IN2012DN01850A - - Google Patents
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- Publication number
- IN2012DN01850A IN2012DN01850A IN1850DEN2012A IN2012DN01850A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A IN 1850DEN2012 A IN1850DEN2012 A IN 1850DEN2012A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A
- Authority
- IN
- India
- Prior art keywords
- separation
- line
- units
- fluid
- separation unit
- Prior art date
Links
- 238000000926 separation method Methods 0.000 abstract 11
- 239000012530 fluid Substances 0.000 abstract 4
- 230000007613 environmental effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/24—Automatic injection systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/566,701 US9527010B2 (en) | 2009-09-25 | 2009-09-25 | Separation system and method |
| PCT/SE2010/051003 WO2011037522A1 (en) | 2009-09-25 | 2010-09-20 | Separation system and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN01850A true IN2012DN01850A (https=) | 2015-08-21 |
Family
ID=43779133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1850DEN2012 IN2012DN01850A (https=) | 2009-09-25 | 2010-09-20 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9527010B2 (https=) |
| EP (1) | EP2480305B1 (https=) |
| JP (1) | JP5749270B2 (https=) |
| CN (1) | CN102574026B (https=) |
| AU (1) | AU2010298768B2 (https=) |
| IN (1) | IN2012DN01850A (https=) |
| WO (1) | WO2011037522A1 (https=) |
Families Citing this family (49)
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|---|---|---|---|---|
| WO2011037530A1 (en) * | 2009-09-25 | 2011-03-31 | Ge Healthcare Bio-Sciences Ab | Method and system for preparation of liquid mixtures |
| JP2013519652A (ja) * | 2010-02-12 | 2013-05-30 | ディーエスエム アイピー アセッツ ビー.ブイ. | 単一ユニット抗体精製 |
| CA2808116C (en) * | 2010-07-30 | 2016-06-07 | Pfizer Inc. | Tandem purification of proteins |
| JP2012068244A (ja) * | 2010-09-20 | 2012-04-05 | Asahi Kasei Bioprocess Inc | タンパク質の分離及び精製のための液体クロマトグラフィーのシステム及び方法 |
| CA2814781A1 (en) * | 2010-11-01 | 2012-05-10 | Diderik Reinder Kremer | Single unit ion exchange chromatography antibody purification |
| US20140187749A1 (en) * | 2011-06-16 | 2014-07-03 | Dsm Ip Assets B.V. | Single unit chromatography antibody purification |
| US9096648B2 (en) | 2011-08-19 | 2015-08-04 | Emd Millipore Corporation | Methods of reducing level of one or more impurities in a sample during protein purification |
| EP2578286A1 (en) * | 2011-10-04 | 2013-04-10 | Merck Patent GmbH | Method and apparatus for chromatographic purification |
| ES2985370T3 (es) * | 2011-11-10 | 2024-11-05 | Hoffmann La Roche | Sistema de cromatografía en columna preparativa |
| WO2013075740A1 (en) | 2011-11-23 | 2013-05-30 | Sanofi | Antibody purification method |
| CN104411820B (zh) * | 2012-06-29 | 2017-05-03 | Emd密理博公司 | 在蛋白纯化过程中灭活病毒的方法 |
| NO2994485T3 (https=) * | 2013-05-06 | 2018-06-09 | ||
| CN103439433B (zh) * | 2013-09-11 | 2015-06-10 | 青岛普仁仪器有限公司 | 免稀释作线性曲线的色谱仪及线性曲线测量方法 |
| JPWO2015041218A1 (ja) * | 2013-09-17 | 2017-03-02 | 株式会社カネカ | 新規抗体精製方法及びそれから得られる抗体(NovelAntibodyPurificationMethodandAntibodyobtainedtherefrom)、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体(NovelAntibodyPurificationmethodusingCationExchangerandAntibodyobtainedtherefrom) |
| WO2015117883A1 (en) * | 2014-02-07 | 2015-08-13 | Cmc Biologics A/S | A bioreactor arrangement and continuous process for producing and capturing a biopolymer |
| JP6612242B2 (ja) | 2014-02-14 | 2019-11-27 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 自動化された多段階精製システム及び多段階クロマトグラフィー精製方法 |
| JP6331485B2 (ja) * | 2014-03-04 | 2018-05-30 | 株式会社島津製作所 | 液体クロマトグラフ及び液体クロマトグラフ分析方法 |
| US20170058308A1 (en) * | 2014-05-02 | 2017-03-02 | Novo Nordisk A/S | Integrated continuous biomanufacturing process |
| US11835501B2 (en) | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
| JP6579515B2 (ja) * | 2015-08-10 | 2019-09-25 | 国立大学法人 岡山大学 | アポe含有hdlの測定方法及び測定装置 |
| JP6953508B2 (ja) * | 2016-04-04 | 2021-10-27 | ベーリンガー インゲルハイム エルツェーファウ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 製剤精製のリアルタイムモニタリング |
| GB201622343D0 (en) * | 2016-12-29 | 2017-02-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| US11016110B2 (en) | 2017-01-26 | 2021-05-25 | Myriad Women's Health, Inc. | Reagent delivery and waste management system |
| US11185830B2 (en) | 2017-09-06 | 2021-11-30 | Waters Technologies Corporation | Fluid mixer |
| FR3073424B1 (fr) | 2017-11-16 | 2022-03-25 | Novasep Process | Procede regule de separation d’un melange |
| GB201802593D0 (en) * | 2018-02-16 | 2018-04-04 | Fujifilm Diosynth Biotechnologies Uk Ltd | Rig |
| EP3546475A1 (en) | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
| US20210024873A1 (en) * | 2018-03-27 | 2021-01-28 | Bristol-Myers Squibb Company | Real-time monitoring of protein concentration using ultraviolet signal |
| CN109453545A (zh) * | 2018-12-20 | 2019-03-12 | 上海兆维科技发展有限公司 | 层析柱洗脱液的配液装置 |
| EP3693732A1 (en) * | 2019-02-11 | 2020-08-12 | Bayer Aktiengesellschaft | Influencing a sequential chromatography in real-time |
| CN113382793A (zh) * | 2019-02-11 | 2021-09-10 | 拜耳公司 | 实时影响顺序层析 |
| EP3763429A1 (en) * | 2019-07-08 | 2021-01-13 | Bayer Aktiengesellschaft | Influencing a sequential chromatography in real-time |
| EP3699697A1 (en) * | 2019-02-25 | 2020-08-26 | Bayer Aktiengesellschaft | Automated simultaneous process control |
| FR3099066B1 (fr) | 2019-07-26 | 2021-08-13 | Novasep Process | Procédé de purification d’une substance cible avec inactivation virale |
| WO2021030245A1 (en) | 2019-08-12 | 2021-02-18 | Waters Technologies Corporation | Mixer for chromatography system |
| GB201911686D0 (en) * | 2019-08-15 | 2019-10-02 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process for purifying target substances |
| GB201911685D0 (en) | 2019-08-15 | 2019-10-02 | Fujifilm Diosynth Biotechnologies Uk Ltd | Process for purifying monoclonal antibodies |
| WO2021061658A1 (en) * | 2019-09-23 | 2021-04-01 | Genzyme Corporation | Product quality attribute measurement |
| JP7388206B2 (ja) * | 2020-01-22 | 2023-11-29 | 株式会社島津製作所 | 液体クロマトグラフおよび分析方法 |
| CN113663364B (zh) * | 2020-05-14 | 2025-02-21 | 佛山汉腾生物科技有限公司 | 层析装置 |
| US11988647B2 (en) | 2020-07-07 | 2024-05-21 | Waters Technologies Corporation | Combination mixer arrangement for noise reduction in liquid chromatography |
| US11898999B2 (en) | 2020-07-07 | 2024-02-13 | Waters Technologies Corporation | Mixer for liquid chromatography |
| EP4214503A1 (en) * | 2020-09-17 | 2023-07-26 | Computational International LLC | System and method for monitoring for the presence of elements |
| US11821882B2 (en) | 2020-09-22 | 2023-11-21 | Waters Technologies Corporation | Continuous flow mixer |
| JP2022091322A (ja) * | 2020-12-09 | 2022-06-21 | 株式会社島津製作所 | 液体クロマトグラフのpH管理システムおよびプログラム |
| WO2022245566A1 (en) | 2021-05-20 | 2022-11-24 | Waters Technologies Corporation | Equal dispersion split-flow mixer |
| US12551858B2 (en) | 2021-06-23 | 2026-02-17 | Waters Technologies Corporation | Passive solvent mixer for liquid chromatography |
| WO2023165947A1 (en) * | 2022-03-03 | 2023-09-07 | Chromacon Ag | Chromatographic purification method and uses thereof |
| CN114797173A (zh) * | 2022-04-10 | 2022-07-29 | 南通星中细胞工程有限公司 | 一种用于外泌体的高效制备装置及制备方法 |
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| US3918907A (en) * | 1973-10-29 | 1975-11-11 | Beckman Instruments Inc | Micro automatic amino acid analysis process and system |
| US4246101A (en) * | 1978-12-28 | 1981-01-20 | Pure Cycle Corporation | Water recycling system |
| US4762796A (en) | 1981-10-05 | 1988-08-09 | Exxon Research And Engineering Company | pH control of a process stream |
| JPS62255865A (ja) | 1986-04-28 | 1987-11-07 | Hitachi Ltd | 液体クロマトグラフ |
| US4840730A (en) * | 1986-07-25 | 1989-06-20 | Sepragen Corporation | Chromatography system using horizontal flow columns |
| JP2581568B2 (ja) | 1987-10-08 | 1997-02-12 | 株式会社日立製作所 | イオンクロマトグラフイ装置 |
| US5114576A (en) * | 1990-02-15 | 1992-05-19 | Trineos | Prevention of contaminants buildup in captured and recirculated water systems |
| JP3175941B2 (ja) * | 1991-03-28 | 2001-06-11 | パーセプティブ バイオシステムズ インコーポレイテッド | クロマトグラフ溶出液の減法に依るオンライン生成物確認方法及び装置 |
| US5792371A (en) | 1996-08-22 | 1998-08-11 | Iosolutions Incorporated | Method of disinfecting water with iodine species |
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| JP4959565B2 (ja) * | 2004-05-21 | 2012-06-27 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 低流量動作を可能にするためのhplc定流量ポンプの閉ループ流量制御 |
| US7642306B2 (en) | 2004-06-25 | 2010-01-05 | Johns Manville | Control of pH in formaldehyde-free binder systems |
| WO2006039588A2 (en) | 2004-09-30 | 2006-04-13 | Bayer Healthcare Llc | Devices and methods for integrated continuous manufacturing of biological molecules |
| US8123949B2 (en) | 2005-01-20 | 2012-02-28 | Waters Technologies Corporation | Methods for separating compounds |
| EP1716900A1 (en) | 2005-04-29 | 2006-11-02 | Eidgenössische Technische Hochschule Zürich | Method and device for chromatographic purification |
| EP1775001A1 (en) | 2005-10-13 | 2007-04-18 | Xendo Holding B.V. | Device for chromatographic separations |
| JP4939910B2 (ja) * | 2006-11-29 | 2012-05-30 | 株式会社東芝 | マイクロ化学分析システム及びマイクロ化学分析装置 |
| JP5140721B2 (ja) | 2007-04-17 | 2013-02-13 | イクスエンド、ホールディング、ベスローテン、フェンノートシャップ | 連続メンブレン吸着方法および装置 |
| GB0709109D0 (en) | 2007-05-11 | 2007-06-20 | Enpar Technologies Inc | Wastewater ammonium extraction and electrolytic conversion to nitrogen gas |
| WO2009045897A1 (en) | 2007-10-03 | 2009-04-09 | Dyax Corp. | Systems and methods for purifying proteins |
| EP2281000A2 (en) | 2008-05-15 | 2011-02-09 | Novo Nordisk A/S | Antibody purification process |
| EP2421631B1 (en) | 2009-04-23 | 2021-05-26 | Global Life Sciences Solutions USA LLC | Chromatography system and method with feedback control for variable speed loading |
-
2009
- 2009-09-25 US US12/566,701 patent/US9527010B2/en active Active
-
2010
- 2010-09-20 CN CN201080043193.9A patent/CN102574026B/zh active Active
- 2010-09-20 IN IN1850DEN2012 patent/IN2012DN01850A/en unknown
- 2010-09-20 EP EP10819116.4A patent/EP2480305B1/en active Active
- 2010-09-20 WO PCT/SE2010/051003 patent/WO2011037522A1/en not_active Ceased
- 2010-09-20 JP JP2012530844A patent/JP5749270B2/ja active Active
- 2010-09-20 AU AU2010298768A patent/AU2010298768B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5749270B2 (ja) | 2015-07-15 |
| AU2010298768A1 (en) | 2012-03-15 |
| EP2480305B1 (en) | 2020-10-28 |
| WO2011037522A1 (en) | 2011-03-31 |
| JP2013506127A (ja) | 2013-02-21 |
| US20110073548A1 (en) | 2011-03-31 |
| US9527010B2 (en) | 2016-12-27 |
| EP2480305A1 (en) | 2012-08-01 |
| CN102574026B (zh) | 2015-10-07 |
| EP2480305A4 (en) | 2014-07-02 |
| CN102574026A (zh) | 2012-07-11 |
| AU2010298768B2 (en) | 2015-07-02 |
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