IS7735A - Bensódíasepín afleiður og lyfjasamsetningar sem innihalda þær. - Google Patents
Bensódíasepín afleiður og lyfjasamsetningar sem innihalda þær.Info
- Publication number
- IS7735A IS7735A IS7735A IS7735A IS7735A IS 7735 A IS7735 A IS 7735A IS 7735 A IS7735 A IS 7735A IS 7735 A IS7735 A IS 7735A IS 7735 A IS7735 A IS 7735A
- Authority
- IS
- Iceland
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- benzodiazepine derivatives
- benzodiazepine
- derivatives
- Prior art date
Links
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title 1
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0221923.6A GB0221923D0 (en) | 2002-09-20 | 2002-09-20 | Chemical compounds |
| GB0302078A GB0302078D0 (en) | 2003-01-29 | 2003-01-29 | Chemical compounds |
| PCT/GB2003/004050 WO2004026843A1 (en) | 2002-09-20 | 2003-09-22 | Benzodiazepine derivatives and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS7735A true IS7735A (is) | 2005-03-10 |
Family
ID=32031886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7735A IS7735A (is) | 2002-09-20 | 2005-03-10 | Bensódíasepín afleiður og lyfjasamsetningar sem innihalda þær. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7582624B2 (is) |
| EP (1) | EP1539716A1 (is) |
| JP (2) | JP4719466B2 (is) |
| KR (1) | KR101125899B1 (is) |
| AU (1) | AU2003267587B2 (is) |
| BR (1) | BR0314595A (is) |
| CA (1) | CA2499322C (is) |
| EA (1) | EA012387B1 (is) |
| IL (1) | IL167332A (is) |
| IS (1) | IS7735A (is) |
| MX (1) | MXPA05002871A (is) |
| NO (2) | NO20051908L (is) |
| NZ (2) | NZ570344A (is) |
| PL (1) | PL375860A1 (is) |
| WO (1) | WO2004026843A1 (is) |
| ZA (1) | ZA200502001B (is) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0406280D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Chemical compounds |
| GB0406279D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Therapeutic compounds |
| WO2005090319A1 (en) * | 2004-03-19 | 2005-09-29 | Arrow Therapeutics Limited | Process for preparing benzodiazepines |
| GB0406282D0 (en) * | 2004-03-19 | 2004-04-21 | Arrow Therapeutics Ltd | Therapeutic compounds |
| WO2006041970A2 (en) * | 2004-10-08 | 2006-04-20 | Abbott Biotechnology Ltd. | Treatment of respiratory syncytial virus (rsv) infection |
| EP1928465A1 (en) * | 2005-09-19 | 2008-06-11 | Arrow Therapeutics Limited | Benzodiazepine derivatives for treating hepatitis c infection |
| PE20080261A1 (es) | 2006-05-23 | 2008-04-18 | Novartis Ag | Sales y modificaciones del cristal de las mismas |
| BRPI0719096A2 (pt) * | 2006-11-21 | 2013-12-03 | Novartis Ag | Formulação parenteral estavel contendo uminibidor de rsv de uma estrutura de benzodiazepina |
| WO2010103306A1 (en) | 2009-03-10 | 2010-09-16 | Astrazeneca Uk Limited | Benzimidazole derivatives and their use as antivaral agents |
| TWI530489B (zh) | 2011-03-22 | 2016-04-21 | 必治妥美雅史谷比公司 | 雙（氟烷基）－１，４－苯二氮呯酮化合物 |
| CA2882088C (en) | 2012-08-23 | 2021-11-23 | Alios Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
| JP2015529250A (ja) | 2012-09-21 | 2015-10-05 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | フルオロアルキルジベンゾジアゼピノン化合物 |
| JP2015529251A (ja) | 2012-09-21 | 2015-10-05 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｎｏｔｃｈ阻害剤としての三環系複素環式化合物 |
| US9427442B2 (en) | 2012-09-21 | 2016-08-30 | Bristol-Myers Squibb Company | Fluoroalkyl and fluorocycloalkyl 1,4-benzodiazepinone compounds |
| US9242940B2 (en) | 2012-09-21 | 2016-01-26 | Bristol-Myers Squibb Company | N-substituted bis(fluoroalkyl)-1,4-benzodiazepinone compounds |
| EP2897944B1 (en) | 2012-09-21 | 2016-10-26 | Bristol-Myers Squibb Company | Substituted 1,5-benzodiazepinone compounds |
| WO2014047392A1 (en) | 2012-09-21 | 2014-03-27 | Bristol-Myers Squibb Company | Fluoroalkyl-1,4-benzodiazepinone compounds |
| TWI614238B (zh) * | 2012-09-21 | 2018-02-11 | 必治妥美雅史谷比公司 | 雙（氟烷基）－１，４－苯并二氮呯酮化合物及其前藥 |
| US9242941B2 (en) | 2012-09-21 | 2016-01-26 | Bristol-Myers Squibb Company | Alkyl, fluoroalkyl-1,4-benzodiazepinone compounds |
| JP2015531792A (ja) | 2012-09-21 | 2015-11-05 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | １，４−ベンゾジアゼピノン化合物のプロドラッグ |
| EP2981267A1 (en) | 2013-04-04 | 2016-02-10 | Bristol-Myers Squibb Company | Combination therapy for the treatment of proliferative diseases |
| MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
| GB201506448D0 (en) * | 2015-04-16 | 2015-06-03 | Univ Durham | An antimicrobial compound |
| JP7112324B2 (ja) | 2015-07-22 | 2022-08-03 | エナンタ ファーマシューティカルズ インコーポレイテッド | Ｒｓｖ阻害剤としてのベンゾジアゼピン誘導体 |
| US20170226129A1 (en) | 2016-01-15 | 2017-08-10 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as rsv inhibitors |
| US10080743B2 (en) | 2016-04-26 | 2018-09-25 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as FXR agonists and methods of use thereof |
| WO2017189652A1 (en) | 2016-04-26 | 2017-11-02 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| US10080742B2 (en) | 2016-04-26 | 2018-09-25 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as FXR agonists and methods of use thereof |
| GB201613942D0 (en) | 2016-08-15 | 2016-09-28 | Univ Of Durham The | An antimicrobial compound |
| WO2018081285A1 (en) | 2016-10-26 | 2018-05-03 | Enanta Pharmaceuticals, Inc. | Urea-containing isoxazole derivatives as fxr agonists and methods of use thereof |
| US10398706B2 (en) | 2017-01-06 | 2019-09-03 | Enanta Pharmaceuticals, Inc. | Heteroaryldiazepine derivatives as RSV inhibitors |
| JP7076459B2 (ja) | 2017-02-16 | 2022-05-27 | エナンタ ファーマシューティカルズ インコーポレイテッド | ベンゾジアゼピン誘導体の製造プロセス |
| US10752598B2 (en) | 2017-06-07 | 2020-08-25 | Enanta Pharmaceuticals, Inc. | Aryldiazepine derivatives as RSV inhibitors |
| WO2019006291A1 (en) | 2017-06-30 | 2019-01-03 | Enanta Pharmaceuticals, Inc. | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS |
| WO2019006295A1 (en) | 2017-06-30 | 2019-01-03 | Enanta Pharmaceuticals, Inc. | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS |
| US10881666B2 (en) | 2017-09-29 | 2021-01-05 | Enanta Pharmaceuticals, Inc. | Combination pharmaceutical agents as RSV inhibitors |
| WO2019094903A1 (en) | 2017-11-13 | 2019-05-16 | Enanta Pharmaceuticals, Inc. | Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives |
| WO2019094920A1 (en) * | 2017-11-13 | 2019-05-16 | Enanta Pharmaceuticals, Inc. | Azepin-2-one derivatives as rsv inhibitors |
| US10975094B2 (en) | 2018-04-11 | 2021-04-13 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| EP3941525A4 (en) | 2019-03-18 | 2022-12-07 | Enanta Pharmaceuticals, Inc. | BENZODIAZEPIN DERIVATIVES AS RSV INHIBITORS |
| WO2020210246A1 (en) | 2019-04-09 | 2020-10-15 | Enanta Pharmaceuticals, Inc, | Heterocyclic compounds as rsv inhibitors |
| GB201911944D0 (en) | 2019-08-20 | 2019-10-02 | Reviral Ltd | Pharmaceutical compounds |
| PH12022550783A1 (en) | 2019-10-04 | 2023-07-31 | Enanta Pharm Inc | Antiviral heterocyclic compounds |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| GB201915273D0 (en) * | 2019-10-22 | 2019-12-04 | Reviral Ltd | Pharmaceutical compounds |
| GB201915932D0 (en) | 2019-11-01 | 2019-12-18 | Reviral Ltd | Pharmaceutical compounds |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| GB202010408D0 (en) | 2020-07-07 | 2020-08-19 | Reviral Ltd | Pharmaceutical compounds |
| GB202010409D0 (en) | 2020-07-07 | 2020-08-19 | Reviral Ltd | Pharmaceutical compounds |
| US11534439B2 (en) | 2020-07-07 | 2022-12-27 | Enanta Pharmaceuticals, Inc. | Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors |
| US11945824B2 (en) | 2020-10-19 | 2024-04-02 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
| GB202102602D0 (en) | 2021-02-24 | 2021-04-07 | Reviral Ltd | Pharmaceutical compounds |
| WO2022182861A1 (en) | 2021-02-26 | 2022-09-01 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| AR129003A1 (es) | 2022-04-07 | 2024-07-03 | Enanta Pharm Inc | Compuestos heterocíclicos antivirales |
| US12162857B2 (en) | 2022-04-27 | 2024-12-10 | Enanta Pharmaceuticals, Inc. | Antiviral compounds |
| WO2024252355A1 (en) | 2023-06-08 | 2024-12-12 | Pfizer Inc. | Pediatric dosing regimens comprising a fusion inhibitor for the treatment of rsv |
| WO2025120500A1 (en) | 2023-12-06 | 2025-06-12 | Pfizer Inc. | Benzodiazepine compounds as n-protein inhibitors |
| WO2025153942A1 (en) | 2024-01-16 | 2025-07-24 | Pfizer Inc. | Benzodiazepine pyrazolo carboxamides as n-protein inhibitors |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL134421C (is) * | 1963-12-03 | |||
| CA1332410C (en) | 1984-06-26 | 1994-10-11 | Roger M. Freidinger | Benzodiazepine analogs |
| US4820834A (en) | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
| FR2641280B1 (fr) | 1988-12-29 | 1994-01-21 | Roussel Uclaf | Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments |
| US4628084A (en) * | 1986-01-02 | 1986-12-09 | Merck & Co., Inc. | Process for 3-acylamino benzodiazepines |
| CA2026856A1 (en) | 1989-10-05 | 1991-04-06 | Mark G. Bock | 3-substituted-1,4-benzodiazepines useful as oxytocin |
| IL96613A0 (en) | 1989-12-18 | 1991-09-16 | Merck & Co Inc | Pharmaceutical compositions containing benzodiazepine analogs |
| EP0475231A1 (en) | 1990-09-10 | 1992-03-18 | F. Hoffmann-La Roche Ag | Benzodiazepines |
| EP0491218A1 (en) * | 1990-12-17 | 1992-06-24 | F. Hoffmann-La Roche Ag | Benzodiazepinones |
| US5218115A (en) | 1991-04-10 | 1993-06-08 | Merck & Co., Inc. | Cholecystokinin antagonists |
| US5220017A (en) | 1991-04-10 | 1993-06-15 | Merck & Co., Inc. | Cholecystokinin antagonists |
| US5218114A (en) | 1991-04-10 | 1993-06-08 | Merck & Co., Inc. | Cholecystokinin antagonists |
| US5220018A (en) | 1991-04-10 | 1993-06-15 | Merck & Co., Inc. | Cholecystokinin antagonists |
| CA2071181A1 (en) | 1991-06-14 | 1992-12-15 | Roger M. Freidinger | Benzodiazepine analogs |
| EP0638560A4 (en) | 1991-10-11 | 1995-03-29 | Yoshitomi Pharmaceutical | MEDICINE FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND *. |
| US5428031A (en) | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
| US5550124A (en) | 1991-12-10 | 1996-08-27 | University Of Southern California | Use of peripheral-type benzodiazpine sites for treatment of CNS trauma or disease |
| GB9203790D0 (en) * | 1992-02-21 | 1992-04-08 | Merck Sharp & Dohme | Therapeutic agents |
| US5426185A (en) * | 1993-11-22 | 1995-06-20 | Merck & Co., Inc. | Antiarrhythmic benzodiazepines |
| FR2716195B1 (fr) | 1994-02-14 | 1996-06-21 | Sanofi Sa | Dérivés de 3-acylamino-5-phényl-1,4-benzodiazépin-2-one polysubstitués, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
| US5776930A (en) | 1996-06-28 | 1998-07-07 | Merck & Company, Inc. | Pharmaceutical preparation |
| AU3591697A (en) | 1996-07-02 | 1998-01-21 | Merck & Co., Inc. | Method for the treatment of preterm labor |
| KR100212435B1 (ko) | 1996-09-04 | 1999-08-02 | 이서봉 | 1,4-벤조디아제핀-2,5-디온 유도체 및 약학적으로 허용되는 그의 염 |
| WO1998018473A1 (en) | 1996-10-31 | 1998-05-07 | Merck & Co., Inc. | Benzodiazepine hydrazide derivatives as inhibitors of hiv integrase |
| US6100254A (en) | 1997-10-10 | 2000-08-08 | Board Of Regents, The University Of Texas System | Inhibitors of protein tyrosine kinases |
| JP2002525289A (ja) * | 1998-09-01 | 2002-08-13 | イノジェネティックス・ナムローゼ・フェンノートシャップ | アネキシンに結合するベンゾジアゼピンおよびベンゾチアゼピン誘導体ならびにｈｓｂｓａｇペプチド、それらの組成物ならびに使用 |
| FR2785803B1 (fr) | 1998-11-17 | 2005-03-25 | Sanofi Sa | Utilisation d'une substance se liant au recepteur peripherique des benzodiazepines dans le traitement des stress cutanes |
| EP1143946B1 (en) | 1999-04-30 | 2004-01-28 | The Regents Of The University Of Michigan | Use of benzodiazepines for treating autoimmune diseases induced by apoptosis |
| HK1046141B (zh) * | 1999-06-28 | 2006-09-22 | 詹森药业有限公司 | 呼吸系统的合胞体病毒复制抑制剂 |
| US6436971B2 (en) | 2000-02-09 | 2002-08-20 | Smithkline Beecham Corporation | Use of PDE 4-specific inhibitors to reduce the severity of a bacterial infection after a respiratory viral infection |
| MXPA02009755A (es) | 2000-04-03 | 2003-03-27 | Bristol Myers Squibb Pharma Co | Lactamas ciclicas como inhibidores de la produccion de proteina a-beta. |
| GB0012671D0 (en) | 2000-05-24 | 2000-07-19 | Merck Sharp & Dohme | Therapeutic agents |
| BR0106717A (pt) * | 2000-06-01 | 2002-04-16 | Bristol Myers Squibb Pharma Co | Compostos, composição farmacêutica e usos dos compostos de lactama inovadora |
| CN1179752C (zh) | 2000-08-16 | 2004-12-15 | 中国医学科学院药物研究所 | 含咪唑丙酰胺基的苯并二氮杂�类化合物以及制法和用途 |
| AU2002219846A1 (en) | 2000-11-16 | 2002-05-27 | Smith Kline Beecham Corporation | Novel use |
| SE0104250D0 (sv) * | 2001-12-14 | 2001-12-14 | Astrazeneca Ab | Heterocyclic compounds |
-
2003
- 2003-09-22 MX MXPA05002871A patent/MXPA05002871A/es active IP Right Grant
- 2003-09-22 CA CA2499322A patent/CA2499322C/en not_active Expired - Fee Related
- 2003-09-22 NZ NZ570344A patent/NZ570344A/en not_active IP Right Cessation
- 2003-09-22 US US10/528,250 patent/US7582624B2/en not_active Expired - Fee Related
- 2003-09-22 EA EA200500511A patent/EA012387B1/ru not_active IP Right Cessation
- 2003-09-22 JP JP2004537305A patent/JP4719466B2/ja not_active Expired - Fee Related
- 2003-09-22 AU AU2003267587A patent/AU2003267587B2/en not_active Ceased
- 2003-09-22 WO PCT/GB2003/004050 patent/WO2004026843A1/en active Application Filing
- 2003-09-22 KR KR1020057004751A patent/KR101125899B1/ko not_active Expired - Fee Related
- 2003-09-22 BR BR0314595-6A patent/BR0314595A/pt not_active IP Right Cessation
- 2003-09-22 EP EP03748279A patent/EP1539716A1/en not_active Withdrawn
- 2003-09-22 NZ NZ538870A patent/NZ538870A/en not_active IP Right Cessation
- 2003-09-22 PL PL03375860A patent/PL375860A1/xx unknown
-
2005
- 2005-03-09 ZA ZA2005/02001A patent/ZA200502001B/en unknown
- 2005-03-09 IL IL167332A patent/IL167332A/en not_active IP Right Cessation
- 2005-03-10 IS IS7735A patent/IS7735A/is unknown
- 2005-04-19 NO NO20051908A patent/NO20051908L/no not_active Application Discontinuation
-
2009
- 2009-06-02 US US12/476,797 patent/US8119630B2/en not_active Expired - Fee Related
-
2010
- 2010-12-01 JP JP2010268638A patent/JP5298103B2/ja not_active Expired - Fee Related
-
2014
- 2014-05-19 NO NO20140629A patent/NO20140629L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR101125899B1 (ko) | 2012-04-12 |
| CA2499322C (en) | 2012-04-24 |
| JP2011088907A (ja) | 2011-05-06 |
| AU2003267587A1 (en) | 2004-04-08 |
| EA200500511A1 (ru) | 2006-02-24 |
| AU2003267587B2 (en) | 2010-05-20 |
| IL167332A (en) | 2013-10-31 |
| US7582624B2 (en) | 2009-09-01 |
| EA012387B1 (ru) | 2009-10-30 |
| BR0314595A (pt) | 2005-08-09 |
| ZA200502001B (en) | 2006-05-31 |
| NO20140629L (no) | 2005-04-19 |
| NZ538870A (en) | 2007-04-27 |
| CA2499322A1 (en) | 2004-04-01 |
| JP2006503054A (ja) | 2006-01-26 |
| MXPA05002871A (es) | 2005-10-05 |
| US8119630B2 (en) | 2012-02-21 |
| NZ570344A (en) | 2010-04-30 |
| EP1539716A1 (en) | 2005-06-15 |
| PL375860A1 (en) | 2005-12-12 |
| WO2004026843A1 (en) | 2004-04-01 |
| US20060040923A1 (en) | 2006-02-23 |
| NO20051908L (no) | 2005-04-19 |
| US20100015063A1 (en) | 2010-01-21 |
| KR20050051664A (ko) | 2005-06-01 |
| JP5298103B2 (ja) | 2013-09-25 |
| JP4719466B2 (ja) | 2011-07-06 |
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