IL94936A - History of acrylic amides, process for their preparation and pharmaceutical mixtures containing them - Google Patents

History of acrylic amides, process for their preparation and pharmaceutical mixtures containing them

Info

Publication number
IL94936A
IL94936A IL9493690A IL9493690A IL94936A IL 94936 A IL94936 A IL 94936A IL 9493690 A IL9493690 A IL 9493690A IL 9493690 A IL9493690 A IL 9493690A IL 94936 A IL94936 A IL 94936A
Authority
IL
Israel
Prior art keywords
pharmaceutically acceptable
group
acceptable salt
propenoyl
phenylsulfonyl
Prior art date
Application number
IL9493690A
Other languages
English (en)
Hebrew (he)
Other versions
IL94936A0 (en
Original Assignee
Richter Gedeon Vegyzeti Gyar R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyzeti Gyar R filed Critical Richter Gedeon Vegyzeti Gyar R
Publication of IL94936A0 publication Critical patent/IL94936A0/xx
Publication of IL94936A publication Critical patent/IL94936A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/54—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
IL9493690A 1989-07-14 1990-06-29 History of acrylic amides, process for their preparation and pharmaceutical mixtures containing them IL94936A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU893571A HU203872B (en) 1989-07-14 1989-07-14 Process for producing amides of acrylic acid and their salts and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
IL94936A0 IL94936A0 (en) 1991-04-15
IL94936A true IL94936A (en) 1995-01-24

Family

ID=10964595

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9493690A IL94936A (en) 1989-07-14 1990-06-29 History of acrylic amides, process for their preparation and pharmaceutical mixtures containing them

Country Status (13)

Country Link
US (1) US5214045A (ja)
EP (1) EP0408106B1 (ja)
JP (1) JPH0352853A (ja)
KR (1) KR910002787A (ja)
CN (1) CN1048703A (ja)
AT (1) ATE103892T1 (ja)
CA (1) CA2021145A1 (ja)
DE (1) DE69007877T2 (ja)
HU (1) HU203872B (ja)
IL (1) IL94936A (ja)
LT (1) LTIP1787A (ja)
LV (1) LV10711A (ja)
RU (1) RU2021259C1 (ja)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2532291A (en) * 1948-10-02 1950-12-05 Rohm & Haas Phenylmercaptoacrylates and phenylmercaptomaleates
GB1528853A (en) * 1975-07-04 1978-10-18 Kao Corp Betathio acrylic acid compounds and process of preparing same
JPS5953900B2 (ja) * 1976-06-07 1984-12-27 花王株式会社 β−スルフエニルアクリル酸及びその誘導体
JPS5953898B2 (ja) * 1976-06-07 1984-12-27 花王株式会社 スルフイニル基またはスルホニル基を有する脂肪族化合物
US4283407A (en) * 1977-09-28 1981-08-11 Science Union Et Cie Thiopropionamides, and the pharmaceutical compositions
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
US4308392A (en) * 1979-12-03 1981-12-29 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of mercaptoacyl amino acids
JPS58140065A (ja) * 1982-02-10 1983-08-19 Meito Sangyo Kk メルカプトベンジル脂肪酸誘導体類及びその製法
AU584668B2 (en) * 1985-02-04 1989-06-01 G.D. Searle & Co. Novel heterocyclic amides useful as anti-inflammatory and anti-allergy agents

Also Published As

Publication number Publication date
HU203872B (en) 1991-10-28
KR910002787A (ko) 1991-02-26
ATE103892T1 (de) 1994-04-15
LTIP1787A (en) 1995-08-25
DE69007877T2 (de) 1994-07-28
JPH0352853A (ja) 1991-03-07
LV10711A (lv) 1995-06-20
EP0408106B1 (en) 1994-04-06
US5214045A (en) 1993-05-25
CN1048703A (zh) 1991-01-23
EP0408106A3 (en) 1991-04-24
EP0408106A2 (en) 1991-01-16
DE69007877D1 (de) 1994-05-11
RU2021259C1 (ru) 1994-10-15
CA2021145A1 (en) 1991-01-15
IL94936A0 (en) 1991-04-15

Similar Documents

Publication Publication Date Title
KR100352316B1 (ko) 메탈로프로테아제억제제로서사용되는술포닐아미노치환히드록삼산유도체
DE69716619T2 (de) Phosphinsäureamide als matrix metalloprotease inhibitoren
US5025001A (en) S-nitroso derivatives of ACE inhibitors and the use thereof
US5356890A (en) S-nitroso derivatives of ace inhibitors and the use thereof
HU211287A9 (en) Hydroxamic acid derivatives as metalloproteinase inhibitors
JPH04503057A (ja) ヒドロキサム酸に基礎を置くコラゲナーゼ阻害剤
JPH01160992A (ja) 新規化合物、その製法及びそれを含む医薬組成物
US4937243A (en) Thiol carboxylic acid derivatives and their use as colagenase inhibitors
US4250183A (en) N-(Substituted amino)alkanoyl-aminoalkanoic acids and salts, their use and their compositions
US5187183A (en) S-nitroso derivatives of ACE inhibitors and the use thereof
IE910745A1 (en) Glycinamide derivatives, their preparation, pharmaceutical¹compositions containing them, and their use
EP0408106B1 (en) Novel acrylic amide derivatives, a process for their preparation, pharmaceutical compositions containing the same and their use in medicine
EP0158947B1 (en) Amino thiol dipeptides
PL167915B1 (pl) Sposób otrzymywania nowych N-( a-podstawionych-pirydynylo)karbonylo-dipeptydów PL PL PL
WO1998023588A9 (en) Metalloproteinase inhibitors
EP0408107B1 (en) Novel acrylic acid salts, a process for their preparation, pharmaceutical compositions containing them and their use in the medicine
EP0309261B1 (en) Butenoic acid amides, their salts, pharmaceutical compositions containing them and process for preparing same
US4146728A (en) Esters of 2-[4-(4-chlorobenzoyl)-phenoxy-2-methyl-propionic acid with bis-(hydroxyalkylthio)-alkanes
EP0408108A2 (en) Pharmaceutical compositions containing acrylic acid derivatives and their use in the medicine
AU1270402A (en) Peptide derivatives and their pharmaceutically acceptable salts, processes for preparation of both, and use thereof
JPH0822847B2 (ja) 縮合ベンゼン誘導体、それを含有する医薬及び該化合物の製造中間体
GB2141713A (en) Carboxylic acid amides and imides, their preparation and pharmaceutical compositions containing them
WO1994014788A1 (en) Novel derivatives of a five-membered ring fused benzene, pharmaceutical compositions containing them and process for preparing same
WO1994014765A1 (en) Cyclohexylsulfonyl-acrylic acid and its derivatives, pharmaceutical compositions containing them and process for preparing same
EP0319644A2 (en) Alkylated amide derivatives, their use and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
RH Patent void