IN2015DN03327A - - Google Patents

Info

Publication number
IN2015DN03327A
IN2015DN03327A IN3327DEN2015A IN2015DN03327A IN 2015DN03327 A IN2015DN03327 A IN 2015DN03327A IN 3327DEN2015 A IN3327DEN2015 A IN 3327DEN2015A IN 2015DN03327 A IN2015DN03327 A IN 2015DN03327A
Authority
IN
India
Prior art keywords
processes
preparation
pharmaceutical compositions
relates
viral infections
Prior art date
Application number
Other languages
English (en)
Inventor
Vincent Gembus
Philippe Jubault
Christophe Hoarau
Vincent Levacher
Jean-François Bonfanti
Gowan David Graig Mc
Jérôme Emile Georges Guillemont
Original Assignee
Centre Nat Rech Scient
Univ Rouen
Inst Nat Sciences Appliq
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Univ Rouen, Inst Nat Sciences Appliq filed Critical Centre Nat Rech Scient
Publication of IN2015DN03327A publication Critical patent/IN2015DN03327A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075Two hetero atoms, in positions 3 and 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
IN3327DEN2015 2012-10-01 2013-10-01 IN2015DN03327A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12306196.2A EP2712866A1 (fr) 2012-10-01 2012-10-01 Dérivés de 1,2,4-triazine pour le traitement d'infections virales
PCT/EP2013/070488 WO2014053516A1 (fr) 2012-10-01 2013-10-01 Dérivés 1,2,4-triazines pour le traitement d'infections virales

Publications (1)

Publication Number Publication Date
IN2015DN03327A true IN2015DN03327A (fr) 2015-10-09

Family

ID=46982496

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3327DEN2015 IN2015DN03327A (fr) 2012-10-01 2013-10-01

Country Status (22)

Country Link
US (1) US9416114B2 (fr)
EP (2) EP2712866A1 (fr)
JP (1) JP6298998B2 (fr)
KR (1) KR102138393B1 (fr)
CN (1) CN104812747B (fr)
AU (1) AU2013326579B2 (fr)
BR (1) BR112015007310B1 (fr)
CA (1) CA2886630C (fr)
CL (1) CL2015000787A1 (fr)
EA (1) EA026236B1 (fr)
ES (1) ES2616496T3 (fr)
HK (1) HK1208223A1 (fr)
IL (1) IL237871A (fr)
IN (1) IN2015DN03327A (fr)
MX (1) MX348229B (fr)
MY (1) MY182558A (fr)
NZ (1) NZ706354A (fr)
PH (1) PH12015500724B1 (fr)
SG (1) SG11201502522WA (fr)
UA (1) UA114644C2 (fr)
WO (1) WO2014053516A1 (fr)
ZA (1) ZA201502240B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS60191B1 (sr) 2011-04-08 2020-06-30 Janssen Sciences Ireland Unlimited Co Derivati pirimidina za tretman virusnih infekcija
AU2012334127B2 (en) 2011-11-09 2017-05-18 Janssen Sciences Ireland Uc Purine derivatives for the treatment of viral infections
HUE030685T2 (en) 2012-07-13 2017-05-29 Janssen Sciences Ireland Uc Macrocyclic purines for treating viral infections
TR201807076T4 (tr) 2012-10-10 2018-06-21 Janssen Sciences Ireland Uc Viral enfeksiyonların ve diğer hastalıkların tedavisine yönelik pirolo[3,2-d]pirimidin derivatları.
EP2925729B1 (fr) 2012-11-16 2017-10-18 Janssen Sciences Ireland UC Dérivés de 2-amino-quinazoline substitué hétérocycliques pour le traitement d'infections virales
KR102300861B1 (ko) 2013-02-21 2021-09-10 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 바이러스 감염의 치료를 위한 2-아미노피리미딘 유도체
DK2978429T3 (en) 2013-03-29 2017-05-15 Janssen Sciences Ireland Uc MACROCYCLIC DEAZA PURINONES FOR TREATING VIRUS INFECTIONS
AU2014270418B2 (en) 2013-05-24 2017-11-30 Janssen Sciences Ireland Uc Pyridone derivatives for the treatment of viral infections and further diseases
ES2645950T3 (es) 2013-06-27 2017-12-11 Janssen Sciences Ireland Uc Derivados de pirrolo[3,2-d]pirimidina para el tratamiento de infecciones víricas y otras enfermedades
CA2913691C (fr) 2013-07-30 2022-01-25 Janssen Sciences Ireland Uc Derives de thieno[3,2-d]pyrimidines destines au traitement d'infections virales
WO2018002319A1 (fr) 2016-07-01 2018-01-04 Janssen Sciences Ireland Uc Dihydropyranopyrimidines pour le traitement d'infections virales
ES2912945T3 (es) * 2016-09-29 2022-05-30 Janssen Sciences Ireland Unlimited Co Profármacos de pirimidina para el tratamiento de infecciones virales y otras enfermedades
TW201945003A (zh) 2018-03-01 2019-12-01 愛爾蘭商健生科學愛爾蘭無限公司 2,4-二胺基喹唑啉衍生物及其醫學用途
WO2020162705A1 (fr) 2019-02-08 2020-08-13 성균관대학교산학협력단 Complexe agoniste du récepteur de type toll 7 ou 8-cholestérol, et son utilisation
WO2021177679A1 (fr) 2020-03-02 2021-09-10 성균관대학교산학협력단 Nanoparticules mimétiques d'agent pathogène vivant basées sur un squelette de paroi cellulaire d'agent pathogène, et leur procédé de production
JP2023536954A (ja) 2020-08-04 2023-08-30 プロジェニア インコーポレイテッド 活性化部位が一時的に不活性化したトール様受容体7または8作用薬と機能性薬物の結合体およびその用途
EP4194006A1 (fr) 2020-08-04 2023-06-14 Progeneer Inc. Vaccin à arnm comprenant un adjuvant permettant un contrôle cinétique
JP2023536945A (ja) 2020-08-04 2023-08-30 プロジェニア インコーポレイテッド 動力学的に作用するアジュバントアンサンブル

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2485531A1 (fr) * 1980-06-25 1981-12-31 Fabre Sa Pierre Nouveaux n-oxydes de diaryl-5,6 as triazines 1-2-4, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
ES2232871T3 (es) 1996-07-03 2005-06-01 Sumitomo Pharmaceuticals Company, Limited Nuevos derivados de purina.
ES2205573T3 (es) 1997-11-28 2004-05-01 Sumitomo Pharmaceuticals Company, Limited Nuevo compuestos heterociclicos.
CN101035773B (zh) * 2004-08-10 2012-06-06 詹森药业有限公司 抑制hiv的1,2,4-三嗪-6-酮衍生物
EP1888587A1 (fr) 2005-05-04 2008-02-20 Pfizer Limited Derives de 2-amido-6-amino-8-oxopurine en tant que modulateurs du recepteur du type toll pour le traitement du cancer et d'infections virales, telles que l'hepatite c
JP4850911B2 (ja) * 2005-09-01 2012-01-11 エフ.ホフマン−ラ ロシュ アーゲー P2x3およびp2x2/3モジュレーターとしてのジアミノピリミジン
RU2352565C1 (ru) * 2007-10-08 2009-04-20 Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" 3-амино-6-ароилметил-5-гидрокси-1,2,4-триазины и способ их получения
PE20091236A1 (es) * 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
WO2012067269A1 (fr) * 2010-11-19 2012-05-24 Dainippon Sumitomo Pharma Co., Ltd. Composés aminoalcoxyphényle et leur utilisation dans le traitement de maladies

Also Published As

Publication number Publication date
CA2886630A1 (fr) 2014-04-10
CA2886630C (fr) 2021-01-26
KR20150084791A (ko) 2015-07-22
NZ706354A (en) 2018-08-31
MX2015004160A (es) 2016-02-05
US20150336907A1 (en) 2015-11-26
CN104812747A (zh) 2015-07-29
KR102138393B1 (ko) 2020-08-14
PH12015500724A1 (en) 2015-06-01
UA114644C2 (uk) 2017-07-10
EP2712866A1 (fr) 2014-04-02
EP2903976B1 (fr) 2016-12-07
HK1208223A1 (en) 2016-02-26
CL2015000787A1 (es) 2015-10-02
ZA201502240B (en) 2016-05-25
CN104812747B (zh) 2017-03-08
PH12015500724B1 (en) 2015-06-01
MX348229B (es) 2017-05-31
BR112015007310B1 (pt) 2022-07-19
EA201500383A1 (ru) 2015-07-30
ES2616496T3 (es) 2017-06-13
MY182558A (en) 2021-01-25
EA026236B1 (ru) 2017-03-31
SG11201502522WA (en) 2015-05-28
US9416114B2 (en) 2016-08-16
EP2903976A1 (fr) 2015-08-12
AU2013326579B2 (en) 2017-04-27
WO2014053516A1 (fr) 2014-04-10
JP2015535839A (ja) 2015-12-17
BR112015007310A2 (pt) 2017-08-08
IL237871A (en) 2017-04-30
JP6298998B2 (ja) 2018-03-28
AU2013326579A1 (en) 2015-04-09

Similar Documents

Publication Publication Date Title
IN2015DN03327A (fr)
PH12014501738A1 (en) Piperidino-pyrimidine derivatives for the treatment of viral infections
PH12015500983A1 (en) Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections
PH12015501648A1 (en) 2-aminopyrimidine derivatives for the treatment of viral infections
PH12015502261A1 (en) Macrocyclic deaza-purinones for the treatment of viral infections
PH12015502797A1 (en) THIENO[3,2-d]PYRIMIDINES DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS
PH12015500274B1 (en) Alkylpyrimidine derivatives for the treatment of viral infections and further diseases
MX347596B (es) Derivados de purina para el tratamiento de infecciones viricas.
MX369803B (es) Derivados de acilaminopirimidina para el tratamiento de infecciones viricas y otras enfermedades.
PH12015502564A1 (en) Pyridone derivatives for the treatment of viral infections and further diseases