IN2014CN02346A - - Google Patents
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- Publication number
- IN2014CN02346A IN2014CN02346A IN2346CHN2014A IN2014CN02346A IN 2014CN02346 A IN2014CN02346 A IN 2014CN02346A IN 2346CHN2014 A IN2346CHN2014 A IN 2346CHN2014A IN 2014CN02346 A IN2014CN02346 A IN 2014CN02346A
- Authority
- IN
- India
- Prior art keywords
- carboxamide
- imidazole
- hydroxy
- hydrate
- acidic
- Prior art date
Links
- UEWSIIBPZOBMBL-UHFFFAOYSA-N 5-hydroxyimidazole-4-carboxamide Chemical compound NC(=O)C1=C([O-])[NH2+]C=N1 UEWSIIBPZOBMBL-UHFFFAOYSA-N 0.000 abstract 4
- 150000008043 acidic salts Chemical class 0.000 abstract 2
- GFQBSQXXHYLABK-UHFFFAOYSA-N 2-aminopropanediamide Chemical compound NC(=O)C(N)C(N)=O GFQBSQXXHYLABK-UHFFFAOYSA-N 0.000 abstract 1
- MNFZUYIKKJNLRY-UHFFFAOYSA-N 4-hydroxy-1H-imidazole-5-carboxamide trihydrate Chemical compound O.O.O.NC(=O)c1[nH]cnc1O.NC(=O)c1[nH]cnc1O.NC(=O)c1[nH]cnc1O.NC(=O)c1[nH]cnc1O MNFZUYIKKJNLRY-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011213500 | 2011-09-28 | ||
| JP2011213501 | 2011-09-28 | ||
| PCT/JP2012/075106 WO2013047758A1 (ja) | 2011-09-28 | 2012-09-28 | ５－ヒドロキシ－１ｈ－イミダゾール－４－カルボキサミド水和物の結晶及び５－ヒドロキシ－１ｈ－イミダゾール－４－カルボキサミド・３／４水和物の結晶及びその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02346A true IN2014CN02346A (xx) | 2015-06-19 |
Family
ID=47995783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2346CHN2014 IN2014CN02346A (xx) | 2011-09-28 | 2012-09-28 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9108928B2 (xx) |
| EP (1) | EP2762469B1 (xx) |
| KR (1) | KR101970509B1 (xx) |
| CN (1) | CN103827093B (xx) |
| AU (1) | AU2012317424B2 (xx) |
| BR (1) | BR112014007436A2 (xx) |
| CA (1) | CA2850196A1 (xx) |
| HK (1) | HK1197406A1 (xx) |
| IL (2) | IL231677A (xx) |
| IN (1) | IN2014CN02346A (xx) |
| MX (1) | MX354498B (xx) |
| RU (2) | RU2630682C2 (xx) |
| SG (1) | SG11201400974VA (xx) |
| WO (1) | WO2013047758A1 (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2630682C2 (ru) | 2011-09-28 | 2017-09-12 | Фуджифилм Корпорэйшн | Кристалл 5-гидрокси-1н-имидазол-4-карбоксамид•3/4 гидрата, способ его получения и кристалл 5-гидрокси-1н-имидазол-4-карбоксамида гидрата |
| CN104903299B (zh) | 2013-01-15 | 2018-10-16 | 富士胶片株式会社 | 5-羟基-1h-咪唑-4-甲酰胺的硫酸盐 |
| CN105899951B (zh) * | 2014-01-10 | 2019-07-12 | 富士胶片株式会社 | 5-羟基-1h-咪唑-4-甲酰胺的有效给予量的预测装置、黄苷一磷酸的量的测定方法 |
| JP6823660B2 (ja) * | 2016-09-13 | 2021-02-03 | 富士フイルム株式会社 | Ｍｌｌ関連白血病の予防または治療のための医薬、方法、使用及び化合物 |
| EP3686189B1 (en) | 2017-10-27 | 2021-09-01 | FUJIFILM Corporation | Production method for 5-hydroxy-1h-imidazole-4-carboxamide-3/4hydrate |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4181731A (en) * | 1976-09-07 | 1980-01-01 | Sumitomo Chemical Company, Limited | Novel therapeutic application of 4-carbamoyl-5-hydroxyimidazole |
| JPS5625165A (en) * | 1979-08-08 | 1981-03-10 | Sumitomo Chem Co Ltd | Novel imidazole derivative |
| JPS5824569A (ja) | 1981-08-05 | 1983-02-14 | Sumitomo Chem Co Ltd | イミダゾ−ル誘導体の精製方法 |
| US4503235A (en) * | 1983-03-11 | 1985-03-05 | Warner-Lambert Company | Process for producing 4-carbamoyl-1H-imidazolium-5-olate |
| JPS60185727A (ja) * | 1984-03-05 | 1985-09-21 | Sumitomo Chem Co Ltd | ４−カルバモイルイミダゾリウム−５−オレ−ト製剤の安定化法 |
| CA2152863A1 (en) | 1994-07-26 | 1996-01-27 | Yeun-Kwei Han | Preparation of acyclovir |
| US5567816A (en) | 1994-07-26 | 1996-10-22 | Syntex (U.S.A.) Inc. | Preparation of acyclovir using 1,3 dioxolane |
| DE50114223D1 (de) | 2000-09-29 | 2008-09-25 | Basf Se | Verfahren zur herstellung von 1-substituierten 5-chlor-4methylpyrazolen |
| JP2002265601A (ja) | 2001-03-07 | 2002-09-18 | Rikogaku Shinkokai | イミド樹脂 |
| JP2008530179A (ja) * | 2005-02-16 | 2008-08-07 | ソルベイ・フアーマシユーチカルズ・ベー・ブイ | カンナビノイドｃｂ２受容体モジュレーターとしての１ｈ−イミダゾール誘導体 |
| UA94737C2 (ru) * | 2006-02-24 | 2011-06-10 | Лексикон Фармасьютикалз, Инк. | Соединения на основе имидазола, композиция, которая их содержит, и их применение |
| JP5266010B2 (ja) * | 2007-09-14 | 2013-08-21 | 富士フイルム株式会社 | ４−カルバモイル−５−ヒドロキシ−イミダゾール誘導体のスルホン酸塩化合物 |
| KR100982720B1 (ko) * | 2008-02-04 | 2010-09-17 | 주식회사 파마코스텍 | 4-카르바모일-1-β-Ｄ-리보푸라노실이미다졸륨-5-올레이트의 생산을 위한 중간체로서의 2-아미노말론아미드의제조방법 |
| RU2630682C2 (ru) | 2011-09-28 | 2017-09-12 | Фуджифилм Корпорэйшн | Кристалл 5-гидрокси-1н-имидазол-4-карбоксамид•3/4 гидрата, способ его получения и кристалл 5-гидрокси-1н-имидазол-4-карбоксамида гидрата |
| TWI573791B (zh) | 2011-09-28 | 2017-03-11 | 富士軟片股份有限公司 | ５－羥基－１ｈ－咪唑－４－甲醯胺．３／４水合物及其結晶之製造方法 |
-
2012
- 2012-09-28 RU RU2014111810A patent/RU2630682C2/ru not_active IP Right Cessation
- 2012-09-28 BR BR112014007436A patent/BR112014007436A2/pt not_active Application Discontinuation
- 2012-09-28 IN IN2346CHN2014 patent/IN2014CN02346A/en unknown
- 2012-09-28 KR KR1020147008200A patent/KR101970509B1/ko active IP Right Grant
- 2012-09-28 CA CA2850196A patent/CA2850196A1/en active Pending
- 2012-09-28 AU AU2012317424A patent/AU2012317424B2/en not_active Ceased
- 2012-09-28 EP EP12835728.2A patent/EP2762469B1/en active Active
- 2012-09-28 MX MX2014003638A patent/MX354498B/es active IP Right Grant
- 2012-09-28 RU RU2017125796A patent/RU2672560C1/ru not_active IP Right Cessation
- 2012-09-28 SG SG11201400974VA patent/SG11201400974VA/en unknown
- 2012-09-28 WO PCT/JP2012/075106 patent/WO2013047758A1/ja active Application Filing
- 2012-09-28 CN CN201280047308.0A patent/CN103827093B/zh not_active Expired - Fee Related
-
2014
- 2014-03-24 IL IL231677A patent/IL231677A/en active IP Right Grant
- 2014-03-26 US US14/226,364 patent/US9108928B2/en active Active
- 2014-10-30 HK HK14110905.7A patent/HK1197406A1/zh not_active IP Right Cessation
-
2015
- 2015-07-10 US US14/796,602 patent/US9567303B2/en active Active
-
2016
- 2016-07-13 IL IL246754A patent/IL246754A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US9567303B2 (en) | 2017-02-14 |
| WO2013047758A1 (ja) | 2013-04-04 |
| MX354498B (es) | 2018-03-08 |
| CN103827093A (zh) | 2014-05-28 |
| RU2630682C2 (ru) | 2017-09-12 |
| US20140275568A1 (en) | 2014-09-18 |
| US9108928B2 (en) | 2015-08-18 |
| NZ622928A (en) | 2015-04-24 |
| IL231677A0 (en) | 2014-05-28 |
| KR101970509B1 (ko) | 2019-04-19 |
| US20150315156A1 (en) | 2015-11-05 |
| AU2012317424A8 (en) | 2014-07-03 |
| KR20140069052A (ko) | 2014-06-09 |
| AU2012317424B2 (en) | 2017-05-18 |
| EP2762469B1 (en) | 2016-11-23 |
| CA2850196A1 (en) | 2013-04-04 |
| EP2762469A1 (en) | 2014-08-06 |
| IL246754A (en) | 2017-08-31 |
| RU2672560C1 (ru) | 2018-11-16 |
| RU2014111810A (ru) | 2015-11-10 |
| BR112014007436A2 (pt) | 2017-04-04 |
| SG11201400974VA (en) | 2014-09-26 |
| IL231677A (en) | 2017-01-31 |
| HK1197406A1 (zh) | 2015-01-16 |
| CN103827093B (zh) | 2016-06-15 |
| MX2014003638A (es) | 2014-05-21 |
| EP2762469A4 (en) | 2015-01-14 |
| AU2012317424A1 (en) | 2014-04-17 |
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