LTIP1787A - Novel acrylic amide derivatives, aprocess for their preparation, pharmaceutical compositions containing the same and their use in medicine - Google Patents

Novel acrylic amide derivatives, aprocess for their preparation, pharmaceutical compositions containing the same and their use in medicine

Info

Publication number
LTIP1787A
LTIP1787A LTIP1787A LTIP1787A LTIP1787A LT IP1787 A LTIP1787 A LT IP1787A LT IP1787 A LTIP1787 A LT IP1787A LT IP1787 A LTIP1787 A LT IP1787A LT IP1787 A LTIP1787 A LT IP1787A
Authority
LT
Lithuania
Prior art keywords
group
preparation
4alkyl
aprocess
medicine
Prior art date
Application number
LTIP1787A
Other languages
English (en)
Inventor
Tamas Fodor
Janos Fischer
Laszlo Dobay
Elemer Ezer
Judit Matuz
Katalin Saghy
Laszlo Szporny
Gyorgy Hajos
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of LTIP1787A publication Critical patent/LTIP1787A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/54Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and unsaturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
LTIP1787A 1989-07-14 1994-01-21 Novel acrylic amide derivatives, aprocess for their preparation, pharmaceutical compositions containing the same and their use in medicine LTIP1787A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU893571A HU203872B (en) 1989-07-14 1989-07-14 Process for producing amides of acrylic acid and their salts and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
LTIP1787A true LTIP1787A (en) 1995-08-25

Family

ID=10964595

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1787A LTIP1787A (en) 1989-07-14 1994-01-21 Novel acrylic amide derivatives, aprocess for their preparation, pharmaceutical compositions containing the same and their use in medicine

Country Status (13)

Country Link
US (1) US5214045A (xx)
EP (1) EP0408106B1 (xx)
JP (1) JPH0352853A (xx)
KR (1) KR910002787A (xx)
CN (1) CN1048703A (xx)
AT (1) ATE103892T1 (xx)
CA (1) CA2021145A1 (xx)
DE (1) DE69007877T2 (xx)
HU (1) HU203872B (xx)
IL (1) IL94936A (xx)
LT (1) LTIP1787A (xx)
LV (1) LV10711A (xx)
RU (1) RU2021259C1 (xx)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2532291A (en) * 1948-10-02 1950-12-05 Rohm & Haas Phenylmercaptoacrylates and phenylmercaptomaleates
GB1528853A (en) * 1975-07-04 1978-10-18 Kao Corp Betathio acrylic acid compounds and process of preparing same
JPS5953898B2 (ja) * 1976-06-07 1984-12-27 花王株式会社 スルフイニル基またはスルホニル基を有する脂肪族化合物
JPS5953900B2 (ja) * 1976-06-07 1984-12-27 花王株式会社 β−スルフエニルアクリル酸及びその誘導体
US4283407A (en) * 1977-09-28 1981-08-11 Science Union Et Cie Thiopropionamides, and the pharmaceutical compositions
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
US4308392A (en) * 1979-12-03 1981-12-29 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of mercaptoacyl amino acids
JPS58140065A (ja) * 1982-02-10 1983-08-19 Meito Sangyo Kk メルカプトベンジル脂肪酸誘導体類及びその製法
AU584668B2 (en) * 1985-02-04 1989-06-01 G.D. Searle & Co. Novel heterocyclic amides useful as anti-inflammatory and anti-allergy agents

Also Published As

Publication number Publication date
IL94936A (en) 1995-01-24
EP0408106A3 (en) 1991-04-24
CA2021145A1 (en) 1991-01-15
DE69007877T2 (de) 1994-07-28
ATE103892T1 (de) 1994-04-15
EP0408106A2 (en) 1991-01-16
LV10711A (lv) 1995-06-20
US5214045A (en) 1993-05-25
CN1048703A (zh) 1991-01-23
JPH0352853A (ja) 1991-03-07
KR910002787A (ko) 1991-02-26
IL94936A0 (en) 1991-04-15
EP0408106B1 (en) 1994-04-06
RU2021259C1 (ru) 1994-10-15
HU203872B (en) 1991-10-28
DE69007877D1 (de) 1994-05-11

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Legal Events

Date Code Title Description
FD9A Withdrawn applications

Free format text: 960109