IN186170B - - Google Patents

Info

Publication number
IN186170B
IN186170B IN1574CA1998A IN186170B IN 186170 B IN186170 B IN 186170B IN 1574CA1998 A IN1574CA1998 A IN 1574CA1998A IN 186170 B IN186170 B IN 186170B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Ulf Niemeyer
Harald Niegel
Bernhard Kutscher
Ion Neda
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of IN186170B publication Critical patent/IN186170B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IN1574CA1998 1997-09-06 1998-09-01 IN186170B (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19739159A DE19739159C1 (de) 1997-09-06 1997-09-06 Verfahren zur Herstellung von Oxazaphosphorin-2-aminen

Publications (1)

Publication Number Publication Date
IN186170B true IN186170B (ko) 2001-06-30

Family

ID=7841505

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1574CA1998 IN186170B (ko) 1997-09-06 1998-09-01

Country Status (19)

Country Link
US (1) US6187941B1 (ko)
EP (1) EP1012152B1 (ko)
JP (1) JP4278859B2 (ko)
CN (1) CN1147498C (ko)
AR (1) AR013467A1 (ko)
AT (1) ATE225797T1 (ko)
BR (1) BR9814266B1 (ko)
CA (1) CA2301104C (ko)
DE (2) DE19739159C1 (ko)
DK (1) DK1012152T3 (ko)
ES (1) ES2185220T3 (ko)
HK (1) HK1030422A1 (ko)
HU (1) HU226887B1 (ko)
IL (1) IL134507A (ko)
IN (1) IN186170B (ko)
PL (1) PL190097B1 (ko)
PT (1) PT1012152E (ko)
WO (1) WO1999012942A1 (ko)
ZA (1) ZA987741B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1607204B (zh) * 2003-10-13 2011-10-26 北京大学 环磷酰胺季铵盐衍生物及其合成和应用
US20110054081A1 (en) * 2009-09-02 2011-03-03 Frank Dierschke Formulation and its use
FR2968662B1 (fr) * 2010-12-10 2013-11-22 Roussy Inst Gustave Nouveaux derives d'oxazaphosphorines pre-activees, utilisation et methode de preparation
EP3277700A1 (en) 2015-04-02 2018-02-07 Przedsi Biorstwo Produkcyjno-WDRO Eniowe Ifotam SP. Z.O.O Method of production of n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxazaphosphorine-2-amine 2-oxide
CN107936061B (zh) * 2017-12-28 2019-08-06 山东铂源药业有限公司 一种环磷酰胺的合成方法
CN109535201B (zh) * 2019-01-25 2020-04-03 连云港贵科药业有限公司 一种环磷酰胺的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE563332A (ko) * 1956-12-20
US3732340A (en) * 1966-07-11 1973-05-08 Asta Werke Ag Chem Fab N',o-propylene phosphoric acid ester diamides
DE1645921C3 (de) * 1966-07-11 1978-10-12 Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld 2-Oxo-13,2-osazaphosphorinane, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
GB1235022A (en) * 1969-06-04 1971-06-09 Laeaeke Ag A new method for the production of cyclophosphamide
JPS54157580A (en) * 1978-05-29 1979-12-12 Otsuka Pharmaceut Co Ltd Optically active oxazaphosphorine derivative
JPS54157581A (en) * 1978-05-29 1979-12-12 Otsuka Pharmaceut Co Ltd Oxazaphosphorine derivative
PL119971B1 (en) * 1978-11-06 1982-02-27 Polska Akad Nauk Centrum Process for preparing optically active derivatives of 1,3,2-oxazaphosphorinane,2-oksazofosforinata
JPS5826919B2 (ja) * 1978-11-07 1983-06-06 大塚製薬株式会社 シクロ↓−１，３，２↓−オキサアザホスホル誘導体の製造法
JPS5931787A (ja) * 1982-08-13 1984-02-20 Otsuka Pharmaceut Co Ltd １，３，２−オキサアザホスホリナン−２−オキシド誘導体
PL149593B1 (pl) * 1986-12-18 1990-02-28 Sposób wytwarzania n-acylowych pochodnych 1 , 3 , 2-oksazafosforinanu

Also Published As

Publication number Publication date
CN1147498C (zh) 2004-04-28
HUP0003496A3 (en) 2002-12-28
PL190097B1 (pl) 2005-10-31
EP1012152B1 (de) 2002-10-09
JP2001515910A (ja) 2001-09-25
DE19739159C1 (de) 1999-01-28
US6187941B1 (en) 2001-02-13
HUP0003496A2 (hu) 2002-11-28
IL134507A0 (en) 2001-04-30
BR9814266A (pt) 2001-10-09
PL339188A1 (en) 2000-12-04
WO1999012942A1 (de) 1999-03-18
CN1268950A (zh) 2000-10-04
DE59805920D1 (de) 2002-11-14
ZA987741B (en) 1998-10-08
ES2185220T3 (es) 2003-04-16
EP1012152A1 (de) 2000-06-28
DK1012152T3 (da) 2003-02-10
PT1012152E (pt) 2003-02-28
JP4278859B2 (ja) 2009-06-17
CA2301104C (en) 2009-10-20
IL134507A (en) 2004-06-20
HU226887B1 (en) 2010-01-28
HK1030422A1 (en) 2001-05-04
ATE225797T1 (de) 2002-10-15
BR9814266B1 (pt) 2009-05-05
AR013467A1 (es) 2000-12-27
CA2301104A1 (en) 1999-03-18

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