DK1341414T3 - Marint actinomycet-taxon til opdagelse af medikamenter og fermenteringsprodukter - Google Patents
Marint actinomycet-taxon til opdagelse af medikamenter og fermenteringsprodukterInfo
- Publication number
- DK1341414T3 DK1341414T3 DK01989109.2T DK01989109T DK1341414T3 DK 1341414 T3 DK1341414 T3 DK 1341414T3 DK 01989109 T DK01989109 T DK 01989109T DK 1341414 T3 DK1341414 T3 DK 1341414T3
- Authority
- DK
- Denmark
- Prior art keywords
- marint
- actinomycet
- taxon
- medicines
- discovery
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/10—Protozoa; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/36—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Actinomyces; from Streptomyces (G)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24935600P | 2000-11-16 | 2000-11-16 | |
PCT/US2001/043758 WO2002047610A2 (en) | 2000-11-16 | 2001-11-16 | Marine actinomycete taxon for drug and fermentation product dicovery |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1341414T3 true DK1341414T3 (da) | 2013-03-25 |
Family
ID=22943113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01989109.2T DK1341414T3 (da) | 2000-11-16 | 2001-11-16 | Marint actinomycet-taxon til opdagelse af medikamenter og fermenteringsprodukter |
Country Status (8)
Country | Link |
---|---|
US (5) | US7144723B2 (da) |
EP (1) | EP1341414B1 (da) |
JP (2) | JP4395549B2 (da) |
AU (2) | AU4322802A (da) |
CA (1) | CA2429163C (da) |
DK (1) | DK1341414T3 (da) |
ES (1) | ES2402045T3 (da) |
WO (1) | WO2002047610A2 (da) |
Families Citing this family (32)
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AU4322802A (en) | 2000-11-16 | 2002-06-24 | Univ California | Marine actinomycete taxon for drug and fermentation product dicovery |
US7179834B2 (en) * | 2002-06-24 | 2007-02-20 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
US7176232B2 (en) | 2002-06-24 | 2007-02-13 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
DE602004024037D1 (de) * | 2003-02-14 | 2009-12-24 | Intermed Discovery Gmbh | Substituierte heterozyklen |
ZA200600473B (en) * | 2003-06-20 | 2007-04-25 | Univ California | Salinosporamides and methods for use thereof |
NZ544588A (en) * | 2003-06-20 | 2010-06-25 | Nereus Pharmaceuticals Inc | Use of salinosporamide A and analogs thereof for the treatment of cancer, inflammation and infectious diseases |
SI2441767T1 (sl) | 2003-06-20 | 2015-10-30 | The Regents Of The University Of California | Salinosporamidi in metode za njihovo uporabo |
US7371875B2 (en) * | 2004-03-12 | 2008-05-13 | Miikana Therapeutics, Inc. | Cytotoxic agents and methods of use |
US7183417B2 (en) | 2004-04-09 | 2007-02-27 | President And Fellows Of Harvard College | Simple stereocontrolled synthesis of salinosporamide A |
US7579371B2 (en) | 2004-04-30 | 2009-08-25 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
EP1812443A2 (en) | 2004-04-30 | 2007-08-01 | Nereus Pharmaceuticals, Inc. | [3.2.0] heterocyclic compounds and methods of using the same |
EP1835910A2 (en) * | 2004-12-03 | 2007-09-26 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
US20070225350A1 (en) | 2004-12-03 | 2007-09-27 | Anderson Kenneth C | Compositions and methods for treating neoplastic diseases |
US7691896B2 (en) * | 2005-08-10 | 2010-04-06 | President And Fellows Of Harvard College | Analogs of salinosporamide A |
WO2007030662A1 (en) | 2005-09-09 | 2007-03-15 | Nereus Pharmaceuticals, Inc. | Biosynthesis of salinosporamide a and its analogs |
US7465720B2 (en) * | 2005-09-12 | 2008-12-16 | President And Fellows Of Harvard College | Proteasome inhibiting β-lactam compounds |
NZ596653A (en) | 2006-04-06 | 2012-10-26 | Nereus Pharmaceuticals Inc | Total synthesis of salinosporamide a and analogs thereof |
US20090325208A1 (en) * | 2006-06-26 | 2009-12-31 | Moore Bradley S | Biosynthesis of Salinosporamide A and Analogs and Methods Thereof |
US8986971B2 (en) | 2006-09-22 | 2015-03-24 | Triphase Research And Development I Corp. | Salt formulations for the fermentation of marine microorganisms |
WO2008095195A2 (en) * | 2007-02-02 | 2008-08-07 | Nereus Pharmaceuticals, Inc. | Lyophilized formulations of salinosporamide a |
WO2008137780A2 (en) * | 2007-05-04 | 2008-11-13 | Nereus Pharmaceuticals, Inc. | Use of [3.2.0] heterocyclic compounds and analogs thereof for treating infectious diseases |
US8394816B2 (en) * | 2007-12-07 | 2013-03-12 | Irene Ghobrial | Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia |
MX2010009860A (es) | 2008-03-07 | 2010-09-30 | Nereus Pharmaceuticals Inc | Sintesis total de salinosporamida a y sus analogos. |
US20090285836A1 (en) * | 2008-04-14 | 2009-11-19 | Nereus Pharmaceuticals, Inc. | Use of salinosporamide a to inhibit metastasis |
MX2010012341A (es) | 2008-05-12 | 2010-12-06 | Nereus Pharmaceuticals Inc | Derivados de salinosporamida como inhibidores de proteasoma. |
US9664677B2 (en) | 2010-04-19 | 2017-05-30 | Massachusetts Institute Of Technology | Polymer-nanostructure composition for selective molecular recognition |
EA201991715A1 (ru) * | 2013-09-27 | 2020-03-31 | Дженентек, Инк. | Композиции, содержащие антитело к pdl1 |
US10213526B2 (en) | 2014-03-21 | 2019-02-26 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix |
US10144719B1 (en) | 2015-07-27 | 2018-12-04 | University Of South Florida | Antimicrobials from an epigenetics based fungal metabolite screening program |
CA3011294A1 (en) | 2016-01-13 | 2017-07-20 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Vascular extracellular matrix hydrogel |
JP7171550B2 (ja) | 2016-06-01 | 2022-11-15 | セルジュヌ アンテルナシオナル ドゥジエム ソシエテ ア レスポンサビリテ リミティー | 中枢神経系(cns)がんの処置のためのマリゾミブの使用 |
JP2019524894A (ja) | 2016-08-19 | 2019-09-05 | セルジーン インターナショナル ツー エスアーエールエル | マリゾミブのモルフィック形態およびその使用 |
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US5276182A (en) | 1990-07-09 | 1994-01-04 | The Dow Chemical Company | Process for preparing polyurea oligomers |
DE4039602A1 (de) | 1990-12-12 | 1992-06-17 | Bauer Kurt Heinz Prof Dr | Pharmazeutische formulierungen |
KR100221695B1 (ko) | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | 약학적 구상 제형 |
US5653962A (en) | 1991-12-12 | 1997-08-05 | Glaxo Group Limited | Aerosol formulations containing P134a and particulate medicaments |
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US5654286A (en) | 1993-05-12 | 1997-08-05 | Hostetler; Karl Y. | Nucleotides for topical treatment of psoriasis, and methods for using same |
RU2150942C1 (ru) | 1993-10-01 | 2000-06-20 | Синтекс (Ю.ЭС.ЭЙ.) Инк. | Оральные суспензии, содержащие высокие дозы мофетила микофенолята |
US5707641A (en) | 1994-10-13 | 1998-01-13 | Pharmaderm Research & Development Ltd. | Formulations comprising therapeutically-active proteins or polypeptides |
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US6335358B1 (en) * | 1995-04-12 | 2002-01-01 | President And Fellows Of Harvard College | Lactacystin analogs |
US6838477B2 (en) | 1995-04-12 | 2005-01-04 | President And Fellows Of Harvard College | Lactacystin analogs |
US5653987A (en) | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
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AU4322802A (en) | 2000-11-16 | 2002-06-24 | Univ California | Marine actinomycete taxon for drug and fermentation product dicovery |
EP1492545B1 (de) * | 2002-04-05 | 2010-09-15 | ViroLogik GmbH | Mittel zur behandlung von flaviviridae-infektionen |
US7176232B2 (en) * | 2002-06-24 | 2007-02-13 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
US7179834B2 (en) | 2002-06-24 | 2007-02-20 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
DE602004024037D1 (de) * | 2003-02-14 | 2009-12-24 | Intermed Discovery Gmbh | Substituierte heterozyklen |
NZ544588A (en) * | 2003-06-20 | 2010-06-25 | Nereus Pharmaceuticals Inc | Use of salinosporamide A and analogs thereof for the treatment of cancer, inflammation and infectious diseases |
US7371875B2 (en) * | 2004-03-12 | 2008-05-13 | Miikana Therapeutics, Inc. | Cytotoxic agents and methods of use |
US7183417B2 (en) * | 2004-04-09 | 2007-02-27 | President And Fellows Of Harvard College | Simple stereocontrolled synthesis of salinosporamide A |
WO2005099687A2 (en) * | 2004-04-09 | 2005-10-27 | President And Fellows Of Harvard College | Analogs of salinosporamide a |
EP1812443A2 (en) * | 2004-04-30 | 2007-08-01 | Nereus Pharmaceuticals, Inc. | [3.2.0] heterocyclic compounds and methods of using the same |
US7579371B2 (en) * | 2004-04-30 | 2009-08-25 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
US20060264495A1 (en) * | 2004-04-30 | 2006-11-23 | Michael Palladino | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
US20070225350A1 (en) * | 2004-12-03 | 2007-09-27 | Anderson Kenneth C | Compositions and methods for treating neoplastic diseases |
US20060287520A1 (en) * | 2005-05-16 | 2006-12-21 | Danishefsky Samuel J | Synthesis of salinosporamide A and analogues thereof |
WO2007030662A1 (en) | 2005-09-09 | 2007-03-15 | Nereus Pharmaceuticals, Inc. | Biosynthesis of salinosporamide a and its analogs |
US8088923B2 (en) * | 2006-07-07 | 2012-01-03 | The Texas A&M University System | Cyclic-fused beta-lactones and their synthesis |
WO2008137780A2 (en) * | 2007-05-04 | 2008-11-13 | Nereus Pharmaceuticals, Inc. | Use of [3.2.0] heterocyclic compounds and analogs thereof for treating infectious diseases |
MX2010012341A (es) * | 2008-05-12 | 2010-12-06 | Nereus Pharmaceuticals Inc | Derivados de salinosporamida como inhibidores de proteasoma. |
-
2001
- 2001-11-16 AU AU4322802A patent/AU4322802A/xx active Pending
- 2001-11-16 WO PCT/US2001/043758 patent/WO2002047610A2/en active IP Right Grant
- 2001-11-16 AU AU2002243228A patent/AU2002243228B2/en not_active Expired
- 2001-11-16 CA CA2429163A patent/CA2429163C/en not_active Expired - Lifetime
- 2001-11-16 ES ES01989109T patent/ES2402045T3/es not_active Expired - Lifetime
- 2001-11-16 US US09/991,518 patent/US7144723B2/en not_active Expired - Lifetime
- 2001-11-16 DK DK01989109.2T patent/DK1341414T3/da active
- 2001-11-16 JP JP2002549186A patent/JP4395549B2/ja not_active Expired - Lifetime
- 2001-11-16 EP EP01989109A patent/EP1341414B1/en not_active Expired - Lifetime
-
2005
- 2005-09-15 US US11/228,416 patent/US20060008852A1/en not_active Abandoned
-
2007
- 2007-08-20 US US11/841,588 patent/US7879576B2/en not_active Expired - Lifetime
- 2007-12-05 JP JP2007314720A patent/JP2008119001A/ja active Pending
- 2007-12-28 US US11/966,801 patent/US20090197937A1/en not_active Abandoned
- 2007-12-28 US US11/966,787 patent/US7928138B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2002047610A3 (en) | 2002-10-10 |
JP4395549B2 (ja) | 2010-01-13 |
US7928138B2 (en) | 2011-04-19 |
CA2429163C (en) | 2013-02-12 |
AU4322802A (en) | 2002-06-24 |
EP1341414B1 (en) | 2013-01-02 |
AU2002243228B2 (en) | 2007-08-02 |
JP2008119001A (ja) | 2008-05-29 |
AU2002243228B8 (en) | 2002-06-24 |
US20090197937A1 (en) | 2009-08-06 |
US20090069401A1 (en) | 2009-03-12 |
CA2429163A1 (en) | 2002-06-20 |
US20080070273A1 (en) | 2008-03-20 |
JP2004535766A (ja) | 2004-12-02 |
US20060008852A1 (en) | 2006-01-12 |
WO2002047610A2 (en) | 2002-06-20 |
US7144723B2 (en) | 2006-12-05 |
EP1341414A2 (en) | 2003-09-10 |
ES2402045T3 (es) | 2013-04-26 |
US20030157695A1 (en) | 2003-08-21 |
US7879576B2 (en) | 2011-02-01 |
EP1341414A4 (en) | 2004-08-04 |
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