IN2014DN09939A - - Google Patents
Info
- Publication number
- IN2014DN09939A IN2014DN09939A IN9939DEN2014A IN2014DN09939A IN 2014DN09939 A IN2014DN09939 A IN 2014DN09939A IN 9939DEN2014 A IN9939DEN2014 A IN 9939DEN2014A IN 2014DN09939 A IN2014DN09939 A IN 2014DN09939A
- Authority
- IN
- India
- Prior art keywords
- ethyl
- imidazo
- pyridin
- carbonyl
- phenyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Nutrition Science (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Obesity (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66059205P | 2005-03-11 | 2005-03-11 | |
PCT/IB2006/000754 WO2006095268A1 (fr) | 2005-03-11 | 2006-03-01 | Formes cristallines d'un derive d'imidazole |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN09939A true IN2014DN09939A (fr) | 2015-08-14 |
Family
ID=36649530
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN9939DEN2014 IN2014DN09939A (fr) | 2005-03-11 | 2006-03-01 |
Country Status (21)
Country | Link |
---|---|
US (1) | US7960407B2 (fr) |
EP (1) | EP1861400B1 (fr) |
JP (1) | JP5069415B2 (fr) |
KR (1) | KR100911073B1 (fr) |
CN (1) | CN101137656B (fr) |
AR (1) | AR055567A1 (fr) |
AT (1) | ATE469150T1 (fr) |
AU (1) | AU2006221699A1 (fr) |
BR (1) | BRPI0608819B8 (fr) |
CA (1) | CA2600510C (fr) |
DE (1) | DE602006014516D1 (fr) |
ES (1) | ES2344310T3 (fr) |
IL (1) | IL185145A0 (fr) |
IN (1) | IN2014DN09939A (fr) |
MX (1) | MX2007011110A (fr) |
NL (1) | NL300944I2 (fr) |
PL (1) | PL1861400T3 (fr) |
RU (1) | RU2357968C1 (fr) |
TW (1) | TW200643021A (fr) |
WO (1) | WO2006095268A1 (fr) |
ZA (1) | ZA200707568B (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012503605A (ja) | 2008-09-25 | 2012-02-09 | メルク カナダ インコーポレイテッド | Ep4受容体アンタゴニストとしてのベータ−カルボリンスルホニルウレア誘導体 |
BRPI1014174B8 (pt) | 2009-04-22 | 2021-05-25 | Askat Inc | uso de um composto selecionado a partir de 4-((1s)-1-{[5-cloro-2-(4-fluorofenóxi)benzoil]amino}etil)ácido benzóico, 4-[(1s)-1-({[5-cloro-2-(3-fluorofenóxi)piridin-3-il]carbonil}amino)etil]ácido benzóico e 3-[2-(4-{2-etil-4,6-dimetil-1h-imidazo[4,5-c]piridin-1-il}fenil)etil]-1-[(4-metilbenzeno)sulfonil]urea para tratamento de um câncer epitelial relacionado à pge2 |
CN102770159A (zh) | 2010-02-22 | 2012-11-07 | 拉夸里亚创药株式会社 | Ep-4受体拮抗剂在治疗il-23介导疾病中的用途 |
RU2451680C1 (ru) | 2011-02-21 | 2012-05-27 | Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" | Клатратный комплекс циклодекстрина или арабиногалактана с 9-фенил-симм-октагидроселеноксантеном, способ его получения (варианты), фармацевтическая композиция и лекарственное средство |
RU2464042C1 (ru) * | 2011-03-31 | 2012-10-20 | Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" | КЛАТРАТНЫЙ КОМПЛЕКС β-ЦИКЛОДЕКСТРИНА С ПРОИЗВОДНЫМ 5-ГИДРОКСИ-4-АМИНОМЕТИЛ-1-ЦИКЛОГЕКСИЛ(ИЛИ ЦИКЛОГЕПТИЛ)-3-АЛКОКСИКАРБОНИЛИНДОЛА, СПОСОБ ЕГО ПОЛУЧЕНИЯ (ВАРИАНТЫ), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И ЛЕКАРСТВЕННОЕ СРЕДСТВО |
US10391086B2 (en) | 2013-03-19 | 2019-08-27 | Askat Inc. | Use of EP4 receptor antagonists in the treatment of cartilage disease |
CN105163761B (zh) * | 2013-03-19 | 2018-12-21 | 株式会社AskAt | Ep4受体拮抗剂在软骨疾病的治疗中的用途 |
PL3113774T3 (pl) * | 2014-03-06 | 2022-06-13 | Elanco Animal Health Incorporated | Kompozycje grapiprantu i sposoby ich zastosowania |
CA2997697A1 (fr) * | 2014-03-06 | 2015-09-11 | Aratana Therapeutics, Inc. | Formes cristallines de grapiprant |
US10342785B2 (en) | 2016-11-04 | 2019-07-09 | Askat Inc. | Use of EP4 receptor antagonists for the treatment of NASH-associated liver cancer |
JP2021522211A (ja) | 2018-04-16 | 2021-08-30 | アリーズ セラピューティクス, インコーポレイテッド | Ep4阻害剤およびその使用 |
WO2019245590A1 (fr) | 2018-06-18 | 2019-12-26 | Avista Pharma Solutions, Inc. | Composés chimiques |
CN113301896A (zh) * | 2018-07-11 | 2021-08-24 | 阿瑞斯医疗有限公司 | Ep4抑制剂和其合成 |
US20210315909A1 (en) * | 2018-07-11 | 2021-10-14 | Arrys Therapeutics, Inc. | Polymorphic compounds and uses thereof |
CA3128346A1 (fr) | 2019-01-30 | 2020-08-06 | Avista Pharma Solutions, Inc. | Procede de synthese et nouveaux intermediaires |
CA3128024A1 (fr) | 2019-01-30 | 2020-08-06 | Avista Pharma Solutions, Inc. | Composes chimiques |
US11254675B2 (en) | 2019-08-12 | 2022-02-22 | Cadila Healthcare Limited | Process for preparation of grapiprant |
WO2021226162A1 (fr) | 2020-05-05 | 2021-11-11 | Arrys Therapeutics, Inc. | Antagonistes de l'ep4 et leur utilisation dans le traitement des maladies prolifératives" |
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HN2001000224A (es) * | 2000-10-19 | 2002-06-13 | Pfizer | Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos. |
AU2003214525B2 (en) * | 2002-04-12 | 2008-09-25 | Pfizer Inc. | Use of EP4 receptor ligands in the treatment of IL-6 involved diseases |
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Publication number | Publication date |
---|---|
BRPI0608819B8 (pt) | 2021-05-25 |
MX2007011110A (es) | 2008-02-21 |
CN101137656A (zh) | 2008-03-05 |
RU2357968C1 (ru) | 2009-06-10 |
DE602006014516D1 (fr) | 2010-07-08 |
BRPI0608819A2 (pt) | 2010-01-26 |
AU2006221699A1 (en) | 2006-09-14 |
WO2006095268A1 (fr) | 2006-09-14 |
BRPI0608819A8 (pt) | 2017-10-10 |
ZA200707568B (en) | 2009-09-30 |
EP1861400B1 (fr) | 2010-05-26 |
ES2344310T3 (es) | 2010-08-24 |
KR20070103484A (ko) | 2007-10-23 |
RU2007133802A (ru) | 2009-03-20 |
PL1861400T3 (pl) | 2010-09-30 |
IL185145A0 (en) | 2007-12-03 |
CA2600510C (fr) | 2010-11-02 |
CA2600510A1 (fr) | 2006-09-14 |
ATE469150T1 (de) | 2010-06-15 |
NL300944I2 (nl) | 2018-08-07 |
JP2006249089A (ja) | 2006-09-21 |
CN101137656B (zh) | 2010-12-22 |
US7960407B2 (en) | 2011-06-14 |
TW200643021A (en) | 2006-12-16 |
AR055567A1 (es) | 2007-08-22 |
JP5069415B2 (ja) | 2012-11-07 |
US20090018158A1 (en) | 2009-01-15 |
KR100911073B1 (ko) | 2009-08-06 |
EP1861400A1 (fr) | 2007-12-05 |
BRPI0608819B1 (pt) | 2019-11-12 |
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