IL99761A0 - Purified immunoglobulins,their preparation and pharmaceutical compositions containing them - Google Patents

Purified immunoglobulins,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL99761A0
IL99761A0 IL99761A IL9976191A IL99761A0 IL 99761 A0 IL99761 A0 IL 99761A0 IL 99761 A IL99761 A IL 99761A IL 9976191 A IL9976191 A IL 9976191A IL 99761 A0 IL99761 A0 IL 99761A0
Authority
IL
Israel
Prior art keywords
antibody
column
prepn
cdw52
purified
Prior art date
Application number
IL99761A
Other languages
English (en)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10683866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL99761(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to IL102726A priority Critical patent/IL102726A0/xx
Publication of IL99761A0 publication Critical patent/IL99761A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2893—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD52
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL99761A 1990-10-17 1991-10-16 Purified immunoglobulins,their preparation and pharmaceutical compositions containing them IL99761A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL102726A IL102726A0 (en) 1990-10-17 1992-08-04 Purified immunoglobulins,their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909022547A GB9022547D0 (en) 1990-10-17 1990-10-17 Purified immunoglobulin

Publications (1)

Publication Number Publication Date
IL99761A0 true IL99761A0 (en) 1992-08-18

Family

ID=10683866

Family Applications (3)

Application Number Title Priority Date Filing Date
IL10272691A IL102726A (en) 1990-10-17 1991-10-16 Refined immunoglobulins, their preparation and pharmaceutical preparations containing them
IL99761A IL99761A0 (en) 1990-10-17 1991-10-16 Purified immunoglobulins,their preparation and pharmaceutical compositions containing them
IL102726A IL102726A0 (en) 1990-10-17 1992-08-04 Purified immunoglobulins,their preparation and pharmaceutical compositions containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL10272691A IL102726A (en) 1990-10-17 1991-10-16 Refined immunoglobulins, their preparation and pharmaceutical preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL102726A IL102726A0 (en) 1990-10-17 1992-08-04 Purified immunoglobulins,their preparation and pharmaceutical compositions containing them

Country Status (29)

Country Link
US (1) US5644036A (ko)
EP (1) EP0504363B2 (ko)
JP (1) JP2638680B2 (ko)
KR (2) KR960015399B1 (ko)
AT (2) ATA900791A (ko)
AU (3) AU658926B2 (ko)
BE (1) BE1004226A5 (ko)
BR (1) BR1100358A (ko)
CA (1) CA2069481C (ko)
CH (2) CH681455A5 (ko)
DE (1) DE69128774T3 (ko)
DK (1) DK0504363T4 (ko)
ES (2) ES2081742B1 (ko)
FI (2) FI110003B (ko)
FR (2) FR2668164A1 (ko)
GB (2) GB9022547D0 (ko)
GR (3) GR910100425A (ko)
HU (1) HUT64601A (ko)
IE (1) IE913560A1 (ko)
IL (3) IL102726A (ko)
IT (1) IT1250064B (ko)
LU (1) LU88122A1 (ko)
MX (1) MX9203794A (ko)
MY (2) MY119030A (ko)
NZ (2) NZ240247A (ko)
PT (2) PT99248B (ko)
TW (1) TW283710B (ko)
WO (1) WO1992007084A1 (ko)
ZA (2) ZA918259B (ko)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
IL103418A (en) * 1991-10-15 1997-11-20 Wellcome Found Therapeutic agent for the t-cell mediated inflammation of the joints and its production
GB9125768D0 (en) * 1991-12-04 1992-02-05 Hale Geoffrey Therapeutic method
GB9300501D0 (en) * 1993-01-09 1993-03-03 Wellcome Found Purification of immunoglobulin
JPH11510151A (ja) † 1995-08-01 1999-09-07 パストゥール メリユ セリュム エ ヴァサン ソシエテ アノニム 日本脳炎ワクチンの工業的製造方法と、それによって得られるワクチン
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
NZ576716A (en) 1996-02-09 2011-02-25 Abbott Biotech Ltd Human antibodies that bind human TNFalpha
GB9603256D0 (en) * 1996-02-16 1996-04-17 Wellcome Found Antibodies
US20030023043A1 (en) * 2000-03-02 2003-01-30 Kazuhisa Uchida Method of separating and purifying protein
US7332289B2 (en) 2001-03-09 2008-02-19 Chugai Seiyaku Kabushiki Kaisha Method of purifying protein
NZ530025A (en) * 2001-06-05 2005-06-24 Inst Genetics Llc Methods for purifying highly anionic proteins
GB0220894D0 (en) * 2002-09-09 2002-10-16 Millipore Uk Ltd Method of separation
CN100522989C (zh) 2002-09-11 2009-08-05 中外制药株式会社 纯化蛋白质的方法
JP5116971B2 (ja) 2002-10-15 2013-01-09 インターセル アーゲー Ｂ群連鎖球菌の接着因子をコードする核酸、ｂ群連鎖球菌の接着因子、およびその使用
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
US20070286857A1 (en) * 2003-12-22 2007-12-13 Genzyme Corporation Anti-Cd52 Antibody Treatment for Diabetes
PT1869065T (pt) * 2005-03-11 2020-06-18 Wyeth Llc Método de cromatografia de partição fraca
MX2010011184A (es) 2008-04-11 2011-01-20 Chugai Pharmaceutical Co Ltd Molecula de union de antigeno capaz de unir repetidamente a dos o mas moleculas de antigeno.
CA2939492C (en) 2009-05-13 2019-03-19 Genzyme Corporation Anti-human cd52 immunoglobulins
US9617343B2 (en) 2009-05-13 2017-04-11 Genzyme Corporation Methods and compositions for treating lupus
WO2011090719A2 (en) * 2009-12-29 2011-07-28 Dr. Reddy's Laboratories Ltd. Protein purification by ion exchange
US20130096284A1 (en) 2010-06-21 2013-04-18 Kyowa Hakko Kirin Co., Ltd. Method for purifying protein using amino acid
RU2467783C2 (ru) * 2010-07-30 2012-11-27 Закрытое акционерное общество "БиоХимМак СТ" Способ хроматографического выделения иммуноглобулина
CN108715614A (zh) 2010-11-30 2018-10-30 中外制药株式会社 与多分子的抗原重复结合的抗原结合分子
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
GB201109238D0 (en) * 2011-06-01 2011-07-13 Antitope Ltd Antibodies
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
US9650411B2 (en) 2012-08-07 2017-05-16 Kyowa Hakko Kirin Co., Ltd. Method of purifying protein
CA2883272A1 (en) 2012-09-02 2014-03-06 Abbvie Inc. Methods to control protein heterogeneity
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
AU2013381687A1 (en) 2013-03-12 2015-09-24 Abbvie Inc. Human antibodies that bind human TNF-alpha and methods of preparing the same
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
AR095199A1 (es) 2013-03-15 2015-09-30 Genzyme Corp Anticuerpos anti-cd52
EP3052640A2 (en) 2013-10-04 2016-08-10 AbbVie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
BR112016014824A2 (pt) 2013-12-27 2017-09-19 Chugai Pharmaceutical Co Ltd Método para purificar anticorpo que tem ponto isoelétrico baixo
KR101860280B1 (ko) 2014-12-19 2018-05-21 추가이 세이야쿠 가부시키가이샤 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
WO2017022651A1 (ja) 2015-07-31 2017-02-09 中外製薬株式会社 アニオン性ポリマーによる抗体を含有する組成物の精製方法
KR102359192B1 (ko) 2016-07-25 2022-02-04 세파론, 인코포레이티드 친화성 크로마토그래피 세정 완충액
EP3494991A4 (en) 2016-08-05 2020-07-29 Chugai Seiyaku Kabushiki Kaisha COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATING TO IL-8
JP7273142B2 (ja) 2019-03-29 2023-05-12 旭化成メディカル株式会社 タンパク質の精製方法
CN113692420B (zh) 2019-04-08 2023-09-12 旭化成医疗株式会社 用于纯化含蛋白质的溶液的聚酰胺介质及其制造方法
MX2021012251A (es) 2019-04-10 2021-11-12 Chugai Pharmaceutical Co Ltd Metodo para purificar un anticuerpo modificado en la region de fragmento cristalizable (fc).
KR20240021151A (ko) 2021-06-10 2024-02-16 미쯔비시 케미컬 주식회사 합성 흡착제, 항체의 정제 방법 및 항체의 제조 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
EP0328404B1 (en) * 1988-02-12 1993-09-29 Btg International Limited Modified antibodies

Also Published As

Publication number Publication date
KR960015399B1 (ko) 1996-11-13
DK0504363T4 (da) 2007-05-29
ES2081742B1 (es) 1996-10-01
JPH05504579A (ja) 1993-07-15
ES2112865T3 (es) 1998-04-16
GB9022547D0 (en) 1990-11-28
FI922824A0 (fi) 1992-06-17
HUT64601A (en) 1994-01-28
ES2081742A1 (es) 1996-03-01
KR920703108A (ko) 1992-12-17
ATA900791A (de) 1996-06-15
PT100988A (pt) 1994-02-28
FI110003B (fi) 2002-11-15
DE69128774D1 (de) 1998-02-26
KR100193314B1 (ko) 1999-06-15
GB2253397A (en) 1992-09-09
ATE162552T1 (de) 1998-02-15
GR920100471A (el) 1994-06-30
GB9209529D0 (en) 1992-07-01
MY119030A (en) 2005-03-31
EP0504363B2 (en) 2007-02-07
FR2668164A1 (fr) 1992-04-24
MY136210A (en) 2008-08-29
EP0504363B1 (en) 1998-01-21
ZA926191B (en) 1993-04-16
IL102726A (en) 2002-08-14
FI110002B (fi) 2002-11-15
IT1250064B (it) 1995-03-30
FR2668164B1 (ko) 1995-04-14
FR2677997A1 (fr) 1992-12-24
JP2638680B2 (ja) 1997-08-06
PT99248B (pt) 1999-04-30
BE1004226A5 (fr) 1992-10-13
AU649078B2 (en) 1994-05-12
AU658926B2 (en) 1995-05-04
EP0504363A1 (en) 1992-09-23
AU8729491A (en) 1992-05-20
DE69128774T3 (de) 2007-08-16
IE913560A1 (en) 1992-04-22
IL102726A0 (en) 1993-01-31
BR1100358A (pt) 2000-03-28
AU4521897A (en) 1998-02-12
PT100988B (pt) 1999-08-31
NZ240247A (en) 1994-03-25
AU7024294A (en) 1995-01-05
AU2532192A (en) 1993-02-11
CA2069481C (en) 2003-07-29
US5644036A (en) 1997-07-01
FI922380A (fi) 1992-05-25
CA2069481A1 (en) 1992-04-18
ES2112865T5 (es) 2007-09-16
DE69128774T2 (de) 1998-06-04
ITRM910788A1 (it) 1993-04-16
PT99248A (pt) 1993-06-30
TW283710B (ko) 1996-08-21
CH681305A5 (ko) 1993-02-26
ITRM910788A0 (it) 1991-10-16
GR910100425A (el) 1992-09-25
MX9203794A (es) 1992-07-01
LU88122A1 (fr) 1993-03-15
DK0504363T3 (da) 1998-09-21
FI922824A (fi) 1992-06-17
HU9202000D0 (en) 1992-10-28
FI922380A0 (fi) 1992-05-25
NZ244114A (en) 1995-06-27
GR3026588T3 (en) 1998-07-31
AU716402B2 (en) 2000-02-24
WO1992007084A1 (en) 1992-04-30
ZA918259B (en) 1993-04-16
CH681455A5 (ko) 1993-03-31

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