IL98914A - Process for the preparation of 6-(substituted aminopropionyl) derivatives of forskolin and intermediates used in such process - Google Patents

Process for the preparation of 6-(substituted aminopropionyl) derivatives of forskolin and intermediates used in such process

Info

Publication number
IL98914A
IL98914A IL9891491A IL9891491A IL98914A IL 98914 A IL98914 A IL 98914A IL 9891491 A IL9891491 A IL 9891491A IL 9891491 A IL9891491 A IL 9891491A IL 98914 A IL98914 A IL 98914A
Authority
IL
Israel
Prior art keywords
derivatives
aminopropionyl
forskolin
substituted
preparation
Prior art date
Application number
IL9891491A
Other languages
English (en)
Other versions
IL98914A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL98914A0 publication Critical patent/IL98914A0/xx
Publication of IL98914A publication Critical patent/IL98914A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
IL9891491A 1990-07-24 1991-07-22 Process for the preparation of 6-(substituted aminopropionyl) derivatives of forskolin and intermediates used in such process IL98914A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90114124 1990-07-24

Publications (2)

Publication Number Publication Date
IL98914A0 IL98914A0 (en) 1992-07-15
IL98914A true IL98914A (en) 1997-01-10

Family

ID=8204249

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9891491A IL98914A (en) 1990-07-24 1991-07-22 Process for the preparation of 6-(substituted aminopropionyl) derivatives of forskolin and intermediates used in such process

Country Status (23)

Country Link
US (1) US5869523A (es)
EP (1) EP0468445B1 (es)
JP (1) JPH04279577A (es)
KR (1) KR0173317B1 (es)
CN (1) CN1033583C (es)
AT (1) ATE132863T1 (es)
AU (1) AU642754B2 (es)
CA (1) CA2047617A1 (es)
CZ (1) CZ281393B6 (es)
DE (1) DE69116251T2 (es)
DK (1) DK0468445T3 (es)
ES (1) ES2082890T3 (es)
FI (1) FI913506A (es)
GR (1) GR3018642T3 (es)
HU (1) HU208966B (es)
IE (1) IE74140B1 (es)
IL (1) IL98914A (es)
MX (1) MX9100345A (es)
MY (1) MY106512A (es)
PL (1) PL167626B1 (es)
RU (1) RU2045523C1 (es)
YU (1) YU48634B (es)
ZA (1) ZA915763B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250682A (en) * 1990-07-24 1993-10-05 Hoechst Aktiengesellschaft Process for the preparation of 6-[3-substitutedaminopropionyl]-7-deacetylforskolin derivatives
PL170900B1 (pl) * 1990-11-01 1997-02-28 Nippon Kayaku Kk Sposób wytwarzania 6-(3-dwumetyloaminopropionylo)-forskolinu PL PL PL
US7334636B2 (en) * 2005-02-08 2008-02-26 Halliburton Energy Services, Inc. Methods of creating high-porosity propped fractures using reticulated foam
CN113226304B (zh) * 2018-12-29 2023-03-24 上海明隽生物技术有限公司 免疫抑制药物组合物及其应用
CN117586217B (zh) * 2024-01-17 2024-03-19 云南省药物研究所 一种基于国产毛喉鞘蕊花的佛司可林制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623300A1 (de) * 1986-07-11 1988-01-21 Hoechst Ag 7-acyloxy-6-aminoacyloxypolyoxylabdane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
FR2614891B1 (fr) * 1987-05-04 1991-05-24 Roussel Uclaf Nouveaux derives de la forskoline, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant ainsi que des intermediaires de leur procede de preparation
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation
US5250682A (en) * 1990-07-24 1993-10-05 Hoechst Aktiengesellschaft Process for the preparation of 6-[3-substitutedaminopropionyl]-7-deacetylforskolin derivatives

Also Published As

Publication number Publication date
MX9100345A (es) 1992-02-28
CA2047617A1 (en) 1992-01-25
DE69116251T2 (de) 1996-07-04
IL98914A0 (en) 1992-07-15
YU48634B (sh) 1999-03-04
HUT58715A (en) 1992-03-30
CS231391A3 (en) 1992-02-19
ATE132863T1 (de) 1996-01-15
ZA915763B (en) 1992-04-29
IE912592A1 (en) 1992-01-29
CN1033583C (zh) 1996-12-18
EP0468445A1 (en) 1992-01-29
AU8120891A (en) 1992-07-02
DE69116251D1 (de) 1996-02-22
CZ281393B6 (cs) 1996-09-11
HU912489D0 (en) 1991-12-30
DK0468445T3 (da) 1996-05-20
GR3018642T3 (en) 1996-04-30
JPH04279577A (ja) 1992-10-05
FI913506A0 (fi) 1991-07-22
AU642754B2 (en) 1993-10-28
RU2045523C1 (ru) 1995-10-10
CN1058403A (zh) 1992-02-05
MY106512A (en) 1995-06-30
US5869523A (en) 1999-02-09
PL167626B1 (pl) 1995-10-31
IE74140B1 (en) 1997-07-02
ES2082890T3 (es) 1996-04-01
YU128591A (sh) 1994-09-09
KR0173317B1 (ko) 1999-02-01
KR920002573A (ko) 1992-02-28
HU208966B (en) 1994-02-28
EP0468445B1 (en) 1996-01-10
PL291199A1 (en) 1992-03-09
FI913506A (fi) 1992-01-25

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed