IN2012DN03330A - - Google Patents

Download PDF

Info

Publication number
IN2012DN03330A
IN2012DN03330A IN3330DEN2012A IN2012DN03330A IN 2012DN03330 A IN2012DN03330 A IN 2012DN03330A IN 3330DEN2012 A IN3330DEN2012 A IN 3330DEN2012A IN 2012DN03330 A IN2012DN03330 A IN 2012DN03330A
Authority
IN
India
Prior art keywords
proteins
virus
efficient manner
endoplasmic reticulum
highly efficient
Prior art date
Application number
Other languages
English (en)
Inventor
In Hwan Hwang
Eun Ju Sohn
Eun Hye Kwon
Yun Jeong Na
Eun Hyun Jeon
Se Jin Im
Ki Seok Park
Young Chul Sung
Original Assignee
Helix Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helix Co Ltd filed Critical Helix Co Ltd
Publication of IN2012DN03330A publication Critical patent/IN2012DN03330A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN3330DEN2012 2009-10-06 2010-10-06 IN2012DN03330A (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20090094627 2009-10-06
KR1020100096488A KR101262300B1 (ko) 2009-10-06 2010-10-04 형질전환 식물 유래의 고병원성 조류독감 바이러스 단백질 백신 및 그 제조방법
PCT/KR2010/006821 WO2011043584A2 (ko) 2009-10-06 2010-10-06 형질전환 식물 유래의 고병원성 조류독감 바이러스 단백질 백신 및 그 제조방법

Publications (1)

Publication Number Publication Date
IN2012DN03330A true IN2012DN03330A (de) 2015-10-23

Family

ID=44045255

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3330DEN2012 IN2012DN03330A (de) 2009-10-06 2010-10-06

Country Status (6)

Country Link
US (1) US20120219580A1 (de)
EP (1) EP2486791A4 (de)
KR (1) KR101262300B1 (de)
CN (1) CN102770016A (de)
IN (1) IN2012DN03330A (de)
WO (1) WO2011043584A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101535704B1 (ko) * 2012-12-28 2015-07-27 한국생명공학연구원 항원성 단백질 고정화를 통한 돈단독 백신 제조방법
EP2970397A2 (de) 2013-03-14 2016-01-20 University Of Washington Through Its Center For Commercialization Polypeptide zur behandlung und/oder begrenzung einer influenza-infektion
KR101602562B1 (ko) * 2014-06-10 2016-03-10 포항공과대학교 산학협력단 인플루엔자 a 바이러스 h5n1의 헤마글루티닌을 발현하는 식물체 및 사포닌을 포함하는 경구용 인플루엔자 a 바이러스 h5n1 백신 조성물
US10344293B2 (en) * 2016-05-12 2019-07-09 Bio Applications Inc. Vaccine composition for classical swine fever from plant and manufacturing method thereof
KR102731582B1 (ko) 2016-06-03 2024-11-15 사노피 파스퇴르 인코포레이티드 조작된 인플루엔자 헤마글루티닌 폴리펩티드의 변형
CN107058377A (zh) * 2017-06-16 2017-08-18 深圳惠升生物科技有限公司 植物作为宿主在表达中东呼吸综合征的疫苗中的应用
KR102128453B1 (ko) * 2018-03-23 2020-07-01 주식회사 젠바디 황열 바이러스 유래 ns1 단백질, 이에 특이적으로 결합하는 단일클론항체 및 이의 용도
KR102138272B1 (ko) * 2018-09-19 2020-07-28 주식회사 바이오앱 BiP 단편을 포함하는 재조합 벡터 및 상기 벡터를 이용한 재조합 단백질의 제조 방법
GB2578163A (en) * 2018-10-19 2020-04-22 Univ Pretoria Plant produced avian influenza antigens and their uses in diagnostic assays and devices
KR102317403B1 (ko) * 2019-01-28 2021-10-29 주식회사 바이오앱 당화된 Ag85A 단백질을 포함하는 결핵 예방용 백신 조성물 및 이의 제조방법
KR102209198B1 (ko) * 2019-04-02 2021-02-02 주식회사 바이오앱 식물에서의 발현이 최적화된 재조합 이리신 유전자 및 이를 이용한 재조합 이리신 단백질의 생산 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040242518A1 (en) * 2002-09-28 2004-12-02 Massachusetts Institute Of Technology Influenza therapeutic
KR100769584B1 (ko) 2004-07-30 2007-10-23 학교법인 포항공과대학교 셀룰로오스의 자가가수분해를 위한 셀룰라아제 발현형질전환 식물체 및 이를 이용한 수용성 당의 생산방법
CU23576A1 (es) * 2006-02-28 2010-09-30 Ct Ingenieria Genetica Biotech Antígenos vacunales quiméricos contra el virus de la influenza aviar
DK2023952T3 (en) * 2006-05-18 2015-10-19 Epimmune Inc Induction of immune responses to influenza virus using polypeptide and nucleic acid compositions
CN1884517B (zh) * 2006-06-08 2010-06-30 武汉禾元生物科技有限公司 利用谷物非储藏蛋白为融合载体在胚乳表达多肽的方法及应用
DE602007005017D1 (de) 2006-10-20 2010-04-08 3M Innovative Properties Co Verfahren für leicht zu reinigende substrate und artikel daraus
CN101284130B (zh) * 2007-04-09 2011-12-14 生宝生物科技股份有限公司 利用逆向基因工程技术开发蛋白质疫苗与禽流感疫苗的方法
KR101161622B1 (ko) * 2009-08-31 2012-07-04 헬릭스 주식회사 번역 효율 증진용 dna 단편 및 이를 포함하는 재조합 벡터

Also Published As

Publication number Publication date
EP2486791A4 (de) 2013-06-12
CN102770016A (zh) 2012-11-07
WO2011043584A3 (ko) 2011-10-20
WO2011043584A2 (ko) 2011-04-14
EP2486791A2 (de) 2012-08-15
KR101262300B1 (ko) 2013-05-20
KR20110037880A (ko) 2011-04-13
US20120219580A1 (en) 2012-08-30
WO2011043584A9 (ko) 2011-09-01

Similar Documents

Publication Publication Date Title
IN2012DN03330A (de)
NZ590351A (en) HA1 domain totally or partially free of N-linked glycosylation operatively linked to a regulatory region
PH12015502217B1 (en) Influenza virus-like particle production in plants
AR088858A1 (es) Plantas que tienen mejores rasgos relacionados con el rendimiento y un metodo para producirlas
EA201001198A1 (ru) Рекомбинантные вирусоподобные частицы (вч), схожие с вирусом гриппа, производящиеся в трансгенных растениях, экспрессирующих гемагглютинин
MY182643A (en) Chimeric influenza virus-like particles comprising hemagglutinin
MA32439B1 (fr) Particules pseudovirales (vlp) de la grippe recombinées produites dans des plantes transgéniques exprimant l'hémagglutinine
WO2010036970A3 (en) Influenza vaccines, antigens, compositions, and methods
IN2014CN02114A (de)
NZ627796A (en) Influenza virus vaccines and uses thereof
HUE058165T2 (hu) Növényi eredetû fehérjék elõállításának eljárása
MX2011007961A (es) Determinacion de sexo y metodos de especificacion del mismo.
CL2017001665A1 (es) Inductor haploide
NZ622731A (en) Increasing virus-like particle yield in plants
WO2013043067A3 (en) Dna vaccine, method of inducing the immune response, method of immunisation, antibodies specifically recognising the h5 haemagglutinin of an influenza virus and use of the dna vaccine
MX368142B (es) Metodo de clonacion, expresion y purificacion novedoso para la preparacion de ranibizumab.
CL2015002175A1 (es) Vacuna contra el paramixovirus aviar recombinante y su método de preparación y uso
NZ596366A (en) Enhanced immune response in avian species
EA201300525A1 (ru) Новые вакцины против пандемичного вируса гриппа a/h1n1
AR077181A1 (es) Metodo para proveer plantas recalcitrantes transgenicas maduras por induccion de bbm durante regeneracion
PH12014500369A1 (en) Influenza h5 vaccines
PH12014500550A1 (en) Plants having enhanced yield-related traits and a method for making the same
MX2013012986A (es) Plantas que tienen uno o mas rasgos mejorados relacionados con el rendimento y un metodo para producirlas.
ZA201106852B (en) A method to prepare inactivated vaccine for h9n2 sub-type avian influenza and product
WO2012061239A3 (en) Novel vaccines against pandemic influenza virus a/h1n1