DK1263719T3 - N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse. - Google Patents

N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse.

Info

Publication number
DK1263719T3
DK1263719T3 DK01921326T DK01921326T DK1263719T3 DK 1263719 T3 DK1263719 T3 DK 1263719T3 DK 01921326 T DK01921326 T DK 01921326T DK 01921326 T DK01921326 T DK 01921326T DK 1263719 T3 DK1263719 T3 DK 1263719T3
Authority
DK
Denmark
Prior art keywords
deacetylthiocolchine
derivatives
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
DK01921326T
Other languages
English (en)
Inventor
Ezio Bombardelli
Alessandro Pontiroli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK1263719T3 publication Critical patent/DK1263719T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK01921326T 2000-03-17 2001-03-12 N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse. DK1263719T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI000554A IT1318401B1 (it) 2000-03-17 2000-03-17 Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono.
PCT/EP2001/002739 WO2001068597A1 (en) 2000-03-17 2001-03-12 N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DK1263719T3 true DK1263719T3 (da) 2009-11-16

Family

ID=11444502

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01921326T DK1263719T3 (da) 2000-03-17 2001-03-12 N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse.

Country Status (22)

Country Link
US (1) US6627774B2 (da)
EP (1) EP1263719B1 (da)
JP (1) JP4614608B2 (da)
KR (1) KR100761577B1 (da)
CN (1) CN1169788C (da)
AU (2) AU4834101A (da)
CA (1) CA2403110C (da)
CZ (1) CZ303386B6 (da)
DE (1) DE60139306D1 (da)
DK (1) DK1263719T3 (da)
ES (1) ES2327386T3 (da)
HK (1) HK1052168A1 (da)
HU (1) HU228790B1 (da)
IL (2) IL151715A0 (da)
IT (1) IT1318401B1 (da)
NO (1) NO329428B1 (da)
PL (1) PL201575B1 (da)
PT (1) PT1263719E (da)
RU (1) RU2257379C2 (da)
SI (1) SI1263719T1 (da)
SK (1) SK287108B6 (da)
WO (1) WO2001068597A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6825236B2 (en) * 2003-04-14 2004-11-30 California Pacific Medical Center Colchicine derivatives
ITMI20040164A1 (it) * 2004-02-03 2004-05-03 Indena Spa Derivati di n.deacetiltiocolchicina loro uso e formulazioni farmaceutiche che li contengono
ES2663495T3 (es) * 2005-02-18 2018-04-13 Abraxis Bioscience, Llc Fármacos con hidrofobicidad mejorada para incorporación en dispositivos médicos
PT1853250E (pt) * 2005-02-18 2012-02-03 Abraxis Bioscience Llc Combinações e modos de administração de agentes terapêuticos e terapia de combinação
CA2662140A1 (en) * 2006-08-31 2008-03-06 Abraxis Bioscience, Llc Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases
US20080280987A1 (en) * 2006-08-31 2008-11-13 Desai Neil P Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases
US20120189701A1 (en) * 2009-03-13 2012-07-26 Desai Neil P Combination therapy with thiocolchicine derivatives
EP2924022A1 (en) * 2014-03-27 2015-09-30 INDENA S.p.A. Amorphous form of a thiocolchicine derivative

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1359637A (fr) * 1962-10-29 1964-04-30 Roussel Uclaf Dérivés de la cochicine et de la thiocolchicine et procédé de préparation
US4533675A (en) * 1984-04-17 1985-08-06 The United States Of America As Represented By The Department Of Health And Human Services Carbamates of colchicine for treatment of gout
EP0430968B1 (en) * 1988-05-02 1996-11-20 PHANOS TECHNOLOGIES, Inc. Compounds, compositions and method for binding bio-affecting substances to surface membranes of bio-particles
US5433675A (en) * 1993-11-29 1995-07-18 Excelermatic Inc. Traction roller transmission
IT1276996B1 (it) * 1995-06-27 1997-11-04 Indena Spa Derivati della colchicina, loro uso e formulazioni che li contengono
IT1283110B1 (it) * 1996-06-07 1998-04-07 Indena Spa Composti a scheletro colchicinico,loro uso come farmaci e composizioni che li contengono

Also Published As

Publication number Publication date
CZ303386B6 (cs) 2012-08-29
EP1263719B1 (en) 2009-07-22
HUP0300557A3 (en) 2004-08-30
AU2001248341B2 (en) 2005-01-27
ITMI20000554A0 (it) 2000-03-17
CN1418190A (zh) 2003-05-14
WO2001068597A1 (en) 2001-09-20
RU2257379C2 (ru) 2005-07-27
PL201575B1 (pl) 2009-04-30
RU2002124524A (ru) 2004-03-20
DE60139306D1 (de) 2009-09-03
NO20024354L (no) 2002-09-12
JP2003527371A (ja) 2003-09-16
EP1263719A1 (en) 2002-12-11
HU228790B1 (en) 2013-05-28
PL357375A1 (en) 2004-07-26
AU4834101A (en) 2001-09-24
ITMI20000554A1 (it) 2001-09-17
SK13102002A3 (sk) 2002-12-03
JP4614608B2 (ja) 2011-01-19
PT1263719E (pt) 2009-08-20
SK287108B6 (sk) 2009-12-07
HK1052168A1 (en) 2003-09-05
CA2403110C (en) 2009-12-15
IL151715A0 (en) 2003-04-10
ES2327386T3 (es) 2009-10-29
KR100761577B1 (ko) 2007-10-04
IL151715A (en) 2007-12-03
NO329428B1 (no) 2010-10-18
US6627774B2 (en) 2003-09-30
HUP0300557A2 (hu) 2003-07-28
IT1318401B1 (it) 2003-08-25
KR20020091123A (ko) 2002-12-05
NO20024354D0 (no) 2002-09-12
CN1169788C (zh) 2004-10-06
SI1263719T1 (sl) 2009-10-31
CA2403110A1 (en) 2001-09-20
US20030055111A1 (en) 2003-03-20

Similar Documents

Publication Publication Date Title
DK1329456T3 (da) Glucopyranosyloxybenzylbenzenderivater og medicinske sammensætninger indeholdende samme
IS7735A (is) Bensódíasepín afleiður og lyfjasamsetningar sem innihalda þær.
NO20024175D0 (no) Azetidinderivater, deres fremstilling og farmasöytiske forbindelser inneholdende de samme
ITTO20000779A0 (it) Composizioni farmaceutiche.
DK1112251T3 (da) Azetidinderivater, deres fremstilling og medikamenter indeholdende disse derivater
ITTO20010005A1 (it) Formulazione farmaceutica.
NO20011216D0 (no) Azetidinderivater, fremstilling og medisiner inneholdende disse
AR028204A1 (es) Composiciones farmaceuticas electrohiladas
NO20021401D0 (no) Konazolinforbindelser og farmasöytiske preparater inneholdende slike forbindelser
NO20044192L (no) 17alfa-alkyl-17beta-oksy-ostratriener og farmasoytiske preparater
ITMI20010748A0 (it) Composizioni farmaceutiche
NO20042084L (no) 6-hydroksyisoflavoner, derivater og legemidler som omfatter disse
DK199900176U3 (da) Paroxetinsalte, farmaceutisk præparat indeholdende disse og anvendelser deraf
HUP0302959A3 (en) Non-imidazole aryloxyalkylamines, pharmaceutical compositions containing them and their use
IS2841B (is) Samstæða hluta og lyfjasamsetningar
NO20026123L (no) Farmasöytiske sammensetninger
DK1560826T3 (da) Pyridopyrimidinonderivater, fremgangsmåde til fremstiling heraf og farmaceutiske sammensætninger indeholdende disse
NO20031095D0 (no) Farmasöytiske sammensetninger
NO20022022L (no) N-guanidinoalkylamider, deres fremstilling, deres anvendelse og farmasöytiske preparater omfattende disse
NO20030156D0 (no) Farmasöytiske sammensetninger og fremgangsmåter for anvendelse derav
DK1263719T3 (da) N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse.
DK1171444T3 (da) Pyridothienodiazepiner, fremgangsmåde til fremstilling af disse og farmaceutiske præparater indeholdende disse
DK1215213T3 (da) Bicylliske aminopyrazinonderivater, fremstilling deraf og farmaceutiske sammensætninger, som indeholder disse
NO20031841D0 (no) Triazolderivater og farmasöytiske preparater inneholdende disse
NO20034785D0 (no) Farmasöytiske kombinasjoner basert på pyridoindolon-derivater og anticancermidler