IL98191A - תהליך להכנה אננטיוסלקטיבית של תולדות פנילאיזוסרין - Google Patents

תהליך להכנה אננטיוסלקטיבית של תולדות פנילאיזוסרין

Info

Publication number
IL98191A
IL98191A IL9819191A IL9819191A IL98191A IL 98191 A IL98191 A IL 98191A IL 9819191 A IL9819191 A IL 9819191A IL 9819191 A IL9819191 A IL 9819191A IL 98191 A IL98191 A IL 98191A
Authority
IL
Israel
Prior art keywords
formula
phenyl
process according
group
mmol
Prior art date
Application number
IL9819191A
Other languages
English (en)
Other versions
IL98191A0 (en
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of IL98191A0 publication Critical patent/IL98191A0/xx
Publication of IL98191A publication Critical patent/IL98191A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Control Of Transmission Device (AREA)
  • Measuring Fluid Pressure (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL9819191A 1990-05-22 1991-05-20 תהליך להכנה אננטיוסלקטיבית של תולדות פנילאיזוסרין IL98191A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9006369A FR2662441B1 (fr) 1990-05-22 1990-05-22 Procede de preparation enantioselective de derives de la phenylisoserine.

Publications (2)

Publication Number Publication Date
IL98191A0 IL98191A0 (en) 1992-06-21
IL98191A true IL98191A (he) 1995-12-31

Family

ID=9396839

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9819191A IL98191A (he) 1990-05-22 1991-05-20 תהליך להכנה אננטיוסלקטיבית של תולדות פנילאיזוסרין

Country Status (23)

Country Link
US (1) US5292921A (he)
EP (1) EP0530285B1 (he)
JP (1) JPH05506446A (he)
AT (1) ATE109768T1 (he)
AU (1) AU647490B2 (he)
CA (1) CA2079314A1 (he)
CZ (1) CZ280087B6 (he)
DE (1) DE69103413T2 (he)
DK (1) DK0530285T3 (he)
ES (1) ES2057898T3 (he)
FI (1) FI924569A (he)
FR (1) FR2662441B1 (he)
HU (1) HU210187B (he)
IE (1) IE64687B1 (he)
IL (1) IL98191A (he)
NO (1) NO179943C (he)
NZ (1) NZ238207A (he)
PT (1) PT97746B (he)
RU (1) RU2086538C1 (he)
SK (1) SK277926B6 (he)
WO (1) WO1991017976A1 (he)
YU (1) YU89791A (he)
ZA (1) ZA913827B (he)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658510B1 (fr) * 1990-02-21 1992-04-30 Rhone Poulenc Sante Nouveau derive de la beta-phenylisoserine, sa preparation et son emploi.
FR2680506B1 (fr) * 1991-08-19 1994-09-02 Rhone Poulenc Rorer Sa Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
US5739362A (en) * 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
FR2696454B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation stéréosélective d'un dérivé de la beta-phénylisosérine et son utilisation pour la préparation de dérivés du Taxane.
IL107950A (he) 1992-12-15 2001-04-30 Upjohn Co b 7, b 8 - מתאנו - טקסולים, הכנתם ותכשירי רוקחות נגד גידולים ממאירים המכילים אותם
IT1261667B (it) * 1993-05-20 1996-05-29 Tassano ad attivita' antitumorale.
JPH09511212A (ja) * 1993-06-11 1997-11-11 ジ・アップジョン・カンパニー Δ▲上６▼，▲上７▼−タキソール類の抗悪性腫瘍的使用およびそれらを含む医薬組成物
US5405972A (en) * 1993-07-20 1995-04-11 Florida State University Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
US6005120A (en) 1993-07-20 1999-12-21 Florida State University Tricyclic and tetracyclic taxanes
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs
US5767304A (en) * 1996-05-21 1998-06-16 The Scripps Research Institute Catalytic asymmetric aminohydroxylation of olefins with carbamates
CA2288306A1 (en) 1997-04-28 1998-11-05 Rhone-Poulenc Rorer S.A. Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors
US6025516A (en) * 1998-10-14 2000-02-15 Chiragene, Inc. Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes
FR2794771B1 (fr) 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
WO2006055837A2 (en) 2004-11-19 2006-05-26 Dr. Reddy's Laboratories Ltd. Process for preparing oxazolidine derivatives
EP2753355B1 (en) 2011-09-08 2018-10-24 New York University Oncolytic herpes simplex virus and therapeutic uses thereof
WO2013096455A1 (en) 2011-12-20 2013-06-27 Dana-Farber Cancer Institute, Inc. Methods for diagnosing and treating oncogenic kras-associated cancer
EP2855698A4 (en) 2012-05-24 2016-03-30 Dana Farber Cancer Inst Inc TARGETING THE PATHWAY FROM GLUTAMINE TO PYRUVATE TO TREAT CANCER ASSOCIATED WITH ONCOGEN KRAS
US20150285802A1 (en) 2012-07-18 2015-10-08 Dana-Farber Cancer Institute, Inc. Methods for treating, preventing and predicting risk of developing breast cancer
WO2014149871A1 (en) 2013-03-14 2014-09-25 Icahn School Of Medicine At Mount Sinai Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer
WO2015050844A1 (en) 2013-10-01 2015-04-09 Dana-Farber Cancer Institute, Inc. Methods of treating cancer with atovaquone-related compounds
WO2015149006A2 (en) 2014-03-27 2015-10-01 Dana-Farber Cancer Institute, Inc. Compositions and methods for modulating ncoa4-mediated autophagic targeting of ferritin
MA39818A (fr) 2014-03-30 2017-02-08 Benevir Biopharm Inc Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques
EP3307330B1 (en) 2015-06-15 2021-03-10 New York University Method of treatment using oncolytic viruses
CN106748856A (zh) * 2016-12-15 2017-05-31 河南豫辰药业股份有限公司 一种马尿酸乌洛托品中间体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3019069A1 (de) * 1979-05-24 1980-12-04 Lepetit Spa Verfahren zur herstellung eines serinderivats
JPS5829749A (ja) * 1981-08-14 1983-02-22 Hiroyuki Nohira （±）−フエニルグリシノ−ルの光学分割法
CA1228075A (en) * 1983-08-01 1987-10-13 Ryuichi Mita PROCESS FOR PRODUCTION OF .beta.-PHENYLSERINE
JPS60132935A (ja) * 1983-12-20 1985-07-16 Sumitomo Chem Co Ltd フエニルセリン誘導体及びその製造方法
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
IT1211805B (it) * 1987-09-25 1989-11-03 Sefind Srl Dispositivo agevolatore di carico a funzionamento automatico per stive di aeromobili
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol

Also Published As

Publication number Publication date
US5292921A (en) 1994-03-08
HUT62259A (en) 1993-04-28
NO179943B (no) 1996-10-07
CZ280087B6 (cs) 1995-10-18
WO1991017976A1 (fr) 1991-11-28
HU9203650D0 (en) 1993-03-29
JPH05506446A (ja) 1993-09-22
EP0530285B1 (fr) 1994-08-10
NO924489D0 (no) 1992-11-20
IE911738A1 (en) 1991-12-04
AU7972291A (en) 1991-12-10
SK277926B6 (en) 1995-08-09
ATE109768T1 (de) 1994-08-15
ZA913827B (en) 1992-02-26
NZ238207A (en) 1993-07-27
PT97746B (pt) 1998-10-30
AU647490B2 (en) 1994-03-24
DK0530285T3 (da) 1994-09-26
YU89791A (sh) 1994-01-20
IE64687B1 (en) 1995-08-23
FR2662441A1 (fr) 1991-11-29
EP0530285A1 (fr) 1993-03-10
DE69103413D1 (de) 1994-09-15
DE69103413T2 (de) 1994-12-22
RU2086538C1 (ru) 1997-08-10
NO179943C (no) 1997-01-15
ES2057898T3 (es) 1994-10-16
HU210187B (en) 1995-02-28
FI924569A0 (fi) 1992-10-09
CA2079314A1 (fr) 1991-11-23
FR2662441B1 (fr) 1992-10-23
FI924569A (fi) 1992-10-09
NO924489L (no) 1992-11-20
IL98191A0 (en) 1992-06-21
CS9101452A2 (en) 1991-12-17
PT97746A (pt) 1992-02-28

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