IS2309B - Ný hálfsmíðuð makrólíð sýklalyf úr asalíð röðunum - Google Patents

Ný hálfsmíðuð makrólíð sýklalyf úr asalíð röðunum

Info

Publication number
IS2309B
IS2309B IS7875A IS7875A IS2309B IS 2309 B IS2309 B IS 2309B IS 7875 A IS7875 A IS 7875A IS 7875 A IS7875 A IS 7875A IS 2309 B IS2309 B IS 2309B
Authority
IS
Iceland
Prior art keywords
constructed
macrolide antibiotics
new semi
azalide
series
Prior art date
Application number
IS7875A
Other languages
English (en)
Other versions
IS7875A (is
Inventor
Kujundzic Nedjeljko
Bukvic Krajacic Mirjana
Brajsa Karmen
Original Assignee
Pliva-Istrazivacki Institut D.O.O.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Istrazivacki Institut D.O.O. filed Critical Pliva-Istrazivacki Institut D.O.O.
Publication of IS7875A publication Critical patent/IS7875A/is
Publication of IS2309B publication Critical patent/IS2309B/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS7875A 2002-12-12 2005-05-31 Ný hálfsmíðuð makrólíð sýklalyf úr asalíð röðunum IS2309B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR20020991A HRP20020991A2 (en) 2002-12-12 2002-12-12 N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
PCT/HR2003/000062 WO2004052904A2 (en) 2002-12-12 2003-12-10 Novel semisynthetic macrolide antibiotics of the azalide series

Publications (2)

Publication Number Publication Date
IS7875A IS7875A (is) 2005-05-31
IS2309B true IS2309B (is) 2007-10-15

Family

ID=32500425

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7875A IS2309B (is) 2002-12-12 2005-05-31 Ný hálfsmíðuð makrólíð sýklalyf úr asalíð röðunum

Country Status (25)

Country Link
US (1) US7342000B2 (is)
EP (1) EP1585753B1 (is)
JP (1) JP2006510660A (is)
KR (1) KR20050085555A (is)
CN (1) CN100335489C (is)
AR (1) AR042351A1 (is)
AT (1) ATE327999T1 (is)
AU (1) AU2003285599A1 (is)
BR (1) BR0316569A (is)
CA (1) CA2509599A1 (is)
CL (1) CL2003002585A1 (is)
CO (1) CO5640139A2 (is)
CY (1) CY1106321T1 (is)
DE (1) DE60305741T2 (is)
DK (1) DK1585753T3 (is)
ES (1) ES2266883T3 (is)
HK (1) HK1086273A1 (is)
HR (1) HRP20020991A2 (is)
IS (1) IS2309B (is)
MX (1) MXPA05006220A (is)
PL (1) PL377322A1 (is)
PT (1) PT1585753E (is)
RS (1) RS80204A (is)
RU (1) RU2328503C2 (is)
WO (1) WO2004052904A2 (is)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
WO2006085228A2 (en) * 2005-01-14 2006-08-17 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. 9a-carbamoyl-y-aminopropyl and 9a-thiocarbamoyl-y-aminopropyl-azalides with antimalarial activity
EP1835921B1 (en) * 2005-01-14 2010-08-18 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. 9a-carbamoyl-y-aminopropyl- and 9a-thiocarbamoyl-y-aminopropyl-azalides with antimalarial activity
EP2012776A2 (en) * 2006-05-03 2009-01-14 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. 9a-substituted azalides

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
FR2473525A1 (fr) 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
BE892397A (nl) 1982-03-08 1982-07-01 Marchand Paul Wereldwijde draadloze telefonie voor 10 miljard abonnees
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4492688A (en) * 1983-11-25 1985-01-08 Pfizer Inc. Antibacterial cyclic ethers of 9-deoxo-9a-aza-9a-homoerythromycin A and intermediates therefor
US4464527A (en) 1983-06-30 1984-08-07 Pfizer Inc. Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
MX13723A (es) 1987-11-10 1993-05-01 Pfizer Procedimiento para preparar derivados de 9-desoxo-9a-alil- y propargil-9a-aza-9a-homoeritromicina a
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
WO1997035590A1 (en) 1996-03-25 1997-10-02 Platt Chris E 10-aza-9-deoxo-11-deoxy-erythromycin a and derivatives combined with sulfisoxazole
HRP990130B1 (en) * 1999-05-03 2004-06-30 Pliva D D HALOGEN DERIVATIVES 9a-N-(N'-ARYLCARBAMOYL)- AND 9a-N-(N'-ARYLTHIOCARBAMOYL)-9-DEOXO-9a-AZA-9a OF HOMOERYTHROMYCIN A
CN1492874A (zh) * 2000-12-21 2004-04-28 大环内酯
HRP20010146B1 (en) 2001-02-28 2005-10-31 Pliva D.D. 9a-N-(N'-(PHENYLSULFONYL)CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMYCIN A AND OF 5-O-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHRONOLIDE A
HRP20020886A2 (en) 2002-11-11 2005-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. SUBSTITUTED 9a-N-[N'-(BENZENSULFONYL)CARBAMOYL-γ-AMINOPROPYL) AND 9a-N(N' -(?-CYANOETHIL)-N' -(b
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A

Also Published As

Publication number Publication date
US20060252709A1 (en) 2006-11-09
CO5640139A2 (es) 2006-05-31
RU2328503C2 (ru) 2008-07-10
MXPA05006220A (es) 2005-11-17
CL2003002585A1 (es) 2005-01-28
AU2003285599A1 (en) 2004-06-30
WO2004052904A3 (en) 2004-09-02
PL377322A1 (pl) 2006-01-23
DE60305741D1 (de) 2006-07-06
PT1585753E (pt) 2006-08-31
CN100335489C (zh) 2007-09-05
BR0316569A (pt) 2005-10-04
US7342000B2 (en) 2008-03-11
EP1585753B1 (en) 2006-05-31
RU2005121892A (ru) 2006-01-20
DE60305741T2 (de) 2007-06-14
ES2266883T3 (es) 2007-03-01
DK1585753T3 (da) 2006-10-02
HRP20020991A2 (en) 2005-02-28
HK1086273A1 (en) 2006-09-15
KR20050085555A (ko) 2005-08-29
CN1726222A (zh) 2006-01-25
ATE327999T1 (de) 2006-06-15
WO2004052904A2 (en) 2004-06-24
IS7875A (is) 2005-05-31
RS80204A (en) 2006-12-15
JP2006510660A (ja) 2006-03-30
CY1106321T1 (el) 2011-10-12
AU2003285599A8 (en) 2004-06-30
EP1585753A2 (en) 2005-10-19
CA2509599A1 (en) 2004-06-24
AR042351A1 (es) 2005-06-15

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