IL90337A0 - Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents - Google Patents

Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents

Info

Publication number
IL90337A0
IL90337A0 IL90337A IL9033789A IL90337A0 IL 90337 A0 IL90337 A0 IL 90337A0 IL 90337 A IL90337 A IL 90337A IL 9033789 A IL9033789 A IL 9033789A IL 90337 A0 IL90337 A0 IL 90337A0
Authority
IL
Israel
Prior art keywords
aromatic
antineoplastic agents
carboxamide derivatives
heterocyclic carboxamide
heterocyclic
Prior art date
Application number
IL90337A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL90337A0 publication Critical patent/IL90337A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Graft Or Block Polymers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL90337A 1988-05-24 1989-05-18 Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents IL90337A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19803488A 1988-05-24 1988-05-24

Publications (1)

Publication Number Publication Date
IL90337A0 true IL90337A0 (en) 1989-12-15

Family

ID=22731735

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90337A IL90337A0 (en) 1988-05-24 1989-05-18 Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents

Country Status (25)

Country Link
EP (1) EP0343893B1 (pl)
JP (1) JPH0678331B2 (pl)
KR (1) KR910006864B1 (pl)
CN (1) CN1023700C (pl)
AT (1) ATE79114T1 (pl)
AU (1) AU601905B2 (pl)
CA (1) CA1328871C (pl)
DD (1) DD283815A5 (pl)
DE (1) DE68902358T2 (pl)
DK (1) DK249389A (pl)
ES (1) ES2043012T3 (pl)
FI (1) FI892498A7 (pl)
GR (1) GR3005844T3 (pl)
HU (1) HU202507B (pl)
IE (1) IE891667L (pl)
IL (1) IL90337A0 (pl)
MX (1) MX173140B (pl)
MY (1) MY106035A (pl)
NO (1) NO172389C (pl)
NZ (1) NZ229234A (pl)
PL (1) PL154875B1 (pl)
PT (1) PT90622B (pl)
SU (1) SU1681728A3 (pl)
YU (1) YU47019B (pl)
ZA (1) ZA893862B (pl)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2790299B2 (ja) * 1989-02-01 1998-08-27 保土谷化学工業株式会社 ペンゾチアゾール誘導体
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
RU2196769C2 (ru) * 1995-08-30 2003-01-20 Джи. Ди. Сирл Энд Ко. Производные аминобензойной кислоты, фармацевтическая композиция
US6100423A (en) * 1995-08-30 2000-08-08 G. D. Searle & Co. Amino benzenepropanoic acid compounds and derivatives thereof
US5716281A (en) * 1995-11-27 1998-02-10 Sega Enterprises, Ltd. Game apparatus using a vehicle with an optical image synthesizing system
TW513418B (en) * 1996-07-31 2002-12-11 Otsuka Pharma Co Ltd Thiazole derivatives, their production and use
IL135176A0 (en) 1997-11-10 2001-05-20 Bristol Myers Squibb Co Benzothiazole derivatives and pharmaceutical compositions containing the same
SI0928793T1 (en) * 1998-01-02 2002-10-31 F. Hoffmann-La Roche Ag Thiazole derivatives
WO1999052861A1 (de) * 1998-04-09 1999-10-21 Institut für Diagnostikforschung GmbH an der Freien Universität Berlin Neue benzylguanidinderivate für die therapie, in-vivo- und in-vitro-diagnostik
CZ2003182A3 (cs) 2000-06-21 2003-06-18 F. Hoffmann-La Roche Ag Deriváty benzothiazolu
US6599901B1 (en) * 2001-11-19 2003-07-29 Hoffman-La Roche Inc. Pyridone substituted benzothiazole derivatives
US6620811B2 (en) * 2001-11-19 2003-09-16 Hoffmann-La Roche Inc. Isonicotin- and nicotinamide derivatives of benzothiazoles
US6624163B2 (en) * 2001-11-29 2003-09-23 Hoffman-La Roche Inc. Benzothiazole derivatives
GB0130868D0 (en) 2001-12-24 2002-02-06 Univ Strathclyde New compounds
CN100357283C (zh) * 2002-04-02 2007-12-26 中国科学院上海药物研究所 一类甲硫氨酰氨肽酶抑制剂
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
CN100372844C (zh) * 2003-05-13 2008-03-05 弗·哈夫曼-拉罗切有限公司 作为腺苷受体配体的2-咪唑-苯并噻唑
MXPA05012360A (es) * 2003-05-19 2006-02-02 Hoffmann La Roche Derivados de benzotiazol como ligandos receptores de adenosina.
WO2004103367A1 (en) * 2003-05-21 2004-12-02 F. Hoffmann-La Roche Ag Benzothiazole derivatives and use thereof in the treatment of diseases relates to the adenosine a2a receptor
KR100765566B1 (ko) * 2003-05-30 2007-10-09 에프. 호프만-라 로슈 아게 벤조티아졸 유도체 및 아데노신 ａ２ａ 수용체와 관련된질병의 치료에서의 이들의 용도
UA87986C2 (uk) * 2003-07-28 2009-09-10 Янссен Фармацевтика Н.В. Бензімідазольні, бензтіазольні та бензоксазольні похідні і їх застосування як lta4h модуляторів
DE602005004142T2 (de) 2004-05-24 2009-01-02 F. Hoffmann-La Roche Ag 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4-methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid
DE602005019408D1 (de) * 2004-07-22 2010-04-01 Hoffmann La Roche Benzothiazolderivate
CN1989117B (zh) * 2004-07-22 2011-01-19 弗·哈夫曼-拉罗切有限公司 取代的苯并噻唑
ATE400557T1 (de) 2004-11-05 2008-07-15 Hoffmann La Roche Verfahren zur herstellung von isonikotinsäurederivaten
ATE460417T1 (de) 2005-03-23 2010-03-15 Hoffmann La Roche Acetylenylpyrazolopyrimidinderivate als mglur2- antagonsten
ES2340321T3 (es) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2.
EP1994017A2 (en) * 2006-03-15 2008-11-26 4Sc Ag Novel heterocyclic nf-kb inhibitors
GB0619325D0 (en) 2006-09-30 2006-11-08 Univ Strathclyde New compounds
EP2311842A3 (en) * 2008-06-24 2011-07-13 Takeda Pharmaceutical Company Limited PI3K/M TOR inhibitors
US9499790B2 (en) 2010-08-26 2016-11-22 Kyoto University Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells
JP2014528412A (ja) * 2011-09-30 2014-10-27 キネタ・インコーポレイテツド 抗ウイルス化合物
KR101996343B1 (ko) 2012-01-27 2019-07-05 고쿠리츠 다이가쿠 호진 교토 다이가쿠 전능성 줄기세포의 심근분화 유도방법
JP6351567B2 (ja) 2013-03-08 2018-07-04 国立大学法人京都大学 Ｅｇｆ受容体阻害剤を含む多能性幹細胞の心筋分化促進剤
JP6333830B2 (ja) * 2013-09-13 2018-05-30 国立大学法人京都大学 多能性幹細胞の心筋分化を促進する化合物
JP6651218B2 (ja) 2014-05-30 2020-02-19 国立大学法人京都大学 低分子化合物を用いた多能性幹細胞の心筋分化誘導法
CN109776486A (zh) * 2019-02-26 2019-05-21 武汉松石科技股份有限公司 一种硫酸亚丙酯的制备方法
CN110590735B (zh) * 2019-09-30 2021-07-23 江苏国泰超威新材料有限公司 一种环状硫酸酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61225168A (ja) * 1985-03-30 1986-10-06 Nippon Tokushu Noyaku Seizo Kk 新規ベンズアミド、その製法及び殺虫剤
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
GB8611606D0 (en) * 1986-05-13 1986-06-18 Fbc Ltd Fungicides

Also Published As

Publication number Publication date
NO172389B (no) 1993-04-05
DE68902358T2 (de) 1992-12-10
IE891667L (en) 1989-11-24
JPH0678331B2 (ja) 1994-10-05
HUT51606A (en) 1990-05-28
EP0343893B1 (en) 1992-08-05
PT90622B (pt) 1994-10-31
PL154875B1 (en) 1991-09-30
DK249389A (da) 1989-11-27
AU3509889A (en) 1989-11-30
DE68902358D1 (de) 1992-09-10
NO892059L (no) 1989-11-27
NO892059D0 (no) 1989-05-23
HU202507B (en) 1991-03-28
MY106035A (en) 1995-03-31
YU105989A (en) 1990-08-31
JPH0217181A (ja) 1990-01-22
DK249389D0 (da) 1989-05-23
ES2043012T3 (es) 1993-12-16
CN1037898A (zh) 1989-12-13
NO172389C (no) 1993-07-14
PL279613A1 (en) 1989-11-27
AU601905B2 (en) 1990-09-20
YU47019B (sh) 1994-11-15
MX173140B (es) 1994-02-02
KR890017248A (ko) 1989-12-15
NZ229234A (en) 1990-09-26
SU1681728A3 (ru) 1991-09-30
ATE79114T1 (de) 1992-08-15
DD283815A5 (de) 1990-10-24
KR910006864B1 (ko) 1991-09-09
ZA893862B (en) 1991-01-30
CA1328871C (en) 1994-04-26
CN1023700C (zh) 1994-02-09
FI892498A0 (fi) 1989-05-23
EP0343893A1 (en) 1989-11-29
FI892498A7 (fi) 1989-11-25
MX16158A (es) 1993-06-01
GR3005844T3 (pl) 1993-06-07
PT90622A (pt) 1989-11-30

Similar Documents

Publication Publication Date Title
IL90337A0 (en) Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
AR242569A1 (es) Procedimiento para la fabricacion de un derivado de amida de indol, indolina, indazol, bencimidazol, benzotiofeno, benzoxazina, benzotriazol e indazolona.
YU123689A (en) Acyl derivatives
NZ221352A (en) N-phenyl amide derivatives and pharmaceutical compositions
GB8600326D0 (en) Preventing movement of article along shaft/bore
PH25646A (en) Acyl derivatives
YU219789A (en) Acyl derivatives
GB2176185B (en) N-(3 nitroquinolin-4-yl) guarnidine derivatives
IL88342A0 (en) New derivatives of cysteine
NZ215424A (en) Bis(heterocyclically substituted)disulphide derivatives and pharmaceutical agents
ZA884093B (en) Acyl derivatives
CS693488A1 (en) Derivatives of sulphonamides
MW3086A1 (en) Heterocyclic amide derivatives
GB8509882D0 (en) Heterocyclic amide derivatives
GB8525658D0 (en) Heterocyclic amide derivatives
YU54789A (en) Substituted derivatives of thiourea
ZA885790B (en) Acyl derivatives
ZA889425B (en) Acyl derivatives
ZA882389B (en) Acyl derivatives
IE881065L (en) Acyl derivatives of cephalosporins
IE880619L (en) 27-halo derivatives of ll-f28249 n of an¹expendable pattern
IE881760L (en) Derivatives of n-phenylpyrazoles
YU11688A (en) Derivatives of pyridazodiazepine
CS521788A1 (en) Derivatives of trimethoprine