IL90300A - Substituted aminobenzonitriles - Google Patents

Substituted aminobenzonitriles

Info

Publication number
IL90300A
IL90300A IL90300A IL9030085A IL90300A IL 90300 A IL90300 A IL 90300A IL 90300 A IL90300 A IL 90300A IL 9030085 A IL9030085 A IL 9030085A IL 90300 A IL90300 A IL 90300A
Authority
IL
Israel
Prior art keywords
aminobenzonitriles
substituted
substituted aminobenzonitriles
Prior art date
Application number
IL90300A
Other languages
English (en)
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/664,731 external-priority patent/US4631286A/en
Priority claimed from US06/781,155 external-priority patent/US4695573A/en
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL90300A publication Critical patent/IL90300A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL90300A 1984-10-25 1985-10-23 Substituted aminobenzonitriles IL90300A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/664,731 US4631286A (en) 1984-10-25 1984-10-25 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US06/781,155 US4695573A (en) 1984-10-25 1985-10-01 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
IL76796A IL76796A (en) 1984-10-25 1985-10-23 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds,a process for their preparation and medicaments containing them

Publications (1)

Publication Number Publication Date
IL90300A true IL90300A (en) 1990-11-29

Family

ID=27099040

Family Applications (3)

Application Number Title Priority Date Filing Date
IL90300A IL90300A (en) 1984-10-25 1985-10-23 Substituted aminobenzonitriles
IL76796A IL76796A (en) 1984-10-25 1985-10-23 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds,a process for their preparation and medicaments containing them
IL8990300A IL90300A0 (en) 1984-10-25 1989-05-15 Substituted aminobenzonitriles

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL76796A IL76796A (en) 1984-10-25 1985-10-23 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds,a process for their preparation and medicaments containing them
IL8990300A IL90300A0 (en) 1984-10-25 1989-05-15 Substituted aminobenzonitriles

Country Status (20)

Country Link
US (1) US4839364A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0179383B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH01125362A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR900007624B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR247394A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE63903T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU589141B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1292744C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3582995D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (2) DK167250B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (3) ES8701165A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI86421C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR852555B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU196183B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE58696B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (3) IL90300A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO172847C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (2) NZ229248A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH22614A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT81362B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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US4753950A (en) * 1986-11-24 1988-06-28 Hoechst-Roussel Pharmaceuticals, Inc. Fused heterocyclic tetrahydroaminoquinolinols and related compounds
US4897400A (en) * 1987-02-13 1990-01-30 Hoeschst-Roussel Pharmaceuticals, Inc. 9-amino-1,4-ethano-1,2,3,4-tetrahydroacridine and related compounds useful for incresing the cholinergic function in a mammal
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US4762841A (en) * 1987-03-30 1988-08-09 Hoechst-Roussel Pharmaceuticals Inc. Substituted 9-amino-spiro(cycloalkyl(b)quinoline-2,1'cycloalkanes)
ES2058167T3 (es) * 1987-04-20 1994-11-01 Hoechst Roussel Pharma 9-hidroxiamino-tetrahidro-acridinas, un procedimiento para su preparacion y su uso como medicamentos.
US6075144A (en) 1987-04-20 2000-06-13 Hoechst Marion Roussel, Inc. 9-hydroxyamino tetrahydroacridine and related compounds
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KR0156241B1 (ko) * 1988-11-16 1998-11-16 도날드 알.토센 하이드록시-1,2,3,4-테트라하이드로아미노아크리딘, 이의 제조방법 및 이를 함유하는 약제학적 조성물
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine
GB8827704D0 (en) * 1988-11-28 1988-12-29 Fujisawa Pharmaceutical Co New acridine derivatives & processes for their production
US5280032A (en) * 1989-02-14 1994-01-18 Toyama Chemical Co., Ltd. 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
US5053513A (en) * 1990-03-29 1991-10-01 Hoechst-Roussel Pharmaceuticals Incorporated Method of reducing a carbonyl containing acridine
US5210087A (en) * 1991-02-13 1993-05-11 Hoechst-Roussel Pharmaceuticals Inc. 9-aminotetrahydroacridines and related compounds
RU2024509C1 (ru) * 1991-05-07 1994-12-15 Всероссийский научный центр по безопасности биологически активных веществ Производные 9-аминоакридина или их соли с органическими или неорганическими кислотами, проявляющие психотропную, антиамнестическую и липидрегулирующую активность
GB2264707A (en) * 1991-06-18 1993-09-08 Roger Michael Marchbanks Acridine derivatives for treating alzheimer's disease
US5434165A (en) * 1991-11-18 1995-07-18 Sanawa Kagaku Kenkyusho Company, Ltd. Nootropic agents, compositions of, and method of use thereof
JP2873898B2 (ja) * 1992-04-13 1999-03-24 富山化学工業株式会社 ベンゾ［ｂ］チオフェン−５−イル誘導体もしくはその光学活性体またはそれらの塩並びにそれらの製造法
US5247091A (en) * 1992-07-30 1993-09-21 Hoechst Celanese Corporation Preparation of enamines in aqueous media
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
ES2059263B1 (es) * 1992-10-27 1995-10-01 Vita Invest Sa Procedimiento para la obtencion del (+)-9-amino-1,2,3,4-tetrahidroacridin-1-ol.
CA2161538A1 (en) * 1993-07-22 1995-02-02 S. Shirley Yang Controlled release tacrine drug delivery systems and methods for preparing same
US5434170A (en) * 1993-12-23 1995-07-18 Andrulis Pharmaceuticals Corp. Method for treating neurocognitive disorders
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
DE19707655A1 (de) * 1997-02-26 1998-08-27 Hoechst Ag Kombinationspräparat zur Anwendung bei Demenz
ES2144353B1 (es) * 1997-12-26 2001-01-01 Consejo Superior Investigacion Nuevos analogos de tacrina: potenciales agentes neuroprotectores para las enfermedades de alzheimer y parkinson. su procedimiento de obtencion.
KR100381716B1 (ko) * 2000-10-09 2003-04-26 한국화학연구원 항암활성을 가지는 아크리딘 유도체
WO2005072713A2 (en) 2004-01-27 2005-08-11 The Feinstein Institute For Medical Research Cholinesterase inhibitors for treating inflammation
EP1779867A4 (en) * 2004-07-01 2009-12-02 Eisai R&D Man Co Ltd MEANS FOR PROMOTING NERVE REVENERATION
CA2589102C (en) * 2004-11-02 2013-08-13 Northwestern University Pyridazine compounds and methods for using the compounds to treat inflammatory diseases
EP1828111A2 (en) * 2004-11-12 2007-09-05 Neurochem (International) Limited Methods and fluorinated compositions for treating amyloid-related diseases
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
CN106061948A (zh) * 2014-01-15 2016-10-26 国家科学研究中心 水溶性的4‑氮杂鬼臼毒素类似物
KR101586473B1 (ko) * 2014-04-30 2016-01-19 (주)이컴프 스크롤 압축기
RU2567388C1 (ru) * 2014-12-10 2015-11-10 Открытое акционерное общество "Нижегородский химико-фармацевтический завод" Способ получения 9-бутиламино-3,3-диметил-3,4-дигидроакридин-1(2н)-она гидрохлорида
CN115947686B (zh) * 2022-12-05 2024-11-12 浙江工业大学 一类9-氨基-3,4-二氢吖啶-1(2h)-酮类化合物及其应用

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PL101032B1 (pl) * 1976-04-06 1978-11-30 Sposob otrzymywania 1-nitro-9-dwualkilo-aminoizoalkiloamiroakrydyn lub ich soli
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EP0179383B1 (en) * 1984-10-25 1991-05-29 Hoechst-Roussel Pharmaceuticals Incorporated 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments
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DK569087A (da) * 1986-10-31 1988-05-01 Sumitomo Pharma Quinolin-derivater, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
AU589141B2 (en) 1989-10-05
ES548137A0 (es) 1986-11-16
KR860003227A (ko) 1986-05-21
ES554569A0 (es) 1988-01-01
EP0179383A3 (en) 1987-01-28
CA1292744C (en) 1991-12-03
AU615768B2 (en) 1991-10-10
AU4903885A (en) 1986-05-01
JPH01125362A (ja) 1989-05-17
ES554568A0 (es) 1988-05-16
FI854156A0 (fi) 1985-10-23
FI86421C (fi) 1992-08-25
PT81362B (pt) 1987-11-30
NZ229248A (en) 1990-12-21
AR247394A1 (es) 1994-12-29
NO904711L (no) 1986-04-28
EP0179383B1 (en) 1991-05-29
ES8802383A1 (es) 1988-05-16
DK141992A (da) 1992-11-26
PT81362A (en) 1985-11-01
EP0179383A2 (en) 1986-04-30
IL76796A (en) 1990-03-19
IL76796A0 (en) 1986-02-28
AU3823489A (en) 1989-10-26
NO904711D0 (no) 1990-10-30
ATE63903T1 (de) 1991-06-15
DK488885A (da) 1986-04-26
NO172847C (no) 1993-09-15
IE58696B1 (en) 1993-11-03
DE3582995D1 (de) 1991-07-04
JPH0584306B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-12-01
PH22614A (en) 1988-10-17
GR852555B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-02-24
DK141992D0 (da) 1992-11-26
ES8801213A1 (es) 1988-01-01
KR900007624B1 (ko) 1990-10-17
HU196183B (en) 1988-10-28
FI86421B (fi) 1992-05-15
HUT41009A (en) 1987-03-30
DK168704B1 (da) 1994-05-24
DK167250B1 (da) 1993-09-27
NO172847B (no) 1993-06-07
US4839364A (en) 1989-06-13
IL90300A0 (en) 1989-12-15
FI854156L (fi) 1986-04-26
ES8701165A1 (es) 1986-11-16
DK488885D0 (da) 1985-10-24
IE852632L (en) 1986-04-25
NZ213932A (en) 1990-12-21

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