IN176319B - - Google Patents

Info

Publication number
IN176319B
IN176319B IN431CA1993A IN176319B IN 176319 B IN176319 B IN 176319B IN 431CA1993 A IN431CA1993 A IN 431CA1993A IN 176319 B IN176319 B IN 176319B
Authority
IN
India
Prior art keywords
amino group
amidase
penicillin
protected
group
Prior art date
Application number
Other languages
English (en)
Inventor
Maurizio Zenoni
Claudio Fuganti
Original Assignee
Finpael Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finpael Spa filed Critical Finpael Spa
Publication of IN176319B publication Critical patent/IN176319B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IN431CA1993 1992-08-07 1993-08-02 IN176319B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929216759A GB9216759D0 (en) 1992-08-07 1992-08-07 Process for the production of 7-amino thiazolyl cephalosporins

Publications (1)

Publication Number Publication Date
IN176319B true IN176319B (zh) 1996-04-20

Family

ID=10719967

Family Applications (1)

Application Number Title Priority Date Filing Date
IN431CA1993 IN176319B (zh) 1992-08-07 1993-08-02

Country Status (24)

Country Link
US (2) US5441874A (zh)
EP (1) EP0582102B1 (zh)
JP (1) JPH06172364A (zh)
KR (1) KR100268959B1 (zh)
CN (1) CN1045297C (zh)
AT (1) ATE161052T1 (zh)
AU (1) AU658761B2 (zh)
BR (1) BR9303272A (zh)
CA (1) CA2103696A1 (zh)
DE (1) DE69315634T2 (zh)
DK (1) DK0582102T3 (zh)
ES (1) ES2110032T3 (zh)
FI (1) FI933486A (zh)
GB (1) GB9216759D0 (zh)
GR (1) GR3025807T3 (zh)
HU (1) HUT64962A (zh)
IL (1) IL106574A (zh)
IN (1) IN176319B (zh)
MX (1) MX9304790A (zh)
NZ (1) NZ248307A (zh)
PL (1) PL299946A1 (zh)
RU (1) RU2109017C1 (zh)
TW (1) TW242627B (zh)
ZA (1) ZA935688B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100345847B1 (ko) * 1994-08-13 2002-12-16 제일제당주식회사 고정화효소에의한세파졸린의제조방법
IT1295935B1 (it) 1997-10-30 1999-05-28 Acs Dobfar Spa Derivati aminotiazolici utili nella preparazione di antibiotici b -lattamici
KR19990045922A (ko) * 1999-02-13 1999-06-25 오판원 여화용통굽스폰지신발창의제조방법
EP1704153A2 (en) * 2004-01-16 2006-09-27 Wockhardt Limited Improved process for the production of cefotaxime sodium
WO2006008749A1 (en) * 2004-07-16 2006-01-26 Hetero Drugs Limited Process for preparing pure cephalosporine intermediates
WO2007013043A2 (en) * 2005-07-29 2007-02-01 Ranbaxy Laboratories Limited Processes for the preparation of 7-amino-3-vinyl cephalosporanic acid
KR100760429B1 (ko) * 2006-03-03 2007-10-04 한미약품 주식회사 세팔로스포린 제조용 중간체로 사용되는2-아미노티아졸-4-일 아세틸클로라이드 염산염의 개선된제조방법
CN101045733B (zh) * 2007-01-26 2011-11-16 浙江永宁药业股份有限公司 一种头孢替安盐酸盐制备方法
CN103012432B (zh) * 2012-12-04 2015-06-03 山东鑫泉医药有限公司 高纯度头孢替安中间体盐酸盐的制备方法
CN103601737B (zh) * 2013-12-04 2016-02-03 哈药集团制药总厂 一种盐酸头孢替安的制备方法
CN104356146B (zh) * 2014-11-14 2016-09-14 浙江浙邦制药有限公司 一种头孢替安盐酸盐的制备方法
CN109336906B (zh) * 2018-11-21 2020-05-22 山东罗欣药业集团股份有限公司 一种头孢替安盐酸盐干燥工艺

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4948760B1 (zh) * 1970-12-25 1974-12-23
DE2355078A1 (de) * 1973-11-03 1975-05-07 Bayer Ag Verfahren zur herstellung von 7-amino-delta hoch 3-cephem-derivaten
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
GB1476981A (en) * 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids
US4091245A (en) * 1974-06-26 1978-05-23 Toyota Jidosha Kogyo Kabushiki Kaisha Distributor electrode assembly having outer resistive layer for suppressing noise
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
US4507487A (en) * 1982-09-23 1985-03-26 Bristol-Myers Company Chemical compounds
ZA874696B (en) * 1986-07-03 1988-01-04 F. Hoffmann-La Roche & Co. Aktiengesellschaft Acyl derivatives
ATE212027T1 (de) * 1988-03-16 2002-02-15 Eisai Co Ltd Cephemderivate und verfahren zu ihrer herstellung
NZ230921A (en) * 1988-10-07 1990-07-26 Sankyo Co 3-phenyloxymethyl-cephalosporin derivatives and medicaments
AU649275B2 (en) * 1990-11-06 1994-05-19 Bristol-Myers Squibb Company Prodrugs for beta-lactamase and uses thereof
EP0508375A3 (en) * 1991-04-12 1992-12-09 Lucky Ltd. Novel cephalosporin compounds and processes for preparation thereof

Also Published As

Publication number Publication date
KR940005634A (ko) 1994-03-22
NZ248307A (en) 1994-10-26
PL299946A1 (en) 1994-02-21
JPH06172364A (ja) 1994-06-21
MX9304790A (es) 1994-05-31
HU9302292D0 (en) 1993-10-28
US5654425A (en) 1997-08-05
CN1082610A (zh) 1994-02-23
ZA935688B (en) 1994-04-12
FI933486A (fi) 1994-02-08
EP0582102B1 (en) 1997-12-10
KR100268959B1 (en) 2000-10-16
CA2103696A1 (en) 1994-02-08
DE69315634T2 (de) 1998-04-02
AU658761B2 (en) 1995-04-27
IL106574A0 (en) 1993-12-08
AU4445293A (en) 1994-02-10
IL106574A (en) 1999-11-30
BR9303272A (pt) 1994-03-08
ES2110032T3 (es) 1998-02-01
EP0582102A2 (en) 1994-02-09
ATE161052T1 (de) 1997-12-15
EP0582102A3 (en) 1994-05-18
TW242627B (zh) 1995-03-11
FI933486A0 (fi) 1993-08-06
GB9216759D0 (en) 1992-09-23
RU2109017C1 (ru) 1998-04-20
US5441874A (en) 1995-08-15
CN1045297C (zh) 1999-09-29
HUT64962A (en) 1994-03-28
DE69315634D1 (de) 1998-01-22
GR3025807T3 (en) 1998-03-31
DK0582102T3 (da) 1998-08-24

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