IL99248A - Acid esters 01-) 1-Hydroxyethyl (-11-oxo-1-azatricycloundec-2-n-2-carboxylic acid, their preparation and pharmaceutical preparations - Google Patents

Acid esters 01-) 1-Hydroxyethyl (-11-oxo-1-azatricycloundec-2-n-2-carboxylic acid, their preparation and pharmaceutical preparations

Info

Publication number
IL99248A
IL99248A IL9924891A IL9924891A IL99248A IL 99248 A IL99248 A IL 99248A IL 9924891 A IL9924891 A IL 9924891A IL 9924891 A IL9924891 A IL 9924891A IL 99248 A IL99248 A IL 99248A
Authority
IL
Israel
Prior art keywords
group
methoxy
compounds
alkyl
compound
Prior art date
Application number
IL9924891A
Other languages
English (en)
Hebrew (he)
Other versions
IL99248A0 (en
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909018330A external-priority patent/GB9018330D0/en
Priority claimed from GB919104770A external-priority patent/GB9104770D0/en
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of IL99248A0 publication Critical patent/IL99248A0/xx
Publication of IL99248A publication Critical patent/IL99248A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL9924891A 1990-08-21 1991-08-20 Acid esters 01-) 1-Hydroxyethyl (-11-oxo-1-azatricycloundec-2-n-2-carboxylic acid, their preparation and pharmaceutical preparations IL99248A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909018330A GB9018330D0 (en) 1990-08-21 1990-08-21 Heterocyclic compounds
GB919104770A GB9104770D0 (en) 1991-03-07 1991-03-07 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
IL99248A0 IL99248A0 (en) 1992-07-15
IL99248A true IL99248A (en) 1996-01-31

Family

ID=26297540

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9924891A IL99248A (en) 1990-08-21 1991-08-20 Acid esters 01-) 1-Hydroxyethyl (-11-oxo-1-azatricycloundec-2-n-2-carboxylic acid, their preparation and pharmaceutical preparations

Country Status (32)

Country Link
US (1) US5587374A (de)
EP (1) EP0495953B1 (de)
JP (2) JP3151215B2 (de)
KR (1) KR0169147B1 (de)
CN (1) CN1030917C (de)
AP (1) AP238A (de)
AT (1) ATE106887T1 (de)
AU (1) AU647178B2 (de)
CA (1) CA2067741C (de)
CY (1) CY2037A (de)
CZ (1) CZ280942B6 (de)
DE (1) DE69102415T2 (de)
DK (1) DK0495953T3 (de)
ES (1) ES2054502T3 (de)
FI (1) FI97136C (de)
HK (1) HK19495A (de)
HR (1) HRP940556B1 (de)
HU (2) HUT61024A (de)
IE (1) IE66122B1 (de)
IL (1) IL99248A (de)
MX (1) MX9100743A (de)
MY (1) MY106997A (de)
NO (1) NO300176B1 (de)
NZ (1) NZ239474A (de)
OA (1) OA09578A (de)
PL (1) PL169425B1 (de)
PT (1) PT98729B (de)
SG (1) SG169494G (de)
SI (1) SI9111427B (de)
SK (1) SK278470B6 (de)
WO (1) WO1992003437A1 (de)
YU (1) YU48079B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
AP294A (en) * 1992-08-31 1993-12-28 Glaxo Spa "10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8) undec-2-ene-2-carboxylic acid derivatives".
GB9218781D0 (en) * 1992-09-04 1992-10-21 Glaxo Spa Heterocyclic derivatives
IN188720B (de) * 1997-11-06 2002-11-02 Panacea Biotec Ltd
KR100945706B1 (ko) * 2001-11-05 2010-03-05 다이닛본 스미토모 세이야꾸 가부시끼가이샤 신규 카르바페넴 화합물
CA2519794A1 (en) * 2003-04-08 2004-10-21 Sumitomo Pharmaceuticals Co., Ltd. Novel carbapenem compounds
CA2577924A1 (en) * 2004-09-03 2006-03-09 Dainippon Sumitomo Pharma Co., Ltd. Novel carbapenem compound
JPWO2006103999A1 (ja) * 2005-03-25 2008-09-04 大日本住友製薬株式会社 新規なカルバペネム化合物
EP2085084A1 (de) 2008-01-29 2009-08-05 LEK Pharmaceuticals D.D. Verwendung eines Hemmers von Beta-Lactamasen und dessen Kombination mit Beta-Lactam-Antibiotika
EP2135871A1 (de) * 2008-06-18 2009-12-23 LEK Pharmaceuticals D.D. Neuartige Trinemantibiotika und Hemmer von Beta-Lactamasen
RU2757272C2 (ru) 2017-05-08 2021-10-12 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Санфетринем или его соль или сложный эфир для применения при лечении микобактериальной инфекции

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425571A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephaosporins
GB1433131A (en) * 1972-03-13 1976-04-22 Astra Laekemedel Ab Penicillins
DE2811514A1 (de) * 1977-03-19 1978-09-21 Beecham Group Ltd Ester der 7-oxo-1-azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept- 2-en-2-carbonsaeure und deren derivate, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zubereitungen
US4374849A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-Amidocyclonocardicins
US4374848A (en) * 1981-09-14 1983-02-22 Merck & Co., Inc. 6-(1-Hydroxyethyl)cyclonocardicin
CZ435990A3 (cs) * 1989-09-08 1999-11-17 Glaxo S.P.A. Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
AU636913B2 (en) * 1989-10-11 1993-05-13 Takeda Chemical Industries Ltd. Tricyclic carbapenem compounds
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
GB9104832D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
AU647178B2 (en) 1994-03-17
MY106997A (en) 1995-08-30
EP0495953B1 (de) 1994-06-08
FI921717A0 (fi) 1992-04-16
FI97136B (fi) 1996-07-15
NO921521L (no) 1992-06-22
IE912944A1 (en) 1992-02-26
DE69102415T2 (de) 1994-10-13
SI9111427B (sl) 2000-10-31
NO921521D0 (no) 1992-04-15
YU142791A (sh) 1994-01-20
HU211584A9 (en) 1995-12-28
IL99248A0 (en) 1992-07-15
AP9100320A0 (en) 1991-10-31
MX9100743A (es) 1992-04-01
AU8421291A (en) 1992-03-17
SK121392A3 (en) 1997-06-04
KR0169147B1 (en) 1999-01-15
JP3151215B2 (ja) 2001-04-03
PT98729A (pt) 1992-07-31
HUT61024A (en) 1992-11-30
OA09578A (en) 1993-01-31
JP3461786B2 (ja) 2003-10-27
CZ280942B6 (cs) 1996-05-15
IE66122B1 (en) 1995-12-13
HRP940556B1 (en) 2000-06-30
CZ121392A3 (en) 1993-04-14
HK19495A (en) 1995-02-17
ATE106887T1 (de) 1994-06-15
FI921717A (fi) 1992-04-16
JP2000351730A (ja) 2000-12-19
SG169494G (en) 1995-04-28
JPH05502044A (ja) 1993-04-15
WO1992003437A1 (en) 1992-03-05
DK0495953T3 (da) 1994-07-18
US5587374A (en) 1996-12-24
YU48079B (sh) 1997-01-08
ES2054502T3 (es) 1994-08-01
DE69102415D1 (de) 1994-07-14
KR920702361A (ko) 1992-09-03
NZ239474A (en) 1994-06-27
HRP940556A2 (en) 1996-06-30
CY2037A (en) 1998-02-20
CN1030917C (zh) 1996-02-07
NO300176B1 (no) 1997-04-21
CN1060094A (zh) 1992-04-08
SI9111427A (en) 1996-12-31
PL169425B1 (pl) 1996-07-31
CA2067741A1 (en) 1992-02-22
AP238A (en) 1993-02-04
HU9201303D0 (en) 1992-07-28
FI97136C (fi) 1996-10-25
PT98729B (pt) 1999-01-29
SK278470B6 (en) 1997-06-04
CA2067741C (en) 2002-01-01
EP0495953A1 (de) 1992-07-29

Similar Documents

Publication Publication Date Title
US5407931A (en) Derivatives of 1-azatricyclo[7.2.03,8]undec-2-ene-2-carboxyclic acid
US4289696A (en) Polycyclic compounds
US4234596A (en) 3-(2-Aminoethylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
EP0495953B1 (de) Ester der 10-(1-Hydroxy-äthyl)-11-oxo-1-azatricyclo[7.2.0.0(3,8)]undec-2-ene-2-carbonsäure und deren Derivate und Verfahren zu ihrer Herstellung
EP0045198A2 (de) 1,1-Disubstituierte Carba-2-peneme und ihre Herstellung
AU660658B2 (en) Antibacterial condensed carbapenemes
Perboni et al. 10 (1-hydroxyethyl)-11-oxo-1-azatricyclo/7.2. 0.0. 3. 8/undec-2-ene-2-carboxylic acid esters and a process for preparing thereof
EP0502465A1 (de) Ester von antibakteriellen kondensierten Carbapenemderivaten
RU2043354C1 (ru) Эфиры 10(1- гидроксиэтил) -11-оксо-1-азатрицикло [7,2,0,03,8]ундец-2-ен-2-карбоновой кислоты и способ их получения
CZ185193A3 (en) Heterocyclic derivatives, process of their preparation and pharmaceutical preparations in which they are comprised
GB2105329A (en) Penem-3-carboxylic acid derivatives their preparation and their use as antimicrobial agents
AP294A (en) "10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo-(7.2.0.0.3.8) undec-2-ene-2-carboxylic acid derivatives".
EP0656899A1 (de) Kondensierte carbapenemderivate
EP0126780A1 (de) Carbapenemverbindung

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees