IL97981A - Method for lowering pollution is transmitted in the amplification process - Google Patents

Method for lowering pollution is transmitted in the amplification process

Info

Publication number
IL97981A
IL97981A IL9798191A IL9798191A IL97981A IL 97981 A IL97981 A IL 97981A IL 9798191 A IL9798191 A IL 9798191A IL 9798191 A IL9798191 A IL 9798191A IL 97981 A IL97981 A IL 97981A
Authority
IL
Israel
Prior art keywords
amplification
modified
amplification product
product
kit
Prior art date
Application number
IL9798191A
Other languages
English (en)
Hebrew (he)
Other versions
IL97981A0 (en
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27059197&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL97981(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of IL97981A0 publication Critical patent/IL97981A0/xx
Publication of IL97981A publication Critical patent/IL97981A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6862—Ligase chain reaction [LCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Amplifiers (AREA)
  • Microwave Amplifiers (AREA)
IL9798191A 1990-05-01 1991-04-28 Method for lowering pollution is transmitted in the amplification process IL97981A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51763190A 1990-05-01 1990-05-01
US68647891A 1991-04-19 1991-04-19

Publications (2)

Publication Number Publication Date
IL97981A0 IL97981A0 (en) 1992-06-21
IL97981A true IL97981A (en) 1996-06-18

Family

ID=27059197

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9798191A IL97981A (en) 1990-05-01 1991-04-28 Method for lowering pollution is transmitted in the amplification process

Country Status (15)

Country Link
US (3) US5427929A (pt)
EP (1) EP0481069A4 (pt)
JP (2) JPH04506906A (pt)
KR (1) KR920702726A (pt)
CN (1) CN1059562A (pt)
BR (1) BR9105737A (pt)
CA (1) CA2063432A1 (pt)
FI (1) FI98932C (pt)
HU (1) HU218095B (pt)
IE (1) IE911456A1 (pt)
IL (1) IL97981A (pt)
NO (1) NO305962B1 (pt)
NZ (1) NZ237996A (pt)
PT (1) PT97534B (pt)
WO (1) WO1991017270A1 (pt)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683896A (en) 1989-06-01 1997-11-04 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
US5035996A (en) * 1989-06-01 1991-07-30 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
US5516663A (en) * 1990-01-26 1996-05-14 Abbott Laboratories Ligase chain reaction with endonuclease IV correction and contamination control
US5516292A (en) * 1991-05-02 1996-05-14 The Research Foundation Of State University Of New York Primer directed nucleic acid amplification including the addition of specific template DNA inactivating enzyme
US6207368B1 (en) 1992-08-04 2001-03-27 Beckman Coulter, Inc. Methods and reagents for controlling chain extension and ligation chain reactions
US6180338B1 (en) 1992-08-04 2001-01-30 Beckman Coulter, Inc. Method, reagent and kit for the detection and amplification of nucleic acid sequences
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US5591575A (en) * 1993-04-07 1997-01-07 Amersham International Plc Subtraction hybridization employing aziridinylbenoquinone cross-linking agents
US5462854A (en) * 1993-04-19 1995-10-31 Beckman Instruments, Inc. Inverse linkage oligonucleotides for chemical and enzymatic processes
US5605796A (en) * 1994-07-19 1997-02-25 Behringwerke Ag Method for preventing amplification of nucleic acid contaminants in amplification mixtures using nuclease-receptor conjugates
ZA956776B (en) 1994-08-25 1996-03-20 Akzo Nobel Nv A process for making the product of a nucleic acid amplification reaction incapable of being a target for further amplification a diagnostic assay employing said process a kit and a container suitable for carrying out said process for assay
US5843650A (en) * 1995-05-01 1998-12-01 Segev; David Nucleic acid detection and amplification by chemical linkage of oligonucleotides
US5830655A (en) * 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US5932450A (en) * 1995-06-07 1999-08-03 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using digestible templates
US5916777A (en) * 1995-06-07 1999-06-29 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
JPH11506605A (ja) * 1995-06-07 1999-06-15 アボツト・ラボラトリーズ 増幅反応におけるバックグラウンドを減少させるためにプローブをマスキングする方法
SE504798C2 (sv) * 1995-06-16 1997-04-28 Ulf Landegren Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten
EP0954612A2 (en) * 1996-11-06 1999-11-10 Sequenom, Inc. Dna diagnostics based on mass spectrometry
JP2001524808A (ja) * 1996-12-10 2001-12-04 ジーントレイス・システムズ・インコーポレイテッド 放出可能な不揮発性の質量標識分子
IL121312A (en) * 1997-07-14 2001-09-13 Technion Res & Dev Foundation Microelectronic components, their manufacture and electronic networks containing them
US6818404B2 (en) 1997-10-23 2004-11-16 Exact Sciences Corporation Methods for detecting hypermethylated nucleic acid in heterogeneous biological samples
CA2307177C (en) 1997-10-23 2004-06-29 Exact Laboratories, Inc. Methods for detecting contamination in molecular diagnostics using pcr
US6437099B1 (en) * 1998-01-07 2002-08-20 Hamamatsu Photonics K.K. Fluorescene—activating antisera and IgG fraction therefrom
US6019839A (en) * 1998-04-17 2000-02-01 Applied Materials, Inc. Method and apparatus for forming an epitaxial titanium silicide film by low pressure chemical vapor deposition
US20030203394A1 (en) * 1998-05-04 2003-10-30 Yoav Eichen Detection of a target in a sample
DE69931928T2 (de) 1998-07-31 2007-01-04 Gen-Probe Inc., San Diego Reversibel inhibierende sonden
IL126776A (en) 1998-10-27 2001-04-30 Technion Res & Dev Foundation A method of investing gold
CA2367405A1 (en) * 1999-04-07 2000-10-12 Dennis Michael Connolly High resolution dna detection methods and devices
US6232104B1 (en) 1999-08-17 2001-05-15 Dade Behring Inc. Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration
US6383755B1 (en) * 1999-09-08 2002-05-07 Clontech Laboratories, Inc. Methods and kits for determining the fidelity of polymerase chain reaction conditions
JP3929775B2 (ja) 1999-09-13 2007-06-13 ニューゲン テクノロジーズ， インコーポレイテッド ポリヌクレオチド配列の線形等温増幅のための方法および組成物
US6692918B2 (en) * 1999-09-13 2004-02-17 Nugen Technologies, Inc. Methods and compositions for linear isothermal amplification of polynucleotide sequences
US7364920B2 (en) * 1999-10-27 2008-04-29 Technion Research And Development Foundation Ltd. Method for gold deposition
EP1152058A1 (en) * 2000-05-03 2001-11-07 Institut Curie Methods and compositions for effecting homologous recombination
AU2001268468A1 (en) 2000-06-13 2001-12-24 The Trustees Of Boston University Use of nucleotide analogs in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing
US7846733B2 (en) * 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
EP1356094B1 (en) * 2000-06-26 2010-01-13 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
CA2389310A1 (en) * 2000-08-30 2002-03-07 Sanko Junyaku Co., Ltd. Method of detecting gene
EP1356104A2 (en) 2000-10-06 2003-10-29 Nugen Technologies, Inc. Methods and probes for detection and/or quantification of nucleic acid sequences
EP1427847B1 (en) 2000-12-13 2010-07-28 Nugen Technologies, Inc. Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
IL153504A0 (en) 2001-03-09 2003-07-06 Nugen Technologies Inc Methods and compositions for amplification of rna sequences
WO2002072773A2 (en) * 2001-03-09 2002-09-19 Nugen Technologies, Inc. Methods and compositions for amplification of rna sequences
US20030203384A1 (en) * 2002-03-08 2003-10-30 Chafin David R. Multiplex detection of biological materials in a sample
ATE405676T1 (de) * 2002-03-11 2008-09-15 Nugen Technologies Inc Verfahren zur erzeugung doppelsträngiger dna mit einem 3'-einzelstranganteil und verwendungen dieser komplexe zur rekombination
CA2486283A1 (en) * 2002-05-17 2004-02-05 Nugen Technologies, Inc. Methods for fragmentation, labeling and immobilization of nucleic acids
WO2004083443A1 (en) 2002-12-20 2004-09-30 Caliper Life Sciences, Inc. Single molecule amplification and detection of dna
CA2521084A1 (en) * 2003-04-14 2004-10-28 Nugen Technologies, Inc. Global amplification using a randomly primed composite primer
WO2005065321A2 (en) 2003-12-29 2005-07-21 Nugen Technologies, Inc. Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids
US20080311627A1 (en) * 2004-06-17 2008-12-18 Epigenomics Ag Compositions and Methods for Preventing Carry-Over Contamination in Nucleic Acid Amplification Reactions
EP1929046B1 (en) 2005-09-07 2012-07-11 Nugen Technologies, Inc. Improved nucleic acid amplification procedure
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US7833716B2 (en) 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
EP2038429B1 (en) * 2006-06-30 2013-08-21 Nugen Technologies, Inc. Methods for fragmentation and labeling of nucleic acids
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US9388457B2 (en) * 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
US20090203531A1 (en) * 2008-02-12 2009-08-13 Nurith Kurn Method for Archiving and Clonal Expansion
WO2009117698A2 (en) 2008-03-21 2009-09-24 Nugen Technologies, Inc. Methods of rna amplification in the presence of dna
CA3155334A1 (en) 2010-10-22 2012-04-26 T2 Biosystems, Inc. NMR SYSTEMS AND METHODS FOR RAPID ANALYTE DETECTION
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
CN102827828B (zh) * 2011-06-16 2014-06-11 华东医学生物技术研究所 一种基于IIs型限制性内切酶消除PCR扩增产物污染的方法
CN104080958A (zh) 2011-10-19 2014-10-01 纽亘技术公司 用于定向核酸扩增和测序的组合物和方法
CN104093890B (zh) 2012-01-26 2016-04-20 纽亘技术公司 用于靶向核酸序列富集和高效文库产生的组合物和方法
JP6181751B2 (ja) 2012-06-18 2017-08-16 ニューゲン テクノロジーズ， インコーポレイテッド 望まれない核酸配列のネガティブ選択のための組成物および方法
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
US20140274738A1 (en) 2013-03-15 2014-09-18 Nugen Technologies, Inc. Sequential sequencing
JP6525473B2 (ja) 2013-11-13 2019-06-05 ニューゲン テクノロジーズ， インコーポレイテッド 複製物配列決定リードを同定するための組成物および方法
WO2015131107A1 (en) 2014-02-28 2015-09-03 Nugen Technologies, Inc. Reduced representation bisulfite sequencing with diversity adaptors
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
CN112301102B (zh) * 2019-07-31 2024-06-25 华南师范大学 一种高特异性的环介导等温扩增方法及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4876187A (en) * 1985-12-05 1989-10-24 Meiogenics, Inc. Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences
AU622426B2 (en) * 1987-12-11 1992-04-09 Abbott Laboratories Assay using template-dependent nucleic acid probe reorganization
EP0451141B1 (en) * 1988-05-20 1998-11-18 F. Hoffmann-La Roche Ag Immobilized sequence-specific probes
US5035996A (en) * 1989-06-01 1991-07-30 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
FR2649122B1 (fr) * 1989-07-03 1991-10-18 Pasteur Institut Perfectionnements apportes aux techniques d'amplification par reaction de polymerisation en chaine (pcr)
DE69024286T2 (de) * 1989-09-01 1996-05-30 Life Technologies Inc Verfahren zur Überprüfung der Kontamination von oligonukleotidabhängigen Nukleinsäure-Amplifikationsreaktionen
EP0497921B1 (en) * 1989-10-26 1999-05-19 ISAACS, Stephen T. Method for inhibiting enzymatic synthesis of nucleic acids using isopsoralens
WO1992018521A1 (en) * 1991-04-10 1992-10-29 Life Technologies, Inc. Method for amplifying and altering an rna sequence

Also Published As

Publication number Publication date
NZ237996A (en) 1993-11-25
NO915136D0 (no) 1991-12-30
PT97534A (pt) 1993-09-30
CA2063432A1 (en) 1991-11-02
KR920702726A (ko) 1992-10-06
US6037152A (en) 2000-03-14
US5427929A (en) 1995-06-27
BR9105737A (pt) 1992-08-18
JPH04506906A (ja) 1992-12-03
IL97981A0 (en) 1992-06-21
EP0481069A4 (en) 1992-06-24
AU7987191A (en) 1991-11-27
IE911456A1 (en) 1991-11-06
HU9200301D0 (en) 1992-04-28
FI916171A0 (fi) 1991-12-31
NO305962B1 (no) 1999-08-23
FI98932C (fi) 1997-09-10
CN1059562A (zh) 1992-03-18
NO915136L (no) 1992-02-28
FI98932B (fi) 1997-05-30
HUT60331A (en) 1992-08-28
EP0481069A1 (en) 1992-04-22
US5876976A (en) 1999-03-02
WO1991017270A1 (en) 1991-11-14
JP2000125890A (ja) 2000-05-09
AU636499B2 (en) 1993-04-29
PT97534B (pt) 1998-11-30
HU218095B (hu) 2000-05-28

Similar Documents

Publication Publication Date Title
US6037152A (en) Method for reducing carryover contamination in an amplification procedure
EP0592035B1 (en) Thermostable DNA polymerase composition comprising a temperature sensitive polymerase inhibitor, diagnostic test kits and methods of use
EP0878553B1 (en) Strand displacement amplification of RNA targets
EP0876510B1 (en) Homogeneous amplification and detection of nucleic acids
US5652107A (en) Diagnostic assays and kits for RNA using RNA binary probes and a ribozyme ligase
AU685903B2 (en) Detection of nucleic acid amplification
US5366877A (en) Restriction/ligation labeling for primer initiated multiple copying of DNA ssequences
US5215899A (en) Nucleic acid amplification employing ligatable hairpin probe and transcription
EP0427074A2 (en) Nucleic acid amplification employing transcribable hairpin probe
NO300782B1 (no) Fremgangsmåte for fremstilling av en dobbelt-trådet nukleinsyre og fremgangsmåte nyttig for påvisning av en spesifikk nukleinsyresekvens i en testpröve
US5807674A (en) Diagnostic assays and kits for RNA using RNA binary probes and a protein that is an RNA-directed RNA ligase
JPH0636760B2 (ja) 核酸の増幅法
CA2008096A1 (en) Nucleic acid amplification using single primer
JPH0634759B2 (ja) テンプレート−依存性核酸プロ−ブ再構成を用いたアッセイ
US5569582A (en) Rapid amplification and detection of nucleic acids
US5605796A (en) Method for preventing amplification of nucleic acid contaminants in amplification mixtures using nuclease-receptor conjugates
WO1994003635A1 (en) Rapid amplification and detection of nucleic acids
US6280930B1 (en) Amplifying and detecting target nucleic acids using a post amplification incubation step
US5650302A (en) Method for reducing carryover contamination in an amplification procedure
AU636499C (en) Method for reducing carryover contamination in an amplification procedure
AU768981B2 (en) Amplifying and detecting target nucleic acids using a post amplification incubation step
CA2075083A1 (en) Rapid amplification and detection of nucleic acids

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees