IL98176A0 - Bicyclic 1-aza-cycloalkanes,their preparation and pharmaceutical compositions containing them - Google Patents
Bicyclic 1-aza-cycloalkanes,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL98176A0 IL98176A0 IL98176A IL9817691A IL98176A0 IL 98176 A0 IL98176 A0 IL 98176A0 IL 98176 A IL98176 A IL 98176A IL 9817691 A IL9817691 A IL 9817691A IL 98176 A0 IL98176 A0 IL 98176A0
- Authority
- IL
- Israel
- Prior art keywords
- cycloalkanes
- aza
- bicyclic
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4016212 | 1990-05-19 | ||
| DE4018886 | 1990-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL98176A0 true IL98176A0 (en) | 1992-06-21 |
Family
ID=25893382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL98176A IL98176A0 (en) | 1990-05-19 | 1991-05-17 | Bicyclic 1-aza-cycloalkanes,their preparation and pharmaceutical compositions containing them |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0458214A1 (pt) |
| JP (1) | JP2853837B2 (pt) |
| KR (1) | KR910020009A (pt) |
| AU (1) | AU648789B2 (pt) |
| CA (1) | CA2042860A1 (pt) |
| CZ (1) | CZ281837B6 (pt) |
| FI (1) | FI912409A (pt) |
| HU (1) | HUT58091A (pt) |
| IE (1) | IE911688A1 (pt) |
| IL (1) | IL98176A0 (pt) |
| NO (1) | NO911934L (pt) |
| PT (1) | PT97703A (pt) |
| SK (1) | SK279168B6 (pt) |
| YU (1) | YU84791A (pt) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69102816T2 (de) * | 1990-05-11 | 1995-03-16 | Sankyo Co | Piperdinyloxy- und Chinindidinyloxy- isoxazol- Derivate, ihre Herstellung und ihre therapeutische Verwendung. |
| GB9122988D0 (en) * | 1991-10-30 | 1991-12-18 | Ici Plc | Heterocyclic compounds |
| GB9127279D0 (en) * | 1991-12-23 | 1992-02-19 | Ici Plc | Heterocyclic derivatives |
| WO1993021184A1 (en) * | 1992-04-10 | 1993-10-28 | Zeneca Limited | Biphenylylquinuclidine derivatives as squalene synthase inhibitors |
| GB9211796D0 (en) * | 1992-06-04 | 1992-07-15 | Ici Plc | Heterocyclic derivatives |
| IT1255179B (it) * | 1992-06-26 | 1995-10-20 | Enzo Cereda | Azaciclo e azabiciclo alchiliden idrossilamine |
| GB9216721D0 (en) * | 1992-08-06 | 1992-09-23 | Ici Plc | Therapeutic heterocyclic derivatives |
| GB9218334D0 (en) * | 1992-08-28 | 1992-10-14 | Ici Plc | Heterocyclic compounds |
| IL107184A (en) * | 1992-10-09 | 1997-08-14 | Abbott Lab | Heterocyclic ether compounds that enhance cognitive function |
| DE4236331A1 (de) * | 1992-10-28 | 1994-05-05 | Boehringer Ingelheim Kg | Synergistische Kombination |
| GB9226573D0 (en) * | 1992-12-21 | 1993-02-17 | Ici Plc | Heterocyclic compounds |
| IL109451A0 (en) * | 1993-04-29 | 1994-07-31 | Zeneca Ltd | Heterocyclic derivatives |
| US5998404A (en) * | 1994-10-24 | 1999-12-07 | Eli Lilly And Company | Heterocyclic compounds and their use |
| US5512574A (en) * | 1994-12-21 | 1996-04-30 | American Home Products Corporation | Quinuclidine and azabicyclo 2.2.1! heptane pyrazinyl ethers as muscarinic agonists |
| US5859004A (en) * | 1995-02-17 | 1999-01-12 | Novo Nordisk A/S | Use of heterocyclic compounds for the treatment of conditions caused by malfunctioning of the nicotinic cholinergic system |
| US6040442A (en) * | 1995-06-01 | 2000-03-21 | Eli Lilly And Company | Process for preparing 1,2,5-thiadiazole containing ethers |
| US5998434A (en) * | 1995-12-06 | 1999-12-07 | Eli Lilly And Company | Composition for treating pain |
| AU2738397A (en) * | 1996-04-23 | 1997-11-12 | Eli Lilly And Company | Heterocyclic compounds |
| US20050245567A1 (en) * | 2002-08-14 | 2005-11-03 | Dan Peters | Novel quinuclidine derivatives and their use |
| GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
| ATE496050T1 (de) | 2003-08-13 | 2011-02-15 | Neurosearch As | Neue chinuklidinderivative und deren pharmazeutische verwendung |
| US7160876B2 (en) | 2003-12-22 | 2007-01-09 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
| EP1824848A1 (en) * | 2004-12-10 | 2007-08-29 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
| US7655657B2 (en) | 2003-12-22 | 2010-02-02 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
| US20050137203A1 (en) * | 2003-12-22 | 2005-06-23 | Jianguo Ji | 3-quinuclidinyl amino-substituted biaryl derivatives |
| AR049401A1 (es) | 2004-06-18 | 2006-07-26 | Novartis Ag | Aza-biciclononanos |
| GB0415746D0 (en) | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
| GB0521508D0 (en) | 2005-10-21 | 2005-11-30 | Novartis Ag | Organic compounds |
| GB0525673D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| GB0525672D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| TWI775313B (zh) | 2020-02-18 | 2022-08-21 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| JP7429799B2 (ja) | 2020-02-18 | 2024-02-08 | ギリアード サイエンシーズ， インコーポレイテッド | 抗ウイルス化合物 |
| TW202322824A (zh) | 2020-02-18 | 2023-06-16 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| EP4323362A1 (en) | 2021-04-16 | 2024-02-21 | Gilead Sciences, Inc. | Methods of preparing carbanucleosides using amides |
| US12116380B2 (en) | 2021-08-18 | 2024-10-15 | Gilead Sciences, Inc. | Phospholipid compounds and methods of making and using the same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE321933B (pt) * | 1967-10-05 | 1970-03-23 | Astra Ab | |
| FR2014831A1 (en) * | 1968-08-01 | 1970-04-24 | Sogeras | Quinuclidinyl and quinuclidinylalkyl ethers with cholino - lytic, antihistaminic and neurosedative activity |
| GB8615785D0 (en) * | 1986-06-27 | 1986-08-06 | Beecham Group Plc | Compounds |
| AU614513B2 (en) * | 1987-04-15 | 1991-09-05 | Beecham Group Plc | 1-azabicyclic compounds |
| CA1307790C (en) * | 1987-08-04 | 1992-09-22 | Ian Anthony Cliffe | Ethers |
| GB8718445D0 (en) * | 1987-08-04 | 1987-09-09 | Wyeth John & Brother Ltd | Pyridyl-ethers |
| DE3839385A1 (de) * | 1988-11-22 | 1990-05-23 | Boehringer Ingelheim Kg | Neue quinuclidine, ihre herstellung als arzneimittel und verfahren zu ihrer herstellung |
-
1991
- 1991-05-15 YU YU84791A patent/YU84791A/sh unknown
- 1991-05-16 SK SK1448-91A patent/SK279168B6/sk unknown
- 1991-05-16 NO NO91911934A patent/NO911934L/no unknown
- 1991-05-16 CZ CS911448A patent/CZ281837B6/cs not_active IP Right Cessation
- 1991-05-17 PT PT97703A patent/PT97703A/pt not_active Application Discontinuation
- 1991-05-17 JP JP3113418A patent/JP2853837B2/ja not_active Expired - Lifetime
- 1991-05-17 HU HU911663A patent/HUT58091A/hu unknown
- 1991-05-17 EP EP91108054A patent/EP0458214A1/de not_active Ceased
- 1991-05-17 CA CA002042860A patent/CA2042860A1/en not_active Abandoned
- 1991-05-17 FI FI912409A patent/FI912409A/fi not_active Application Discontinuation
- 1991-05-17 IL IL98176A patent/IL98176A0/xx unknown
- 1991-05-17 IE IE168891A patent/IE911688A1/en unknown
- 1991-05-18 KR KR1019910008106A patent/KR910020009A/ko not_active Application Discontinuation
- 1991-05-20 AU AU77130/91A patent/AU648789B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| PT97703A (pt) | 1992-02-28 |
| SK279168B6 (sk) | 1998-07-08 |
| NO911934L (no) | 1991-11-20 |
| HU911663D0 (en) | 1991-11-28 |
| AU7713091A (en) | 1991-11-21 |
| YU84791A (sh) | 1994-06-10 |
| AU648789B2 (en) | 1994-05-05 |
| NO911934D0 (no) | 1991-05-16 |
| FI912409A0 (fi) | 1991-05-17 |
| JP2853837B2 (ja) | 1999-02-03 |
| HUT58091A (en) | 1992-01-28 |
| CS144891A3 (en) | 1992-05-13 |
| IE911688A1 (en) | 1991-11-20 |
| JPH04226981A (ja) | 1992-08-17 |
| EP0458214A1 (de) | 1991-11-27 |
| CZ281837B6 (cs) | 1997-02-12 |
| KR910020009A (ko) | 1991-12-19 |
| CA2042860A1 (en) | 1991-11-20 |
| FI912409A (fi) | 1991-11-20 |
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