IS2274B - Aðferð til að búa til kamptóþesín afleiður - Google Patents
Aðferð til að búa til kamptóþesín afleiðurInfo
- Publication number
- IS2274B IS2274B IS4730A IS4730A IS2274B IS 2274 B IS2274 B IS 2274B IS 4730 A IS4730 A IS 4730A IS 4730 A IS4730 A IS 4730A IS 2274 B IS2274 B IS 2274B
- Authority
- IS
- Iceland
- Prior art keywords
- pct
- date
- camptothecin derivatives
- sec
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US613895P | 1995-11-02 | 1995-11-02 | |
PCT/US1996/017574 WO1997016454A1 (en) | 1995-11-02 | 1996-11-01 | Method for preparing camptothecin derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IS4730A IS4730A (is) | 1998-04-29 |
IS2274B true IS2274B (is) | 2007-09-15 |
Family
ID=21719492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS4730A IS2274B (is) | 1995-11-02 | 1998-04-29 | Aðferð til að búa til kamptóþesín afleiður |
Country Status (17)
Country | Link |
---|---|
US (2) | US6143891A (is) |
EP (1) | EP0876373B1 (is) |
JP (1) | JP3499246B2 (is) |
AT (1) | ATE301659T1 (is) |
AU (1) | AU717315B2 (is) |
CA (1) | CA2236420A1 (is) |
CZ (1) | CZ133898A3 (is) |
DE (1) | DE69635057T2 (is) |
EA (1) | EA001400B1 (is) |
ES (1) | ES2247606T3 (is) |
HU (1) | HUP9802407A3 (is) |
IL (1) | IL124287A (is) |
IS (1) | IS2274B (is) |
NO (1) | NO324308B1 (is) |
NZ (1) | NZ322318A (is) |
PL (1) | PL186540B1 (is) |
WO (1) | WO1997016454A1 (is) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5491237A (en) * | 1994-05-03 | 1996-02-13 | Glaxo Wellcome Inc. | Intermediates in pharmaceutical camptothecin preparation |
US6716982B2 (en) | 1995-11-02 | 2004-04-06 | Osi Pharmaceuticals, Inc. | Method for preparing camptothecin derivatives |
US6559309B2 (en) | 1996-11-01 | 2003-05-06 | Osi Pharmaceuticals, Inc. | Preparation of a camptothecin derivative by intramolecular cyclisation |
US6288072B1 (en) * | 1999-12-29 | 2001-09-11 | Monroe E. Wall | Camptothecin β-alanine esters with topoisomerase I inhibition |
AR035684A1 (es) | 2001-02-21 | 2004-06-23 | Yakult Honsha Kk | Procedimiento para preparar 2'-amino-5'-hidroxipropiofenona, uso de la misma para la preparacion de analogos de camptotecina, procedimiento para prepararlos, compuestos intermediarios, procedimiento para preparar una cetona triciclica utilizada en la sintesis de analogos de camptotecina |
WO2003068778A1 (en) * | 2002-02-18 | 2003-08-21 | Dr. Reddy's Laboratories Limited | A process for the preparation of 10-hydroxy-9-n,n-dimethylaminomethyl-5-(2'-fluoroethoxy)-20(s)-camptothecin hydrochloride |
US6593334B1 (en) | 2002-05-02 | 2003-07-15 | The University Of North Carolina At Chapel Hill | Camptothecin-taxoid conjugates as antimitotic and antitumor agents |
US7067666B2 (en) * | 2003-06-27 | 2006-06-27 | Research Triangle Institute | 7-substituted camptothecin and camptothecin analogs and methods for producing the same |
AU2005244768B2 (en) | 2004-04-27 | 2011-06-09 | Wellstat Biologics Corporation | Cancer treatment using viruses and camptothecins |
ATE540698T1 (de) | 2005-07-14 | 2012-01-15 | Wellstat Biologics Corp | Krebsbehandlung mit viren, fluoropyrimidinen und camptothecinen |
CN103288842B (zh) * | 2012-02-24 | 2016-01-13 | 中国人民解放军第二军医大学 | 氟取代e环喜树碱类似物及其作为药物的用途 |
CN108135917B (zh) | 2015-09-25 | 2021-07-09 | Zy医疗 | 基于包含多糖-维生素缀合物的颗粒的药物制剂 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8940491A (en) * | 1990-10-31 | 1992-05-26 | Smithkline Beecham Corporation | Substituted indolizino(1,2-b)quinolinones |
AU3611093A (en) * | 1992-02-21 | 1993-09-13 | Smithkline Beecham Corporation | Substituted furo(3',4':6,7)indolizino(1,2-b)quinolinones |
-
1996
- 1996-11-01 JP JP51758897A patent/JP3499246B2/ja not_active Expired - Fee Related
- 1996-11-01 ES ES96938728T patent/ES2247606T3/es not_active Expired - Lifetime
- 1996-11-01 PL PL96326869A patent/PL186540B1/pl not_active IP Right Cessation
- 1996-11-01 EA EA199800354A patent/EA001400B1/ru not_active IP Right Cessation
- 1996-11-01 AT AT96938728T patent/ATE301659T1/de not_active IP Right Cessation
- 1996-11-01 US US09/068,185 patent/US6143891A/en not_active Expired - Fee Related
- 1996-11-01 HU HU9802407A patent/HUP9802407A3/hu unknown
- 1996-11-01 EP EP96938728A patent/EP0876373B1/en not_active Expired - Lifetime
- 1996-11-01 AU AU76038/96A patent/AU717315B2/en not_active Ceased
- 1996-11-01 CZ CZ981338A patent/CZ133898A3/cs unknown
- 1996-11-01 CA CA002236420A patent/CA2236420A1/en not_active Abandoned
- 1996-11-01 NZ NZ322318A patent/NZ322318A/xx unknown
- 1996-11-01 IL IL12428796A patent/IL124287A/en not_active IP Right Cessation
- 1996-11-01 WO PCT/US1996/017574 patent/WO1997016454A1/en not_active Application Discontinuation
- 1996-11-01 DE DE69635057T patent/DE69635057T2/de not_active Expired - Fee Related
-
1998
- 1998-04-29 IS IS4730A patent/IS2274B/is unknown
- 1998-04-30 NO NO19981970A patent/NO324308B1/no unknown
-
2000
- 2000-08-15 US US09/638,945 patent/US6284891B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2236420A1 (en) | 1997-05-09 |
ES2247606T3 (es) | 2006-03-01 |
IS4730A (is) | 1998-04-29 |
EA001400B1 (ru) | 2001-02-26 |
PL186540B1 (pl) | 2004-01-30 |
NZ322318A (en) | 2000-01-28 |
JPH11515028A (ja) | 1999-12-21 |
EA199800354A1 (ru) | 1999-02-25 |
EP0876373B1 (en) | 2005-08-10 |
NO981970D0 (no) | 1998-04-30 |
NO981970L (no) | 1998-06-30 |
EP0876373A1 (en) | 1998-11-11 |
ATE301659T1 (de) | 2005-08-15 |
IL124287A (en) | 2004-06-01 |
NO324308B1 (no) | 2007-09-24 |
DE69635057T2 (de) | 2006-06-01 |
US6143891A (en) | 2000-11-07 |
AU7603896A (en) | 1997-05-22 |
CZ133898A3 (cs) | 1998-08-12 |
PL326869A1 (en) | 1998-10-26 |
HUP9802407A1 (hu) | 1999-04-28 |
DE69635057D1 (de) | 2005-09-15 |
WO1997016454A1 (en) | 1997-05-09 |
AU717315B2 (en) | 2000-03-23 |
US6284891B1 (en) | 2001-09-04 |
JP3499246B2 (ja) | 2004-02-23 |
HUP9802407A3 (en) | 2000-01-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0835257T3 (da) | Mellemprodukter og fremgangsmåde til fremstilling af camptothecin-derivater (CPT-11) og beslægtede forbindelser | |
DE69711391D1 (de) | Verbessertes verfahren zum herstellen von geschützten 3,4-dihydroxybuttersäure estern | |
HUP9701048A2 (hu) | Új eljárás sildenafil előállítására és a felhasznált új köztitermékek | |
NO985377L (no) | FremgangsmÕte for Õ fremstille polyalkenaminer | |
DK0696281T3 (da) | Hidtil ukendte 5-pyrrolyl-2-pyridylmethylsulfinylbenzimidazolderivater | |
HU9601857D0 (en) | New benzyl-piperidine- or -tetrahydro-pyridine derivatives and processes for producing them | |
IL112622A (en) | Iminoalkylamino or aminoalkylideneamino camptothecin derivatives, process for their preparation and pharmaceutical compositions containing them | |
IS2274B (is) | Aðferð til að búa til kamptóþesín afleiður | |
DE69627166D1 (de) | Verfahren zur herstellung von 2-chlor-5-chlomethyl-thiazol-derivaten | |
GR1000156B (el) | ΜΕΘΟΔΟΣ ΠΑΡΑΣΚΕΥΗΣ ΝΕΩΝ ΠΑΡΑΓΩΓΩΝ ΤΡΙΚΥΚΛΙΚΩΝ ΑΜΙΝΩΝ ΤΗΣ ΤΕΤΡΑΥΔΡΟ-5,6,7,8ΝΑΦΘΟ[2,3b] ΔΙΥΔΡΟ-2,3 ΦΟΥΡΑΝΗΣ & ΤΗΣ ΤΕΤΡΑΥΔΡΟ-6,7,8,9 5Η-ΒΕΝΖΟΚΥΚΛΟΕΠΤΑ[2,3Β] ΔΙΥΔΡΟ-2,3 ΦΟΥΡΑΝΗΣ. | |
BR9610175A (pt) | Composto processo de preparação do composto composição farmacêutica e utilização do composto | |
HU9503099D0 (en) | New piperazinyl-alkylthio-pyrimidine derivatives, pharmaceutical compositions containing them, and process for producing the active components | |
ATE188694T1 (de) | Verfahren zur herstellung von benzopyranderivaten | |
DE69513408D1 (de) | Ein verbessertes verfahren für die herstellung von seitenketten-derivaten von cyclohexapeptidyl-lipopeptiden | |
EE9700292A (et) | Asendatud fenüülamidiinid, neid ühendeid sisaldavad ravimid ja meetod nende valmistamiseks | |
ATE215071T1 (de) | Verfahren zur herstellung von prostaglandin e1 | |
DE3483011D1 (de) | Substituierte alkylamino-derivate von 6,11-dihydro-11-oxo-dibenz(b,e)-oxepin, verfahren zu ihrer herstellung, ihre zwischenprodukte und ihre verwendung als arzneimittel. | |
DK1070082T3 (da) | Fremgangsmåde til fremstilling af 4,4-dimethyl-5alfa-cholesta-8,14,24-trien-3beta-ol og mellemprodukter i fremgangsmåden (I) | |
ATE135350T1 (de) | Verfahren zur herstellung von 2-amino-7- nitrobenzothiazolen |