SG11201502522WA - 1,2,4-triazine derivatives for the treatment of viral infections. - Google Patents
1,2,4-triazine derivatives for the treatment of viral infections.Info
- Publication number
- SG11201502522WA SG11201502522WA SG11201502522WA SG11201502522WA SG11201502522WA SG 11201502522W A SG11201502522W A SG 11201502522WA SG 11201502522W A SG11201502522W A SG 11201502522WA SG 11201502522W A SG11201502522W A SG 11201502522WA SG 11201502522W A SG11201502522W A SG 11201502522WA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- viral infections
- triazine derivatives
- triazine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306196.2A EP2712866A1 (fr) | 2012-10-01 | 2012-10-01 | Dérivés de 1,2,4-triazine pour le traitement d'infections virales |
| PCT/EP2013/070488 WO2014053516A1 (fr) | 2012-10-01 | 2013-10-01 | Dérivés 1,2,4-triazines pour le traitement d'infections virales |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201502522WA true SG11201502522WA (en) | 2015-05-28 |
Family
ID=46982496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201502522WA SG11201502522WA (en) | 2012-10-01 | 2013-10-01 | 1,2,4-triazine derivatives for the treatment of viral infections. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9416114B2 (fr) |
| EP (2) | EP2712866A1 (fr) |
| JP (1) | JP6298998B2 (fr) |
| KR (1) | KR102138393B1 (fr) |
| CN (1) | CN104812747B (fr) |
| AU (1) | AU2013326579B2 (fr) |
| BR (1) | BR112015007310B1 (fr) |
| CA (1) | CA2886630C (fr) |
| CL (1) | CL2015000787A1 (fr) |
| EA (1) | EA026236B1 (fr) |
| ES (1) | ES2616496T3 (fr) |
| HK (1) | HK1208223A1 (fr) |
| IL (1) | IL237871A (fr) |
| IN (1) | IN2015DN03327A (fr) |
| MX (1) | MX348229B (fr) |
| MY (1) | MY182558A (fr) |
| NZ (1) | NZ706354A (fr) |
| PH (1) | PH12015500724B1 (fr) |
| SG (1) | SG11201502522WA (fr) |
| UA (1) | UA114644C2 (fr) |
| WO (1) | WO2014053516A1 (fr) |
| ZA (1) | ZA201502240B (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3330257T1 (sl) | 2011-04-08 | 2020-07-31 | Janssen Sciences Ireland Unlimited Company | Derivati pirimidina za zdravljenje virusnih okužb |
| ES2690082T3 (es) | 2011-11-09 | 2018-11-19 | Janssen Sciences Ireland Uc | Derivados de purina para el tratamiento de infecciones virales |
| MX360718B (es) | 2012-07-13 | 2018-11-13 | Janssen Sciences Ireland Uc | Purinas macrocíclicas para el tratamiento de infecciones víricas. |
| US9499549B2 (en) | 2012-10-10 | 2016-11-22 | Janssen Sciences Ireland Uc | Pyrrolo[3,2-]pyrimidine derivatives for the treatment of viral infections and other diseases |
| JP6297055B2 (ja) | 2012-11-16 | 2018-03-20 | ヤンセン・サイエンシズ・アイルランド・ユーシー | ウイルス感染症の治療のための複素環置換２−アミノ−キナゾリン誘導体 |
| KR102300861B1 (ko) | 2013-02-21 | 2021-09-10 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 바이러스 감염의 치료를 위한 2-아미노피리미딘 유도체 |
| JP6336036B2 (ja) | 2013-03-29 | 2018-06-06 | ヤンセン・サイエンシズ・アイルランド・ユーシー | ウイルス感染治療のための大環状デアザプリノン |
| SG11201509520QA (en) | 2013-05-24 | 2015-12-30 | Janssen Sciences Ireland Uc | Pyridone derivatives for the treatment of viral infections and further diseases |
| WO2014207082A1 (fr) | 2013-06-27 | 2014-12-31 | Janssen R&D Ireland | Dérivés de pyrrolo[3,2-d]pyrimidine pour le traitement des infections virales et autres maladies |
| MY179503A (en) | 2013-07-30 | 2020-11-09 | Janssen Sciences Ireland Uc | Thieno[3,2-d]pyrimidines derivatives for the treatment of viral infections |
| JP7171444B2 (ja) | 2016-07-01 | 2022-11-15 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | ウイルス感染治療用のジヒドロピラノピリミジン |
| CN109790154B (zh) * | 2016-09-29 | 2023-06-23 | 爱尔兰詹森科学公司 | 用于治疗病毒感染和另外的疾病的嘧啶前药 |
| TW202415645A (zh) | 2018-03-01 | 2024-04-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | ２，４－二胺基喹唑啉衍生物及其醫學用途 |
| JP7287708B2 (ja) | 2019-02-08 | 2023-06-06 | プロジェニア インコーポレイテッド | Ｔｏｌｌ－ｌｉｋｅ受容体７または８アゴニストとコレステロールの結合体およびその用途 |
| WO2021177679A1 (fr) | 2020-03-02 | 2021-09-10 | 성균관대학교산학협력단 | Nanoparticules mimétiques d'agent pathogène vivant basées sur un squelette de paroi cellulaire d'agent pathogène, et leur procédé de production |
| EP4194010A1 (fr) | 2020-08-04 | 2023-06-14 | Progeneer Inc. | Conjugué d'un médicament fonctionnel et d'un agoniste de récepteur de type toll 7 ou 8, dont le site actif est temporairement inactivé et utilisation associée |
| JP2023536945A (ja) | 2020-08-04 | 2023-08-30 | プロジェニア インコーポレイテッド | 動力学的に作用するアジュバントアンサンブル |
| EP4194006A1 (fr) | 2020-08-04 | 2023-06-14 | Progeneer Inc. | Vaccin à arnm comprenant un adjuvant permettant un contrôle cinétique |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2485531A1 (fr) * | 1980-06-25 | 1981-12-31 | Fabre Sa Pierre | Nouveaux n-oxydes de diaryl-5,6 as triazines 1-2-4, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| AU698419B2 (en) | 1996-07-03 | 1998-10-29 | Dainippon Sumitomo Pharma Co., Ltd. | A novel purine derivative |
| WO1999028321A1 (fr) | 1997-11-28 | 1999-06-10 | Sumitomo Pharmaceuticals Company, Limited | Nouveaux composes heterocycliques |
| EP1797050B1 (fr) * | 2004-08-10 | 2013-10-23 | Janssen Pharmaceutica NV | Dérivés de 1,2,4-triazin-6-one destinés à inhiber le hiv |
| CN101203519A (zh) | 2005-05-04 | 2008-06-18 | 辉瑞有限公司 | 用于治疗癌症和病毒感染如丙型肝炎的用作Toll样受体调节剂的2－酰氨基－6－氨基－8－氧代嘌呤衍生物 |
| EP1924564B1 (fr) * | 2005-09-01 | 2016-11-09 | F.Hoffmann-La Roche Ag | Diaminopyrimidines en tant que modulateurs de p2x3 et p2x2/3 |
| RU2352565C1 (ru) * | 2007-10-08 | 2009-04-20 | Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" | 3-амино-6-ароилметил-5-гидрокси-1,2,4-триазины и способ их получения |
| PE20091236A1 (es) | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
| WO2012067269A1 (fr) * | 2010-11-19 | 2012-05-24 | Dainippon Sumitomo Pharma Co., Ltd. | Composés aminoalcoxyphényle et leur utilisation dans le traitement de maladies |
-
2012
- 2012-10-01 EP EP12306196.2A patent/EP2712866A1/fr not_active Withdrawn
-
2013
- 2013-10-01 MY MYPI2015000804A patent/MY182558A/en unknown
- 2013-10-01 BR BR112015007310-7A patent/BR112015007310B1/pt active IP Right Grant
- 2013-10-01 SG SG11201502522WA patent/SG11201502522WA/en unknown
- 2013-10-01 US US14/432,269 patent/US9416114B2/en active Active
- 2013-10-01 WO PCT/EP2013/070488 patent/WO2014053516A1/fr active Application Filing
- 2013-10-01 KR KR1020157009515A patent/KR102138393B1/ko active IP Right Grant
- 2013-10-01 NZ NZ706354A patent/NZ706354A/en unknown
- 2013-10-01 ES ES13773690.6T patent/ES2616496T3/es active Active
- 2013-10-01 JP JP2015533635A patent/JP6298998B2/ja active Active
- 2013-10-01 MX MX2015004160A patent/MX348229B/es active IP Right Grant
- 2013-10-01 CA CA2886630A patent/CA2886630C/fr active Active
- 2013-10-01 AU AU2013326579A patent/AU2013326579B2/en active Active
- 2013-10-01 UA UAA201504222A patent/UA114644C2/uk unknown
- 2013-10-01 EP EP13773690.6A patent/EP2903976B1/fr active Active
- 2013-10-01 CN CN201380050972.5A patent/CN104812747B/zh active Active
- 2013-10-01 IN IN3327DEN2015 patent/IN2015DN03327A/en unknown
- 2013-10-01 EA EA201500383A patent/EA026236B1/ru not_active IP Right Cessation
-
2015
- 2015-03-22 IL IL237871A patent/IL237871A/en active IP Right Grant
- 2015-03-30 CL CL2015000787A patent/CL2015000787A1/es unknown
- 2015-03-31 ZA ZA2015/02240A patent/ZA201502240B/en unknown
- 2015-03-31 PH PH12015500724A patent/PH12015500724B1/en unknown
- 2015-09-11 HK HK15108914.9A patent/HK1208223A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2886630A1 (fr) | 2014-04-10 |
| EP2903976A1 (fr) | 2015-08-12 |
| WO2014053516A1 (fr) | 2014-04-10 |
| US9416114B2 (en) | 2016-08-16 |
| MY182558A (en) | 2021-01-25 |
| US20150336907A1 (en) | 2015-11-26 |
| KR102138393B1 (ko) | 2020-08-14 |
| CL2015000787A1 (es) | 2015-10-02 |
| EA201500383A1 (ru) | 2015-07-30 |
| MX348229B (es) | 2017-05-31 |
| PH12015500724A1 (en) | 2015-06-01 |
| CN104812747B (zh) | 2017-03-08 |
| IN2015DN03327A (fr) | 2015-10-09 |
| AU2013326579A1 (en) | 2015-04-09 |
| ZA201502240B (en) | 2016-05-25 |
| EA026236B1 (ru) | 2017-03-31 |
| JP6298998B2 (ja) | 2018-03-28 |
| BR112015007310A2 (pt) | 2017-08-08 |
| ES2616496T3 (es) | 2017-06-13 |
| HK1208223A1 (en) | 2016-02-26 |
| UA114644C2 (uk) | 2017-07-10 |
| KR20150084791A (ko) | 2015-07-22 |
| NZ706354A (en) | 2018-08-31 |
| MX2015004160A (es) | 2016-02-05 |
| IL237871A (en) | 2017-04-30 |
| JP2015535839A (ja) | 2015-12-17 |
| EP2712866A1 (fr) | 2014-04-02 |
| BR112015007310B1 (pt) | 2022-07-19 |
| EP2903976B1 (fr) | 2016-12-07 |
| CA2886630C (fr) | 2021-01-26 |
| PH12015500724B1 (en) | 2015-06-01 |
| AU2013326579B2 (en) | 2017-04-27 |
| CN104812747A (zh) | 2015-07-29 |
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