IN2014MN00714A - - Google Patents

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Publication number
IN2014MN00714A
IN2014MN00714A IN714MUN2014A IN2014MN00714A IN 2014MN00714 A IN2014MN00714 A IN 2014MN00714A IN 714MUN2014 A IN714MUN2014 A IN 714MUN2014A IN 2014MN00714 A IN2014MN00714 A IN 2014MN00714A
Authority
IN
India
Prior art keywords
agonists
present
bitter taste
identifying compounds
provides methods
Prior art date
Application number
Other languages
English (en)
Inventor
Kambiz Shekdar
Purvi Manoj Shah
Joseph Gunnet
Jane V Leland
Peter H Brown
Louise Slade
Original Assignee
Chromocell Corp
Kraft Foods Group Brands Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chromocell Corp, Kraft Foods Group Brands Llc filed Critical Chromocell Corp
Publication of IN2014MN00714A publication Critical patent/IN2014MN00714A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Seasonings (AREA)
IN714MUN2014 2011-10-20 2012-10-22 IN2014MN00714A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161549693P 2011-10-20 2011-10-20
PCT/US2012/061400 WO2013059836A1 (en) 2011-10-20 2012-10-22 Assays for identifying compounds that modulate bitter taste

Publications (1)

Publication Number Publication Date
IN2014MN00714A true IN2014MN00714A (de) 2015-07-03

Family

ID=48141484

Family Applications (1)

Application Number Title Priority Date Filing Date
IN714MUN2014 IN2014MN00714A (de) 2011-10-20 2012-10-22

Country Status (7)

Country Link
US (2) US9347934B2 (de)
EP (1) EP2769216B1 (de)
JP (1) JP6122858B2 (de)
CN (1) CN103998933B (de)
IN (1) IN2014MN00714A (de)
SG (1) SG11201401268RA (de)
WO (1) WO2013059836A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015026901A2 (pt) 2013-04-24 2017-11-14 Chromocell Corp ensaios para identificar compostos que modulam o sabor amargo
EP3329275B1 (de) * 2015-07-28 2022-03-16 Mars, Incorporated Screening-verfahren mit t2r-rezeptoren des hundes und damit identifizierte tierfutterprodukte und -zusammensetzungen
CN112442107B (zh) * 2020-11-18 2023-05-09 渤海大学 一种苦味抑制肽及其应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL118460A (en) * 1996-05-28 1999-09-22 Dead Sea Works Ltd Edible salt mixture
WO2000038536A2 (en) 1998-12-23 2000-07-06 Mount Sinai School Of Medicine Of New York University Inhibitors of the bitter taste response
US6692965B1 (en) 1999-11-23 2004-02-17 Chromocell Corporation Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences
CN1341632A (zh) * 2000-09-05 2002-03-27 上海博德基因开发有限公司 一种新的多肽——人味觉感受器蛋白t2r6-17.05和编码这种多肽的多核苷酸
US7883856B2 (en) 2001-04-05 2011-02-08 Senomyx Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
US8030008B2 (en) * 2001-04-05 2011-10-04 Senomyx, Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
EP2267129B1 (de) 2002-09-25 2015-03-25 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Bittergeschmack-Rezeptoren
EP2806035B1 (de) 2004-02-18 2017-09-13 Chromocell Corporation Verfahren und Materialien, die Signalsonden verwenden
EP1815015B1 (de) 2004-11-18 2012-05-23 Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke Stiftung des Öffentlichen Rechts Agonisten des bittergeschmacksrezeptors sowie deren verwendung
EP1907847A4 (de) 2005-06-22 2009-07-01 Senomyx Inc Identifizierung menschlicher t2r-rezeptoren, die durch bittere moleküle in kaffee (chlorogene lactone) aktiviert werden, und tests in verbindung damit
US7923047B2 (en) * 2006-06-30 2011-04-12 Conagra Foods Rdm, Inc. Seasoning and method for seasoning a food product while reducing dietary sodium intake
US20080167286A1 (en) * 2006-12-12 2008-07-10 Abbott Laboratories Pharmaceutical compositions and their methods of use
EP2137322B1 (de) 2007-03-30 2013-02-27 Givaudan SA Verfahren zur identifizierung von tas2r modulatoren
WO2008119197A1 (en) 2007-03-30 2008-10-09 Givaudan Sa 4-(2, 2, 3-trimethylcyclopentyl) butanoic acid used as an off-note masking agent in consumables
BRPI0809856B1 (pt) 2007-03-30 2016-08-23 Givaudan Sa composto de bloqueio de nota desagradável (off-note) amarga, composição de sabor, produto consumível e método de bloqueio de notas desagradáveis em produtos consumíveis
EP1983342A1 (de) 2007-04-18 2008-10-22 Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand Antagonisten von Bittergeschmacksrezeptoren und Verwendungen davon
EP2185007B1 (de) 2007-07-30 2018-05-23 Givaudan SA Mono- oder bicyclische carbonsäuren als blocker von sensorischen fehltönen
CN104130247B (zh) * 2007-08-21 2018-06-01 塞诺米克斯公司 人t2r苦味受体及其用途
WO2009102569A2 (en) 2008-02-01 2009-08-20 Chromocell Corporation Novel cell lines and methods
US8546085B2 (en) * 2008-06-13 2013-10-01 Givaudan Sa Methods of identifying modulators of the bitter taste receptor TAS2R44
US8603762B2 (en) * 2008-08-07 2013-12-10 Givaudan Sa Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor TAS2R46
NZ603996A (en) * 2009-02-02 2014-03-28 Chromocell Corp Cells or cell lines that stably express a bitter taste receptor and methods of making them
WO2010099983A1 (en) 2009-03-06 2010-09-10 Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Methods for isolating agonists and antagonists of taste receptors
US20130040317A1 (en) 2011-08-08 2013-02-14 The University Of North Carolina At Chapel Hill Cell lines comprising endogenous taste receptors and their uses

Also Published As

Publication number Publication date
US9347934B2 (en) 2016-05-24
EP2769216A4 (de) 2015-05-13
US20160299127A1 (en) 2016-10-13
SG11201401268RA (en) 2014-05-29
JP2014530628A (ja) 2014-11-20
EP2769216B1 (de) 2017-01-04
WO2013059836A1 (en) 2013-04-25
CN103998933A (zh) 2014-08-20
US20140248639A1 (en) 2014-09-04
CN103998933B (zh) 2016-12-14
EP2769216A1 (de) 2014-08-27
JP6122858B2 (ja) 2017-04-26

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