IL97993A0 - Polypeptides - Google Patents

Polypeptides

Info

Publication number
IL97993A0
IL97993A0 IL97993A IL9799391A IL97993A0 IL 97993 A0 IL97993 A0 IL 97993A0 IL 97993 A IL97993 A IL 97993A IL 9799391 A IL9799391 A IL 9799391A IL 97993 A0 IL97993 A0 IL 97993A0
Authority
IL
Israel
Prior art keywords
csf
ser
residue
derivatives
naturally occurring
Prior art date
Application number
IL97993A
Other languages
English (en)
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909009623A external-priority patent/GB9009623D0/en
Priority claimed from GB909013773A external-priority patent/GB9013773D0/en
Priority claimed from GB909016215A external-priority patent/GB9016215D0/en
Priority claimed from GB919102799A external-priority patent/GB9102799D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of IL97993A0 publication Critical patent/IL97993A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/145—Colony stimulating factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL97993A 1990-04-30 1991-04-29 Polypeptides IL97993A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB909009623A GB9009623D0 (en) 1990-04-30 1990-04-30 Polypeptides
GB909013773A GB9013773D0 (en) 1990-06-20 1990-06-20 Polypeptides
GB909016215A GB9016215D0 (en) 1990-07-24 1990-07-24 Polypeptides
GB919102799A GB9102799D0 (en) 1991-02-11 1991-02-11 Polypeptides

Publications (1)

Publication Number Publication Date
IL97993A0 true IL97993A0 (en) 1992-06-21

Family

ID=27450502

Family Applications (1)

Application Number Title Priority Date Filing Date
IL97993A IL97993A0 (en) 1990-04-30 1991-04-29 Polypeptides

Country Status (23)

Country Link
US (1) US5416195A (enExample)
EP (1) EP0459630B1 (enExample)
JP (1) JPH06100593A (enExample)
KR (1) KR910018406A (enExample)
AT (1) ATE169336T1 (enExample)
AU (1) AU644647B2 (enExample)
BG (1) BG94328A (enExample)
CA (1) CA2041454A1 (enExample)
CS (1) CS125091A3 (enExample)
DE (1) DE69129927T2 (enExample)
DK (1) DK0459630T3 (enExample)
ES (1) ES2118737T3 (enExample)
FI (1) FI912086A7 (enExample)
GB (1) GB9107846D0 (enExample)
GR (1) GR3027590T3 (enExample)
HU (1) HUT60769A (enExample)
IE (1) IE911440A1 (enExample)
IL (1) IL97993A0 (enExample)
NO (1) NO911696L (enExample)
NZ (1) NZ237974A (enExample)
PT (1) PT97529A (enExample)
TW (1) TW226022B (enExample)
ZW (1) ZW4891A1 (enExample)

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US5581476A (en) * 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
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US20030053982A1 (en) 1994-09-26 2003-03-20 Kinstler Olaf B. N-terminally chemically modified protein compositions and methods
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US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
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US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
US7208473B2 (en) 1999-01-06 2007-04-24 Xencor, Inc. Nucleic acids and protein variants of hG-CSF with granulopoietic activity
AU770131B2 (en) * 1999-01-06 2004-02-12 Xencor, Inc. Nucleic acids and proteins corresponding to mutants of G-CSF with granulopoietic activity
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US6646110B2 (en) * 2000-01-10 2003-11-11 Maxygen Holdings Ltd. G-CSF polypeptides and conjugates
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US8969532B2 (en) 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
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US8758761B2 (en) 2007-09-30 2014-06-24 University Of Florida Research Foundation, Inc. Combination therapies for treating type 1 diabetes
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US20130189239A1 (en) 2008-02-27 2013-07-25 Novo Nordisk A/S Conjugated Factor VIII Molecules
WO2009139784A1 (en) * 2008-05-13 2009-11-19 Nora Therapeutics, Inc. Human g-csf analogs and methods of making and using thereof
EP2323688B1 (en) 2008-07-22 2018-10-17 MenoGeniX, Inc. Compositions and methods for treating symptoms associated with menopause, hormonal variations and arthritis
EP2318029B1 (en) 2008-07-23 2017-11-01 Ambrx, Inc. Modified bovine g-csf polypeptides and their uses
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EP2396023A2 (en) 2009-02-11 2011-12-21 Yeda Research and Development Co. Ltd. Short beta-defensin-derived peptides
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PT2525787T (pt) 2010-01-19 2017-12-18 Hanmi Science Co Ltd Formulações líquidas para conjugado de g-csf de longa ação
MX2012010148A (es) 2010-03-04 2013-01-22 Pfenex Inc Metodo para producir proteinas de interferon recombinantes solubles sin desnaturalizacion.
PL2552949T3 (pl) 2010-04-01 2017-01-31 Pfenex Inc. Sposoby wytwarzania G-CSF w komórce gospodarza Pseudomonas
TWI480288B (zh) 2010-09-23 2015-04-11 Lilly Co Eli 牛顆粒細胞群落刺激因子及其變體之調配物
CN102796197B (zh) * 2011-05-24 2013-12-25 杭州九源基因工程有限公司 一种hsa-gcsf突变体及其制备方法
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Family Cites Families (13)

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US4810643A (en) * 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
DK203187A (da) * 1986-04-22 1987-10-23 Immunex Corp Human g-csf proteinekspression
NO176799C (no) * 1986-12-23 1995-05-31 Kyowa Hakko Kogyo Kk DNA som koder for et polypeptid, rekombinant plasmid som koder for og kan uttrykke et polypeptid og fremgangsmåte for fremstilling av dette polypeptid
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Also Published As

Publication number Publication date
DE69129927D1 (de) 1998-09-10
AU7628491A (en) 1991-11-14
KR910018406A (ko) 1991-11-30
EP0459630A3 (en) 1992-10-21
NO911696L (no) 1991-10-31
PT97529A (pt) 1992-01-31
EP0459630B1 (en) 1998-08-05
JPH06100593A (ja) 1994-04-12
TW226022B (enExample) 1994-07-01
CA2041454A1 (en) 1991-10-31
ES2118737T3 (es) 1998-10-01
HUT60769A (en) 1992-10-28
US5416195A (en) 1995-05-16
ZW4891A1 (en) 1992-01-01
AU644647B2 (en) 1993-12-16
FI912086L (fi) 1991-10-31
BG94328A (bg) 1993-12-24
NO911696D0 (no) 1991-04-29
ATE169336T1 (de) 1998-08-15
NZ237974A (en) 1993-09-27
HU911440D0 (en) 1991-11-28
GR3027590T3 (en) 1998-11-30
DE69129927T2 (de) 1999-04-01
DK0459630T3 (da) 1999-05-03
EP0459630A2 (en) 1991-12-04
FI912086A7 (fi) 1991-10-31
GB9107846D0 (en) 1991-05-29
IE911440A1 (en) 1991-11-06
CS125091A3 (en) 1992-02-19
FI912086A0 (fi) 1991-04-30

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