IL96009A0 - Pyrimidines - Google Patents

Pyrimidines

Info

Publication number
IL96009A0
IL96009A0 IL96009A IL9600990A IL96009A0 IL 96009 A0 IL96009 A0 IL 96009A0 IL 96009 A IL96009 A IL 96009A IL 9600990 A IL9600990 A IL 9600990A IL 96009 A0 IL96009 A0 IL 96009A0
Authority
IL
Israel
Prior art keywords
pyrimidines
Prior art date
Application number
IL96009A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL96009A0 publication Critical patent/IL96009A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL96009A 1989-10-19 1990-10-15 Pyrimidines IL96009A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH379989 1989-10-19

Publications (1)

Publication Number Publication Date
IL96009A0 true IL96009A0 (en) 1991-07-18

Family

ID=4263704

Family Applications (1)

Application Number Title Priority Date Filing Date
IL96009A IL96009A0 (en) 1989-10-19 1990-10-15 Pyrimidines

Country Status (14)

Country Link
EP (1) EP0424317A3 (no)
JP (1) JPH03133964A (no)
KR (1) KR910007889A (no)
AU (1) AU638496B2 (no)
CA (1) CA2027839A1 (no)
FI (1) FI93957C (no)
HU (1) HUT55383A (no)
IE (1) IE903749A1 (no)
IL (1) IL96009A0 (no)
MX (1) MX22877A (no)
NO (1) NO176758C (no)
NZ (1) NZ235726A (no)
PT (1) PT95626A (no)
ZA (1) ZA908344B (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05505609A (ja) * 1990-03-30 1993-08-19 メルク・エンド・カムパニー・インコーポレーテツド 置換ピリミジン、ピリミジノンおよびピリドリミジン
US5324729A (en) * 1990-03-30 1994-06-28 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
NZ238624A (en) * 1990-06-19 1994-08-26 Meiji Seika Co Pyridine derivatives, compositions, preparations and use thereof
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
IE912956A1 (en) * 1990-09-10 1992-03-11 Abbott Lab Angiotensin ii receptor antagonists
FR2672892B1 (fr) * 1991-02-20 1994-01-14 Synthelabo Derives de 4-pyrimidinones, leur preparation et leur application en therapeutique.
US5472967A (en) * 1991-02-20 1995-12-05 Synthelabo 4-pyrimidinone derivatives their preparation and their application in therapy
DE4110019C2 (de) * 1991-03-27 2000-04-13 Merck Patent Gmbh Imidazopyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
AU1625192A (en) * 1991-05-31 1992-12-03 Zeneca Limited Heterocyclic derivatives
IT1250749B (it) * 1991-08-02 1995-04-21 Luso Farmaco Inst Composti eterociclici ad attivita' a ii antagonista
US5256781A (en) * 1991-10-24 1993-10-26 American Home Products Corporation Substituted quinazolines as angiotensin II antagonists
US5236925A (en) * 1991-10-24 1993-08-17 American Home Products Corporation Fused pyrimidines as angiotensin II antagonists
US5234936A (en) * 1991-10-24 1993-08-10 American Home Products Corporation Pyrimidocycloalkanes as a ii antagonists
DE4221583A1 (de) 1991-11-12 1993-05-13 Bayer Ag Substituierte biphenylpyridone
GB9125842D0 (en) * 1991-12-04 1992-02-05 Ici Plc Heterocyclic derivatives
US5225408A (en) * 1991-12-20 1993-07-06 E. R. Squibb & Sons, Inc. Biphenyl oxadiazinone angiotensin II inhibitors
IL104756A0 (en) * 1992-02-17 1993-06-10 Ciba Geigy Ag Composition for the treatment of glaucoma
US5378704A (en) * 1992-04-15 1995-01-03 E. R. Squibb & Sons, Inc. Non-peptidic angiotensin-II-receptor-antagonists
US5236916A (en) * 1992-05-26 1993-08-17 E. R. Squibb & Sons, Inc. Oxadiazinone substituted indole and benzimidazole derivatives
TW348175B (en) * 1993-01-06 1998-12-21 Hoechst Ag Process for the preparation of biphenyl derivatives
AU1522400A (en) 1998-11-12 2000-05-29 Elan Pharmaceuticals, Inc. Substituted pyrimidine compositions and methods of use
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
US7691898B2 (en) 2004-10-08 2010-04-06 Kotobuki Pharmaceutical Co., Ltd. Phosphonic acid derivatives and the treating agents of diseases related hyperphosphatemia
DK1869023T3 (da) * 2005-04-12 2012-04-10 Vicore Pharma Ab Nye tricykliske angiotensin-II-agonister
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
JPWO2011105099A1 (ja) * 2010-02-25 2013-06-20 興和株式会社 新規な4−アルコキシピリミジン構造を有する化合物及びこれを含有する医薬
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
PT3004138T (pt) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos
WO2022057858A1 (zh) * 2020-09-17 2022-03-24 浙江海正药业股份有限公司 酰胺膦氧类衍生物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles

Also Published As

Publication number Publication date
PT95626A (pt) 1991-09-13
ZA908344B (en) 1991-06-26
AU638496B2 (en) 1993-07-01
HU906501D0 (en) 1991-04-29
FI905124A0 (fi) 1990-10-17
NO176758C (no) 1995-05-24
KR910007889A (ko) 1991-05-30
EP0424317A2 (de) 1991-04-24
AU6468090A (en) 1991-04-26
FI93957C (fi) 1995-06-26
NO904511D0 (no) 1990-10-18
IE903749A1 (en) 1991-04-24
CA2027839A1 (en) 1991-04-20
NO904511L (no) 1991-04-22
EP0424317A3 (en) 1991-09-25
NO176758B (no) 1995-02-13
NZ235726A (en) 1993-09-27
MX22877A (es) 1993-12-01
FI93957B (fi) 1995-03-15
HUT55383A (en) 1991-05-28
JPH03133964A (ja) 1991-06-07

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