DK1263719T3 - N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse. - Google Patents

N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse.

Info

Publication number
DK1263719T3
DK1263719T3 DK01921326T DK01921326T DK1263719T3 DK 1263719 T3 DK1263719 T3 DK 1263719T3 DK 01921326 T DK01921326 T DK 01921326T DK 01921326 T DK01921326 T DK 01921326T DK 1263719 T3 DK1263719 T3 DK 1263719T3
Authority
DK
Denmark
Prior art keywords
deacetylthiocolchine
derivatives
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
DK01921326T
Other languages
English (en)
Inventor
Ezio Bombardelli
Alessandro Pontiroli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK1263719T3 publication Critical patent/DK1263719T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
DK01921326T 2000-03-17 2001-03-12 N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse. DK1263719T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI000554A IT1318401B1 (it) 2000-03-17 2000-03-17 Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono.
PCT/EP2001/002739 WO2001068597A1 (en) 2000-03-17 2001-03-12 N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DK1263719T3 true DK1263719T3 (da) 2009-11-16

Family

ID=11444502

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01921326T DK1263719T3 (da) 2000-03-17 2001-03-12 N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse.

Country Status (22)

Country Link
US (1) US6627774B2 (da)
EP (1) EP1263719B1 (da)
JP (1) JP4614608B2 (da)
KR (1) KR100761577B1 (da)
CN (1) CN1169788C (da)
AU (2) AU4834101A (da)
CA (1) CA2403110C (da)
CZ (1) CZ303386B6 (da)
DE (1) DE60139306D1 (da)
DK (1) DK1263719T3 (da)
ES (1) ES2327386T3 (da)
HK (1) HK1052168A1 (da)
HU (1) HU228790B1 (da)
IL (2) IL151715A0 (da)
IT (1) IT1318401B1 (da)
NO (1) NO329428B1 (da)
PL (1) PL201575B1 (da)
PT (1) PT1263719E (da)
RU (1) RU2257379C2 (da)
SI (1) SI1263719T1 (da)
SK (1) SK287108B6 (da)
WO (1) WO2001068597A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6825236B2 (en) * 2003-04-14 2004-11-30 California Pacific Medical Center Colchicine derivatives
ITMI20040164A1 (it) * 2004-02-03 2004-05-03 Indena Spa Derivati di n.deacetiltiocolchicina loro uso e formulazioni farmaceutiche che li contengono
CA3054535A1 (en) * 2005-02-18 2006-08-24 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
CA2598213C (en) * 2005-02-18 2011-04-19 Abraxis Bioscience, Inc. Drugs with improved hydrophobicity for incorporation in medical devices
US20080280987A1 (en) * 2006-08-31 2008-11-13 Desai Neil P Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases
JP2010502603A (ja) * 2006-08-31 2010-01-28 アブラクシス バイオサイエンス， エルエルシー 血管形成を阻害し、血管形成関連疾患を処置する方法
CA2755121A1 (en) * 2009-03-13 2010-09-16 Neil P. Desai Combination therapy with thiocolchicine derivatives
EP2924022A1 (en) * 2014-03-27 2015-09-30 INDENA S.p.A. Amorphous form of a thiocolchicine derivative

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1359637A (fr) * 1962-10-29 1964-04-30 Roussel Uclaf Dérivés de la cochicine et de la thiocolchicine et procédé de préparation
US4533675A (en) * 1984-04-17 1985-08-06 The United States Of America As Represented By The Department Of Health And Human Services Carbamates of colchicine for treatment of gout
AU641361B2 (en) * 1988-05-02 1993-09-23 Zynaxis Technologies, Incorporated Compounds, compositions and method for binding bio-affecting substances to surface membranes of bio-particles
US5433675A (en) * 1993-11-29 1995-07-18 Excelermatic Inc. Traction roller transmission
IT1276996B1 (it) * 1995-06-27 1997-11-04 Indena Spa Derivati della colchicina, loro uso e formulazioni che li contengono
IT1283110B1 (it) * 1996-06-07 1998-04-07 Indena Spa Composti a scheletro colchicinico,loro uso come farmaci e composizioni che li contengono

Also Published As

Publication number Publication date
KR100761577B1 (ko) 2007-10-04
RU2257379C2 (ru) 2005-07-27
PL357375A1 (en) 2004-07-26
HUP0300557A2 (hu) 2003-07-28
IT1318401B1 (it) 2003-08-25
ES2327386T3 (es) 2009-10-29
AU4834101A (en) 2001-09-24
CN1169788C (zh) 2004-10-06
SK287108B6 (sk) 2009-12-07
NO20024354D0 (no) 2002-09-12
CN1418190A (zh) 2003-05-14
ITMI20000554A1 (it) 2001-09-17
EP1263719B1 (en) 2009-07-22
PL201575B1 (pl) 2009-04-30
HK1052168A1 (en) 2003-09-05
SK13102002A3 (sk) 2002-12-03
IL151715A (en) 2007-12-03
NO20024354L (no) 2002-09-12
SI1263719T1 (sl) 2009-10-31
DE60139306D1 (de) 2009-09-03
AU2001248341B2 (en) 2005-01-27
US20030055111A1 (en) 2003-03-20
CA2403110C (en) 2009-12-15
CZ303386B6 (cs) 2012-08-29
HUP0300557A3 (en) 2004-08-30
WO2001068597A1 (en) 2001-09-20
EP1263719A1 (en) 2002-12-11
RU2002124524A (ru) 2004-03-20
JP2003527371A (ja) 2003-09-16
ITMI20000554A0 (it) 2000-03-17
HU228790B1 (en) 2013-05-28
NO329428B1 (no) 2010-10-18
US6627774B2 (en) 2003-09-30
IL151715A0 (en) 2003-04-10
KR20020091123A (ko) 2002-12-05
CA2403110A1 (en) 2001-09-20
PT1263719E (pt) 2009-08-20
JP4614608B2 (ja) 2011-01-19

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