NO981970L - FremgangsmÕte for fremstilling av Camptothecin-derivater - Google Patents

FremgangsmÕte for fremstilling av Camptothecin-derivater

Info

Publication number
NO981970L
NO981970L NO981970A NO981970A NO981970L NO 981970 L NO981970 L NO 981970L NO 981970 A NO981970 A NO 981970A NO 981970 A NO981970 A NO 981970A NO 981970 L NO981970 L NO 981970L
Authority
NO
Norway
Prior art keywords
pct
date
camptothecin derivatives
preparing camptothecin
sec
Prior art date
Application number
NO981970A
Other languages
English (en)
Other versions
NO981970D0 (no
NO324308B1 (no
Inventor
Francis Gerard Fang
Shiping Xie
Original Assignee
Glaxo Wellcome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Inc filed Critical Glaxo Wellcome Inc
Publication of NO981970D0 publication Critical patent/NO981970D0/no
Publication of NO981970L publication Critical patent/NO981970L/no
Publication of NO324308B1 publication Critical patent/NO324308B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO19981970A 1995-11-02 1998-04-30 Fremgangsmate for fremstilling av Camptothecin-derivater, samt produkter av og mellomprodukter for slike forbindelser NO324308B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US613895P 1995-11-02 1995-11-02
PCT/US1996/017574 WO1997016454A1 (en) 1995-11-02 1996-11-01 Method for preparing camptothecin derivatives

Publications (3)

Publication Number Publication Date
NO981970D0 NO981970D0 (no) 1998-04-30
NO981970L true NO981970L (no) 1998-06-30
NO324308B1 NO324308B1 (no) 2007-09-24

Family

ID=21719492

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19981970A NO324308B1 (no) 1995-11-02 1998-04-30 Fremgangsmate for fremstilling av Camptothecin-derivater, samt produkter av og mellomprodukter for slike forbindelser

Country Status (17)

Country Link
US (2) US6143891A (no)
EP (1) EP0876373B1 (no)
JP (1) JP3499246B2 (no)
AT (1) ATE301659T1 (no)
AU (1) AU717315B2 (no)
CA (1) CA2236420A1 (no)
CZ (1) CZ133898A3 (no)
DE (1) DE69635057T2 (no)
EA (1) EA001400B1 (no)
ES (1) ES2247606T3 (no)
HU (1) HUP9802407A3 (no)
IL (1) IL124287A (no)
IS (1) IS2274B (no)
NO (1) NO324308B1 (no)
NZ (1) NZ322318A (no)
PL (1) PL186540B1 (no)
WO (1) WO1997016454A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5491237A (en) * 1994-05-03 1996-02-13 Glaxo Wellcome Inc. Intermediates in pharmaceutical camptothecin preparation
US6716982B2 (en) 1995-11-02 2004-04-06 Osi Pharmaceuticals, Inc. Method for preparing camptothecin derivatives
US6559309B2 (en) 1996-11-01 2003-05-06 Osi Pharmaceuticals, Inc. Preparation of a camptothecin derivative by intramolecular cyclisation
US6288072B1 (en) * 1999-12-29 2001-09-11 Monroe E. Wall Camptothecin β-alanine esters with topoisomerase I inhibition
AR035684A1 (es) 2001-02-21 2004-06-23 Yakult Honsha Kk Procedimiento para preparar 2'-amino-5'-hidroxipropiofenona, uso de la misma para la preparacion de analogos de camptotecina, procedimiento para prepararlos, compuestos intermediarios, procedimiento para preparar una cetona triciclica utilizada en la sintesis de analogos de camptotecina
WO2003068778A1 (en) * 2002-02-18 2003-08-21 Dr. Reddy's Laboratories Limited A process for the preparation of 10-hydroxy-9-n,n-dimethylaminomethyl-5-(2'-fluoroethoxy)-20(s)-camptothecin hydrochloride
US6593334B1 (en) 2002-05-02 2003-07-15 The University Of North Carolina At Chapel Hill Camptothecin-taxoid conjugates as antimitotic and antitumor agents
US7067666B2 (en) * 2003-06-27 2006-06-27 Research Triangle Institute 7-substituted camptothecin and camptothecin analogs and methods for producing the same
AU2005244768B2 (en) 2004-04-27 2011-06-09 Wellstat Biologics Corporation Cancer treatment using viruses and camptothecins
ATE540698T1 (de) 2005-07-14 2012-01-15 Wellstat Biologics Corp Krebsbehandlung mit viren, fluoropyrimidinen und camptothecinen
CN103288842B (zh) * 2012-02-24 2016-01-13 中国人民解放军第二军医大学 氟取代e环喜树碱类似物及其作为药物的用途
CN108135917B (zh) 2015-09-25 2021-07-09 Zy医疗 基于包含多糖-维生素缀合物的颗粒的药物制剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8940491A (en) * 1990-10-31 1992-05-26 Smithkline Beecham Corporation Substituted indolizino(1,2-b)quinolinones
AU3611093A (en) * 1992-02-21 1993-09-13 Smithkline Beecham Corporation Substituted furo(3',4':6,7)indolizino(1,2-b)quinolinones

Also Published As

Publication number Publication date
CA2236420A1 (en) 1997-05-09
IS2274B (is) 2007-09-15
ES2247606T3 (es) 2006-03-01
IS4730A (is) 1998-04-29
EA001400B1 (ru) 2001-02-26
PL186540B1 (pl) 2004-01-30
NZ322318A (en) 2000-01-28
JPH11515028A (ja) 1999-12-21
EA199800354A1 (ru) 1999-02-25
EP0876373B1 (en) 2005-08-10
NO981970D0 (no) 1998-04-30
EP0876373A1 (en) 1998-11-11
ATE301659T1 (de) 2005-08-15
IL124287A (en) 2004-06-01
NO324308B1 (no) 2007-09-24
DE69635057T2 (de) 2006-06-01
US6143891A (en) 2000-11-07
AU7603896A (en) 1997-05-22
CZ133898A3 (cs) 1998-08-12
PL326869A1 (en) 1998-10-26
HUP9802407A1 (hu) 1999-04-28
DE69635057D1 (de) 2005-09-15
WO1997016454A1 (en) 1997-05-09
AU717315B2 (en) 2000-03-23
US6284891B1 (en) 2001-09-04
JP3499246B2 (ja) 2004-02-23
HUP9802407A3 (en) 2000-01-28

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