IS2425B - Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun - Google Patents

Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun

Info

Publication number
IS2425B
IS2425B IS7021A IS7021A IS2425B IS 2425 B IS2425 B IS 2425B IS 7021 A IS7021 A IS 7021A IS 7021 A IS7021 A IS 7021A IS 2425 B IS2425 B IS 2425B
Authority
IS
Iceland
Prior art keywords
production
heteroaryl derivatives
disorders
disorder
new heteroaryl
Prior art date
Application number
IS7021A
Other languages
English (en)
Other versions
IS7021A (is
Inventor
Rottländer Mario
Knud Moltzen Ejner
Mikkelsen Ivan
Ruhland Thomas
Andersen Kim
Krog-Jensen Christian
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of IS7021A publication Critical patent/IS7021A/is
Publication of IS2425B publication Critical patent/IS2425B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS7021A 2001-06-29 2003-11-10 Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun IS2425B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101036 2001-06-29
PCT/DK2002/000435 WO2003002556A1 (en) 2001-06-29 2002-06-27 Novel heteroaryl derivatives, their preparation and use

Publications (2)

Publication Number Publication Date
IS7021A IS7021A (is) 2003-11-10
IS2425B true IS2425B (is) 2008-10-15

Family

ID=8160598

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7021A IS2425B (is) 2001-06-29 2003-11-10 Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun

Country Status (26)

Country Link
US (2) US20040248883A1 (is)
EP (1) EP1399438B1 (is)
JP (1) JP2004535449A (is)
KR (1) KR20040019026A (is)
CN (1) CN1310909C (is)
AT (1) ATE312094T1 (is)
AU (1) AU2002344949B2 (is)
BG (1) BG108531A (is)
BR (1) BR0210401A (is)
CA (1) CA2451228A1 (is)
CZ (1) CZ2004156A3 (is)
DE (1) DE60207857T2 (is)
DK (1) DK1399438T3 (is)
EA (1) EA006203B1 (is)
ES (1) ES2252471T3 (is)
HU (1) HUP0400344A2 (is)
IL (1) IL158828A0 (is)
IS (1) IS2425B (is)
MX (1) MXPA03011769A (is)
NO (1) NO326514B1 (is)
NZ (1) NZ529460A (is)
PL (1) PL365249A1 (is)
SI (1) SI1399438T1 (is)
SK (1) SK652004A3 (is)
UA (1) UA75407C2 (is)
WO (1) WO2003002556A1 (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040019027A (ko) * 2001-06-29 2004-03-04 하. 룬트벡 아크티에 셀스카브 신규한 인돌 유도체
DE60231507D1 (de) 2001-07-20 2010-07-01 Psychogenics Inc Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
JP4741487B2 (ja) * 2003-07-02 2011-08-03 コーラス ファーマ，インコーポレイティド アズトレオナムｌ−リジン及びそれを調製するための方法
US7160888B2 (en) 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
JP2008521771A (ja) 2004-11-26 2008-06-26 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 改良された抗精神病活性および抗不安症活性を有するイソキサゾリン−インドール誘導体
CN102822167A (zh) 2010-01-04 2012-12-12 埃南蒂亚有限公司 用于制备利伐沙班的方法及其中间体
EP2559714B1 (en) 2010-04-12 2016-08-10 Lotte Chemical Corporation Method for preparing olefin-diene copolymer using transition metal compound including thiophene-condensed ring cyclopentadienyl ligand
KR100986301B1 (ko) 2010-04-12 2010-10-07 아주대학교산학협력단 테트라하이드로퀴놀린 유도체로부터 유래한 티오펜-축합고리 싸이클로펜타디에닐 4족 금속 화합물 및 이를 이용한 올레핀 중합
US8889581B2 (en) 2010-04-12 2014-11-18 Lotte Chemical Corporation Catalyst composition for olefin polymerization and preparation method for polyolefin using the same
JP5567209B2 (ja) 2010-04-12 2014-08-06 ロッテ ケミカル コーポレーション オレフィン重合用担持触媒およびこれを用いたポリオレフィンの製造方法
EP2559713B1 (en) 2010-04-12 2016-08-10 Lotte Chemical Corporation Method for preparing polypropylene using a transition metal compound containing thiophene-fused cyclopentadienyl ligands

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
KR20040019027A (ko) 2001-06-29 2004-03-04 하. 룬트벡 아크티에 셀스카브 신규한 인돌 유도체

Also Published As

Publication number Publication date
US7393845B2 (en) 2008-07-01
BR0210401A (pt) 2004-08-17
SK652004A3 (en) 2004-09-08
CN1310909C (zh) 2007-04-18
AU2002344949B2 (en) 2007-05-24
EP1399438A1 (en) 2004-03-24
CA2451228A1 (en) 2003-01-09
ATE312094T1 (de) 2005-12-15
SI1399438T1 (sl) 2006-04-30
EP1399438B1 (en) 2005-12-07
PL365249A1 (en) 2004-12-27
US20040248883A1 (en) 2004-12-09
DE60207857D1 (de) 2006-01-12
HUP0400344A2 (hu) 2004-09-28
HK1068622A1 (en) 2005-04-29
JP2004535449A (ja) 2004-11-25
UA75407C2 (en) 2006-04-17
CN1520410A (zh) 2004-08-11
EA200400102A1 (ru) 2004-04-29
NO326514B1 (no) 2008-12-22
WO2003002556A1 (en) 2003-01-09
EA006203B1 (ru) 2005-10-27
KR20040019026A (ko) 2004-03-04
IL158828A0 (en) 2004-05-12
IS7021A (is) 2003-11-10
DE60207857T2 (de) 2006-07-20
US20080027071A1 (en) 2008-01-31
DK1399438T3 (da) 2006-04-18
NZ529460A (en) 2005-09-30
CZ2004156A3 (cs) 2004-05-12
ES2252471T3 (es) 2006-05-16
BG108531A (bg) 2004-08-31
MXPA03011769A (es) 2004-04-02
NO20035673L (no) 2003-12-18
NO20035673D0 (no) 2003-12-18

Similar Documents

Publication Publication Date Title
RS20120158A3 (en) Phenyl-piperazine Derivatives As Serotonin Resorption Inhibitors
HUS2100028I1 (hu) ERBB I. típusú receptor tirozinkináz-gátló N4-fenil-kinazolin-4-amin származékok és rokon vegyületeik a hiperproliferatív betegségek kezelésére
CY1108464T1 (el) Παραγωγα 4-(2-φαινυλοσουλφανυλο-φαινυλο)πιπεριδινης, ως αναστολεις επαναπροσληψεως σεροτονινης
ATE347555T1 (de) 6-aminomorphinanderivate, herstellungsverfahren dafür und deren verwendung
IS7021A (is) Nýjar heteróarýlafleiður, framleiðsla þeirra og notkun
ATE282605T1 (de) 2-thio-subsituierte imidazolderivative und ihre verwendung in der pharmazie
CO5640133A2 (es) Derivados de 4-(2-feniloxifenil)-piperidina o 1,2,3,6-tetrahidropiridina como inhibidores de la recaptacion de la serotonina
DE60213576D1 (de) ANTIDEPRESSIVE AZAHETEROCYCLYLMETHYL-DERIVATE VON 2,3-DIHYDRO-1,4-DIOXINOi2,3-föCHINOXALIN
DE60201447D1 (de) Antidepressive azaheterocyclylmethylderivate von 7,8-dihydro-1,6,9-trioxa-3-azacyclopenta(a)naphthalin
MXPA03011766A (es) Novedosos derivados de indol.
EA200501579A1 (ru) Производные 4-(2-фенилсульфанилфенил)-1,2,3,6-тетрагидропиридина в качестве ингибиторов повторного поглощения серотонина
UA81469C2 (en) 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors
NO20053562L (no) Nye aminobenzofenonforbindelser
UA81472C2 (en) 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors
SE0301796D0 (sv) New use II
CA2521030A1 (en) 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors
SE0301798D0 (sv) New use IV