200300187A patent/EA200300187A1/ru unknown
- 2001-07-20 YU YU14303A patent/YU14303A/sh unknown
- 2001-07-20 AP APAP/P/2001/002249A patent/AP2001002249A0/en unknown
- 2001-07-20 IL IL15450701A patent/IL154507A0/xx unknown
- 2001-07-20 KR KR10-2003-7002675A patent/KR20030059115A/ko not_active Application Discontinuation
- 2001-07-20 HU HU0300828A patent/HUP0300828A2/hu unknown
- 2001-07-20 CA CA002420003A patent/CA2420003A1/en not_active Abandoned
- 2001-07-20 BR BR0113520-1A patent/BR0113520A/pt not_active Application Discontinuation
- 2001-07-20 JP JP2002523437A patent/JP2004507518A/ja active Pending
- 2001-07-20 CZ CZ2003477A patent/CZ2003477A3/cs unknown
- 2001-08-15 SV SV2001000601A patent/SV2002000601A/es not_active Application Discontinuation
- 2001-08-22 TN TNTNSN01127A patent/TNSN01127A1/en unknown
- 2001-08-23 PA PA20018526501A patent/PA8526501A1/es unknown
- 2001-08-24 DO DO2001000238A patent/DOP2001000238A/es unknown
- 2001-08-24 AR ARP010104047A patent/AR032175A1/es unknown
- 2001-08-24 GT GT200100174A patent/GT200100174A/es unknown
- 2001-08-24 PE PE2001000853A patent/PE20020393A1/es not_active Application Discontinuation
- 2001-08-24 UY UY26908A patent/UY26908A1/es not_active Application Discontinuation
- 2001-09-26 HN HN2001000216A patent/HN2001000216A/es unknown
-
2003
- 2003-02-12 ZA ZA200301182A patent/ZA200301182B/en unknown
- 2003-02-20 IS IS6724A patent/IS6724A/is unknown
- 2003-02-24 NO NO20030844A patent/NO20030844L/no not_active Application Discontinuation
- 2003-03-13 BG BG107635A patent/BG107635A/bg unknown
- 2003-03-14 MA MA27069A patent/MA26949A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG107635A (bg) | 2004-09-30 |
| CN1458921A (zh) | 2003-11-26 |
| KR20030059115A (ko) | 2003-07-07 |
| JP2004507518A (ja) | 2004-03-11 |
| TNSN01127A1 (en) | 2005-11-10 |
| AR032175A1 (es) | 2003-10-29 |
| SV2002000601A (es) | 2002-04-03 |
| NO20030844D0 (no) | 2003-02-24 |
| ZA200301182B (en) | 2004-05-12 |
| NO20030844L (no) | 2003-02-25 |
| SK2072003A3 (en) | 2004-01-08 |
| GT200100174A (es) | 2002-07-18 |
| IL154507A0 (en) | 2003-09-17 |
| PL360699A1 (en) | 2004-09-20 |
| MA26949A1 (fr) | 2004-12-20 |
| EP1313694A1 (en) | 2003-05-28 |
| WO2002018319A1 (en) | 2002-03-07 |
| BR0113520A (pt) | 2003-06-24 |
| PA8526501A1 (es) | 2002-07-30 |
| CZ2003477A3 (cs) | 2003-10-15 |
| HN2001000216A (es) | 2002-05-22 |
| AP2001002249A0 (en) | 2001-09-30 |
| CA2420003A1 (en) | 2002-03-07 |
| PE20020393A1 (es) | 2002-05-09 |
| EA200300187A1 (ru) | 2003-08-28 |
| MXPA03001654A (es) | 2004-09-10 |
| YU14303A (sh) | 2006-08-17 |
| DOP2001000238A (es) | 2003-01-31 |
| UY26908A1 (es) | 2001-11-30 |
| AU2001277044A1 (en) | 2002-03-13 |
| HUP0300828A2 (hu) | 2003-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IS6724A (is) | Aðferð til framleiðslu á N-arýl-anþranilískum sýrum og afleiðum þeirra | |
| IS2290B (is) | Aðferð til framleiðslu á díhýdroxýesterum og afleiðum þeirra | |
| IS2223B (is) | Aðferð til framleiðslu á 5-sýanóþalíði | |
| IS2468B (is) | Aðferðir og milliefni til framleiðslu á efnasamböndum gegn krabbameini | |
| IS2261B (is) | Aðferð til framleiðslu á 5-sýanóþalíði | |
| NO20034079D0 (no) | Fremgangsmåte for fremstilling av interpolymerer og produkter laget derav | |
| IS2711B3 (is) | Aðferð til framleiðslu á amín platínu komplexum | |
| DK1341414T3 (da) | Marint actinomycet-taxon til opdagelse af medikamenter og fermenteringsprodukter | |
| NO20015542D0 (no) | Fremgangsmåte for fremstilling og anvendelse av N- desmetylzopikloner | |
| IS6487A (is) | Aðferð til framleiðslu á Sítalóprami | |
| NO20012963D0 (no) | Fremgangsmåte for fremstilling av 3-alkanoylindoler og 3- alkylindoler | |
| NO20031701D0 (no) | Fremgangsmåte og mellomprodukter i fremstilling av 7- substituerte antiöstrogener | |
| NO20003555L (no) | Fremgangsmåte ved fremstilling av konstruksjonselementer og de resulterende elementer | |
| IS5627A (is) | Svefnlyfs ß-karbólín afleiður, aðferð til framleiðslu á þeim og notkun þeirra sem læknislyfja | |
| DK1339723T3 (da) | Fremgangsmåde og ester derivater anvendelige til fremstilling af cefalosporiner | |
| DK1341758T3 (da) | Coniosetin og derivater af denne, fremgangsmåde til fremstilling og anvendelse af samme | |
| NO20030515D0 (no) | Fremgangsmåte for fremstilling av dinapsolin | |
| GB2384779B (en) | Method for the production of tagged proteins | |
| NO20030587L (no) | Fremgangsmåte til fremstilling av diskodermolid og analoger derav | |
| IS5212A (is) | Bætt aðferð til framleiðslu á pýrazólópýrimidínónafleiðu | |
| NO20011921D0 (no) | Sulfidoamidokarboksylsyrer, metoder for fremstilling derav og anvendelser derav | |
| NO20023702D0 (no) | Fremgangsmåte for fremstilling av 5-arylnikotinaldehyder | |
| NO20014449L (no) | Fremgangsmåte for fremstilling av 5-amino-8- alkylkinolonkarboksylsyrederivater og mellomprodukter ifremstillingen derav | |
| NO20023687D0 (no) | 1,3,4-oksadiazolderivater og fremgangsmåte for fremstilling derav | |
| IS6615A (is) | Aðferð til að búa til sýklóprópýlkarboxýlsýruestera og afleiður |