IN2015MN00139A - - Google Patents

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Publication number
IN2015MN00139A
IN2015MN00139A IN139MUN2015A IN2015MN00139A IN 2015MN00139 A IN2015MN00139 A IN 2015MN00139A IN 139MUN2015 A IN139MUN2015 A IN 139MUN2015A IN 2015MN00139 A IN2015MN00139 A IN 2015MN00139A
Authority
IN
India
Prior art keywords
protein
fragments
present
hetero dimeric
immunoglobulinvariants
Prior art date
Application number
Other languages
English (en)
Inventor
Stanislas Blein
Fabrizio Comper
Romain Ollier
Paul Wassmann
Original Assignee
Glenmark Pharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals Sa filed Critical Glenmark Pharmaceuticals Sa
Publication of IN2015MN00139A publication Critical patent/IN2015MN00139A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/522CH1 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/524CH2 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/526CH3 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IN139MUN2015 2012-09-25 2013-09-25 IN2015MN00139A (forum.php)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261705278P 2012-09-25 2012-09-25
PCT/EP2013/069989 WO2014049003A1 (en) 2012-09-25 2013-09-25 Purification of hetero-dimeric immunoglobulins

Publications (1)

Publication Number Publication Date
IN2015MN00139A true IN2015MN00139A (forum.php) 2015-10-16

Family

ID=49237223

Family Applications (1)

Application Number Title Priority Date Filing Date
IN139MUN2015 IN2015MN00139A (forum.php) 2012-09-25 2013-09-25

Country Status (11)

Country Link
US (2) US20150239991A1 (forum.php)
EP (2) EP2900696A1 (forum.php)
JP (5) JP2015529236A (forum.php)
KR (1) KR20150076172A (forum.php)
CN (1) CN104968685A (forum.php)
AU (2) AU2013322710A1 (forum.php)
CA (2) CA2886036A1 (forum.php)
HK (1) HK1215950A1 (forum.php)
IL (2) IL237872B (forum.php)
IN (1) IN2015MN00139A (forum.php)
WO (1) WO2014049003A1 (forum.php)

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Also Published As

Publication number Publication date
AU2013322710A2 (en) 2015-05-07
KR20150076172A (ko) 2015-07-06
EP2900696A1 (en) 2015-08-05
IL237872A0 (en) 2015-05-31
HK1215950A1 (zh) 2016-09-30
CA2886036A1 (en) 2014-04-03
JP6856610B2 (ja) 2021-04-07
AU2013322710A1 (en) 2015-04-16
JP2018104444A (ja) 2018-07-05
AU2018204314B2 (en) 2020-05-14
IL237872B (en) 2019-09-26
IL269207A (en) 2019-11-28
CN104968685A (zh) 2015-10-07
EP3401337A1 (en) 2018-11-14
IL269207B (en) 2022-02-01
JP2019073512A (ja) 2019-05-16
WO2014049003A1 (en) 2014-04-03
CA3061557A1 (en) 2014-04-03
US20200010568A1 (en) 2020-01-09
JP2022116326A (ja) 2022-08-09
AU2018204314A1 (en) 2018-07-05
JP2020105203A (ja) 2020-07-09
JP2015529236A (ja) 2015-10-05
US20150239991A1 (en) 2015-08-27

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