IN2014CN03062A - - Google Patents

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Publication number
IN2014CN03062A
IN2014CN03062A IN3062CHN2014A IN2014CN03062A IN 2014CN03062 A IN2014CN03062 A IN 2014CN03062A IN 3062CHN2014 A IN3062CHN2014 A IN 3062CHN2014A IN 2014CN03062 A IN2014CN03062 A IN 2014CN03062A
Authority
IN
India
Prior art keywords
methods
same
kinase inhibitors
map kinase
provides therapeutic
Prior art date
Application number
Other languages
English (en)
Inventor
Paul Polakis
Jyoti Asundi
Suzanna Clark
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IN2014CN03062A publication Critical patent/IN2014CN03062A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
IN3062CHN2014 2011-10-28 2012-10-24 IN2014CN03062A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161552893P 2011-10-28 2011-10-28
US201261678978P 2012-08-02 2012-08-02
PCT/US2012/061533 WO2013063001A1 (en) 2011-10-28 2012-10-24 Therapeutic combinations and methods of treating melanoma

Publications (1)

Publication Number Publication Date
IN2014CN03062A true IN2014CN03062A (da) 2015-07-31

Family

ID=48168400

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3062CHN2014 IN2014CN03062A (da) 2011-10-28 2012-10-24

Country Status (18)

Country Link
EP (1) EP2776051A4 (da)
JP (2) JP6251682B2 (da)
KR (1) KR20140097205A (da)
CN (1) CN104039340B (da)
AR (1) AR088509A1 (da)
AU (1) AU2012328980A1 (da)
BR (1) BR112014009953A2 (da)
CA (1) CA2850034A1 (da)
CL (1) CL2014001092A1 (da)
CO (1) CO7151543A2 (da)
EA (1) EA201490879A1 (da)
IL (1) IL232135A0 (da)
IN (1) IN2014CN03062A (da)
MX (1) MX2014004991A (da)
PE (1) PE20142312A1 (da)
SG (1) SG11201401815XA (da)
TW (1) TW201325613A (da)
WO (1) WO2013063001A1 (da)

Families Citing this family (7)

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PE20190262A1 (es) 2011-08-01 2019-02-25 Genentech Inc Metodos para tratar el cancer por el uso de antagonistas de union al eje pd-1 e inhibidores de mek
US9216170B2 (en) 2012-03-19 2015-12-22 Hoffmann-La Roche Inc. Combination therapy for proliferative disorders
CN116617401A (zh) 2014-07-15 2023-08-22 豪夫迈·罗氏有限公司 使用pd-1轴结合拮抗剂和mek抑制剂治疗癌症的组合物
MX2017004580A (es) * 2014-10-10 2017-06-27 Pfizer Combinaciones de auristatina sinergica.
WO2017024032A2 (en) * 2015-08-03 2017-02-09 Enb Therapeutics, Llc Compositions and methods for treating cancers associated with etbr activation
FR3053042B1 (fr) * 2016-06-24 2018-08-10 Commissariat A L'energie Atomique Et Aux Energies Alternatives Anticorps dirige contre le sous-type b des recepteurs aux endothelines et ses utilisations
JP7300394B2 (ja) 2017-01-17 2023-06-29 ヘパリジェニックス ゲーエムベーハー 肝再生の促進又は肝細胞死の低減もしくは予防のためのプロテインキナーゼ阻害

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EP2776051A4 (en) 2015-06-17
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CA2850034A1 (en) 2013-05-02
CN104039340B (zh) 2017-04-05
MX2014004991A (es) 2014-05-22
TW201325613A (zh) 2013-07-01
BR112014009953A2 (pt) 2017-12-05
EA201490879A1 (ru) 2014-08-29
CN104039340A (zh) 2014-09-10
JP6251682B2 (ja) 2017-12-20
IL232135A0 (en) 2014-05-28
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WO2013063001A1 (en) 2013-05-02
AR088509A1 (es) 2014-06-11
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CL2014001092A1 (es) 2014-07-25
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JP2018027948A (ja) 2018-02-22
EP2776051A1 (en) 2014-09-17

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