IN2014DN09939A - - Google Patents

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Publication number
IN2014DN09939A
IN2014DN09939A IN9939DEN2014A IN2014DN09939A IN 2014DN09939 A IN2014DN09939 A IN 2014DN09939A IN 9939DEN2014 A IN9939DEN2014 A IN 9939DEN2014A IN 2014DN09939 A IN2014DN09939 A IN 2014DN09939A
Authority
IN
India
Prior art keywords
ethyl
imidazo
pyridin
carbonyl
phenyl
Prior art date
Application number
Inventor
Haruta Naoaki
Kato Tomoki
Jane Li Zheng
Numata Toyoharu
Vincent Trask Andrew
Original Assignee
Raqualia Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raqualia Pharma Inc filed Critical Raqualia Pharma Inc
Publication of IN2014DN09939A publication Critical patent/IN2014DN09939A/en

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Abstract

A process for the preparation of essentially pure, crystalline, N-[({2-[4-(2-Ethyl-4,6- dimethyHH-imidazo[4,5-c]pyridin-l-yl)phenyl]ethyl}amino)carbonyl]-4- methylbenzenesulfonamide Polymorph Form A, which has a powder X-ray diffraction pattern obtained by irradiation with Cu Ka radiation which includes main peaks at 2- Theta° 9.8,13.2,13.4, 13.7, 14.1, 17.5, 19.0, 21.6, 24.0 and 25.7+/-0.2, characterized by crystallization from a solution of A^-[({2-[4-(2-Ethyl-4,6-dimethyl-li^-imidazo[4,5- c]pyridin-l-yl)phenyl]ethyl}amino)carbonyl]~4-methylbenzenesulfonamide in ethyl acetate or acetone.
IN9939DEN2014 2005-03-11 2006-03-01 IN2014DN09939A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66059205P 2005-03-11 2005-03-11
PCT/IB2006/000754 WO2006095268A1 (en) 2005-03-11 2006-03-01 Crystal forms of an imidazole derivative

Publications (1)

Publication Number Publication Date
IN2014DN09939A true IN2014DN09939A (en) 2015-08-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
IN9939DEN2014 IN2014DN09939A (en) 2005-03-11 2006-03-01

Country Status (21)

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US (1) US7960407B2 (en)
EP (1) EP1861400B1 (en)
JP (1) JP5069415B2 (en)
KR (1) KR100911073B1 (en)
CN (1) CN101137656B (en)
AR (1) AR055567A1 (en)
AT (1) ATE469150T1 (en)
AU (1) AU2006221699A1 (en)
BR (1) BRPI0608819B8 (en)
CA (1) CA2600510C (en)
DE (1) DE602006014516D1 (en)
ES (1) ES2344310T3 (en)
IL (1) IL185145A0 (en)
IN (1) IN2014DN09939A (en)
MX (1) MX2007011110A (en)
NL (1) NL300944I2 (en)
PL (1) PL1861400T3 (en)
RU (1) RU2357968C1 (en)
TW (1) TW200643021A (en)
WO (1) WO2006095268A1 (en)
ZA (1) ZA200707568B (en)

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ES2960438T3 (en) * 2009-04-22 2024-03-04 Askat Inc Selective EP4 receptor antagonist substance for cancer treatment
CA2789665C (en) * 2010-02-22 2020-06-16 Raqualia Pharma Inc. Use of ep4 receptor antagonists in the treatment of il-23 mediated diseases
RU2451680C1 (en) 2011-02-21 2012-05-27 Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" Clatrate complex of cyclodextrine or arabinogalactane with 9-phenyl-symm-octahydroselenoxantene, its production method (versions), pharmaceutical composition and medication
RU2464042C1 (en) * 2011-03-31 2012-10-20 Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" β-CYCLODEXTRINE CLATHRATE COMPLEX WITH 5-HYDROXY-4-AMINOMETHYL-1 -CYCLOHEXYL(OR CYCLOHEPTYL)-3-ALKOXYCARBONYLINDOLE DERIVATIVE, METHOD FOR PREPARING IT (VERSIONS), PHARMACEUTICAL COMPOSITION AND DRUG
US10391086B2 (en) 2013-03-19 2019-08-27 Askat Inc. Use of EP4 receptor antagonists in the treatment of cartilage disease
KR102239641B1 (en) 2013-03-19 2021-04-13 에스크엣 인크. Use of ep4 receptor antagonists in the treatment of cartilage disease
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