IL96009A0 - Pyrimidines - Google Patents

Pyrimidines

Info

Publication number
IL96009A0
IL96009A0 IL96009A IL9600990A IL96009A0 IL 96009 A0 IL96009 A0 IL 96009A0 IL 96009 A IL96009 A IL 96009A IL 9600990 A IL9600990 A IL 9600990A IL 96009 A0 IL96009 A0 IL 96009A0
Authority
IL
Israel
Prior art keywords
pyrimidines
Prior art date
Application number
IL96009A
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL96009A0 publication Critical patent/IL96009A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL96009A 1989-10-19 1990-10-15 Pyrimidines IL96009A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH379989 1989-10-19

Publications (1)

Publication Number Publication Date
IL96009A0 true IL96009A0 (en) 1991-07-18

Family

ID=4263704

Family Applications (1)

Application Number Title Priority Date Filing Date
IL96009A IL96009A0 (en) 1989-10-19 1990-10-15 Pyrimidines

Country Status (14)

Country Link
EP (1) EP0424317A3 (en)
JP (1) JPH03133964A (en)
KR (1) KR910007889A (en)
AU (1) AU638496B2 (en)
CA (1) CA2027839A1 (en)
FI (1) FI93957C (en)
HU (1) HUT55383A (en)
IE (1) IE903749A1 (en)
IL (1) IL96009A0 (en)
MX (1) MX22877A (en)
NO (1) NO176758C (en)
NZ (1) NZ235726A (en)
PT (1) PT95626A (en)
ZA (1) ZA908344B (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324729A (en) * 1990-03-30 1994-06-28 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
EP0522038A4 (en) * 1990-03-30 1993-05-26 Merck & Co. Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
AU653734B2 (en) * 1990-06-19 1994-10-13 Meiji Seika Kabushiki Kaisha Substituted 4-biphenylmethoxypyridine derivatives
IL99246A0 (en) * 1990-09-10 1992-07-15 Abbott Lab Angiotensin ii receptor antagonists and pharmaceutical compositions containing them
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
FR2672892B1 (en) * 1991-02-20 1994-01-14 Synthelabo DERIVATIVES OF 4-PYRIMIDINONES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
US5472967A (en) * 1991-02-20 1995-12-05 Synthelabo 4-pyrimidinone derivatives their preparation and their application in therapy
DE4110019C2 (en) * 1991-03-27 2000-04-13 Merck Patent Gmbh Imidazopyridines, processes for their production and pharmaceutical preparations containing them
IL101860A0 (en) * 1991-05-31 1992-12-30 Ici Plc Heterocyclic derivatives
IT1250749B (en) * 1991-08-02 1995-04-21 Luso Farmaco Inst HETEROCYCLIC COMPOUNDS ACTIVATED IN II ANTAGONIST
US5256781A (en) * 1991-10-24 1993-10-26 American Home Products Corporation Substituted quinazolines as angiotensin II antagonists
US5236925A (en) * 1991-10-24 1993-08-17 American Home Products Corporation Fused pyrimidines as angiotensin II antagonists
US5234936A (en) * 1991-10-24 1993-08-10 American Home Products Corporation Pyrimidocycloalkanes as a ii antagonists
DE4221583A1 (en) 1991-11-12 1993-05-13 Bayer Ag SUBSTITUTED BIPHENYLPYRIDONE
GB9125842D0 (en) * 1991-12-04 1992-02-05 Ici Plc Heterocyclic derivatives
US5225408A (en) * 1991-12-20 1993-07-06 E. R. Squibb & Sons, Inc. Biphenyl oxadiazinone angiotensin II inhibitors
IL104756A0 (en) * 1992-02-17 1993-06-10 Ciba Geigy Ag Composition for the treatment of glaucoma
US5378704A (en) * 1992-04-15 1995-01-03 E. R. Squibb & Sons, Inc. Non-peptidic angiotensin-II-receptor-antagonists
US5236916A (en) * 1992-05-26 1993-08-17 E. R. Squibb & Sons, Inc. Oxadiazinone substituted indole and benzimidazole derivatives
TW348175B (en) * 1993-01-06 1998-12-21 Hoechst Ag Process for the preparation of biphenyl derivatives
US6518424B1 (en) 1998-11-12 2003-02-11 Elan Pharmaceuticals, Inc. Substituted pyrimidine compositions and methods of use
SE9903028D0 (en) 1999-08-27 1999-08-27 Astra Ab New use
WO2006038719A1 (en) 2004-10-08 2006-04-13 Kotobuki Pharmaceutical Co., Ltd. Phosphonic acid derivative and therapeutic agent for disease in which high phosphate level in blood participates
AU2006235698B2 (en) * 2005-04-12 2012-03-29 Vicore Pharma Ab New tricyclic angiotensin II agonists
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2527360B1 (en) 2007-06-04 2015-10-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (en) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others
WO2011105099A1 (en) * 2010-02-25 2011-09-01 興和株式会社 Compound containing a novel 4-alkoxypyridine formation and medicine containing same
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
US10011637B2 (en) 2013-06-05 2018-07-03 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase C, method of making and using same
CN116134025A (en) * 2020-09-17 2023-05-16 浙江海正药业股份有限公司 Amide phosphine oxide derivative and preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles

Also Published As

Publication number Publication date
NO176758B (en) 1995-02-13
FI93957C (en) 1995-06-26
FI905124A0 (en) 1990-10-17
AU6468090A (en) 1991-04-26
HUT55383A (en) 1991-05-28
ZA908344B (en) 1991-06-26
NO904511D0 (en) 1990-10-18
EP0424317A2 (en) 1991-04-24
FI93957B (en) 1995-03-15
EP0424317A3 (en) 1991-09-25
HU906501D0 (en) 1991-04-29
CA2027839A1 (en) 1991-04-20
NO904511L (en) 1991-04-22
NZ235726A (en) 1993-09-27
MX22877A (en) 1993-12-01
PT95626A (en) 1991-09-13
NO176758C (en) 1995-05-24
AU638496B2 (en) 1993-07-01
KR910007889A (en) 1991-05-30
IE903749A1 (en) 1991-04-24
JPH03133964A (en) 1991-06-07

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