IN2014DN06132A - - Google Patents
Info
- Publication number
- IN2014DN06132A IN2014DN06132A IN6132DEN2014A IN2014DN06132A IN 2014DN06132 A IN2014DN06132 A IN 2014DN06132A IN 6132DEN2014 A IN6132DEN2014 A IN 6132DEN2014A IN 2014DN06132 A IN2014DN06132 A IN 2014DN06132A
- Authority
- IN
- India
- Prior art keywords
- formula
- pharmaceutical composition
- administering
- subject
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261586450P | 2012-01-13 | 2012-01-13 | |
US201261622627P | 2012-04-11 | 2012-04-11 | |
PCT/US2013/021245 WO2013106717A1 (en) | 2012-01-13 | 2013-01-11 | Anesthetic compounds and related methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN06132A true IN2014DN06132A (da) | 2015-08-14 |
Family
ID=48781947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN6132DEN2014 IN2014DN06132A (da) | 2012-01-13 | 2013-01-11 |
Country Status (23)
Country | Link |
---|---|
US (4) | US9156825B2 (da) |
EP (2) | EP3184512B1 (da) |
JP (1) | JP6196986B2 (da) |
CN (2) | CN104168899B (da) |
AU (1) | AU2013207811B2 (da) |
BR (1) | BR112014017230A2 (da) |
CA (1) | CA2861071C (da) |
CY (1) | CY1118842T1 (da) |
DK (1) | DK2802325T3 (da) |
EA (1) | EA027976B1 (da) |
ES (1) | ES2617536T3 (da) |
HR (1) | HRP20170330T1 (da) |
HU (1) | HUE030892T2 (da) |
IN (1) | IN2014DN06132A (da) |
LT (1) | LT2802325T (da) |
NZ (1) | NZ627274A (da) |
PL (1) | PL2802325T3 (da) |
PT (1) | PT2802325T (da) |
RS (1) | RS56025B1 (da) |
SG (1) | SG11201403980VA (da) |
SI (1) | SI2802325T1 (da) |
WO (1) | WO2013106717A1 (da) |
ZA (1) | ZA201405248B (da) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6983416B2 (ja) * | 2015-10-10 | 2021-12-17 | ジアンス・エンファルオカン・ファーマスーティカル・リサーチ・アンド・デベロップメント・カンパニー・リミテッドJiangsu Nhwaluokang Pharmceutical Research And Development Co., Ltd. | エトミデート誘導体ならびにその中間体、調製方法および使用 |
CN105663042A (zh) * | 2016-02-03 | 2016-06-15 | 北京蓝丹医药科技有限公司 | 一种稳定的麻醉药物脂肪乳及其制备方法 |
CN107382870A (zh) * | 2016-05-17 | 2017-11-24 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
CN107445898A (zh) * | 2016-05-30 | 2017-12-08 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
CN107522662A (zh) * | 2016-06-16 | 2017-12-29 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
CN107641105A (zh) * | 2016-07-22 | 2018-01-30 | 四川海思科制药有限公司 | N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途 |
CN106432163A (zh) * | 2016-09-29 | 2017-02-22 | 山东东方农药科技实业有限公司 | 一种螺环内酯类化合物、其合成方法以及其用途 |
CN107652239B (zh) * | 2017-02-24 | 2020-08-04 | 四川大学华西医院 | N-取代咪唑羧酸酯类化合物、制备方法及用途 |
CN109776510B (zh) * | 2018-01-30 | 2023-08-18 | 成都麻沸散医药科技有限公司 | 一种n-取代咪唑甲酸酯类衍生物及其用途 |
CN109053410A (zh) * | 2018-08-06 | 2018-12-21 | 兰博尔开封科技有限公司 | 一种合成1-羟基环己基甲酸的新工艺及应用 |
CN112512591A (zh) | 2018-09-26 | 2021-03-16 | 江苏恒瑞医药股份有限公司 | 依喜替康类似物的配体-药物偶联物及其制备方法和应用 |
JP7408646B2 (ja) | 2018-09-30 | 2024-01-05 | ジエンス ハンソー ファーマスーティカル グループ カンパニー リミテッド | 抗-b7h3抗体-エキサテカンアナログコンジュゲート及びその医薬用途 |
CN109761906B (zh) * | 2019-03-02 | 2023-08-11 | 成都麻沸散医药科技有限公司 | 一种取代咪唑甲酸酯类衍生物及其用途 |
CN110003188B (zh) * | 2019-03-27 | 2022-08-26 | 成都麻沸散医药科技有限公司 | 取代吡咯甲酸酯类衍生物及其用途 |
WO2021052402A1 (zh) | 2019-09-18 | 2021-03-25 | 四川百利药业有限责任公司 | 一种喜树碱衍生物及其偶联物 |
WO2021068943A1 (zh) * | 2019-10-11 | 2021-04-15 | 成都麻沸散医药科技有限公司 | 一种取代氮杂环化合物及其麻醉作用 |
CN110669017B (zh) * | 2019-10-11 | 2023-08-04 | 成都麻沸散医药科技有限公司 | 多取代三唑甲酸酯类衍生物及其用途 |
CN112174890B (zh) * | 2020-10-09 | 2022-05-27 | 成都麻沸散医药科技有限公司 | 酮取代杂环化合物及其麻醉作用 |
WO2021115426A1 (zh) | 2019-12-12 | 2021-06-17 | 江苏恒瑞医药股份有限公司 | 抗密蛋白抗体药物偶联物及其医药用途 |
WO2021121204A1 (zh) | 2019-12-16 | 2021-06-24 | 江苏恒瑞医药股份有限公司 | 抗cea抗体-依喜替康类似物偶联物及其医药用途 |
TW202140078A (zh) | 2020-01-22 | 2021-11-01 | 大陸商上海森輝醫藥有限公司 | 艾日布林衍生物的藥物偶聯物、其製備方法及其在醫藥上的應用 |
EP4095148A4 (en) | 2020-01-22 | 2023-07-26 | Jiangsu Hengrui Medicine Co., Ltd. | ANTI-TROP-2 ANTIBODY EXATECAN ANALOGUE CONJUGATE AND MEDICAL USE THEREOF |
MX2022011769A (es) | 2020-03-25 | 2022-10-18 | Jiangsu Hengrui Pharmaceuticals Co Ltd | Metodo de preparacion de medicamento de conjugado de anticuerpo. |
TW202144016A (zh) | 2020-03-25 | 2021-12-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 抗psma抗體-依喜替康類似物偶聯物及其醫藥用途 |
JP2023518583A (ja) | 2020-03-25 | 2023-05-02 | 江蘇恒瑞医薬股▲ふん▼有限公司 | 抗体薬物複合体を含む医薬組成物及びその使用 本願は、2020年3月25日に提出された中国特許出願(出願番号cn 202010219601.7)及び2021年3月17日に提出された中国特許出願(出願番号cn 202110287012.7)の優先権を主張する。 |
AU2022316425A1 (en) | 2021-07-22 | 2024-02-01 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Drug conjugate of eribulin derivative |
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US3354173A (en) | 1964-04-16 | 1967-11-21 | Janssen Pharmaceutica Nv | Imidazole carboxylates |
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CA1066709A (en) | 1975-03-10 | 1979-11-20 | Walter A.M. Helsen | Preparation of loweralkyl imidazole carboxylates |
GR64915B (en) | 1978-09-14 | 1980-06-09 | Janssen Pharmaceutica Nv | Improved etomidate-containing compositions |
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CN102548964B (zh) | 2009-07-10 | 2014-09-24 | 通用医疗公司 | 不抑制肾上腺皮质类固醇合成的依托咪酯类似物 |
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2013
- 2013-01-11 WO PCT/US2013/021245 patent/WO2013106717A1/en active Application Filing
- 2013-01-11 RS RS20170208A patent/RS56025B1/sr unknown
- 2013-01-11 EA EA201491362A patent/EA027976B1/ru not_active IP Right Cessation
- 2013-01-11 SG SG11201403980VA patent/SG11201403980VA/en unknown
- 2013-01-11 HU HUE13735638A patent/HUE030892T2/hu unknown
- 2013-01-11 PT PT137356382T patent/PT2802325T/pt unknown
- 2013-01-11 AU AU2013207811A patent/AU2013207811B2/en active Active
- 2013-01-11 BR BR112014017230-7A patent/BR112014017230A2/pt not_active IP Right Cessation
- 2013-01-11 US US14/371,651 patent/US9156825B2/en active Active
- 2013-01-11 ES ES13735638.2T patent/ES2617536T3/es active Active
- 2013-01-11 SI SI201330552A patent/SI2802325T1/sl unknown
- 2013-01-11 LT LTEP13735638.2T patent/LT2802325T/lt unknown
- 2013-01-11 JP JP2014552332A patent/JP6196986B2/ja active Active
- 2013-01-11 PL PL13735638T patent/PL2802325T3/pl unknown
- 2013-01-11 CA CA2861071A patent/CA2861071C/en active Active
- 2013-01-11 CN CN201380014062.1A patent/CN104168899B/zh active Active
- 2013-01-11 DK DK13735638.2T patent/DK2802325T3/da active
- 2013-01-11 IN IN6132DEN2014 patent/IN2014DN06132A/en unknown
- 2013-01-11 EP EP16198942.1A patent/EP3184512B1/en active Active
- 2013-01-11 NZ NZ627274A patent/NZ627274A/en not_active IP Right Cessation
- 2013-01-11 CN CN201710140475.4A patent/CN107382812A/zh active Pending
- 2013-01-11 EP EP13735638.2A patent/EP2802325B1/en active Active
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2014
- 2014-07-17 ZA ZA2014/05248A patent/ZA201405248B/en unknown
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2015
- 2015-07-24 US US14/808,413 patent/US9522136B2/en active Active
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2016
- 2016-11-10 US US15/348,790 patent/US9820971B2/en active Active
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2017
- 2017-02-24 CY CY20171100255T patent/CY1118842T1/el unknown
- 2017-02-27 HR HRP20170330TT patent/HRP20170330T1/hr unknown
- 2017-10-19 US US15/788,351 patent/US10154991B2/en active Active
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