ITMI20000554A0 - Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono - Google Patents
Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengonoInfo
- Publication number
- ITMI20000554A0 ITMI20000554A0 IT2000MI000554A ITMI20000554A ITMI20000554A0 IT MI20000554 A0 ITMI20000554 A0 IT MI20000554A0 IT 2000MI000554 A IT2000MI000554 A IT 2000MI000554A IT MI20000554 A ITMI20000554 A IT MI20000554A IT MI20000554 A0 ITMI20000554 A0 IT MI20000554A0
- Authority
- IT
- Italy
- Prior art keywords
- desacetylthiocolchicine
- derivatives
- contain
- pharmaceutical compositions
- pharmaceutical
- Prior art date
Links
- NUNCOHUMTCDISK-AWEZNQCLSA-N (7s)-7-amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5h-benzo[a]heptalen-9-one Chemical class C1([C@@H](N)CC2)=CC(=O)C(SC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC NUNCOHUMTCDISK-AWEZNQCLSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (24)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI000554A IT1318401B1 (it) | 2000-03-17 | 2000-03-17 | Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono. |
| CA002403110A CA2403110C (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
| RU2002124524/04A RU2257379C2 (ru) | 2000-03-17 | 2001-03-12 | Производные n-деацетилтиоколхицина и содержащие их фармацевтические композиции |
| DE60139306T DE60139306D1 (de) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchin-derivate und diese enthaltende arzneimittel |
| DK01921326T DK1263719T3 (da) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse. |
| KR1020027011947A KR100761577B1 (ko) | 2000-03-17 | 2001-03-12 | Ｎ-데아세틸티오콜히친 유도체 및 그를 함유한 약제학적조성물 |
| CNB018064833A CN1169788C (zh) | 2000-03-17 | 2001-03-12 | N-脱乙酰基硫代秋水仙素衍生物及包含其的药物组合物 |
| SK1310-2002A SK287108B6 (sk) | 2000-03-17 | 2001-03-12 | N-Deacetyltiokolchicínové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie |
| HU0300557A HU228790B1 (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
| IL15171501A IL151715A0 (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
| JP2001567693A JP4614608B2 (ja) | 2000-03-17 | 2001-03-12 | Ｎ−デアセチルチオコルヒチン誘導体及びそれを含有する医薬組成物 |
| PL357375A PL201575B1 (pl) | 2000-03-17 | 2001-03-12 | Pochodne N-deacetylotiokolchicyny i kompozycje farmaceutyczne je zawierające |
| PT01921326T PT1263719E (pt) | 2000-03-17 | 2001-03-12 | Derivados de n-deacetiltiocolchicina e composições farmacêuticas contendo os mesmos |
| EP01921326A EP1263719B1 (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchine derivatives and pharmaceutical compositions containing them |
| ES01921326T ES2327386T3 (es) | 2000-03-17 | 2001-03-12 | Derivados de n-desacetiltiocolchicina y composiciones farmaceuticas que los contienen. |
| PCT/EP2001/002739 WO2001068597A1 (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
| CZ20023083A CZ303386B6 (cs) | 2000-03-17 | 2001-03-12 | N-deacetylthiokolchicinové deriváty |
| AU4834101A AU4834101A (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
| SI200130931T SI1263719T1 (sl) | 2000-03-17 | 2001-03-12 | Derivati n-deacetiltiokolhina in farmacevtski sestavki, ki jih vsebujejo |
| AU2001248341A AU2001248341B2 (en) | 2000-03-17 | 2001-03-12 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
| US10/210,035 US6627774B2 (en) | 2000-03-17 | 2002-08-02 | N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them |
| IL151715A IL151715A (en) | 2000-03-17 | 2002-09-12 | History of N-de-acetylthiocolciccin and pharmaceutical preparations containing them |
| NO20024354A NO329428B1 (no) | 2000-03-17 | 2002-09-12 | N-deacetyltiocolchicin-derivater, farmasoytiske sammensetninger inneholdende dem og anvendelse derav |
| HK03104265A HK1052168A1 (en) | 2000-03-17 | 2003-06-16 | N-deacetylthiocolchincine derivatives and pharmaceutical compositions containing them. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2000MI000554A IT1318401B1 (it) | 2000-03-17 | 2000-03-17 | Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI20000554A0 true ITMI20000554A0 (it) | 2000-03-17 |
| ITMI20000554A1 ITMI20000554A1 (it) | 2001-09-17 |
| IT1318401B1 IT1318401B1 (it) | 2003-08-25 |
Family
ID=11444502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT2000MI000554A IT1318401B1 (it) | 2000-03-17 | 2000-03-17 | Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6627774B2 (it) |
| EP (1) | EP1263719B1 (it) |
| JP (1) | JP4614608B2 (it) |
| KR (1) | KR100761577B1 (it) |
| CN (1) | CN1169788C (it) |
| AU (2) | AU4834101A (it) |
| CA (1) | CA2403110C (it) |
| CZ (1) | CZ303386B6 (it) |
| DE (1) | DE60139306D1 (it) |
| DK (1) | DK1263719T3 (it) |
| ES (1) | ES2327386T3 (it) |
| HK (1) | HK1052168A1 (it) |
| HU (1) | HU228790B1 (it) |
| IL (2) | IL151715A0 (it) |
| IT (1) | IT1318401B1 (it) |
| NO (1) | NO329428B1 (it) |
| PL (1) | PL201575B1 (it) |
| PT (1) | PT1263719E (it) |
| RU (1) | RU2257379C2 (it) |
| SI (1) | SI1263719T1 (it) |
| SK (1) | SK287108B6 (it) |
| WO (1) | WO2001068597A1 (it) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6825236B2 (en) * | 2003-04-14 | 2004-11-30 | California Pacific Medical Center | Colchicine derivatives |
| ITMI20040164A1 (it) * | 2004-02-03 | 2004-05-03 | Indena Spa | Derivati di n.deacetiltiocolchicina loro uso e formulazioni farmaceutiche che li contengono |
| EP2896412A1 (en) * | 2005-02-18 | 2015-07-22 | Abraxis BioScience, LLC | Drugs with improved hydrophobicity for incorporation in medical devices |
| DK2301531T3 (en) * | 2005-02-18 | 2018-07-30 | Abraxis Bioscience Llc | COMBINATIONS AND WAYS FOR ADMINISTRATING THERAPEUTIC SUBSTANCES AND COMBINATION THERAPY |
| WO2008027055A1 (en) * | 2006-08-31 | 2008-03-06 | Abraxis Bioscience, Llc | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
| US20080280987A1 (en) * | 2006-08-31 | 2008-11-13 | Desai Neil P | Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases |
| MX2011009452A (es) * | 2009-03-13 | 2011-11-29 | Abraxis Bioscience Llc | Terapia de combinacion con derivados tiocolchicina. |
| EP2924022A1 (en) * | 2014-03-27 | 2015-09-30 | INDENA S.p.A. | Amorphous form of a thiocolchicine derivative |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1359637A (fr) * | 1962-10-29 | 1964-04-30 | Roussel Uclaf | Dérivés de la cochicine et de la thiocolchicine et procédé de préparation |
| US4533675A (en) | 1984-04-17 | 1985-08-06 | The United States Of America As Represented By The Department Of Health And Human Services | Carbamates of colchicine for treatment of gout |
| DE68927479T2 (de) * | 1988-05-02 | 1997-04-03 | Phanos Tech Inc | Verbindungen, zusammensetzungen und verfahren zum binden von bio-affektions-substanzen an oberflächenmembranen von bioteilchen |
| US5433675A (en) * | 1993-11-29 | 1995-07-18 | Excelermatic Inc. | Traction roller transmission |
| IT1276996B1 (it) * | 1995-06-27 | 1997-11-04 | Indena Spa | Derivati della colchicina, loro uso e formulazioni che li contengono |
| IT1283110B1 (it) * | 1996-06-07 | 1998-04-07 | Indena Spa | Composti a scheletro colchicinico,loro uso come farmaci e composizioni che li contengono |
-
2000
- 2000-03-17 IT IT2000MI000554A patent/IT1318401B1/it active
-
2001
- 2001-03-12 AU AU4834101A patent/AU4834101A/xx active Pending
- 2001-03-12 EP EP01921326A patent/EP1263719B1/en not_active Expired - Lifetime
- 2001-03-12 KR KR1020027011947A patent/KR100761577B1/ko active IP Right Grant
- 2001-03-12 ES ES01921326T patent/ES2327386T3/es not_active Expired - Lifetime
- 2001-03-12 JP JP2001567693A patent/JP4614608B2/ja not_active Expired - Lifetime
- 2001-03-12 IL IL15171501A patent/IL151715A0/xx active IP Right Grant
- 2001-03-12 CA CA002403110A patent/CA2403110C/en not_active Expired - Lifetime
- 2001-03-12 CZ CZ20023083A patent/CZ303386B6/cs not_active IP Right Cessation
- 2001-03-12 RU RU2002124524/04A patent/RU2257379C2/ru active
- 2001-03-12 CN CNB018064833A patent/CN1169788C/zh not_active Expired - Lifetime
- 2001-03-12 AU AU2001248341A patent/AU2001248341B2/en not_active Expired
- 2001-03-12 PL PL357375A patent/PL201575B1/pl unknown
- 2001-03-12 HU HU0300557A patent/HU228790B1/hu unknown
- 2001-03-12 SI SI200130931T patent/SI1263719T1/sl unknown
- 2001-03-12 DK DK01921326T patent/DK1263719T3/da active
- 2001-03-12 SK SK1310-2002A patent/SK287108B6/sk not_active IP Right Cessation
- 2001-03-12 WO PCT/EP2001/002739 patent/WO2001068597A1/en active IP Right Grant
- 2001-03-12 DE DE60139306T patent/DE60139306D1/de not_active Expired - Lifetime
- 2001-03-12 PT PT01921326T patent/PT1263719E/pt unknown
-
2002
- 2002-08-02 US US10/210,035 patent/US6627774B2/en not_active Expired - Lifetime
- 2002-09-12 IL IL151715A patent/IL151715A/en unknown
- 2002-09-12 NO NO20024354A patent/NO329428B1/no not_active IP Right Cessation
-
2003
- 2003-06-16 HK HK03104265A patent/HK1052168A1/xx not_active IP Right Cessation
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