IN2012DN02656A - - Google Patents

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Publication number
IN2012DN02656A
IN2012DN02656A IN2656DEN2012A IN2012DN02656A IN 2012DN02656 A IN2012DN02656 A IN 2012DN02656A IN 2656DEN2012 A IN2656DEN2012 A IN 2656DEN2012A IN 2012DN02656 A IN2012DN02656 A IN 2012DN02656A
Authority
IN
India
Prior art keywords
implant devices
another aspect
bioactive agent
devices
implant
Prior art date
Application number
Other languages
English (en)
Inventor
Bruce W Hudson
Peter Markland
Original Assignee
Evonik Degussa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Corp filed Critical Evonik Degussa Corp
Publication of IN2012DN02656A publication Critical patent/IN2012DN02656A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IN2656DEN2012 2009-09-17 2010-09-16 IN2012DN02656A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24330309P 2009-09-17 2009-09-17
PCT/US2010/049104 WO2011035013A2 (en) 2009-09-17 2010-09-16 Implant devices that differ by release profile and methods of making and using same

Publications (1)

Publication Number Publication Date
IN2012DN02656A true IN2012DN02656A (enExample) 2015-09-11

Family

ID=43218276

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2656DEN2012 IN2012DN02656A (enExample) 2009-09-17 2010-09-16

Country Status (10)

Country Link
US (1) US9399018B2 (enExample)
EP (1) EP2477612A2 (enExample)
JP (1) JP2013505251A (enExample)
KR (1) KR20120102598A (enExample)
CN (1) CN102917693B (enExample)
BR (1) BR112012006103B8 (enExample)
CA (1) CA2774495C (enExample)
IN (1) IN2012DN02656A (enExample)
RU (1) RU2012115120A (enExample)
WO (1) WO2011035013A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005325213B2 (en) 2004-08-04 2010-10-07 Evonik Operations Gmbh Methods for manufacturing delivery devices and devices thereof
JP5675820B2 (ja) * 2009-09-22 2015-02-25 エボニック コーポレイションEvonik Corporation 様々な生物活性剤担持構成を有するインプラントデバイス
US9980850B2 (en) 2016-09-29 2018-05-29 Gesea Biosciences, Inc. Bioerodible contraceptive implant and methods of use thereof
KR102183669B1 (ko) * 2019-03-26 2020-11-26 가톨릭대학교 산학협력단 이중 약물 방출을 위한 약물 전달체
JP6905035B2 (ja) 2019-11-29 2021-07-21 Nissha株式会社 可食性フィルムの製造方法、フィルム製剤及び可食性フィルム

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309669B1 (en) * 1984-03-16 2001-10-30 The United States Of America As Represented By The Secretary Of The Army Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
US4720384A (en) * 1985-05-03 1988-01-19 E. I. Du Pont De Nemours And Company Manufacture of hollow fine tubular drug delivery systems
US4976949A (en) * 1985-10-25 1990-12-11 The University Of Michigan Controlled release dosage form
US4794001A (en) * 1986-03-04 1988-12-27 American Home Products Corporation Formulations providing three distinct releases
JPS63203610A (ja) * 1987-02-12 1988-08-23 ヘキスト・アクチエンゲゼルシヤフト 複数成分からなるインプラント用の持効性医薬製剤
DE3710175A1 (de) * 1987-02-12 1988-08-25 Hoechst Ag Mehrteilige implantierbare arzneizubereitung mit langzeitwirkung
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
JP2702729B2 (ja) * 1988-02-24 1998-01-26 エーザイ株式会社 徐放性埋込剤
US5702716A (en) * 1988-10-03 1997-12-30 Atrix Laboratories, Inc. Polymeric compositions useful as controlled release implants
US5178874A (en) * 1989-06-30 1993-01-12 Smithkline Beechman Corporation Intermittent release dosage form
US5153002A (en) * 1991-03-04 1992-10-06 University Of Montreal Biocompatible gradient controlled release implant
JP3118009B2 (ja) 1991-04-16 2000-12-18 住友製薬株式会社 多層構造を有するコラーゲンおよび/またはゼラチン製剤の製造方法
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
US5429822A (en) * 1992-03-13 1995-07-04 Cambridge Scientific, Inc. Biodegradable bursting release system
GB9223144D0 (en) * 1992-11-05 1992-12-16 Scherer Corp R P Controlled release device
US5456917A (en) * 1993-04-12 1995-10-10 Cambridge Scientific, Inc. Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
US6447796B1 (en) * 1994-05-16 2002-09-10 The United States Of America As Represented By The Secretary Of The Army Sustained release hydrophobic bioactive PLGA microspheres
US6855331B2 (en) * 1994-05-16 2005-02-15 The United States Of America As Represented By The Secretary Of The Army Sustained release hydrophobic bioactive PLGA microspheres
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
US6902743B1 (en) * 1995-05-22 2005-06-07 The United States Of America As Represented By The Secretary Of The Army Therapeutic treatment and prevention of infections with a bioactive material(s) encapuslated within a biodegradable-bio-compatable polymeric matrix
US5705191A (en) * 1995-08-18 1998-01-06 The United States Of America As Represented By The Secretary Of The Navy Sustained delivery of active compounds from tubules, with rational control
JP2002511075A (ja) * 1997-06-04 2002-04-09 デビオ ルシェルシュ ファルマスティク ソシエテ アノニム 薬学的活性成分の制御放出のためのインプラント及びその製造方法
JP2001515854A (ja) * 1997-09-11 2001-09-25 ニュコメデ ダンマルク アクティーゼルスカブ 非ステロイド性抗炎症薬物質(NSAIDs)の改良された開放性多重−単位組成物
US6296831B1 (en) * 1998-04-10 2001-10-02 Battelle Memorial Institute Stimulus sensitive gel with radioisotope and methods of making
WO2000003660A1 (en) * 1998-07-17 2000-01-27 Skyepharma, Inc. Biodegradable compositions for the controlled release of encapsulated substances
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
WO2001007079A1 (en) * 1999-07-26 2001-02-01 Bomac Laboratories Limited Improvements in dispensing vaccines
US20020131988A1 (en) * 1999-12-16 2002-09-19 Foster Todd P. Pharmaceutical implant containing immediate-release and sustained-release components and method of administration
IL150657A0 (en) * 2000-01-20 2003-02-12 Delsys Pharmaceutical Corp Multi-step drug dosage forms
US6479065B2 (en) * 2000-08-10 2002-11-12 Alkermes Controlled Therapeutics, Inc. Process for the preparation of polymer-based sustained release compositions
US20030055075A1 (en) 2001-07-13 2003-03-20 Rubsamen Reid M. Programmable controlled release injectable opioid formulation
NZ519363A (en) * 2002-06-05 2004-02-27 Agres Ltd A novel drug dosing regimen
US7101566B2 (en) 2002-06-28 2006-09-05 Ethicon, Inc. Polymer coated microparticles for sustained release
US7220433B2 (en) * 2003-06-27 2007-05-22 Ethicon, Inc. Compositions for parenteral administration and sustained-release of therapeutic agents
US8329203B2 (en) * 2004-01-12 2012-12-11 The Trustees Of The University Of Pennsylvania Drug-containing implants and methods of use thereof
US8685435B2 (en) * 2004-04-30 2014-04-01 Allergan, Inc. Extended release biodegradable ocular implants
WO2005107715A1 (en) * 2004-05-11 2005-11-17 Debio Recherche Pharmaceutique S.A. Implantable composition
AU2005325213B2 (en) * 2004-08-04 2010-10-07 Evonik Operations Gmbh Methods for manufacturing delivery devices and devices thereof
CN101163464A (zh) * 2004-12-23 2008-04-16 杜雷科特公司 优选含有PEG和PLG混合物的控制释放GnRH的聚合物植入物
US8969415B2 (en) * 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems

Also Published As

Publication number Publication date
BR112012006103A2 (pt) 2016-06-07
US9399018B2 (en) 2016-07-26
BR112012006103B8 (pt) 2021-05-25
WO2011035013A3 (en) 2011-12-29
RU2012115120A (ru) 2013-10-27
US20110142906A1 (en) 2011-06-16
BR112012006103A8 (pt) 2017-10-03
KR20120102598A (ko) 2012-09-18
EP2477612A2 (en) 2012-07-25
CA2774495C (en) 2017-09-26
CN102917693B (zh) 2015-05-20
WO2011035013A2 (en) 2011-03-24
BR112012006103B1 (pt) 2020-10-27
CA2774495A1 (en) 2011-03-24
CN102917693A (zh) 2013-02-06
JP2013505251A (ja) 2013-02-14

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